57 research outputs found

    Imagerie médicale et patrimoine anthropologique : vers un contrôle total de la chaîne des traitements dans l'analyse morphométrique tridimensionnelle

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    International audienceThe objective of the present paper is to give some data in medical imaging and 3D reconstruction applied in bio-anthropological field. Scanner CT images are a powerful tool to explore internal structures, to reconstruct incomplete bones and to give biomechanical interpretation based on bone morphology. Further, we propose to argument a cultural hypothesis relatively to a deliberate treatment concerning a human boneNous présentons quelques applications de l’imagerie médicale et de la reconstitution 3D dans le domaine de l’anthropologie biologique. L’acquisition et l’exploitation d’images scanner CT permettent d’accéder aux structures internes, de reconstituer des parties manquantes et d’exploiter des caractéristiques bio-mécaniques. Nous proposons également l’argumentation d’une hypothèse culturelle en relation avec un aménagement pratiqué sur un os humain

    THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

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    The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate

    THE CONCISE GUIDE TO PHARMACOLOGY 2019/20 : G protein- coupled receptors

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    The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14748. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.Peer reviewe

    THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.

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    The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate

    The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors.

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    peer reviewedThe Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.16177. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate

    IS THE IRRIGATION WATER DEMAND REALLY CONVEX?

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    The seasonal irrigation water demand under uncertainty, which lies at the core of this paper, is still very roughly known. We know, however, that irrigated agriculture accounts for a large proportion of water use, especially in many water-scarce areas. In this paper, we estimate the irrigation water demand, for various climatic conditions characterizing the distribution of the necessarily stochastic, demand functions under uncertainty. We use a dynamic programming model to represent the farmer's decision program under uncertainty. A crop-growth simulation model (EPIC-PHASE), provides the response function to the decisions taken and climatic events and is linked to a CRRA utility function representing the farmer's objective function. This model is used to generate the data allowing the estimation of irrigation water demand by a nonparametric procedure. An application to irrigation water demand is proposed in the South-West of France. We show that the estimated demand functions present four main areas: For very small quantities, where the farmer considers water as an essential input to crop growth, the demand is inelastic. The second area corresponds to mean quantities where the plant has reached a satisfactory level of growth; water is no more an essential input and is not yet a risk reducing input. The farmer is more responsive to change in water price. But, we find a third, non-intuitive, area for larger quantities where the water is a risk reducing input and the demand becomes inelastic again. The last area is classic, the water demand is obviously elastic for important total water quantities. This result is of great importance to analyze a regulation policy

    L'Estuaire, vol. 24 (2)

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    Éditorial -- Achille Tanguay et Antoinette Sergerie: les grands-parents maternels de Céline Dion -- Pour rappeler une étape importante du développement de Baie-Comeau -- Le "Vocabulaire micmac" de Joseph Hamel. L'histoire d'une cueillette de données linguistiques. Partie 1: Contexte linguistique et milieu de vie -- Donat Couture: journalier, bûcheron, menuisier -- La grange à dîme de Ste-Flavie: vestige d'une paroisse agricole -- Vieux écrits: Extraits du journal nautique de "La Canadienne" vapeur préposé à la protection des pêcheries de W. Wakeham -- Nouvelles brèves -- Des livres à lire
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