Power spectra of the natural input to the visual system

AbstractThe efficient coding hypothesis posits that sensory systems are adapted to the regularities of their signal input so as to reduce redundancy in the resulting representations. It is therefore important to characterize the regularities of natural signals to gain insight into the processing of natural stimuli. While measurements of statistical regularity in vision have focused on photographic images of natural environments it has been much less investigated, how the specific imaging process embodied by the organism’s eye induces statistical dependencies on the natural input to the visual system. This has allowed using the convenient assumption that natural image data are homogeneous across the visual field. Here we give up on this assumption and show how the imaging process in a human model eye influences the local statistics of the natural input to the visual system across the entire visual field. Artificial scenes with three-dimensional edge elements were generated and the influence of the imaging projection onto the back of a spherical model eye were quantified. These distributions show a strong radial influence of the imaging process on the resulting edge statistics with increasing eccentricity from the model fovea. This influence is further quantified through computation of the second order intensity statistics as a function of eccentricity from the center of projection using samples from the dead leaves image model. Using data from a naturalistic virtual environment, which allows generation of correctly projected images onto the model eye across the entire field of view, we quantified the second order dependencies as function of the position in the visual field using a new generalized parameterization of the power spectra. Finally, we compared this analysis with a commonly used natural image database, the van Hateren database, and show good agreement within the small field of view available in these photographic images. We conclude by providing a detailed quantitative analysis of the second order statistical dependencies of the natural input to the visual system across the visual field and demonstrating the importance of considering the influence of the sensory system on the statistical regularities of the input to the visual system

An ``Improved" Lattice Study of Semi-leptonic Decays of D-Mesons

We present results of a lattice computation of the matrix elements of the vector and axial-vector currents which are relevant for the semi-leptonic decays $D \rightarrow K$ and $D \rightarrow K^*$. The computations are performed in the quenched approximation to lattice QCD on a $24^3 \times 48$ lattice at $\beta=6.2$, using an $O(a)$-improved fermionic action. In the limit of zero lepton masses the semi-leptonic decays $D \rightarrow K$ and $D \rightarrow K^*$ are described by four form factors: $f^{+}_K,V,A_1$ and $A_2$, which are functions of $q^2$, where $q^{\mu}$ is the four-momentum transferred in the process. Our results for these form factors at $q^2=0$ are: f^+_K(0)=0.67 \er{7}{8} , V(0)=1.01 \err{30}{13} , A_1(0)=0.70 \err{7}{10} , A_2(0)=0.66 \err{10}{15} , which are consistent with the most recent experimental world average values. We have also determined the $q^2$ dependence of the form factors, which we find to be reasonably well described by a simple pole-dominance model. Results for other form factors, including those relevant to the decays \dpi and \drho, are also given.Comment: 41 pages, uuencoded compressed postscript file containing 14 figures, LaTeX, Edinburgh Preprint 94/546 and Southampton Preprint SHEP 93/94-3

Mitigating Air Delay: An analysis of the Collaborative Trajectory Options Program

Congestion is a problem at major airports in the world. Airports, especially high-traffic ones, tend to be the bottleneck in the air traffic control system. The problem that arises for the airspace planner is how to mitigate air congestion and its consequent delay, which causes increased cost for airlines and discomfort for passengers. Most congestion problems are fixed on the day of operations in a tactically manner using operational enhancements measures. Collaborative Trajectory Options Program (CTOP) aims to improve air traffic management (ATM) considering National Airspace System (NAS) users business goals, particularities faced by each flight and airspace restrictions, making this process more flexible and financially stable for those involved. In CTOP, airlines share their route preferences with the air control authority, combining delay and reroute. When CTOP is created, each airline might decide its strategy without knowledge of other airline’s flights. Current solutions for this problem are based on greedy methods and game theory. There is potential space to improve. This paper examines CTOP and identifies important strategic changes to ATM adopting this philosophy, particularly in Brazil. Document type: Articl

