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Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
- Author
- Abbass Hakam
- Adhikari Neill
- Affleck Julia
- Agno Sathianathan Ronan
- Ahmad Norfaizan
- Ahmed Iram
- Ainscough Kate
- Al Qasim Eman
- Al Swaidan Lolowa
- Al-Bassam Wisam
- Al-Beidh Farah
- Al-Beidh Farah
- Albert Martin
- Alegria Ana
- Alexander Brian
- Alexander Peter
- Allan Angela
- Allan Elizabeth
- Allen Louise
- Allibone Suzanne
- Amaro dos Santos Catorze Teodoro
- Anderson Tom
- Andric Zdravko
- Angus Derek
- Angus Derek C
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Annane Djillali
- Anstey Matthew
- Antcliffe David
- Aparicio Christelle
- Appelt Peter
- Arabi Yaseen
- Arabi Yaseen
- Arbane Gill
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arishi Hatim
- Arnold Donald
- Asghar Adeeba
- Ashelford Angela
- Attwood Ben
- Austin Karen
- Aysel Florescu Simin
- Azaiz Amine
- Babel Jakša
- Babio-Galan Maite
- Badie Julio
- Bagshaw Sean
- Baillie Kenneth
- Baker Evelyn
- Bakthavatsalam Dhanalakshmi
- Bamford Peter
- Banach Dorota
- Bannard-Smith Jonathan
- Barbazza Leanne
- Barber Russell
- Barge Deborah
- Barnes Nicky
- Baršić Bruno
- Bashyal Archana
- Basile Kim
- Bass Frances
- Bates Michelle
- Bauchmuller Kris
- Bean Sarah
- Beane Abigail
- Beane Abigail
- Beasley Richard
- Begin Phillipe
- Bellemare David
- Benettaib Fatna
- Benzekri Dalila
- Berdaguer Fernando Daniel
- Bergin Colin
- Berry Lindsay
- Berry Lindsay
- Berry Scott
- Berry Scott
- Bhimani Zahra
- Bhimani Zahra
- Bihari Shailesh
- Bihari Shilesh
- Binnie Alexandra
- Bion Julian
- Biradar Vishwanath
- Birch Janine
- Birch Jenny
- Birchall Katie
- Birkinshaw Isobel
- Black Ethel
- Bloos Frank
- Board Jasmin
- Bone Allsion
- Bonner Stephen
- Bonten Marc
- Bonten Marc
- Borgatta Barbara
- Borrill Zoe
- Bosch Ziekenhuis Jeroen
- Boschert Catherine
- Bossard Isabelle
- Boumahni Dounia
- Bourgoin Charlotte
- Bourne Michelle
- Bourne Richard
- Bouwman Wietske
- Bowler Helen
- Boyd Craig
- Bracke Stephanie
- Bradbury Charlotte
- Bradbury Charlotte
- Bradley-Potts Joanne
- Brailsford Jane
- Brain Matthew
- Brant Emily
- Breen Patrick
- Brett Stephen
- Brewer Chris
- Brickell Kathy
- Brightling Chris
- Brillinger Nicole
- Brimfield Lutece
- Brinkerhoff Gail
- Brochard Laurent
- Brohi Farooq
- Browne Troy
- Brunkhorst Frank
- Brunkhorst Frank
- Budd Joanna
- Buehner Ulrike
- Buhr Heidi
- Bullman Laetitia
- Burns Karen
- Burt Karen
- Buscher Hergen
- Butler Amelia
- Butler M
- Buxton Meredith
- Buxton Meredith
- Buzgau Adrian
- Byrne Deborah
- Byrne Kathleen
- Bélteczki János
- Cabreros Leilani
- Calfee Carolyn
- Callender Owen
- Campbell Andy
- Campbell Hilary
- Campbell Lewis
- Camsooksai Julie
- Caplin Cecile
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- Carr-Knott Lisa
- Carrier François Martin
- Carrier Marc
- Cartner Brittney
- Casey Ruth
- Casey Siobhan
- Castro Ferreira Ricardo Manuel
- Cate Heidi
- Cathcart Susanne
- Cavayas Alexandros
- Cawley Kathryn
- Cazzola Federica
- Centofanti John
- Chablani Manish
- Chamara Warnapura Loku
- Chan Carmen
- Chan Charles
- Chan Peter
- Charlewood Richard
- Charron Cyril
- Chartier Delphine
- Chasse Michael
- Chassé Michaël
- Chen Yan
- Cheng Allen
- Cheng Allen C
- Cherian Shiney
- Cheung Winston
- Chhablani Manish
- Chudeau Nicolas
- Cirstea Emanuel
- Clarey Emma
- Claridge Helen
- Clark Michele
- Clark Sarah
- Claxton Andrew
- Clermont Giles
- Cloutier Ève
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- Codreanu Daniel
- Coghlan Phoebe
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- Coles Jennifer
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- Collier Dawn
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- Collins Joanne
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- Cooper Melanie
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- Cowley Nicholas
- Cowton Amanda
- Coyne Mark
- Craner Michelle
- Craven Thomas
- Creagh-Brown Ben
- Crisp Nikki
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- Cutler Sean
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- Darreau Cédric
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- Davies Gwyneth
- Davies Louisa
- Davies Michelle
- Dawda Ashlish
- Day Christopher
- De Beaux Fiona
- De Bus Liesbet
- de Courcy-Golder Kim
- de Jager P
- de Jong Menno
- De Jong Menno
- de Jonge E
- de la Fuente Martos Carmen
- de Lima Pereira Tiago Nuno Alfaro
- de Man Angelique
- De Waele Jan
- Dearden Joy
- Dechert William
- Deelchand Vashish
- Dela Rosa Arnold
- Dell Amanda
- Demetriou Carrie
- Depante Maria Theresa
- Depuydt Pieter
- Dequin PierreFrançois
- Derde Lennie
- Derde Lennie
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- Detry Michelle
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- Doble Patricia
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- Drummond Andrew
- Duan Erick
- Duffy Eamon
- Duke Graeme
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- Dushianthan Ahilanandan
- Dyas Sarah
- D’Aragon Frédérick
- D’Souza Ramsy
- Effelaar Evelien
- Elhassan Munzir
- Elin Hall Rebecca
- Ellis Christine
- Elmahi Einas
- Elsefi Tarek
- English Shane
- Estcourt Lise
- Estcourt Lise
- Estensen Kristen
- Everitt Robert
- Evers Mirjam
- Farahi Neda
- Fartoukh Muriel
- Faulkner Beverley
- Faulkner Maria
- Fazekas Ágnes
- Felton Tim
- Ferguson Niall
- Ferguson Susan
- Fergusson Dean
- Fernández de Pinedo Artaraz Ziortza
- Ferrier Janet
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- Finn Stephanie
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- Fitzgerald Mark
- Fitzgerald Mark
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- Flint Neil
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- Forbes Loretta
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- Fowler Rob
- Fowler Robert
- Fox Claire
- Francia Federica
- Francoeur Charles
- Frey Anna
- Friedrich Hinrichs Carl
- Frohlich Stephen
- Fysh Ed
- Gallagher Linda Jude
- Ganguly Saibal
- Ganpat Radhika
- Garcia Rebecca
- Gardiner-Hill Caroline
- Garrard Hywel
- Garrard William
- Gates Simon
- Gattas David
- Gellamucho Minerva
- Gendall Emma
- Genetu Roman Mary
- Geng Wenli
- Geri Guillaume
- Ghamraoui Ali
- Ghosh Alison
- Gibson Charly
- Girard Timothy
- Girijadevi Dinu
- Gledhill Lisa
- Godement Mathieu
- Golden David
- Goligher Ewan
- Gomm Linda
- Goodson Jennifer
- Goodwin Jayne
- Goossens Herman
- Goossens Herman
- Gopal Shameer
- Gopinath Amitha
- Gordon Anthony
- Gordon Anthony C
- Gordon Elizabeth
- Gosbell Iain
- Gould Richard
- Grecu Irina
- Green Cameron
- Green Cameron
- Gregory Jane
- Gresha Rebecca
- Grimmer Lisa
- Grimwade Kate
- Guilder E
- Guitton Christophe
- Hacking Danielle
- Hadebe Bernard
- Hagel Stefan
- Haidar Ghady
- Hall Andrew
- Hall Kathryn
- Hamilton David Oliver
- Hamilton-Davies Colin
- Hamlyn Vincent
- Hammond Naomi
- Haniffa Rashan
- Haniffa Rashan
- Hanson Jane
- Harford Rachel
- Harland Cain
- Harrington Kate
- Harris Nichola
- Harrison Susie
- Hart Ciaran
- Harvala-Simmonds Heli
- Harvey Daniel
- Harward Meg
- Hawcutt Daniel
- Hawkins Nancy
- Hay Sophie Kennedy
- Hayes Kati
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- Hays Carole
- Health Monash
- Heinonen Jonna
- Heming Nicholas
- Henderson Seton
- Henderson Steven
- Henning Jeremy
- Henry Joanne
- Heritier Stephane
- Hickey Naomi
- Higgins Alisa M
- Higgins Lisa
- Hill Helen
- Hills Thomas
- Hills Tom
- Hird Clare
- Hodgson Carol
- Hoff Uwe
- Hoiting Oscar
- Holland Nicky
- Hollos Laszlo
- Homes Jennifer
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- Hopkins Phil
- Hormis Anil
- Horton Michelle
- Horton Sarah
- Horvat Christopher
- Horvat Christopher
- Howcroft Clare
- Howle Ryan
- Huang David
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- Hughes Emma
- Hugill Keith
- Hullegie Sebastiaan
- Hullegie Sebastiaan J
- Hulley Amanda
- Hulme Jonathan
- Hunt Beverley
- Hunter Stephanie
- Hutter Joanne
- Hutton Paula
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- Ireland Jane
- Isgro Graziella
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- Jackson Matthew
- Jackson Shane
- Jackson Susan
- Jacques Nicola
- Jacquier Sophie
- Jagannathan Vijay
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- Jarczak Dominik
- Jeblaoui Asma
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- Jenkins Sarah
- Jha Rajeev
- Jhanji Shaman
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- Johnson David
- Johnson Rebekah
- Johnston Paul
- Jones Andrea
- Jones Jo
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- Juhaz Vera
- Kalchthaler Kyle
- Kalogirou Michael
- Kamel Toufik
- Karachi Tim
- Karlikowski Michal
- Karlsson Sari
- Kasipandian Vidya
- Kayani Abdul
- Kazemi Alex
- Keen Alexandra
- Keenan Samantha
- Keet Owen
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- Kelly Martin
- Kelsall Olivia
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- Khare Divya
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- Kirkby Amy
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- Kosa Alma Gabriela
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- Krishnamurthy Vinodh
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- Kruger Peter
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- Kumar Anand
- Kumar Nikhil
- Kunz Kevin
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- KyereDiabour Thyra
- Kyeremeh Lynsey
- Labbe Vincent
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- Lamonagne Francois
- Lamontagne Francois
- Lamontagne Francois
- Lamontagne François
- Landais Mickaël
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- Laver Russell
- Lawler Patrick
- Lawler Patrick R
- Lawless Patrick
- Lazaro Juan Martin
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- Lee Stephanie
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- Lewis Roger
- Lewis Roger J
- Lewis Sarah
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- Linstrum Kelsey
- Litton Ed
- Litton Edward
- Litton Edward
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- Lorenzi Elizabeth
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- Lowe Benjamin
- Lowrey Julie
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- Mackay Euan
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- Magyar István
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- Mandadapu Vineela
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- Marroquin Oscar
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- Marshall Nicola
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- McAuley Daniel
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- Mouncey Paul
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- Murthy Srinivas
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- Scully Michael
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- Seymour Christopher
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- Simmonds Catherine
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- Tallott Mandy
- Tatham Kate Colette
- Templeton Maie
- Thomas Amy
- Thomas Helen
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- Thomas Matthew
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- Thomson Nicola
- Thrush Jessica
- Tilney Emma
- Tinmouth Alan
- Tong Steve
- Tooley Joe
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- Trask Kara
- Triulzi Darrell
- Trodd Dawn
- Tsang Jennifer
- Tully Redmond
- Turgeon Alexis
- Turki Salah
- Turner Anne
- Turner Anne
- Turner-Bone Ian
- Turns Margaret
- Uddin Ruzena
- Udy Andrew
- Uyeki Tim
- Vaara Suvi
- Vahtera Annukka
- Vamplew Luke
- van Bentum Puijk Wilma
- van Bentum-Puijk Wilma
- van Bentum-Puijk Wilma
- van Beurden Marloes
- van de Veerdonk Frank
- van de Veerdonk Frank
- Van Der Heyden Kym
- van der Poll Tom
- van’t Hoff Willian
- Vates Jennifer
- Vautier Sarah
- Vazquez-Grande Gloria
- Venkatesh Bala
- Venkatesh Balasubramanian
- Venz Ellen
- Verlander Mark
- Verrier Nathalie
- Victor Saji
- Vieillard-Baron Antoine
- Voicu Sebastian
- Vowell Emma
- Vujaklija Brajković Ana
- Vuylsteke Alain
- Wagh Atul
- Walden Andrew
- Walker Rachel
- Walsh Joanne
- Walsh Tim
- Walsham James
- Ward Kathryn
- Warnock Majella
- Waterson Sharon
- Watkins Claire
- Watpool Irene
- Watters Malcolm
- Waugh Victoria
- Webb Steve
- Webb Steven A
- Wedd Steve
- Weismann Dirk
- Weissman Alexandra
- Wells Colin
- Welters Ingeborg
- Wetherill Bill
- Whelan Ruth
- Whileman Amanda
- Whitbread Jennifer
- White Hayden
- White Ian
