2,220 research outputs found
Experimental Wear Modelling of Lifeboat Slipway Launches
It is necessary to use an inclined slipway to launch lifeboats in locations where there is no natural harbour. Slipway stations consist of an initial roller section followed by an inclined keelway, the lifeboat is released from the top of the slipway and proceeds under its own weight into the water. Contact is between the lifeboat keel and a lined, greased keelway and this that determines the friction along the slipway. This paper describes a bench test methodology to investigate this contact. The selection of a modified TE57 reciprocating tribometer and design of a modified pin on plate arrangement is discussed. A test schedule for both the original nickel/chromium coated steel lining and the new low-friction jute fibre/phenolic resin composite lining is developed to accurately reflect real world conditions including environmental contamination such as seawater or wind-blown sand. Environmentally conscious lubricants including water and bio-greases are investigated and compared for their effects in reducing slipway panel friction and wear. Experimental data is collected to establish wear mechanisms, wear volumes and friction characteristics for a range of lubricants and environmental contaminants for the two most common lifeboat keelway lining materials. Implications of this research for future lifeboat slipway design are discussed
Rh-catalyzed arylation of fluorinated ketones with arylboronic acids
The Rh-catalyzed arylation of fluorinated ketones with boronic acids is reported. This efficient process allows access to fluorinated alcohols in high yields under mild conditions. Competition experiments suggest that difluoromethyl ketones are more reactive than trifluoromethyl ketones in this process, despite their decreased electronic activation, an effect we postulate to be steric in origin
Structural disorder versus chiral magnetism in CrNbS
The crystal structure of a disordered form of CrNbS has been
characterized using diffraction and inelastic scattering of synchrotron
radiation. In contrast to the previously reported symmetry (P622), the
crystal can be described by a regular twinning of an average P6 structure
with three disordered positions of the Cr ions. Short-range correlations of the
occupational disorder result in a quite intense and structured diffuse
scattering; a static nature of the disorder was unambiguously attributed by the
inelastic x-ray scattering. The diffuse scattering has been modeled using a
reverse Monte-Carlo algorithm assuming a disorder of the Cr sub-lattice only.
The observed correlated disorder of the Cr sub-lattice reduces the temperature
of the magnetic ordering from 130 K to 88 K and drastically modifies the field
dependence of the magnetization as it is evidenced by the SQUID magnetometery.
We conclude, that in contrast to the helicoidal spin structure assumed for
P622 form, the compound under study is ferromagnetically ordered with a
pronounced in-plane anisotropy
Targets and self monitoring in hypertension: randomised controlled trial and cost effectiveness analysis
Objectives: To assess whether blood pressure control in primary care could be improved with the use of patient held targets and self monitoring in a practice setting, and to assess the impact of these on health behaviours, anxiety, prescribed antihypertensive drugs, patients’ preferences, and costs. \ud
Design: Randomised controlled trial. \ud
Setting: Eight general practices in south Birmingham. \ud
Participants: 441 people receiving treatment in primary care for hypertension but not controlled below the target of < 140/85 mm Hg. \ud
Interventions: Patients in the intervention group received treatment targets along with facilities to measure their own blood pressure at their general practice; they were also asked to visit their general practitioner or practice nurse if their blood pressure was repeatedly above the target level. Patients in the control group received usual care (blood pressure monitoring by their practice). \ud
Main outcome measures: Primary outcome: change in systolic blood pressure at six months and one year in both intervention and control groups. Secondary outcomes: change in health behaviours, anxiety, prescribed antihypertensive drugs, patients’ preferences of method of blood pressure monitoring, and costs. \ud
Results: 400 (91%) patients attended follow up at one year. Systolic blood pressure in the intervention group had significantly reduced after six months (mean difference 4.3 mm Hg (95% confidence interval 0.8 mm Hg to 7.9 mm Hg)) but not after one year (mean difference 2.7 mm Hg (-ï€ 1.2 mm Hg to 6.6 mm Hg)). No overall difference was found in diastolic blood pressure, anxiety, health behaviours, or number of prescribed drugs. Patients who self monitored lost more weight than controls (as evidenced by a drop in body mass index), rated self monitoring above monitoring by a doctor or nurse, and consulted less often. Overall, self monitoring did not cost significantly more than usual care (£251 ($437; 364 euros) (95% confidence interval £233 to £275) versus £240 (£217 to £263). \ud
Conclusions: Practice based self monitoring resulted in small but significant improvements of blood pressure at six months, which were not sustained after a year. Self monitoring was well received by patients, anxiety did not increase, and there was no appreciable additional cost. Practice based self monitoring is feasible and results in blood pressure control that is similar to that in usual care. \u
Hanging In, Stepping up and Stepping Out: Livelihood Aspirations and Strategies of the Poor Development in Practice
In recent years understanding of poverty and of ways in which people escape from or fall into poverty has become more holistic. This should improve the capabilities of policy analysts and others working to reduce poverty, but it also makes analysis more complex. This paper describes a simple schema which integrates multidimensional, multilevel and dynamic understandings of poverty, of poor people’s livelihoods, and of changing roles of agricultural systems. The paper suggests three broad types of strategy pursued by poor people: ‘hanging in’; ‘stepping up’; and ‘stepping out’. This simple schema explicitly recognises the dynamic aspirations of poor people; diversity among them; and livelihood diversification. It also brings together aspirations of poor people with wider sectoral, inter-sectoral and macro-economic questions about policies necessary for realisation of those aspirations
Protocol for a mixed-methods exploratory investigation of care following intensive care discharge: the REFLECT study