Colloid-stabilized emulsions: behaviour as the interfacial tension is reduced

We present confocal microscopy studies of novel particle-stabilized emulsions. The novelty arises because the immiscible fluids have an accessible upper critical solution temperature. The emulsions have been created by beginning with particles dispersed in the single-fluid phase. On cooling, regions of the minority phase nucleate. While coarsening these nuclei become coated with particles due to the associated reduction in interfacial energy. The resulting emulsion is arrested, and the particle-coated interfaces have intriguing properties. Having made use of the binary-fluid phase diagram to create the emulsion we then make use of it to study the properties of the interfaces. As the emulsion is re-heated toward the single-fluid phase the interfacial tension falls and the volume of the dispersed phase drops. Crumpling, fracture or coalescence can follow. The results show that the elasticity of the interfaces has a controlling influence over the emulsion behaviour.Comment: Submitted for the proceedings of the 6th Liquid Matter Conference, held in Utrecht (NL) in July 200

Illusory Body Ownership Affects the Cortical Response to Vicarious Somatosensation

Fundamental human feelings such as body ownership (“this” body is “my” body) and vicariousness (first-person-like experience of events occurring to others) are based on multisensory integration. Behavioral links between body ownership and vicariousness have been shown, but the neural underpinnings remain largely unexplored. To fill this gap, we investigated the neural effects of altered body ownership on vicarious somatosensation. While recording functional brain imaging data, first, we altered participants’ body ownership by robotically delivering tactile stimulations (“tactile” stroking) in synchrony or not with videos of a virtual hand being brushed (“visual” stroking). Then, we manipulated vicarious somatosensation by showing videos of the virtual hand being touched by a syringe’s plunger (touch) or needle (pain). Only after the alteration of body ownership (synchronous visuo-tactile stroking) and specifically during late epochs of vicarious somatosensation, vicarious pain was associated with lower activation in premotor and anterior cingulate cortices with respect to vicarious touch. At the methodological level, the present study highlights the importance of the neural response’s temporal evolution. At the theoretical level, it shows that the higher-level (cognitive) impact of a lower-level (sensory) body-related processing (visuo-tactile) is not limited to body ownership but also extends to other psychological body-related domains, such as vicarious somatosensation

Excessive collagen turnover products are released during colorectal cancer progression and elevated in serum from metastatic colorectal cancer patients

During cancer progression, the homeostasis of the extracellular matrix becomes imbalanced with an excessive collagen remodeling by matrix metalloproteinases. As a consequence, small protein fragments of degraded collagens are released into the circulation. We have investigated the potential of protein fragments of collagen type I, III and IV as novel biomarkers for colorectal cancer. Specific fragments of degraded type I, III and IV collagen (C1M, C3M, C4M) and type III collagen formation (Pro-C3) were assessed in serum from colorectal cancer patients, subjects with adenomas and matched healthy controls using well-characterized and validated ELISAs. Serum levels of the biomarkers were significantly elevated in colorectal cancer patients compared to subjects with adenomas (C1M, Pro-C3, C3M) and controls (C1M, Pro-C3). When patients were stratified according to their tumour stage, all four biomarkers were able to differentiate stage IV metastatic patients from all other stages. Combination of all markers with age and gender in a logistic regression model discriminated between metastatic and non-metastatic patients with an AUROC of 0.80. The data suggest that the levels of these collagen remodeling biomarkers may be a measure of tumour activity and invasiveness and may provide new clinical tools for monitoring of patients with advanced stage colorectal cancer

Biomarkers of aging in Drosophila

Low environmental temperature and dietary restriction (DR) extend lifespan in diverse organisms. In the fruit fly Drosophila, switching flies between temperatures alters the rate at which mortality subsequently increases with age but does not reverse mortality rate. In contrast, DR acts acutely to lower mortality risk; flies switched between control feeding and DR show a rapid reversal of mortality rate. Dietary restriction thus does not slow accumulation of aging-related damage. Molecular species that track the effects of temperatures on mortality but are unaltered with switches in diet are therefore potential biomarkers of aging-related damage. However, molecular species that switch upon instigation or withdrawal of DR are thus potential biomarkers of mechanisms underlying risk of mortality, but not of aging-related damage. Using this approach, we assessed several commonly used biomarkers of aging-related damage. Accumulation of fluorescent advanced glycation end products (AGEs) correlated strongly with mortality rate of flies at different temperatures but was independent of diet. Hence, fluorescent AGEs are biomarkers of aging-related damage in flies. In contrast, five oxidized and glycated protein adducts accumulated with age, but were reversible with both temperature and diet, and are therefore not markers either of acute risk of dying or of aging-related damage. Our approach provides a powerful method for identification of biomarkers of aging.This work was supported by the Wellcome Trust and in part by I+D grants from the Spanish Ministry of Education and Science (BFU2006-14495 ⁄ BFI), the Spanish Ministry of Health (ISCIII, Red de Envejecimiento y Fragilidad, RD06 ⁄ 0013 ⁄ 0012), and the Generalitat of Catalunya (2005SGR00101) to R.P; the Spanish Ministry of Health (FIS PI081843), Spanish Ministry of Education and Science (AGL2006-12433), and ‘‘La Caixa’’ Foundation to M.P.O. Also supported by the Max Planck Society (J.J. and L.P), COST B-35 Action; Research into Ageing (A.J.L.) and the Medical Research Council and National Institutes of Health (P01 AG025901, PL1 AG032118 and P30 AG025708) (M.D.B.)