- White Katie
- Whitehead Christina
- Wibrow Bradley
- Wigbers J
- Wilby Elizabeth
- Wild Laura
- Wild Laura
- Wilding Laura
- Wiley Daisy
- Wilhelmsen Elva
- Wilkinson Dean
- Willams Felicity
- Williams Alexandra
- Williams Erin
- Williams Hannah
- Williams Karen
- Williams Patricia
- Williams Patricia
- Williams Penny
- Williams Tony
- Williams Virginie
- Williamson Dawn
- Williamson James
- Wilson Karen
- Wilson Maggie
- Wiseman Sophie
- Wong Helen
- Wood Erica
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wrey Brown Caroline
- Writing Committee for the REMAP-CAP Investigators
- Xavier Kugan
- Xia Le Tai Charlotte
- Yarad Elizabeth
- Yates David
- Young Chelsea
- Young Ian
- Young Meredith
- Young Paul
- Yusuff Hakeem
- Zaharia Miahela Florentina
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zammit Claire
- Zapalac Marija
- Zarychanski Ryan
- Zarychanski Ryan
- Zhao Xiao Bei
- Zinzoni Vanessa
- Zitter Letizia
- Đimoti Renata
- Publication venue
- JAMA: Journal of the American Medical Association
- Publication date
- 06/10/2020
- Field of study
Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin. Between March 9 and June 17, 2020, 614 adult patients with suspected or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission to an intensive care unit (ICU) for respiratory or cardiovascular organ support at 121 sites in 8 countries. Of these, 403 were randomized to open-label interventions within the corticosteroid domain. The domain was halted after results from another trial were released. Follow-up ended August 12, 2020. Interventions: The corticosteroid domain randomized participants to a fixed 7-day course of intravenous hydrocortisone (50 mg or 100 mg every 6 hours) (n = 143), a shock-dependent course (50 mg every 6 hours when shock was clinically evident) (n = 152), or no hydrocortisone (n = 108). Main Outcomes and Measures: The primary end point was organ support-free days (days alive and free of ICU-based respiratory or cardiovascular support) within 21 days, where patients who died were assigned -1 day. The primary analysis was a bayesian cumulative logistic model that included all patients enrolled with severe COVID-19, adjusting for age, sex, site, region, time, assignment to interventions within other domains, and domain and intervention eligibility. Superiority was defined as the posterior probability of an odds ratio greater than 1 (threshold for trial conclusion of superiority >99%). Results: After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60 years; 29% female) randomized to the fixed-dose (n = 137), shock-dependent (n = 146), and no (n = 101) hydrocortisone groups; 379 (99%) completed the study and were included in the analysis. The mean age for the 3 groups ranged between 59.5 and 60.4 years; most patients were male (range, 70.6%-71.5%); mean body mass index ranged between 29.7 and 30.9; and patients receiving mechanical ventilation ranged between 50.0% and 63.5%. For the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively, the median organ support-free days were 0 (IQR, -1 to 15), 0 (IQR, -1 to 13), and 0 (-1 to 11) days (composed of 30%, 26%, and 33% mortality rates and 11.5, 9.5, and 6 median organ support-free days among survivors). The median adjusted odds ratio and bayesian probability of superiority were 1.43 (95% credible interval, 0.91-2.27) and 93% for fixed-dose hydrocortisone, respectively, and were 1.22 (95% credible interval, 0.76-1.94) and 80% for shock-dependent hydrocortisone compared with no hydrocortisone. Serious adverse events were reported in 4 (3%), 5 (3%), and 1 (1%) patients in the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively. Conclusions and Relevance: Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority with regard to the odds of improvement in organ support-free days within 21 days. However, the trial was stopped early and no treatment strategy met prespecified criteria for statistical superiority, precluding definitive conclusions. Trial Registration: ClinicalTrials.gov Identifier: NCT02735707
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Abbas Rezaianzadeh
- Abdonas Tamosiunas
- Abdul Basit
- Abdul Hamid Zargar
- Abdullah Alkandari
- Abdullatif Husseini
- Abhijit Sen
- Abla M Sibai
- Abu Am Hanif
- Adela Chirita-Emandi
- Adelheid Weber
- Adetoyeje Y Oyeyemi
- Adewale L Oyeyemi
- Adolfo Rubinstein
- Adoubi Kassi Anicet
- Adroaldo Cesar Araujo Gaya
- Afshin Ostovar
- Agnes L Kadvan
- Agneta Sjöberg
- Agneta Yngve
- Agnès Le Port
- Agustinus Soemantri
- Agustín Perez-Londoño
- Ahmad A Zainuddin
- Ahmad Faudzi Yusoff
- Ahmad Reza Dorosty
- Ahmed A Madar
- Aida Pilav
- Aïcha Soumaré
- Akaninyene Otu
- Akihiro Yoshihara
- Akkumis Salhanova
- Akram Pourshams
- Ala'a Alkerwi
- Alain Morejon
- Alanna G da Silva
- Albertino Damasceno
- Alberto Barceló
- Alberto Palloni
- Albina A Fakhretdinova
- Alejandro Diaz
- Aleksander Giwercman
- Aleksandra Gomula
- Aleksandra Piwonska
- Alessandro Gialluisi
- Aletta E Schutte
- Alexander D Deev
- Alexandra M Cucu
- Alexandre C Pereira
- Alfonso Siani
- Alfonso Sousa-Poza
- Ali Ahmadi
- Ali Akbar Shayesteh
- Ali Esmaeili
- Ali Ghanbari
- Ali Reza Safarpour
- Alice Bonilla-Vargas
- Alicia Matijasevich
- Alina G Platonova
- Alina Kerimkulova
- Aline Meirhaeghe
- Aline P Batista
- Alireza Ansari-Moghaddam
- Alireza Khosravi
- Alireza Moslem
- Alireza Sadjadi
- Alisha N Wade
- Alison J Hayes
- Alison J Price
- Allan G Hill
- Allan Linneberg
- Almaz Sharman
- Altan Onat
- Aluisio Jd Barros
- Alun Evans
- Amalia De Curtis
- Amanda G Thrift
- Amanda J Cross
- Amaneh Shayanrad
- Ambady Ramachandran
- Amelia C Crampin
- Amina Barkat
- Amir Houshang Mehrparvar
- Amirabbas Momenan
- Ana Azevedo
- Ana B Crujeiras
- Ana Barradas-Pires
- Ana Carolina Mgn de Sá
- Ana D González-Alvarez
- Ana Henriques
- Ana I Rito
- Ana Jelaković
- Ana Maria B Menezes
- Ana P Ortiz
- Ana Paula C Cândido
- Anabela Mota-Pinto
- Anar Dushpanova
- Anastasia Markaki
- Anders Grøntved
- Andre L Guimaraes
- Andre P Kengne
- Andrea Gazzinelli
- Andrea Gualtieri
- Andrea Rodriguez-Martinez
- Andrea Rvr Horimoto
- Andrea Schneider
- Andrea Y Rodríguez
- Andrea Zentai
- Andreas Stang
- Andreia N Pizarro
- Andrew Kingston
- Andrew Reynolds
- Andrew Wong
- Andrzej Galbarczyk
- Andrzej Pająk
- Andrzej Więcek
- Anelise Reis Gaya
- Aneta Grajda
- Aneta Weres
- Anette Varbo
- Angel R Gonzalez
- Angela Chetrit
- Angela Döring
- Angela Spinelli
- Angelika Schaffrath Rosario
- Angelique Chan
- Angélica M Ochoa-Avilés
- Anie Marcil
- Anil Poudyal
- Anja L Madsen
- Anja Schienkiewitz
- Anna Bartosiewicz
- Anna Bugge
- Anna Fijalkowska
- Anna Jansson
- Anna V Alieva
- Annamari Lundqvist
- Anne A Bjerregaard
- Anne Chinnock
- Anne Juolevi
- Anne Taylor
- Anne Tjonneland
- Anneke Blokstra
- Annette J Dobson
- Annette Peters
- Annika Rosengren
- Anthony Kafatos
- Antonia Trichopoulou
- Antonio Bernabe-Ortiz
- Antonio Cabrera de León
- Antonio M Silva
- Antonio Mistretta
- Antonio Pedro Graça
- Antonio Prista
- Antonis Zampelas
- Antonisamy Belavendra
- Anu Mishra
- Anwar M Batieha
- Archie W Rayner
- Areti Triantafyllou
- Argyro Karakosta
- Ari Voutilainen
- Aristides M Machado-Rodrigues
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- Valéria Regecová
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- Valter Barbosa Filho
- Vanessa Rouzier
- Vanina Bongard
- Vasiliki Efthymiou
- Vassilis Zafiropulos
- Vayia Rarra
- Vedrana Sember
- Veikko Salomaa
- Vera Lanska
- Vera Musil
- Veronica Mocanu
- Vesna Juresa
- Vesselka L Duleva
- Victor M Herrera
- Victor Matsudo
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- Vijaya Lingam
- Viktoria Anna Kovacs
- Viktoriya Furdela
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- Violeta Iotova
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- Viswanathan Mohan
- Viviana Guajardo
- Viviane C Cardoso
- Vladimir Kutsenko
- Wafaie W Fawzi
- Wan Mohamad Wan Bebakar
- Wan Nazaimoon Wan Mohamud
- Wei Zheng
- Wei-Cheng Lo
- Wei-Yen Lim
- Weili Yan
- Wen-Harn Pan
- Wenbin Wei
- Wendy Van Lippevelde
- Wenhua Zhao
- Wichai Aekplakorn
- Willem A Hanekom
- William A Neal
- William R Tebar
- Wilma M Hopman
- Winsome R Parnell
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- Wojciech Drygas
- Wojciech Rusek
- Wolfgang Ahrens
- Wolfgang Kratzer
- Xenophon Theodoridis
- Xiangjun Wang
- Xiaoguang Yang
- Xiaotian Liu
- Ximena Berrios Carrasola
- Xinyi Gwee
- Xiu-Hua Guo
- Xu Lin
- Xu Ma
- Xueling Sim
- Xun Tang
- Ya Xing Wang
- Yadlapalli S Kusuma
- Yajaira Briceño
- Yang Yang
- Yanhui Dong
- Yanina Zocalo
- Yanitsa V Zhecheva
- Yannis Manios
- Yanping Li
- Yemane Berhane
- Yeunsook Rho
- Yeva Movsesyan
- Yi Song
- Yi Zeng
- Yih Chung Tham
- Yiling J Cheng
- Yin Guo
- Ying-Wei Wang
- Yingfeng Zheng
- Yn-Tz Sung
- Yong Tao
- Yonghua Hu
- Yosef Farzi
- Yoto Yotov
- Youcef Laid
- Young-Ho Khang
- Yousef Saleh Khader
- Yu-Ling Yu
- Yuan He
- Yufang Bi
- Yuki Fujita
- Yulia Balanova
- Yuliya V Solovieva
- Yuna He
- Yunjiang Yu
- Yury P Nikitin
- Yves Kameli
- Yves Martin-Prevel
- Yvonne T van der Schouw
- Zahra Mohammadi
- Zbigniew Gaciong
- Zbigniew Kulaga
- Zengchang Pang
- Zhamilya Battakova
- Zhamyila Usupova
- Zhanna Kalmatayeva
- Zhen-Yu Zhang
- Zhengming Chen
- Ziad A Abdeen
- Zivka Dika
- Zlatko Fras
- Zulfiqar A Bhutta
- Zulfiya Abdurrahmonova
- Zumin Shi
- Łukasz Kryst
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We
estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from
1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods We used data from 3663 population-based studies with 222 million participants that measured height and
weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate
trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children
and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the
individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference)
and obesity (BMI >2 SD above the median).
Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in
11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed
changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and
140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of
underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and
countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior
probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse
was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of
thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a
posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%)
with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and
obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for
both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such
as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged
children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls
in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and
42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents,
the increases in double burden were driven by increases in obesity, and decreases in double burden by declining
underweight or thinness.
Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an
increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy
nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of
underweight while curbing and reversing the increase in obesit
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19
- Author
- ?ivko Iris
- Abbass Hakam
- Abdeladim Lilia
- Abdelhady Hesham
- Abdelkharim Hussam
- Abdelrazik Marwa
- Abdi Zakee
- Abdukahil Sheryl Ann
- Abel Lynn
- Abraham Jacinta
- Abrahamson Gail
- Abusamra Yousuf
- Aceto Romina
- Adams Nick
- Adams Peter
- Adebambo Olumide
- Adhikari Neill
- Adhikari Sheetal
- Affleck Julia
- Agha Gloria
- Aghemo Alessio
- Agno Ronan
- Ahmad Norfaizan
- Ain Quratul
- Ainscough Kate
- Ainsworth James
- Aitken Lindianne
- Akamp Ceren
- Al Enezi Farhan
- Al-Bassam Wisam
- Al-Beidh Farah
- Albert Martin
- Albrett Jonathan
- Alderman Meera
- Aldo Bonizzoni Matteo
- Alegria Ana
- Alessandro Carà Gianmarco
- Alexander Brian
- Alexander Peter
- Alfonso Jordan
- Ali Maryam
- Ali Murtaza
- Allam Hayat
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- Allen Louise
- Allibone Suzanne
- Almeshhedani Hasham
- AlQahtani Samah
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- Altomy Mohammed
- Al Amri Ali
- Al Qasim Eman
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- Ambrosino Richard
- Anderson Thomas
- Andreae Mark
- Aneman Anders
- Angus Derek C.