© Author(s) 2019. Re-use permitted under CC BY. Published by BMJ.INTRODUCTION: A substantial number of patients discharged from intensive care units (ICUs) subsequently die without leaving hospital. It is unclear how many of these deaths are preventable. Ward-based management following discharge from ICU is an area that patients and healthcare staff are concerned about. The primary aim of REFLECT (Recovery Following Intensive Care Treatment) is to develop an intervention plan to reduce in-hospital mortality rates in patients who have been discharged from ICU. METHODS AND ANALYSIS: REFLECT is a multicentre mixed-methods exploratory study examining ward care delivery to adult patients discharged from ICU. The study will be made up of four substudies. Medical notes of patients who were discharged from ICU and subsequently died will be examined using a retrospective case records review (RCRR) technique. Patients and their relatives will be interviewed about their post-ICU care, including relatives of patients who died in hospital following ICU discharge. Staff involved in the care of patients post-ICU discharge will be interviewed about the care of this patient group. The medical records of patients who survived their post-ICU stay will also be reviewed using the RCRR technique. The analyses of the substudies will be both descriptive and use a modified grounded theory approach to identify emerging themes. The evidence generated in these four substudies will form the basis of the intervention development, which will take place through stakeholder and clinical expert meetings. ETHICS AND DISSEMINATION: Ethical approval has been obtained through the Wales Research and Ethics Committee 4 (17/WA/0107). We aim to disseminate the findings through international conferences, international peer-reviewed journals and social media. TRIAL REGISTRATION NUMBER: ISRCTN14658054.Peer reviewedFinal Published versio
Cooperative Jahn-Teller Distortion in PrO2
We report neutron diffraction data on single crystal PrO2 which reveal a
cooperative Jahn-Teller distortion at TD = 120 +/- 2 K. Below this temperature
an internal distortion of the oxygen sublattice causes the unit cell of the
crystallographic structure to become doubled along one crystal axis. We discuss
several possible models for this structure. The antiferromagnetic structure
below TN = 13.5 K is found to consist of two components, one of which shares
the same doubled unit cell as the distorted crystallographic structure. We also
present measurements of the magnetic susceptibility, the specific heat capacity
and the electrical conductivity of PrO2. The susceptibility data show an
anomaly at a temperature close to TD. From the specific heat capacity data we
deduce that the ground state is doubly degenerate, consistent with a distortion
of the cubic local symmetry. We discuss possible mechanisms for this. The
conductivity shows an activated behaviour with an activation energy Ea = 0.262
+/- 0.003 eV.Comment: 12 pages, 14 figures, 2 tables. Additional suggested structure in v
Adjusting for Network Size and Composition Effects in Exponential-Family Random Graph Models
Exponential-family random graph models (ERGMs) provide a principled way to
model and simulate features common in human social networks, such as
propensities for homophily and friend-of-a-friend triad closure. We show that,
without adjustment, ERGMs preserve density as network size increases. Density
invariance is often not appropriate for social networks. We suggest a simple
modification based on an offset which instead preserves the mean degree and
accommodates changes in network composition asymptotically. We demonstrate that
this approach allows ERGMs to be applied to the important situation of
egocentrically sampled data. We analyze data from the National Health and
Social Life Survey (NHSLS).Comment: 37 pages, 2 figures, 5 tables; notation revised and clarified, some
sections (particularly 4.3 and 5) made more rigorous, some derivations moved
into the appendix, typos fixed, some wording change
Impact hammer-based analysis of nonlinear effects in bolted lap joint
This work presents an experimental investigation into the dynamic behavior of a bolted joint beam configuration. The impact hammer is chosen as an alternative to classical harmonic excitation methods. The structural responses are explored for a range of the joint tightening toques and various levels of impulse hammer excitations. A symmetric beam assembly made of two nominally identical steel beams is studied. Symmetric modes are found to be sensitive to the test parameters. For given torque, impact-based varying joint loading conditions are used to induce the nonlinear joint effects. A linear data processing strategy is used to observe the nonlinear behavior indirectly. The dynamic joint behavior is described in the form of the modal frequency-damping ratio performance maps represented by the two-parametric approximating quadratic response surface models. This model maps the joint conditions on the corresponding dynamic characteristics of interest and it will serve as a basis for the parametric linear joint model developmen
Association of soil bacterial diversity and composition with Fusarium wilt disease of bananas in Yogyakarta Province, Indonesia
Infection of banana plants with Fusarium oxysporum f. sp. cubense Tropical Race 4 (Foc-TR4) leads to a cascade of changes in the rhizosphere, resulting in changes to the soil physicochemical properties and bacterial community composition. This study aimed to determine the core taxa associated with different soil physicochemical properties and disease statuses and to identify the factors exerting the greatest influence on the soil bacterial community composition of bananas in Special Region of Yogyakarta Province, Indonesia. Rhizospheric soil from healthy and infected plants was collected from four banana locations, including Kulon Progo, Gunungkidul, Bantul, and Sleman districts, at 10-30 cm depth between May and September 2021. Laboratory analysis was conducted for soil physicochemical properties, and the abundance of Foc-TR4 was undertaken. Additionally, 16S rRNA gene-based metagenomics analysis was used to quantify bacterial diversity in all samples. Soil type significantly influenced the abundance and composition of the bacterial community more than disease status did. Contrarily, disease status groups influenced the complexity of bacterial network interaction more than soil type. Actinobacteriota, Proteobacteria, Chloroflexi, Acidobacteriota, and Bacteriodota are the major phyla associated with all soils. This study identified 60 bacterial genera as core members of the banana rhizosphere. These core bacterial genera include various plant growth-promoting bacteria involved in nitrogen fixation, phytohormone production, siderophore production, and biocontrol mechanisms for producing antifungal compounds. Our work provides a basis for future research on the soil bacterial composition associated with banana plants to enhance plant health against Fusarium wilt disease. © 2024, Society for Indonesian Biodiversity. All rights reserved
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