Influência da temperatura no comportamento alimentar e interação de filhotes de Kinosternon scorpioides em cativeiro.

O muçuã (Kinosternon scorpioides) é um cágado bastante apreciado em toda a região amazônica, sendo um quelônio com características zootécnicas promissoras na aquicultura. Contudo, há poucos estudos que abordem o comportamento alimentar desta espécie em cativeiro. Portanto, objetivou-se com o presente estudo avaliar a influencia da temperatura no comportamento alimentar e a interação de filhotes de muçuã (Kinosternon scopioides), mantidos em três diferentes temperaturas (29,5ºC, 31,5ºC e 33,5ºC). O experimento foi conduzido no Projeto Bio-Fauna/ISARH/UFRA, sediado em Belém, Pará. Um total de 84 filhotes de muçuãs foram subdivididos em seis lotes-berçário, distribuídos dois a dois em estufas mantidas sob diferentes temperaturas, 29,5ºC, 31,5ºC e 33,5ºC, durante os primeiros 90 dias de vida. Os animais foram alimentados com ração para peixe, na proporção de 2% do peso vivo/dia, distribuída em ofertas semanais. Quinzenalmente foram realizadas pesagens e medições individuais, para avaliação do desenvolvimento corpóreo e ajuste de alimentação. Constatou-se efeito significativo da temperatura em todos os parâmetros analisados. Durante o experimento foi notado uma diminuição na frequência alimentar em todos os tratamentos, porém os animais da temperatura mais alta do experimento (33,5ºC) apresentaram a maior diminuição no interesse pelo alimento durante o período de oferta/observação, portanto os mesmos tiveram o pior desempenho quando comparado aos demais lotes

Strange and charm mesons at fair

We study the properties of strange and charm mesons in hot and dense matter within a self-consistent coupled-channel approach for the experimental conditions of density and temperature expected for the CBM experiment at FAIR/GSI. The in-medium solution at finite temperature accounts for Pauli blocking effects, mean-field binding of all the baryons involved, and meson self-energies. We analyse the behaviour in this hot and dense environment of dynamically-generated baryonic resonances together with the evolution with density and temperature of the strange and open-charm meson spectral functions. We test the spectral functions for strange mesons using energy-weighted sum rules and finally discuss the implications of the properties of charm mesons on the Ds0(2317) and the predicted X(3700) scalar resonances.Molina Peralta, Raquel, [email protected] ; Nieves Pamplona, Juan Miguel, [email protected] ; Oset Báguena, Eulogio, [email protected]

Strange and charm mesons at fair

We study the properties of strange and charm mesons in hot and dense matter within a self-consistent coupled-channel approach for the experimental conditions of density and temperature expected for the CBM experiment at FAIR/GSI. The in-medium solution at finite temperature accounts for Pauli blocking effects, mean-field binding of all the baryons involved, and meson self-energies. We analyse the behaviour in this hot and dense environment of dynamically-generated baryonic resonances together with the evolution with density and temperature of the strange and open-charm meson spectral functions. We test the spectral functions for strange mesons using energy-weighted sum rules and finally discuss the implications of the properties of charm mesons on the Ds0(2317) and the predicted X(3700) scalar resonances.Molina Peralta, Raquel, [email protected] ; Nieves Pamplona, Juan Miguel, [email protected] ; Oset Báguena, Eulogio, [email protected]