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Anne-Laure Fedou
- Anstey Matthew
- Antcliffe David
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- Antoine Marchalot
- Antoine Pierre
- Antoine Studer
- Anumakonda Vikram
- Aparicio Christelle
- Aquino Maia
- Arabi Yaseen M.
- Arachchige Malka
- Aravindan Latha
- Arbane Gill
- Archambault Patrick
- Archer Simon
- Aref Noah
- Arias Ana-Marie
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- Bongaerts Katherine
- Bonner Stephen
- Bonten Marc J. M.
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- Bracke Stephanie
- Bradbury Charlotte A.
- Bradley Paul
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- Brasselet Aurélie
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- Bridges Sarah
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- Brittain Michael
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- Brochard Laurent
- Brodbeck Andreas
- Brohi Farooq
- Brooks Nicole
- Brown Cynthia
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- Brown Nerissa
- Brown Zarah
- Brugman Curt
- Brunetta Enrico
- Brunkhorst Frank M.
- Brunskill Nigel
- Bryan-Morris Kayla
- Bryden Emma
- Budd Joanna
- Buehner Ulrike
- Buhay Megan
- Buhr Heidi
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- Carmichael Samantha
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- Catorze Nuno José Teodoro Amaro dos Santos
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- Charlton Sam
- Charron Cyril
- Chartier Delphine
- Chasse Michael
- Chassé Michaël
- Chen Jonathan
- Chen Lixian
- Chen Yan
- Cheng Allen C.
- Cherian Shiney
- Chhablani Manish
- Chin Teri
- Chudeau Nicolas
- Chukkambotla Sri
- Ciccarelli Michele
- Cirstea Emanuel
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- Cook Tim
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- Cooke Justin
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- Davies Michelle
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- Day Christopher
- Da Rocha Joana
- De Bus Liesbet
- de Courcy-Golder Kim
- de Groot Klaas
- de Jong Menno
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- De Keulenaer Bart
- de la Torre Cisneros Julian
- de Man Angelique
- De Neef Mark
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- Denham Lynn
- Denmade Craig
- Dent Martin
- Depante Maria
- Depuydt Pieter
- Dequin Pierre-François
- Derde Lennie P. G.
- Deshpande Kush
- Detry Michelle A.
- Deye Nicolas
- de la Fuente Carmen
- De Waele Jan
- Dheke Krishan
- Di Lucca Giuseppe
- Dias Priya
- Dice Julie
- Digby Stephen
- Diridis Kristina
- Distler Michael
- Dobell-Brown Kelsey
- Doble Patricia
- Dobson Jade
- Doherty Kaleigh
- Doherty Ronan
- Doi Yohei
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- Domingo-Marco Joana
- Donadee Chenell
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- Douillard Thomas
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- Ebenezer R
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- Edwards Alexandra
- Efford Georgia
- Egreteau Pierre
- Ehrmann Stephan
- Eichenauer Dennis
- Eisenbeis Simone
- Ekhérian Jean-Michel
- El-Khawas Khaled
- Elender Corinna
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- Englert Sarah
- English Shane
- Epelman¸ Slava
- Eroglu Ege
- Estcourt Lise J.
- Estensen Kristen
- Evans Amy
- Evans Andrew
- Evans Debra
- Evans Gabrielle
- Everitt Robert
- Evers Mirjam
- Evetts George
- Ewalds Esther
- Ezekowitz Justin
- Fagan Laura
- Fagbodun Elizabeth
- Farahi Neda
- Fareed Komal
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- Fartoukh Muriel
- Faulkner Beverley
- Faulkner Maria
- Fazla Fathima
- Featherstone Peter
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- Ferguson Susan
- Fergusson Dean
- Fernandes Edna
- Fernandez Maria
- Fernando Gloria
- Fernández de Pinedo Artaraz Ziortza
- Ferreira Ricardo Manuel Castro
- Ferrier Janet
- Ferringer Cindy
- Fesz Jessica
- Fierens Jan
- Finch Cheryl
- Finn André
- Finn Stephanie
- Finnis Mackenzie
- Fiouni Sofia
- Fischer Roy
- Fitzgerald Mark
- Fitzpatrick Meghan
- Fletcher Simon
- Flint Neil
- Flor Thomas
- Florescu Simin
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- Flynn Gordon
- Focà Emanuele
- Folci Marco
- Forbes Andrew
- Ford Megan
- Forster Elliot
- Foster Tracy
- Fottrell-Gould Deirdre
- Foulds Angela
- Fowler Rob
- Fowler Robert
- Fox Claire
- Fox Eleonore
- Fragner Gertrud
- Frakking Thuy
- Franch-LLasat Diego
- Francis Olesya
- Francoeur François
- Francois Bruno
- Frankfurter Claudia
- Franz Christopher
- François Bourgerol
- Fraser Catherine
- Frater Alasdair
- French Craig
- Frey Anna
- Frey Christian
- Frise Matthew
- Frost Victoria
- Fuchs Ralph
- Fujitani Shigeki
- Fysh Ed
- Gachet Alexandre
- Galbiati Carola
- Galea James
- Ganesan Arunkumar
- Ganesan Manisha
- Ganguly Saibal
- Garcia Sara
- Gardiner-Hill Caroline
- Garot Denis
- Garrard Hywel
- Garrard William
- Garrett Peter
- Garrier Ludivine
- Garrod Esther
- Garton Mark
- Garvey James
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- Gattas David
- Gauli Basanta
- Gay Alexandra
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- Gemmell Lisa
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- Geng Wenli
- Geoghegan Pierce
- Geri Guillaume
- Geurts Heidi
- Ghaffari Mehrdad
- Ghamraoui Ali
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- Ghosh Alison
- Giardina Giuseppe
- Gibbins Alexandra
- Gill Mandy
- Gilliam Matthew
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- Gladas Kirsty
- Glasby Kathleen
- Gledhill Lisa
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- Glynou Loukia
- Goddard Wendy
- Godement Mathieu
- Godoy Lucas C.
- Goebeler M.E.
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- Goldman John
- Goligher Ewan
- Gomez Keith
- Gommans Frank
- Goodwin Jayne
- Goossens Herman
- Gopal Shameer
- Gopinath Amitha
- Goralski Patricia
- Gordon Anthony C.
- Gosbell Iain
- Gould Richard
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- Graham Cheryl
- Graham Libby
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- Greene Emma
- Greener Danni
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- Gummadi Mahitha
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- Gurung Anita
- Guérin Emmanuelle
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- Göpel Siri
- Habeichi Wadih
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- Haider Nafeesah
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- Hajdu Bence
- Hakak Sheeba
- Halden Sandra
- Haldeos Anne
- Hall Alistair S
- Hall Amelia
- Hall Andrew
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- Hall Rebecca
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- Hand James
- Haniffa Rashan
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- Harris Jade
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- Harrison David A.
- Harrison Susan
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- Hernandez Erik
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- Hey Samuel
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- Hierons Sarah
- Higgins Alisa M.
- Hill Claire
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- Hornsby James
- Horton Michelle
- Horvat Christopher M.
- Howcroft Clare
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- Howle Ryan
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- Huang David T.
- Hughes Debbie
- Hugill Keith
- Huijbens Danique
- Hullegie Sebastiaan
- Hulley Amanda
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- Hulse Sarah
- Humphrey Charlotte
- Hunt Beverley
- Hunter Stephanie
- Hurford Sally-Anne
- Hussain Mahwish
- Hussain Sajid
- Hutchinson Christina
- Hutton Paula
- Hüning Vanessa
- Ichihara Nao
- Ijaz Nazia
- Ikhena Ikhuemose
- Inskip Deborah
- Irving Ben
- Isgro Graziella
- Isguzar Agah
- Ishani Pramodya
- Ivatt Helen
- Jackson Carolyn
- Jackson Shane
- Jackson Susan
- Jacob Reni
- Jacquier Sophie
- Jafarzadeh Mina
- Jagannathan Vijay
- Jain Susan
- James Augustian
- James Christie
- Jan Hassing Robert
- Janin Pierre
- Jarczak Dominik
- Jarman Claire
- Jayakumar Deva
- Jayakumar Devachandran
- Jean-Pierre Eraldi
- Jeblaoui Asma
- Jenkins Samuel
- Jenkins Sarah
- Jenkins Steve
- Jennings Stacey
- Jepson Eleanor
- Jerenec Katja
- Jesty Robert
- Jha Avinash
- Jha Rajeev
- Jhanji Shaman
- Jin Xia
- Jindai Kazuaki
- John Maya
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- Johnson Paul
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- Johnson Toby
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- Jones Andrea
- Jones Cathy
- Jones Dawn
- Jones Emily
- Jones Jessica
- Jones Samantha
- Jongebloed Katherine
- Joseph Sibet
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- Joyce Kirsten
- Juffermans Nicole
- Juhaz Vera
- Kadam Umesh
- Kalamar ?iga
- Kalchko-Veyssal Selver
- Kalchthaler Kyle
- Kaliappan Agilan
- Kalla Ismail
- Kalogirou Michael
- Kamata Kazuhiro
- Kamel Toufik
- Kampschreur Linda
- Kamra Maneesha
- Kandeepan Revathi
- Kannan Santhana
- Kannan Thogulava
- Kanwal Darakhshan
- Karachi Tim
- Karim Hina
- Karki Rakshya
- Karlikowski Michal
- Karlsson Sari
- Kasipandian Vidya
- Kassir Sandy
- Katary Amro
- Kato Hideaki
- Kavanagh Lisa
- Kayani Abdul
- Kayastha Srijana
- Kaye Callum
- Kazi Aayesha
- KC Shirish
- KC Shirsh
- Keating Liza
- Keatley Claire
- Keeler Sheryl
- Keen Alexandra
- Keen Sherbrina
- Keijzer-Timmers Nicole
- Kell Kay
- Kelly Martin
- Kelly Niamh
- Kelsall Olivia
- Kendrick Sara
- Kernan Maeve
- Kerslake Ian
- Kester Esmee
- Khade Reena
- Khalid Imrana
- Khan Meherunnisa
- Khanal Kishor
- Khanal Sushil
- Khare Divya
- Khoso Nasir
- Khoud Ahmed
- Khwaja Kosar
- Kidwai Aneela
- Kiiski Heikki
- Kilner Mari
- Kim Edy Y.
- Kimpton Sarah
- King Andrew
- Kinney Fiona
- Kirk Jill
- Kirk Rosemary
- Kirkby Amy
- Kirkham Simon
- Kit Barbara
- Kitsios Georgios
- Kittridge Lauren
- Klein Daniela
- Klop-Riehl Margreet
- Kluge Stefan
- Knowles Karen
- Kochanek Matthias
- Kochert Erik
- Koelink Maaike
- Koirala Kanchan
- Koirala Sabin
- Kolanos Steffi
- Kolovou Angeliki
- Konecny Pam
- Kong Jing
- Koopmans Matty
- Kosa Alma
- Kremling Julius
- Kreß Gabriele
- Krishnamoorthy S
- Krishnamurthy Vinodh
- Kruger Peter
- Kruisdijk-Gerritsen Arriette
- Kruisselbrink Rebecca
- Kuitunen Anne
- Kumar Anand
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- Kumar Rohit
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- Lampro Lamprini
- Landais Michaël
- Landoni Giovanni
- Landsiedel-Mechenbier Elke
- Lang Eva
- Langridge Emma
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- Yu Haili
- Yusuff Hakeem
- Zaharia Mihaela
- Zaidi Abbas
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- Zaman Mohsin
- Zarychanski Ryan
- Zdanavidiene Ausra
- Zhao Xiao
- Zinzoni Vanessa
- Zitter Letizia
- Zouita Louisa
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 11/04/2023
- Field of study
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19.
DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022).
INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days.
MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes.
RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively).
CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes.
TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570
“Sight” Words and the Disabled Reader
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Interpreting the Trail Making Test Following Traumatic Brain Injury: Comparison of Traditional Time Scores and Derived Indices
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Problems of the Internationalization of the Practice of Law (in French) (La Problématique de L'internationalisation de L'exercice du Droit)
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- Guessous Idris
- Guimaraes Andre L.
- Gulliford Martin C.
- Gunnlaugsdottir Johanna
- Gunter Marc J.
- Guo Xiu-Hua
- Guo Yin
- Gupta Prakash C.
- Gupta Rajeev
- Gureje Oye
- Gutierrez Laura
- Gutzwiller Felix
- Gwee Xinyi
- Gómez Georgina
- Gómez Jesús Humberto Gómez
- Gómez Santiago F.
