Progress in the Surveillance of Respiratory Syncytial Virus (Rsv) in Europe: 2001-2008

Item does not contain fulltextRespiratory syncytial virus (RSV) surveillance is important to get insight into the burden of disease and epidemic pattern of RSV infection. This information is useful for healthcare resource allocation as well as the timing of preventive messages and palivizumab prophylaxis. For influenza surveillance the European Influenza Surveillance Scheme (EISS) was established in 1996, but no surveillance platform is available for RSV. To improve surveillance an RSV Task Group was established in 2003 and recommendations for RSV surveillance were developed. By 2008, progress was made for four out of six recommendations: the number of European countries testing specimens for RSV increased from six to fourteen; nose and/or throat swabs were generally used for detection of influenza and RSV; a total of 25 laboratories performed molecular testing for diagnosis and participated in a quality control assessment for RSV with an overall good performance; four of the ten countries that joined EISS in 2004 started reporting RSV detections in addition to influenza in the period 2004-8. Limited progress was achieved for standardising methods and the development of a sentinel surveillance system of representative hospitals. Improving RSV surveillance is possible by further harmonising the data collection and increased reporting of RSV

The Use and Abuse of Business History

The use of history in vocational undergraduate courses is contested. Although there has been a recent push to bolster the teaching of history in Australian secondary schools, history in business courses still often seems only to linger at the margins. Pleas to include historical approaches to business education are made from time to time that suggest a role for history in the curriculum that is essentially not historical – they often highlight the skills history students develop or the broader humanistic understanding usually associated with historical knowledge, not necessarily ones based on what is unique to history. This paper argues that historical analysis is essentially different than that represented by other traditional disciplines and that this fundamental aspect of history should be at the core of arguments to include business history in course curriculums.The symposium is organised on behalf of AAHANZBS by the Business and Labour History Group, The University of Sydney, with the financial support of the University’s Faculty of Economics and Business

Lifting the Shroud: Government, Investment Banks and Power in Post Financial Crisis United Kingdom - A critical deconstruction of the relationship between government and investment banks in the United Kingdom post global financial crisis (2007 – 2011)

The late 2000s Global Financial Crisis swept the advanced world and spilled into the developing, creating chaos in its wake. At the crux of the crisis were the high-risk activities of investment banks in the developed world – and especially United Kingdom. Since then, academic and public discussion has revolved around the questionable relationship between investment banks and government that resulted in subpar regulation and the costly bank ‘bailouts’ of 2008 and 2009. What this thesis will to do is holistically assess how the power relationship between British investment banks and the United Kingdom government has evolved since the crisis, utilising Doris Fuchs’ Three Dimensional Approach to Business Power and Governance and a wide array of research to address those structural, instrumental and discursive elements of business power

Spin battery operated by ferromagnetic resonance

Precessing ferromagnets are predicted to inject a spin current into adjacent conductors via Ohmic contacts, irrespective of a conductance mismatch with, for example, doped semiconductors. This opens the way to create a pure spin source spin battery by the ferromagnetic resonance. We estimate the spin current and spin bias for different material combinations.Comment: The estimate for the magnitude of the spin bias is improved. We find that it is feasible to get a measurable signal of the order of the microwave frequency already for moderate rf intensitie

Cancer Stem Cells and Side Population Cells in Breast Cancer and Metastasis

In breast cancer it is never the primary tumour that is fatal; instead it is the development of metastatic disease which is the major cause of cancer related mortality. There is accumulating evidence that suggests that Cancer Stem Cells (CSC) may play a role in breast cancer development and progression. Breast cancer stem cell populations, including side population cells (SP), have been shown to be primitive stem cell-like populations, being long-lived, self-renewing and highly proliferative. SP cells are identified using dual wavelength flow cytometry combined with Hoechst 33342 dye efflux, this ability is due to expression of one or more members of the ABC transporter family. They have increased resistance to chemotherapeutic agents and apoptotic stimuli and have increased migratory potential above that of the bulk tumour cells making them strong candidates for the metastatic spread of breast cancer. Treatment of nearly all cancers usually involves one first-line agent known to be a substrate of an ABC transporter thereby increasing the risk of developing drug resistant tumours. At present there is no marker available to identify SP cells using immunohistochemistry on breast cancer patient samples. If SP cells do play a role in breast cancer progression/Metastatic Breast Cancer (MBC), combining chemotherapy with ABC inhibitors may be able to destroy both the cells making up the bulk tumour and the cancer stem cell population thus preventing the risk of drug resistant disease, recurrence or metastasis

Protocol for the evaluation of clinical data collected by the European Influenza Surveillance Scheme.

A protocol to evaluate the clinical data collected by the European Influenza Surveillance Scheme (EISS) is now available at http://www.eiss.org/news.cgi (1). It has been developed to help standardise surveillance procedures within EISS and harmonise the clinical influenza data that is being collected, and is part of a larger quality control project within EISS that includes the assessment of virological testing for influenza and respiratory syncytial virus (2)

Lessons learned from the global surveillance of pandemic influenza, the different communication strategies and the impact on Europe’s public health response.

After the first case of Mexican flu was reported in early spring 2009, a wave of reported cases went quickly through the (scientific) media. Pandemic influenza A(H1N1) activity was reported in all continents, but most countries were affected during summer 2009 in Latin America, Oceania and Asia, followed by countries in North America and Europe during late summer/autumn. Whereas the geographical distribution of the pandemic virus was clear, the severity pattern of the pandemic was far from clear. Consequently risk communication about the pandemic was not ideal and left critics with scepticism on whether the right measures were taken and money was spent in the correct way. We will review the global surveillance data of pandemic H1N1 and the different communication approaches to draw lessons on how this was arranged and how this can be better organized in the future

Health monitoring in sentinel practice networks: the contribution of primary care.

BACKGROUND: The health monitoring programme of the European Commission has proposed a set of health indicators whereby the health status of member states can be measured. As part of that programme we considered how primary care might contribute relevant data. METHODS: Using a questionnaire distributed to personal contacts and health authorities, we investigated the activities of sentinel practice networks and sought opinions on the place of primary care as a provider of information on health indicators. Studies on the prevalence of diabetes mellitus and on the incidence of chickenpox were undertaken within selected networks. RESULTS: 33 networks were found who provided relevant information on a timely and continuing basis. Contributions varied; some were limited to monitoring influenza but others recorded morbidity data from every consultation. Recording methods ranged from the paper based to fully automated systems in which all morbidity was coded electronically at data entry. The study of diabetes mellitus showed less variation between national networks than currently suggested on the WHO database. For chickenpox we estimated the incidence of cases not presenting to general practitioners ranged between 3 and 27%. CONCLUSIONS: Information on health indicators needs to come from the place where relevant care is delivered; for many conditions that is from primary care. It can be delivered from appropriately resourced practices where the population is defined, the practice populations are nationally representative and data lection is automated. (aut. ref.