- Ha Seongjun
- Hadaegh Farzad
- Hadjigeorgiou Charalambos A.
- Haghshenas Rosa
- Hakimi Hamid
- Halkjær Jytte
- Hambleton Ian R.
- Hamzeh Behrooz
- Hanekom Willem A.
- Hange Dominique
- Hanif Abu A. M.
- Hantunen Sari
- Hao Jie
- Hardman Carla Menêses
- Harooni Javad
- Hashemi-Shahri Seyed Mohammad
- Hassapidou Maria
- Hata Jun
- Haugsgjerd Teresa
- Hayes Alison J.
- He Jiang
- He Yuan
- He Yuna
- Heidinger-Felső Regina
- Heier Margit
- Heinen Mirjam
- Hejgaard Tatjana
- Hendriks Marleen Elisabeth
- Henriques Ana
- Herrala Sauli
- Herrera Victor M.
- Herrera-Cuenca Marianella
- Herter-Aeberli Isabelle
- Herzig Karl-Heinz
- Heshmat Ramin
- Hill Allan G.
- Ho Sai Yin
- Ho Suzanne C.
- Hobbs Michael
- Holdsworth Michelle
- Homayounfar Reza
- Homs Clara
- Hopman Wilma M.
- Horimoto Andrea R. V. R.
- Hormiga Claudia M.
- Horta Bernardo L.
- Houti Leila
- Howitt Christina
- Htay Thein Thein
- Htet Aung Soe
- Htike Maung Maung Than
- Hu Yonghua
- Huerta José María
- Huhtaniemi Ilpo Tapani
- Huiart Laetitia
- Huisman Martijn
- Husseini Abdullatif
- Huu Chinh Nguyen
- Huybrechts Inge
- Hwalla Nahla
- Hyska Jolanda
- Höfelmann Doroteia A.
- Iacoviello Licia
- Iakupova Ellina M.
- Ibarluzea Jesús M.
- Ibrahim Mohsen M.
- Ikeda Nayu
- Ikram M. Arfan
- Ioannidou Eliza Markidou
- Iotova Violeta
- Irazola Vilma E.
- Ishida Takafumi
- Isiguzo Godsent C.
- Islam Muhammad
- Islam Sheikh Mohammed Shariful
- Islek Duygu
- Iurilli Maria L. C.
- Ivanova-Pandourska Ivaila Y.
- Iwasaki Masanori
- Iñiguez Carmen
- Jackson Rod T.
- Jacobs Jeremy M.
- Jadoul Michel
- Jafar Tazeen
- Jallow Bakary
- James Kenneth
- Jamil Kazi M.
- Jamrozik Konrad
- Jansson Anna
- Janszky Imre
- Janus Edward
- Jarani Juel
- Jarvelin Marjo-Riitta
- Jasienska Grazyna
- Jelaković Ana
- Jelaković Bojan
- Jennings Garry
- Jiang Chao Qiang
- Jimenez Maritza Landaeta
- Jimenez Ramon O.
- Joffres Michel
- Jokelainen Jari J.
- Jonas Jost B.
- Jonnagaddala Jitendra
- Jonsson Kenisha Russell
- Joshi Pradeep
- Josipović Josipa
- Joukar Farahnaz
- Judge Debra S.
- Juolevi Anne
- Jurak Gregor
- Juresa Vesna
- Jääskeläinen Tuija
- Jérome Charles Sossa
- Jóźwiak Jacek J.
- Jöckel Karl-Heinz
- Jørgensen Maja Bæksgaard
- Jørgensen Torben
- Kaaks Rudolf
- Kaducu Felix O.
- Kafatos Anthony
- Kaj Mónika
- Kajantie Eero O.
- Kakutia Natia
- Kalmatayeva Zhanna
- Kalter-Leibovici Ofra
- Kameli Yves
- Kampmann Freja B.
- Kanala Kodanda R.
- Kannan Srinivasan
- Kapantais Efthymios
- Karaglani Eva
- Karakosta Argyro
- Karki Khem B.
- Katchunga Philippe B.
- Katibeh Marzieh
- Katz Joanne
- Katzmarzyk Peter T.
- Kauhanen Jussi
- Kaur Prabhdeep
- Kavousi Maryam
- Kazakbaeva Gyulli M.
- Kaze François F.
- Ke Calvin
- Keil Ulrich
- Keinänen-Kiukaanniemi Sirkka
- Kelishadi Roya
- Kelleher Cecily
- Kemper Han C. G.
- Kengne Andre P.
- Keramati Maryam
- Kerimkulova Alina
- Kersting Mathilde
- Key Timothy
- Khader Yousef Saleh
- Khaledifar Arsalan
- Khalili Davood
- Khang Young-Ho
- Khaw Kay-Tee
- Kheiri Bahareh
- Kheradmand Motahareh
- Khosravi Alireza
- Khouw Ilse M. S. L.
- Kiechl Sophia J.
- Kiechl Stefan
- Kiechl-Kohlendorfer Ursula
- Killewo Japhet
- Kim Hyeon Chang
- Kim Jeongseon
- Kindblom Jenny M.
- Kingston Andrew
- Klakk Heidi
- Klimek Magdalena
- Klimont Jeannette
- Klumbiene Jurate
- Knoflach Michael
- Koirala Bhawesh
- Kolle Elin
- Kolsteren Patrick
- Korpelainen Raija
- Korrovits Paul
- Korzycka Magdalena
- Kos Jelena
- Koskinen Seppo
- Kouda Katsuyasu
- Kovacs Viktoria Anna
- Kovalskys Irina
- Kovtun Olga Petrovna
- Kovács Éva
- Kowlessur Sudhir
- Koziel Slawomir
- Kratenova Jana
- Kratzer Wolfgang
- Kriaucioniene Vilma
- Kriemler Susi
- Kristensen Peter Lund
- Krizan Helena
- Kroker-Lobos Maria F.
- Krokstad Steinar
- Kromhout Daan
- Kruger Herculina S.
- Kruger Ruan
- Kryst Łukasz
- Kubinova Ruzena
- Kuciene Renata
- Kujala Urho M.
- Kujundzic Enisa
- Kulaga Zbigniew
- Kulimbet Mukhtar
- Kumar R. Krishna
- Kumar Rachakulla Hari
- Kunešová Marie
- Kurjata Pawel
- Kusuma Yadlapalli S.
- Kutsenko Vladimir
- Kuulasmaa Kari
- Kyobutungi Catherine
- Kállayová Daniela
- Kårhus Line L.
- König Jürgen
- La Quang Ngoc
- Laamiri Fatima Zahra
- Laatikainen Tiina
- Lachat Carl
- Lackner Karl J.
- Laid Youcef
- Lall Lachmie
- Lam Tai Hing
- Landais Edwige
- Lanska Vera
- Lappas Georg
- Larijani Bagher
- Larissa Simo Pone
- Lassen Tina Harmer
- Latt Tint Swe
- Laurenzi Martino
- Lauria Laura
- Laxmaiah Avula
- Lazo-Porras Maria
- Le Coroller Gwenaëlle
- Le Nguyen Bao Khanh
- Le Port Agnès
- Le Tuyen D.
- Lee Jeannette
- Lee Jeonghee
- Lee Paul H.
- Lehmann Nils
- Lehtimäki Terho
- Lele Elysée Claude Bika
- Lemogoum Daniel
- Leskošek Branimir
- Leszczak Justyna
- Leth-Møller Katja B.
- Leung Gabriel M.
- Levitt Naomi S.
- Lhoste Victor
- Li Yanping
- Liivak Merike
- Lilly Christa L.
- Lim Charlie
- Lim Wei-Yen
- Lima-Costa M. Fernanda
- Lin Hsien-Ho
- Lin Xu
- Lin Yi-Ting
- Lind Lars
- Lingam Vijaya
- Linkohr Birgit
- Linneberg Allan
- Lissner Lauren
- Litwin Mieczyslaw
- Liu Jing
- Liu Lijuan
- Lo Wei-Cheng
- Loit Helle-Mai
- Long Khuong Quynh
- Lopes Luis
- Lopes Marcus V. V.
- Lopes Oscar
- Lopez Tania
- Lopez-Garcia Esther
- Lotufo Paulo A.
- Lozano José Eugenio
- Lukrafka Janice L.
- Luksiene Dalia
- Lundqvist Annamari
- Lunet Nuno
- Lunogelo Charles
- Lustigová Michala
- Ma Guansheng
- Ma Jun
- Ma Xu
- Machado-Coelho George L. L.
- Machado-Rodrigues Aristides M.
- Macia Enguerran
- Macieira Luisa M.
- Madar Ahmed A.
- Madsen Anja L.
- Maestre Gladys E.
- Maggi Stefania
- Magliano Dianna J.
- Magnacca Sara
- Magnazu Moran Blychfeld
- Magriplis Emmanuella
- Mahasampath Gowri
- Maire Bernard
- Majer Marjeta
- Makdisse Marcia
- Malekzadeh Fatemeh
- Malekzadeh Reza
- Malhotra Rahul
- Malyutina Sofia K.
- Maniego Lynell V.
- Manios Yannis
- Manix Masimango Imani
- Mann Jim I.
- Mansour-Ghanaei Fariborz
- Manyanga Taru
- Manzato Enzo
- Marcil Anie
- Margozzini Paula
- Marina Loreto Santa
- Mariño Joany
- Markaki Anastasia
- Markey Oonagh
- Marques Larissa Pruner
- Marques-Vidal Pedro
- Marrugat Jaume
- Martin Rosemarie
- Martin-Prevel Yves
- Martinez Eduardo Salazar
- Martorell Reynaldo
- Martos Eva
- Maruszczak Katharina
- Marventano Stefano
- Masala Giovanna
- Mascarenhas Luis P.
- Masoodi Shariq R.
- Mathiesen Ellisiv B.
- Mathur Prashant
- Matijasevich Alicia
- Matsha Tandi E.
- Matsudo Victor
- Matłosz Piotr
- Mavrogianni Christina
- Mazur Artur
- Mbanya Jean Claude N.
- McFarlane Shelly R.
- McGarvey Stephen T.
- McKee Martin
- McLachlan Stela
- McLean Rachael M.
- McLean Scott B.
- McNairy Margaret L.
- McNulty Breige A.
- Medzioniene Jurate
- Mehdipour Parinaz
- Mehlig Kirsten
- Mehrparvar Amir Houshang
- Meirhaeghe Aline
- Meisfjord Jørgen
- Meisinger Christa
- Melgarejo Jesus D.
- Melkumova Marina
- Mello João
- Mendivil Carlos O.
- Menezes Ana Maria B.
- Menon Geetha R.
- Mensink Gert B. M.
- Menzano Maria Teresa
- Meshram Indrapal I.
- Meto Diane T.
- Mi Jie
- Michaelsen Kim F.
- Michels Nathalie
- Mikkel Kairit
- Milanović Sanja Musić
- Miller Jody C.
- Milushkina Olga
- Minderico Cláudia S.
- Mini G. K.
- Miquel Juan Francisco
- Miranda J. Jaime
- Mirjalili Mohammad Reza
- Mirkopoulou Daphne
- Mirrakhimov Erkin
- Mishra Anu
- Mistretta Antonio
- Miłkowska Karolina
- Mišigoj-Duraković Marjeta
- Mocanu Veronica
- Modesti Pietro A.
- Moghaddam Sahar Saeedi
- Mohajer Bahram
- Mohamed Mostafa K.
- Mohamed Shukri F.
- Mohammad Kazem
- Mohammadi Mohammad Reza
- Mohammadi Zahra
- Mohammadifard Noushin
- Mohammadpourhodki Reza
- Mohamud Wan Nazaimoon Wan
- Mohan Viswanathan
- Mohanna Salim
- Mohebbi Iraj
- Mohebi Farnam
- Moitry Marie
- Molnár Dénes
- Momenan Amirabbas
- Mondo Charles K.
- Monroy-Valle Michele
- Montenegro Mendoza Roger A.
- Monterrubio-Flores Eric
- Monyeki Kotsedi Daniel K.
- Moon Jin Soo
- Moosazadeh Mahmood
- Mopa Hermine T.
- Moradpour Farhad
- Moreira Leila B.
- Morejon Alain
- Moreno Emma Ruiz
- Moreno Luis A.
- Morey Francis
- Morgan Karen
- Morin Suzanne N.
- Mortensen Erik Lykke
- Moschonis George
- Moslem Alireza
- Mossakowska Malgorzata
- Mostafa Aya
- Mostafavi Seyed-Ali
- Mota Jorge
- Mota-Pinto Anabela
- Motlagh Mohammad Esmaeel
- Motta Jorge
- Moura-dos-Santos Marcos André
- Movsesyan Yeva
- Mridha Malay K.
- Msyamboza Kelias P.
- Mu Thet Thet
- Muc Magdalena
- Muca Florian
- Mugoša Boban
- Muiesan Maria L.
- Mursu Jaakko
- Murtagh Elaine M.
- Musa Kamarul Imran
- Musil Vera
- Musinguzi Geofrey
- Muyer Muel Telo M. C.
- Mäki Päivi
- Méndez Fabián
- Mérida María José García
- Møllehave Line T.
- Møller Niels C.
- Müller-Nurasyid Martina
- Münzel Thomas
- M’Buyamba-Kabangu Jean-René
- Nabipour Iraj
- Naderimagham Shohreh
- Nagel Gabriele
- Najafi Farid
- Nakamura Harunobu
- Nalecz Hanna
- Nang Ei Ei K.
- Nangia Vinay B.
- Nankap Martin
- Narake Sameer
- Nardone Paola
- Naseri Take
- Nauck Matthias
- NCD Risk Factor Collaboration (NCD-RisC) [missing]
- Neal William A.
- Nejatizadeh Azim
- Nekkantti Chandini
- Nelis Keiu
- Nenko Ilona
- Neovius Martin
- Nervi Flavio
- Ng Tze Pin
- Nguyen Chung T.
- Nguyen Nguyen D.
- Nguyen Quang Ngoc
- Ni Michael Y.
- Nicolescu Rodica
- Nie Peng
- Nieto-Martínez Ramfis E.
- Nikitin Yury P.
- Ning Guang
- Ninomiya Toshiharu
- Nishi Nobuo
- Nishtar Sania
- Noale Marianna
- Noboa Oscar A.
- Nogueira Helena
- Nordendahl Maria
- Nordestgaard Børge G.
- Noto Davide
- Nowak-Szczepanska Natalia
- Nsour Mohannad Al
- Nuhoğlu Irfan
- Nunes Baltazar
- Nurk Eha
- Nuwaha Fred
- Nyirenda Moffat
- Námešná Jana
- Obreja Galina
- Ochimana Caleb
- Ochoa-Avilés Angélica M.
- Oda Eiji
- Odili Augustine N.
- Oh Kyungwon
- Ohara Kumiko
- Ohlsson Claes
- Ohtsuka Ryutaro
- Olafsson Örn
- Olinto Maria Teresa A.
- Oliveira Isabel O.
- Omar Mohd Azahadi
- Omar Saeed M.
- Onat Altan
- Ong Sok King
- Onland-Moret N. Charlotte
- Ono Lariane M.
- Ordunez Pedro
- Ornelas Rui
- Ortiz Ana P.
- Ortiz Pedro J.
- Osler Merete
- Osmond Clive
- Ostojic Sergej M.
- Ostovar Afshin
- Otero Johanna A.
- Overvad Kim
- Owusu-Dabo Ellis
- O’Neill Terence W.
- O’Reilly Dermot
- Paccaud Fred Michel
- Paciorek Christopher J.
- Padez Cristina P.
- Pagkalos Ioannis
- Pahomova Elena
- Pająk Andrzej
- Palloni Alberto
- Palmieri Luigi
- Pan Wen-Harn
- Panda-Jonas Songhomitra
- Pandey Arvind
- Panza Francesco
- Paoli Mariela
- Papadopoulou Sousana K.
- Papandreou Dimitrios
- Pareja Rossina G.
- Park Soon-Woo
- Park Suyeon
- Parnell Winsome R.
- Parsaeian Mahboubeh
- Pascanu Ionela M.
- Pasquet Patrick
- Patel Nikhil D.
- Pattussi Marcos
- Pavlyshyn Halyna
- Pechlaner Raimund
- Pednekar Mangesh S.
- Pedro João M.
- Peer Nasheeta
- Peixoto Sergio Viana
- Peltonen Markku
- Pereira Alexandre C.
- Peres Marco A.
- Peterkova Valentina
- Peters Annette
- Petersmann Astrid
- Petkeviciene Janina
- Petrauskiene Ausra
- Petrescu Constanta Huidumac
- Pettenuzzo Emanuela
- Peykari Niloofar
- Pećin Ivan
- Pfeiffer Norbert
- Phall Modou Cheyassin
- Pham Son Thai
- Phelps Nowell H.
- Pichardo Rafael N.
- Pierannunzio Daniela
- Pigeot Iris
- Pikhart Hynek
- Pilav Aida
- Pilotto Lorenza
- Pistelli Francesco
- Pitakaka Freda
- Piwonska Aleksandra
- Pizarro Andreia N.
- Plans-Rubió Pedro
- Platonova Alina G.
- Poh Bee Koon
- Pohlabeln Hermann
- Polka Nadija S.
- Pop Raluca M.
- Popovic Stevo R.
- Porta Miquel
- Posch Georg
- Poudyal Anil
- Poulimeneas Dimitrios
- Pouraram Hamed
- Pourfarzi Farhad
- Pourshams Akram
- Poustchi Hossein
- Pradeepa Rajendra
- Price Alison J.
- Price Jacqueline F.
- Prista Antonio
- Providencia Rui
- Puder Jardena J.
- Pudule Iveta
- Puiu Maria
- Punab Margus
- Pérez Cynthia M.
- Qadir Muhammed S.
- Qasrawi Radwan F.
- Qorbani Mostafa
- Quintana Hedley K.
- Quiroga-Padilla Pedro J.
- Rach Stefan
- Radic Ivana
- Radisauskas Ricardas
- Rahim Norsyamlina Che Abdul
- Rahimikazerooni Salar
- Rahman Mahfuzar
- Rahman Mahmudur
- Raitakari Olli
- Raj Manu
- Rajabov Tamerlan
- Rakhmatulloev Sherali
- Rakovac Ivo
- Ramachandran Ambady
- Ramadan Otim P. C.
- Ramires Virgílio V.
- Ramke Jacqueline
- Ramos Elisabete
- Ramos Rafel
- Rampal Lekhraj
- Rampal Sanjay
- Rangelova Lalka S.
- Rao Kodavanti Mallikharjuna
- Rao Sudha Ramachandra
- Rarra Vayia
- Rascon-Pacheco Ramon A.
- Rech Cassiano Ricardo
- Redon Josep
- Reganit Paul Ferdinand M.
- Regecová Valéria
- Renner Jane D. P.
- Repasy Judit A.
- Reuter Cézane P.
- Revilla Luis
- Reynolds Andrew
- Rezaianzadeh Abbas
- Rho Yeunsook
- Ribas-Barba Lourdes
- Ribeiro Robespierre
- Riboli Elio
- Richter Adrian
- Rigo Fernando
- Rigotti Attilio
- Riley Leanne M.
- Rinaldo Natascia
- Rinke de Wit Tobias F.
- Ripollés María Pilar Díez
- Rito Ana I.
- Ritti-Dias Raphael M.
- Rivera Juan A.
- Roa Reina G.
- Robinson Louise
- Robitaille Cynthia
- Roccaldo Romana
- Rodrigues Daniela
- Rodriguez-Martinez Andrea
- Rodríguez Andrea Y.
- Rodríguez Inés Sánchez
- Rodríguez-Artalejo Fernando
- Rodríguez-Villamizar Laura A.
- Roggenbuck Ulla
- Rohloff Peter
- Rohner Fabian
- Rojas-Martinez Rosalba
- Rojroongwasinkul Nipa
- Rolandi Gilda Estela Benitez
- Romaguera Dora
- Romeo Elisabetta L.
- Rosario Angelika Schaffrath
- Rosario Rafaela V.
- Rosengren Annika
- Rouse Ian
- Rouzier Vanessa
- Roy Joel G. R.
- Ruano Maira H.
- Rubinstein Adolfo
- Ruidavets Jean-Bernard
- Ruiz-Betancourt Blanca Sandra
- Ruiz-Castell Maria
- Rusakova Iuliia A.
- Russo Paola
- Rust Petra
- Rutkowski Marcin
- Rühli Frank J.
- Saamel Marge
- Sabanayagam Charumathi
- Sabbaghi Hamideh
- Sacchini Elena
- Sachdev Harshpal S.
- Sadjadi Alireza
- Safarpour Ali Reza
- Safi Sare
- Safiri Saeid
- Saghi Mohammad Hossien
- Saidi Olfa
- Saki Nader
- Salanave Benoit
- Saleva Calogero
- Salmerón Diego
- Salomaa Veikko
- Salonen Jukka T.
- Salvetti Massimo
- Samoutian Margarita
- Sandjaja [missing]
- Sans Susana
- Santacruz Ethel
- Santos Diana A.
- Santos Ina S.
- Santos Lèlita C.
- Santos Maria Paula
- Santos Osvaldo
- Santos Rute
- Santos Tamara R.
- Sant’Angelo Victoria Farrugia
- Saramies Jouko L.
- Sardinha Luis B.
- Sarrafzadegan Nizal
- Sathish Thirunavukkarasu
- Saum Kai-Uwe
- Savin Stefan
- Savva Savvas
- Savy Mathilde
- Sawada Norie
- Sbaraini Mariana
- Scazufca Marcia
- Schaan Beatriz D.
- Schargrodsky Herman
- Schienkiewitz Anja
- Schindler Karin
- Schipf Sabine
- Schmidt Carsten O.
- Schmidt Ida Maria
- Schneider Andrea
- Schnohr Peter
- Schramm Sara
- Schramm Stine
- Schröder Helmut
- Schultsz Constance
- Schulze Matthias B.
- Schutte Aletta E.
- Schöttker Ben
- Sebert Sylvain
- Sedaghattalab Moslem
- Selamat Rusidah
- Sember Vedrana
- Sen Abhijit
- Senbanjo Idowu O.
- Sepanlou Sadaf G.
- Sequera Guillermo
- Serra-Majem Luis
- Servais Jennifer
- Shalnova Svetlana
- Shamah-Levy Teresa
- Shamshirgaran Seyed Morteza
- Shanthirani Coimbatore Subramaniam
- Sharafkhah Maryam
- Sharma Sanjib K.
- Shaw Jonathan E.
- Shayanrad Amaneh
- Shayesteh Ali Akbar
- Sheffer Kate E.
- Shengelia Lela
- Shi Zumin
- Shibuya Kenji
- Shimizu-Furusawa Hana
- Shimony Tal
- Shiri Rahman
- Shrestha Namuna
- Si-Ramlee Khairil
- Siani Alfonso
- Siantar Rosalynn
- Sibai Abla M.
- Sidossis Labros S.
- Silitrari Natalia
- Silva Antonio M.
- Silva Diego Augusto Santos
- Silva Kelly S.
- Sim Xueling
- Simina Iulia Jurca
- Simon Mary
- Simons Judith
- Simons Leon A.
- Singleton Rosie K.
- Sjöberg Agneta
- Sjöström Michael
- Skoblina Natalia A.
- Skodje Gry
- Slazhnyova Tatyana
- Slowikowska-Hilczer Jolanta
- Slusarczyk Przemysław
- Smeeth Liam
- So Hung-Kwan
- Soares Fernanda Cunha
- Sobek Grzegorz
- Sobngwi Eugène
- Sodemann Morten
- Soekatri Moesijanti Y. E.
- Soemantri Agustinus
- Sofat Reecha
- Solano Marta García
- Solfrizzi Vincenzo
- Somi Mohammad Hossein
- Sonestedt Emily
- Song Yi
- Soofi Sajid
- Sophiea Marisa K.
- Sorić Maroje
- Soto-Rojas Victoria E.
- Soumaré Aïcha
- Sousa-Poza Alfonso
- Sovic Slavica
- Sparboe-Nilsen Bente
- Sparrenberger Karen
- Spencer Phoebe R.
- Spinelli Angela
- Spiroski Igor
- Staessen Jan A.
- Stamm Hanspeter
- Starc Gregor
- Staub Kaspar
- Stavreski Bill
- Steene-Johannessen Jostein
- Stehle Peter
- Stein Aryeh D.
- Stergiou George S.
- Stessman Jochanan
- Stevanović Ranko
- Stevens Gretchen A.
- Stieber Jutta
- Stokwiszewski Jakub
- Stoyanova Ekaterina
- Stratton Gareth
- Stronks Karien
- Strufaldi Maria Wany
- Sturua Lela
- Stöckl Doris
- Suka Machi
- Sun Chien-An
- Sun Liang
- Sundström Johan
- Sung Yn-Tz
- Sunyer Jordi
- Suriyawongpaisal Paibul
- Suárez-Medina Ramón
- Sweis Nabil William G.
- Swinburn Boyd A.
- Sy Rody G.
- Sylva René Charles
- Szklo Moyses
- Szponar Lucjan
- Sánchez-Abanto Jose
- Söderberg Stefan
- Sørensen Thorkild I. A.
- Sørgjerd Elin P.
- Tabone Lorraine
- Tai E. Shyong
- Tambalis Konstantinos D.
- Tammesoo Mari-Liis
- Tamosiunas Abdonas
- Tan Eng Joo
- Tang Xun
- Tanrygulyyeva Maya
- Tanser Frank
- Tao Yong
- Tarawneh Mohammed Rasoul
- Tarp Jakob
- Tarqui-Mamani Carolina B.
- Taylor Anne
- Taylor Julie
- Tchibindat Félicité
- Te Velde Saskia
- Tebar William R.
- Tell Grethe S.
- Tello Tania
- Tham Yih Chung
- Thankappan K. R.
- Theobald Holger
- Theodoridis Xenophon
- Thomas Nihal
- Thorand Barbara
- Thuesen Betina H.
- Tichá Ľubica
- Timmermans Erik J.
- Tjandrarini Dwi H.
- Tjonneland Anne
- Tolonen Hanna K.
- Tolstrup Janne S.
- Topbas Murat
- Topór-Mądry Roman
- Torheim Liv Elin
- Tormo María José
- Tornaritis Michael J.
- Torrent Maties
- Torres-Collado Laura
- Toselli Stefania
- Touloumi Giota
- Traissac Pierre
- Tran Thi Tuyet-Hanh
- Tremblay Mark S.
- Triantafyllou Areti
- Trichopoulos Dimitrios
- Trichopoulou Antonia
- Trinh Oanh T. H.
- Trivedi Atul
- Tsao Yu-Hsiang
- Tshepo Lechaba
- Tsigga Maria
- Tsintavis Panagiotis
- Tsugane Shoichiro
- Tuitele John
- Tuliakova Azaliia M.
- Tulloch-Reid Marshall K.
- Tullu Fikru
- Tuomainen Tomi-Pekka
- Tuomilehto Jaakko
- Turley Maria L.
- Twig Gilad
- Tynelius Per
- Tzala Evangelia
- Tzotzas Themistoklis
- Tzourio Christophe
- Ueda Peter
- Ugel Eunice
- Ukoli Flora A. M.
- Ulmer Hanno
- Unal Belgin
- Usupova Zhamyila
- Uusitalo Hannu M. T.
- Uysal Nalan
- Vaitkeviciute Justina
- Valdivia Gonzalo
- Vale Susana
- Valvi Damaskini
- van Dam Rob M.
- van den Born Bert-Jan
- Van der Heyden Johan
- van der Schouw Yvonne T.
- Van Herck Koen
- Van Lippevelde Wendy
- Van Minh Hoang
- Van Schoor Natasja M.
- van Valkengoed Irene G. M.
- Vanderschueren Dirk
- Vanuzzo Diego
- Varbo Anette
- Varela-Moreiras Gregorio
- Vargas Luz Nayibe
- Varona-Pérez Patricia
- Vasan Senthil K.
- Vasques Daniel G.
- Vega Tomas
- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Velika Biruta
- Verloigne Maïté
- Veronesi Giovanni
- Verschuren W. M. Monique
- Victora Cesar G.
- Viegi Giovanni
- Viet Lucie
- Vik Frøydis N.
- Vilar Monica
- Villalpando Salvador
- Vioque Jesus
- Virtanen Jyrki K.
- Visvikis-Siest Sophie
- Viswanathan Bharathi
- Vladulescu Mihaela
- Vlasoff Tiina
- Vocanec Dorja
- Vollenweider Peter
- Voutilainen Ari
- Vrijheid Martine
- Vrijkotte Tanja G. M.
- Vrkic Tajana Zeljkovic
- Völzke Henry
- Wade Alisha N.
- Waldhör Thomas
- Walton Janette
- Wambiya Elvis O. A.
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wareham Nicholas
- Weber Adelheid
- Webster-Kerr Karen
- Wedderkopp Niels
- Weghuber Daniel
- Wei Wenbin
- Weres Aneta
- Werner Bo
- Westbury Leo D.
- Whincup Peter H.
- Wickramasinghe Kremlin
- Widhalm Kurt
- Widyahening Indah S.
- Wild Philipp S.
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Williams Julianne
- Wilsgaard Tom
- Wirth James P.
- Więcek Andrzej
- Wojciech Rusek
- Wojtyniak Bogdan
- Wolf Kathrin
- Wong Andrew
- Wong Emily B.
- Wong Jyh Eiin
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Wu Frederick C.
- Wu Hon-Yen
- Wu Jianfeng
- Wu Li Juan
- Wu Shouling
- Wyszyńska Justyna
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yasuharu Tabara
- Yiallouros Panayiotis K.
- Yngve Agneta
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O.
- Yu Yu-Ling
- Yu Yunjiang
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A.
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilová Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zaw Ko Ko
- Zayed Ayman A.
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhecheva Yanitsa V.
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zoghlami Nada
- Zuziak Monika
- Ängquist Lars
- Čapková Naděžda
- Łuszczki Edyta
- Šalaj Sanja
- Ševčíková Ľudmila
- Żegleń Magdalena
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2023
- Field of study
Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Aarestrup Julie
- Abarca-Gómez Leandra
- Abbasi-Kangevari Mohsen
- Abdeen Ziad A
- Abdrakhmanova Shynar
- Abdul Ghaffar Suhaila
- Abdul Rahim Hanan F
- Abdurrahmonova Zulfiya
- Abu-Rmeileh Niveen M
- Abubakar Garba Jamila
- Acosta-Cazares Benjamin
- Adam Ishag
- Adamczyk Marzena
- Adams Robert J
- Adu-Afarwuah Seth
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agbor Valirie N
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguenaou Hassan
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmadi Nastaran
- Ahmed Imran
- Ahmed Soheir H
- Ahrens Wolfgang
- Aitmurzaeva Gulmira
- Ajlouni Kamel
- Al Asfoor Deena
- Al Hourani Huda M
- Al Qaoud Nawal M
- Al-Hazzaa Hazzaa M
- Al-Hinai Halima
- Al-Lahou Badreya
- Al-Lawati Jawad A
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Aldwairji Maryam A
- Alexius Sylvia
- Ali Mohamed M
- Alieva Anna V
- Alkandari Abdullah
- Alkerwi Ala'a
- Alkhatib Buthaina M
- Allin Kristine
- Alomary Shaker A
- Alomirah Husam F
- Alshangiti Arwa M
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N
- Amiano Etxezarreta Pilar
- Amoah John
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A
- Androutsos Odysseas
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Anufrieva Elena
- Aounallah-Skhiri Hajer
- Araújo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assefa Nega
- Assembekov Batyrbek
- Assunção Maria Cecília F
- Aung May Soe
- Aurélio de Valois Correia Júnior Marco
- Auvinen Juha
- Avdičová Mária
- Avi Shina
- Azad Kishwar
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Ängquist Lars
- Ågren Åsa
- Babu Bontha V
- Bacopoulou Flora
- Baharudin Azli
- Bahijri Suhad
- Bajramovic Izet
- Bakacs Marta
- Baker Jennifer L
- Balakrishna Nagalla
- Balanova Yulia
- Bamoshmoosh Mohamed
- Banach Maciej
- Banegas José R
- Baran Joanna
- Baran Rafał
- Barbagallo Carlo M
- Barbosa Filho Valter
- Barceló Alberto
- Baretić Maja
- Barkat Amina
- Barnoya Joaquin
- Barradas-Pires Ana
- Barrera Lena
- Barreto Marta
- Barros Aluisio JD
- Barros Mauro Virgílio Gomes
- Bartosiewicz Anna
- Basit Abdul
- Bastos Joao Luiz
- Bata Iqbal
- Batieha Anwar M
- Batista Aline P
- Batista Rosangela L
- Battakova Zhamilya
- Baur Louise A
- Bayauli Pascal M
- Beaglehole Robert
- Bel-Serrat Silvia
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benedek Theodora
- Benedics Judith
- Benet Mikhail
- Benitez Rolandi Gilda Estela
- Bennett James E
- Bentham James
- Benzeval Michaela
- Bere Elling
- Berger Nicolas
- Bergh Ingunn Holden
- Berhane Yemane
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Berrios Carrasola Ximena
- Bettiol Heloísa
- Beutel Manfred E
- Beybey Augustin F
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K
- Bhutta Zulfiqar A
- Bi Hongsheng
- Bi Yufang
- Bia Daniel
- Biasch Katia
- Bika Lele Elysée Claude
- Bikbov Mukharram M
- Bista Bihungum
- Bixby Honor
- Bjelica Dusko J
- Bjerregaard Anne A
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B
- Björkelund Cecilia
- Bloch Katia V
- Blokstra Anneke
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- Boehm Bernhard O
- Boer Jolanda MA
- Boggia Jose G
- Bogova Elena
- Boissonnet Carlos P
- Bojesen Stig E
- Bonaccio Marialaura
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Botomba Steve
- Bourne Rupert RA
- Bovet Pascal
- Boymatova Khadichamo
- Braeckevelt Lien
- Braeckman Lutgart
- Bragt Marjolijn CE
- Braithwaite Tasanee
- Brajkovich Imperia
- Branca Francesco
- Breckenkamp Juergen
- Breda João
- Brenner Hermann
- Brewster Lizzy M
- Brian Garry R
- Briceño Yajaira
- Brinduse Lacramioara
- Bringolf-Isler Bettina
- Brito Miguel
- Brophy Sinead
- Brug Johannes
- Bruno Graziella
- Bugge Anna
- Buoncristiano Marta
- Burazeri Genc
- Burns Con
- Bæksgaard Jørgensen Maja
- Cabrera de León Antonio
- Cacciottolo Joseph
- Cai Hui
- Caixeta Roberta B
- Cama Tilema
- Cameron Christine
- Camolas José
- Can Günay
- Cañete Felicia
- Capanzana Mario V
- Capuano Eduardo
- Capuano Rocco
- Capuano Vincenzo
- Cardol Marloes
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- Carlsson Axel C
- Carmuega Esteban
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- Carvalho Joana
- Casajús José A
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- Cervantes-Loaiza Marvin
- Cesar Juraci A
- Chamnan Parinya
- Chamukuttan Snehalatha
- Chan Angelique
- Chan Queenie
- Charchar Fadi J
- Charles Marie-Aline
- Chaturvedi Himanshu K
- Chaturvedi Nish
- Che Abdul Rahim Norsyamlina
- Chee Miao Li
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Long-Sheng
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheng Yiling J
- Cheraghian Bahman
- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chinapaw Mai JM
- Chinnock Anne
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirlaque María-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
- Cinteza Eliza
- Cirillo Massimo
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- Colorado-Yohar Sandra
- Compañ-Gabucio Laura-María
- Concin Hans
- Confortin Susana C
- Cooper Cyrus
- Coppinger Tara C
- Corpeleijn Eva
- Cortés Lilia Yadira
- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J
- Cowell Chris
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- Crampin Amelia C
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- Cruz Juan J
- Csányi Tamás
- Csilla Semánová
- Cucu Alexandra M
- Cui Liufu
- Cureau Felipe V
- Cuschieri Sarah
- Czenczek-Lewandowska Ewelina
- Čapková Naděžda
- D'Arrigo Graziella
- d'Orsi Eleonora
- da Silva Alanna G
- Dacica Liliana
- Dahm Christina C
- Dallongeville Jean
- Damasceno Albertino
- Damsgaard Camilla T
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M
- Dasgupta Parasmani
- Dastgiri Saeed
- Dauchet Luc
- Davletov Kairat
- de Assis Guedes de Vasconcelos Francisco
- de Assis Maria Alice Altenburg
- De Backer Guy
- De Bacquer Dirk
- De Bacquer Jaco
- de Bont Jeroen
- De Curtis Amalia
- de Fragas Hinnig Patrícia
- de Gaetano Giovanni
- De Henauw Stefaan
- De Miguel-Etayo Pilar
- De Neve Jan-Walter
- de Paiva Karina Mary
- De Ridder David
- De Ridder Karin
- de Rooij Susanne R
- de Sá Ana Carolina MGN
- De Smedt Delphine
- Deepa Mohan
- Deev Alexander D
- DeGennaro Vincent Jr
- Delisle Hélène
- Delpeuch Francis
- Demarest Stefaan
- Dennison Elaine
- Dereń Katarzyna
- Deschamps Valérie
- Devrishov Ruslan D
- Dhimal Meghnath
- Di Castelnuovo Augusto
- Di Cesare Mariachiara
- Dias-da-Costa Juvenal Soares
- Diaz Alejandro
- Dika Zivka
- Díaz Fernández Pedro
- Díaz-Sánchez María Elena
- Díez Ripollés María Pilar
- Djalalinia Shirin
- Djordjic Visnja
- Do Ha TP
- Dobson Annette J
- Dominguez Liria
- Donati Maria Benedetta
- Donfrancesco Chiara
- Dong Guanghui
- Dong Yanhui
- Donoso Silvana P
- Dorobantu Maria
- Dorosty Ahmad Reza
- Doua Kouamelan
- Döring Angela
- Dörr Marcus
- Dragano Nico
- Drygas Wojciech
- Du Shufa
- Duan Jia Li
- Duante Charmaine A
- Duarte de Oliveira Paula
- Duboz Priscilla
- Duleva Vesselka L
- Dulskiene Virginija
- Dumith Samuel C
- Dushpanova Anar
- Dwyer Terence
- Dyussupova Azhar
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Ebrahimi Narges
- Echeverría Guadalupe
- Eddie Ricky
- Eftekhar Ebrahim
- Efthymiou Vasiliki
- Egbagbe Eruke E
- Eggertsen Robert
- Eghtesad Sareh
- Eiben Gabriele
- Ekelund Ulf
- El Ammari Laila
- El Ati Jalila
- El-Khateeb Mohammad
- Eldemire-Shearer Denise
- Elliott Paul
- Enang Ofem
- Endevelt Ronit
- Engle-Stone Reina
- Erasmus Rajiv T
- Erem Cihangir
- Ergor Gul
- Eriksen Louise
- Eriksson Johan G
- Escobedo-de la Peña Jorge
- Eslami Saeid
- Esmaeili Ali
- Evans Alun
- Evans Roger G
- Ezzati Majid
- Faeh David
- Fagherazzi Guy
- Fakhradiyev Ildar
- Fakhretdinova Albina A
- Fall Caroline H
- Faramarzi Elnaz
- Farjam Mojtaba
- Farrugia Sant'Angelo Victoria
- Farzadfar Farshad
- Farzi Yosef
- Fattahi Mohammad Reza
- Fawwad Asher
- Fawzi Wafaie W
- Felix-Redondo Francisco J
- Ferguson Trevor S
- Fernandes Romulo A
- Fernández-Bergés Daniel
- Ferrante Daniel
- Ferrao Thomas
- Ferrari Gerson
- Ferrari Marika
- Ferrario Marco M
- Ferreccio Catterina
- Ferreira Haroldo S
- Ferrer Eldridge
- Ferrieres Jean
- Figueiró Thamara Hubler
- Fijalkowska Anna
- Fink Günther
- Fisberg Mauro
- Fischer Krista
- Foo Leng Huat
- Forsner Maria
- Fottrell Edward F
- Fouad Heba M
- Francis Damian K
- Franco Maria do Carmo
- Fras Zlatko
- Fraser Brooklyn
- Frontera Guillermo
- Fuchs Flavio D
- Fuchs Sandra C
- Fujiati Isti I
- Fujita Yuki
- Fumihiko Matsuda
- Furdela Viktoriya
- Furusawa Takuro
- Gabriela Stefan Adela
- Gaciong Zbigniew
- Gafencu Mihai
- Galán Cuesta Manuel
- Galbarczyk Andrzej
- Galcheva Sonya V
- Galenkamp Henrike
- Galeone Daniela
- Galfo Myriam
- Galvano Fabio
- Ganapathy Shubash
- Gao Jingli
- Gao Pei
- Garcia-de-la-Hera Manoli
- García Mérida María José
- García Solano Marta
- Gareta Dickman
- Garnett Sarah P
- Gaspoz Jean-Michel
- Gasull Magda
- Gaya Adroaldo Cesar Araujo
- Gaya Anelise Reis
- Gazzinelli Andrea
- Gehring Ulrike
- Geiger Harald
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- George Ronnie
- Gerdts Eva
- Ghaderi Ebrahim
- Ghamari Seyyed-Hadi
- Ghanbari Ali
- Ghasemi Erfan
- Gheorghe-Fronea Oana-Florentina
- Gialluisi Alessandro
- Giampaoli Simona
- Gianfagna Francesco
- Gieger Christian
- Gill Tiffany K
- Giovannelli Jonathan
- Gironella Glen
- Giwercman Aleksander
- Gkiouras Konstantinos
- Glushkova Natalya
- Godara Ramesh
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- Goldberg Marcel
- Goltzman David
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- Gonçalves Cordeiro da Silva Bruna
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- Gonçalves Mauer
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- González-Alvarez Ana D
- González-Gil Esther M
- González-Leon Margot
- González-Rivas Juan P
- González-Villalpando Clicerio
- González-Villalpando María-Elena
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- Gómez Gómez Jesús Humberto
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- Grafnetter Dušan
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- Guallar-Castillón Pilar
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- Haghshenas Rosa
- Hakimi Hamid
- Halkjær Jytte
- Hambleton Ian R
- Hamzeh Behrooz
- Hanekom Willem A
- Hange Dominique
- Hanif Abu AM
- Hantunen Sari
- Hao Jie
- Hardman Carla Menêses
- Hardy Louise
- Hari Kumar Rachakulla
- Harmer Lassen Tina
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- Hashemi-Shahri Seyed Mohammad
- Hassapidou Maria
- Hata Jun
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- He Jiang
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- Heidinger-Felső Regina
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- Henrique Rafael dos Santos
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- Hernandez Cadena Leticia
- Herrala Sauli
- Herrera Victor M
- Herrera-Cuenca Marianella
- Herter-Aeberli Isabelle
- Herzig Karl-Heinz
- Heshmat Ramin
- Heude Barbara
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- Homayounfar Reza
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- Hopman Wilma M
- Horimoto Andrea RVR
- Hormiga Claudia M
- Horta Bernardo L
- Houti Leila
- Howitt Christina
- Höfelmann Doroteia A
- Htay Thein Thein
- Htet Aung Soe
- Htike Maung Maung Than
- Hu Yonghua
- Huerta José María
- Huhtaniemi Ilpo Tapani
- Huiart Laetitia
- Huidumac Petrescu Constanta
- Husseini Abdullatif
- Huu Chinh Nguyen
- Huybrechts Inge
- Hwalla Nahla
- Hyska Jolanda
- Iacoviello Licia
- Iakupova Ellina M
- Ibarluzea Jesús
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- Ibrahim Mohsen M
- Igland Jannicke
- Ijoma Chinwuba
- Ikeda Nayu
- Ikram M Arfan
- Iñiguez Carmen
- Iotova Violeta
- Irazola Vilma E
- Ishida Takafumi
- Isiguzo Godsent C
- Islam Muhammad
- Islam Sheikh Mohammed Shariful
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- Jadoul Michel
- Jafar Tazeen
- Jallow Bakary
- James Kenneth
- Jamil Kazi M
- Jamrozik Konrad
- Jan Nataša
- Jansson Anna
- Janszky Imre
- Janus Edward
- Jarani Juel
- Jarnig Gerald
- Jarvelin Marjo-Riitta
- Jasienska Grazyna
- Jääskeläinen Tuija
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- Jennings Garry
- Jiang Chao Qiang
- Jimenez Ramon O
- Joffres Michel
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- Jöckel Karl-Heinz
- Judge Debra S
- Juolevi Anne
- Jurak Gregor
- Jurca Simina Iulia
- Juresa Vesna
- Jøran Kjerpeseth Lars
- Jørgensen Torben
- Kaaks Rudolf
- Kaducu Felix O
- Kadvan Agnes L
- Kafatos Anthony
- Kaj Mónika
- Kajantie Eero O
- Kakutia Natia
- Kalmatayeva Zhanna
- Kalter-Leibovici Ofra
- Kameli Yves
- Kanala Kodanda R
- Kannan Srinivasan
- Kapantais Efthymios
- Karaglani Eva
- Karakosta Argyro
- Karki Khem B
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- Kassi Anicet Adoubi
- Katchunga Philippe B
- Katibeh Marzieh
- Katz Joanne
- Katzmarzyk Peter T
- Kauhanen Jussi
- Kaur Prabhdeep
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- Kazakbaeva Gyulli M
- Kaze François F
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- Kállayová Daniela
- Kårhus Line L
- Ke Calvin
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- Keinan Boker Lital
- Keinänen-Kiukaanniemi Sirkka
- Kelishadi Roya
- Kelleher Cecily
- Kemper Han CG
- Kengne Andre P
- Keramati Maryam
- Kerimkulova Alina
- Kersting Mathilde
- Key Timothy
- Khader Yousef Saleh
- Khaledifar Arsalan
- Khalili Davood
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- Kheiri Bahareh
- Kheradmand Motahareh
- Khosravi Alireza
- Khouw Ilse MSL
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- Kim Jeongseon
- Kindblom Jenny M
- Kingston Andrew
- Klakk Heidi
- Klanarong Suntara
- Klanova Jana
- Klimek Magdalena
- Klimont Jeannette
- Klumbiene Jurate
- Knoflach Michael
- Kobel Susanne
- Koirala Bhawesh
- Kolle Elin
- Kolo Sanda M
- Kolsteren Patrick
- Korpelainen Raija
- Korrovits Paul
- Korzycka Magdalena
- Kos Jelena
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- Kouda Katsuyasu
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- Kristensen Peter Lund
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- Kroker-Lobos Maria F
- Krokstad Steinar
- Kromhout Daan
- Kruger Herculina S
- Kruger Ruan
- Kryst Łukasz
- Kubinova Ruzena
- Kuciene Renata
- Kujala Urho M
- Kujundzic Enisa
- Kulaga Zbigniew
- Kulimbet Mukhtar
- Kulothungan Vaitheeswaran
- Kumar R Krishna
- Kumari Meena
- Kunešová Marie
- Kurjata Pawel
- Kusuma Yadlapalli S
- Kutsenko Vladimir
- Kuulasmaa Kari
- Kyobutungi Catherine
- La Quang Ngoc
- Laamiri Fatima Zahra
- Laatikainen Tiina
- Labadarios Demetre
- Lachat Carl
- Lackner Karl J
- Lai Daphne
- Laid Youcef
- Lall Lachmie
- Lam Tai Hing
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- Lateva Mina P
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- Laurenzi Martino
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- Le Nguyen Bao Khanh
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- Le Tuyen D
- Lee Jeannette
- Lee Jeonghee
- Lee Paul H
- Lehtimäki Terho
- Lemogoum Daniel
- Leong Elvynna
- Leskošek Branimir
- Leszczak Justyna
- Leth-Møller Katja B
- Leung Gabriel M
- Levitt Naomi S
- Lhoste Victor PF
- Li Yanping
- Liivak Merike
- Lilly Christa L
- Lim Charlie
- Lim Wei-Yen
- Lima-Costa M Fernanda
- Lin Hsien-Ho
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- Lopes Luis
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- Lopes Oscar
- Lopez Tania
- Lopez-Garcia Esther
- Lotufo Paulo A
- Lozano José Eugenio
- Lukrafka Janice L
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- Lundqvist Annamari
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- Lustigová Michala
- M'Buyamba-Kabangu Jean-René
- Ma Guansheng
- Ma Jun
- Ma Xu
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- Machado-Rodrigues Aristides M
- Macia Enguerran
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- Maestre Gladys E
- Maggi Stefania
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- Mallikharjuna Rao Kodavanti
- Malta Deborah C
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- Manios Yannis
- Mann Jim I
- Mannix Masimango Imani
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- Manyanga Taru
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- Maruf Fatai A
- Maruszczak Katharina
- Marventano Stefano
- Masala Giovanna
- Mascarenhas Luis P
- Masinaei Masoud
- Masoodi Shariq R
- Mathiesen Ellisiv B
- Mathur Prashant
- Matijasevich Alicia
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- Matsudo Victor
- Matteo Giletta
- Matłosz Piotr
- Maulik Pallab K
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- Mazur Artur
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- McFarlane Shelly R
- McGarvey Stephen T
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- McLean Scott B
- McNairy Margaret L
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- Melkumova Marina
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- Menezes Ana Maria B
- Menon Geetha R
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- Meshram Indrapal I
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- Méndez Fabián
- Mi Jie
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- Mikkel Kairit
- Miller Jody C
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- Monterrubio-Flores Eric
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- Mopa Hermine T
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- Safarpour Ali Reza
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- Salhanova Akkumis
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- Salvetti Massimo
- Samoutian Margarita
- Sandjaja null
- Sans Susana
- Santa-Marina Loreto
- Santacruz Ethel
- Santos Diana A
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- Santos Maria Paula
- Santos Osvaldo
- Santos Rute
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- Saramies Jouko L
- Sardinha Luis B
- Sarrafzadegan Nizal
- Sathish Thirunavukkarasu
- Saum Kai-Uwe
- Savin Stefan
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- Sbaraini Mariana
- Scazufca Marcia
- Schaan Beatriz D
- Schaffrath Rosario Angelika
- Schargrodsky Herman
- Schienkiewitz Anja
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- Schmidt Börge
- Schmidt Carsten O
- Schmidt Ida Maria
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- Schnohr Peter
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- Schutte Aletta E
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- Servais Jennifer
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- Shamah-Levy Teresa
- Shamshirgaran Seyed Morteza
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- Sharma Sanjib K
- Sharman Almaz
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- Shayanrad Amaneh
- Shayesteh Ali Akbar
- Shengelia Lela
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- Shibuya Kenji
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- Shimony Tal
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- Silva Kelly Samara
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- Skoblina Natalia A
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- Slowikowska-Hilczer Jolanta
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- Somi Mohammad Hossein
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- Sparboe-Nilsen Bente
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- Staub Kaspar
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- Steinsbekk Silje
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- Stevanović Ranko
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- Suebsamran Phalakorn
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- Sun Liang
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- Sundström Johan
- Sung Yn-Tz
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- Suriyawongpaisal Paibul
- Sweis Nabil William G
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- Szponar Lucjan
- Sørensen Thorkild IA
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- Ševčíková Ľudmila
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- Tai E Shyong
- Takuro Furusawa
- Tambalis Konstantinos D
- Tammesoo Mari-Liis
- Tamosiunas Abdonas
- Tan Eng Joo
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- Tanrygulyyeva Maya
- Tanser Frank
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- Tarawneh Mohammed Rasoul
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- Tarqui-Mamani Carolina B
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- Taylor Anne
- Taylor Julie
- Tchibindat Félicité
- Te Velde Saskia
- Tebar William R
- Tell Grethe S
- Tello Tania
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- Tham Yih Chung
- Thankappan KR
- Theobald Holger
- Theodoridis Xenophon
- Thomas Nihal
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- Traissac Pierre
- Tran Thi Tuyet-Hanh
- Tremblay Mark S
- Triantafyllou Areti
- Trichopoulos Dimitrios
- Trichopoulou Antonia
- Trinh Oanh TH
- Trivedi Atul
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- Tsigga Maria
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- Tuomilehto Jaakko
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- van Valkengoed Irene GM
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- Vargas Luz Nayibe
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- Velika Biruta
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- Victora Cesar G
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- Viswanathan Bharathi
- Vladulescu Mihaela
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- Vourli Georgia
- Voutilainen Ari
- Völzke Henry
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- Vrijkotte Tanja GM
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- Wambiya Elvis OA
- Wan Bebakar Wan Mohamad
- Wan Mohamud Wan Nazaimoon
- Wanderley Júnior Rildo de Souza
- Wang Chongjian
- Wang Huijun
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- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S Goya
- Wareham Nicholas
- Wartha Olivia
- Weber Adelheid
- Webster-Kerr Karen
- Wedderkopp Niels
- Weghuber Daniel
- Wei Wenbin
- Weres Aneta
- Werner Bo
- Westbury Leo D
- Whincup Peter H
- Wichstrøm Lars
- Wickramasinghe Kremlin
- Widhalm Kurt
- Widyahening Indah S
- Więcek Andrzej
- Wild Philipp S
- Wilks Rainford J
- Willeit Johann
- Willeit Peter
- Williams Julianne
- Wilsgaard Tom
- Wirth James P
- Wojtyniak Bogdan
- Woldeyohannes Meseret
- Wolf Kathrin
- Wong Andrew
- Wong Emily B
- Wong Jyh Eiin
- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Hon-Yen
- Wu Jianfeng
- Wu Li Juan
- Wu Shouling
- Wyszyńska Justyna
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Li
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yasuharu Tabara
- Yépez García Martha
- Yiallouros Panayiotis K
- Yngve Agneta
- Yoosefi Moein
- Yoshihara Akihiro
- Yotov Yoto
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O
- Yu Yu-Ling
- Yu Yunjiang
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilová Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zaw Ko Ko
- Zayed Ayman A
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeljkovic Vrkic Tajana
- Zeng Yi
- Zentai Andrea
- Zhang Bing
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhecheva Yanitsa V
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zimmet Paul
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zoghlami Nada
- Zuñiga Cisneros Julio
- Zuziak Monika
- Żegleń Magdalena
- Łuszczki Edyta
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods: We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5-19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For school-aged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference) and obesity (BMI >2 SD above the median). Findings: From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining underweight or thinness. Interpretation: The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesity. Funding: UK Medical Research Council, UK Research and Innovation (Research England), UK Research and Innovation (Innovate UK), and European Union
Canada
- Author
- A. Appenzell
- A. Bevan
- A. Bevan
- A. Dueck
- A. Mitcham
- A. Mitcham
- A. Parkin
- A. Purdy
- A. Schroeder
- A. Schroeder
- A. Thomas
- A. Woodsworth
- A.B. Cameron
- Acorn Milton.
- Alianuk .Hrant.
- Amprimoz Alexandre.
- Anderson Patrick.
- Aquin Hubert.
- Atwood Margaret.
- Aubert de Gaspé Philippe.
- B. Amtmann.
- B. Barrie
- B. Davies
- B. Godard
- B. Godard
- B. Howell
- B. Lee.
- B. Lever.
- B. Nesbitt .
- B. Smith
- B. Stock
- B. Stock
- B. Tierney
- Bache William. B.
- Baltensperger Peter.
- Barbour Douglas.
- Barr Robert.
- Bartlett Brian.
- Bates Ronald.
- Bell John.
- Bennett Lawrence.
- Benson Eugene.
- Beresford-Howe Constance.
- Bessette Gerard.
- Biel Kent C.
- Birney Earle.
- Birney Earle.
- Bissett Bill.
- Blais Marie-Claire.
- Blaise Clark.
- Bodsworth Fred.
- Bolt Carol.
- Boston Stewart.
- Bowering George.
- Boxer Avi.
- Boyer Agnes.
- Boyle Harry J.
- Braithwaite Max.
- Brewster Elizabeth.
- Brewster Elizabeth.
- Brooke Frances.
- Brown Amy Hatchard.
- Buckaway Catherine M.
- Buckler Ernest.
- Bugnet Georges.
- Bullock Michael.
- Burrs Mick.
- C. Allen
- C. Fraser
- C. Levenson
- C. MacCulloch.
- C. Micheli
- C. Partridge
- C. Roberts-van Oordt
- C. Taylor
- C. Thomas
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- C.X. Ringrose
- C.X. Ringrose
- Callaghan Morley.
- Callaghan W.N.
- Cameron Eric.
- Campbell Don.
- Campbell J. Gounod.
- Canale Raymond.
- Capson Louis.
- Carrier Jean-Guy.
- Carrier Roch.
- Chadwick W.R.
- Clark Isabel.
- Clark Joan.
- Clemence Esme.
- Cohen Leonard.
- Cohen Matt.
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- Coleman Victor.
- Collier Diana G.
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- Connor Ralph.
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- D. Cameron
- D. Fetherling
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- D. Godfrey
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- D. Gutteridge
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- D. Jewison
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- D. Pacey
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- D.G. Jones
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- D.O. Spettigue
- Dalrymple Andrew Angus.
- Davies Robertson.
- Day Frank Parker.
- De Felice James.
- De Lissa Richard
- del Grande Louis.
- DeMille James.
- Denham Alice.
- Denison Merrill.
- Dickinson Don.
- Dienheim Anthony.
- Dlugacz Yosek.
- Dobb Ted.
- Dorsey Candas Jane.
- Doyle Mike.
- Duncan Sara Jeannette.
- Dunham Lynne.
- E. Godfrey
- E. Mandel
- E. McNamara
- E. Mullaly
- E. Strenski
- E. Waterston
- Edwards Caterina.
- Egyedi Béla.
- Elbl Richard
- Elgaard Elin.
- Engkent Gary.
- Evans Hubert.
- Everson R.G.
- F. Davey
- F. Davey
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- F. Sutherland
- F. Wah.
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- Farro E.
- Ferron Jacques.
- Fielden Charlotte.
- Fox Gail.
- Fraser Raymond.
- Fraser Sylvia.
- Freeman David.
- French David.
- French Richard.
- Friedman Irene.
- Frye Northrop.
- G. Amabile
- G. Bowering
- G. Bowering
- G. Clever
- G. Elliott
- G. Noonan
- G. Siebrasse
- G. Stow
- G. Stow
- G. Warkentin
- G. Warkentin
- G. Warkentin
- G. Woodcock
- G. Woodcock
- G. Woodcock
- G. Woodcock
- G. Woodcock
- G. Woodcock
- Gallant Mavis.
- Galt John.
- Garner Hugh.
- Garrett Ronald.
- Gasparini Len.
- Georges Bugnet
- Gerard Lance.
- Gibbs Robert.
- Gilbert Gerry.
- Glassco John.
- Godfrey David.
- Goudie Elizabeth.
- Gray Michael.
- Green Paul.
- Grills Barry W.
- Gustafson Ralph.
- H. Bouraoui
- H. Garner
- H. Rosengarten
- H. Rosengarten
- H. Sonthoff
- Harris Christie.
- Harrison Susan Frances.
- Heath Terrence.
- Heath Terrence.
- Heavysege Charles.
- Helwig David.
- Hendry Tom.
- Hickman Tom.
- Hodder Blanche.
- Hodgins Jack.
- Hollingsworth Mike.
- Holmes Abraham S.
- Hood Hugh
- Horwood Harold.
- Howe Joseph.
- Hubert Cam.
- Hébert Anne.
- I. Bassett
- I. Montagnes
- I. Nadel
- I.B. Nadel
- Ignatow Rose Graubart.
- J. Ayre
- J. Gibbs
- J. Grifhth
- J. Harcourt
- J. Jocelyn
- J. Mays
- J. Metcalf
- J. Moss
- J. Noonan
- J. Orange
- J. Rosenblatt
- J. Sheppard
- J. Sherman
- J. Sutherland.
- J. Zilber
- J.M. Purcell
- J.W. Lennox
- Jack Donald.
- Jacques Ferron
- Jameson Anna.
- Jean Barbeau
- Johnson Linda Wilkene.
- Johnston George.
- Julian Marilyn.
- K. Dewar
- K. Mulhallen
- K. Thompson
- Kartzmark Ross.
- Keeling Nora.
- Kelly Arthur J.
- Kent Valerie.
- Kinch Martin.
- King David.
- Kirby William.
- Klein A.M.
- Klinck Carl.
- Knight David.
- Kowal Vic.
- Kroetsch Robert.
- L. Dudek
- L. Ricou
- L. Vernon
- Lachance Bertrand.
- Ladoo Harold Sonny.
- Lambert Rick.
- Lampman Archibald.
- Laurence Margaret.
- Laurentian U.
- Layton Irving.
- Lazarus John.
- Leacock Stephen.
- Leckner Carol H.
- Lee Dennis
- Lee Ronald.
- Leprohen Rosanna.
- Leslie Kenneth.
- Livesay Dorothy.
- Loby Louis.
- Lonneberg Lyle.
- Lord Peter.
- Lowry Malcolm.
- M. Atwood
- M. Atwood
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- M. Brown
- M. Dawe
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- M. Estok
- M. J. Edwards
- M. Lalonde
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- M. Laurence
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- M. Potts
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- M. Wolfe
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- M.H. Scargill
- M.J. Ward
- M.L. Ross
- MacCormack Terry.
- MacEwen Gwendolyn.
- MacKenzie Alan.
- MacLennan Hugh.
- MacLeod Alistair.
- MacMillan Ian.
- MacSkimming Roy.
- MacSween R.J.
- Mandel Eli.
- Margoshes Dave.
- Martindale Herb.
- Mason Michael.
- McCulloch Thomas.
- McDorxald David.
- McFadden David.
- McGillivray Judy.
- McIntyre James.
- McKenna Robert Ivan.
- McKinnon Barry.
- McLachlan Richard J.
- McNamara Eugene.
- Metcalf John.
- Michel Tremblay
- Miller Lily Poritz.
- Mirolla Michael.
- Mitchell Ken.
- Mitchell Ken.
- Mitchell W.O.
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- Monk Douglas.
- Montgomery L.M.
- Moore Brian.
- Moore Mavor.
- Moore Peter.
- Morissey Philip.
- Mowat Farley.
- Munro Alice.
- N. Kattan
- N.B. Annual sub.
- New W.H.
- Newlove John.
- Newlove John.
- Newman C.J.
- Newman Jerry.
- Nichol B.
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- Nowlan Alden.
- O'Brien Bill T.
- O'Brien Bill T.
- Ondaatje Michael.
- Osborne John.
- Ostenso Martha.
- P. Barclay
- P. Grosskurth
- P. Lane
- P. Page
- P. Rogers
- P. Stevens
- P. Stevens
- P. Webb
- Page P.K.
- Palmer Marian.
- Palomba Lauro.
- Park Lisa.
- Parker Gilbert.
- Payerle George.
- Perrault E.G.
- Petch Steve.
- Pifler Phil.
- Pilk Henry.
- Plourde Marc.
- Pollock Sharon.
- Potrebenko Helen.
- Powell D. Reid.
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- R. Brandeis
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- R. Gustafson
- R. Harrison
- R. Kalman
- R. MacSkimming
- R. Mathews
- R. Murray.
- R. Skelton
- R. Smith
- R. Sutherland
- R. Willmott
- R.T. Robertson
- Raddall Thomas.
- Rafferty Larry.
- Ravel Aviva.
- Reaney James.
- Reiter David Phillip.
- Renner Vivian.
- Rhind Pauline Elizabeth.
- Richards David.
- Richardson John.
- Richler Mordecai.
- Rikki.
- Robert Gurik
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- Roberts Kevin.
- Roberts Kevin.
- Roch Carrier
- Rooke Leon.
- Rosen Sheldon.
- Rosenthal Helene.
- Rosqui Carolyn.
- Ross James.
- Ross Sinclair.
- Rosta Helen.
- Roy Gabrielle.
- S. Atherton
- S. Djwa
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- S. Djwa
- S. Djwa
- S. Djwa
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- S. Mayne
- S. McCutcheon
- S. Repo
- S. Scobie
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- Salutin Rick.
- Sangster Charles.
- Schleich David.
- Schull Joseph.
- Scobie Stephen.
- Scobie Stephen.
- Scott Munroe.
- Seton Ernest
- Shein Brian.
- Sherman Kenneth.
- Sherra Connie.
- Shovella Brock.
- Simons Beverley.
- Smith Goldwin.
- Smith Ray.
- Smith Robert.
- Smyth Donna E.
- Solokoff Steven.
- Solway David.
- Stead Robert J.
- Stegmayer Nancy.
- Stein David Lewis.
- Such Peter.
- Sutherland Ronald.
- Sutherland Barry.
- Sutherland Fraser.
- Sutherland John.
- Svoboda Terese.
- Swerdlow Robert.
- T. Hendry
- T. Marshall
- Tata Saam.
- Taylor Ron.
- Theatre Passe Muraille
- Thomas Audrey.
- Thompson Kent.
- Thomson Edward William.
- Thornton Joan.
- Thériault Yves.
- Todd Chris.
- Tomlinson Randy.
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- Tyhurst Rob.
- Ursell Barbara.
- V. Reid
- V. Sharman
- W. Aide
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- W.F.E. Morley
- W.H. New
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- W.J. Keith
- Waddington Miriam.
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- Walker George.
- Ward Norman.
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- Watmough David.
- Watson Sheila.
- Wayman Tom.
- Webb Phyllis.
- Weinzweig Helen.
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- White Derryll.
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- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study