LA DISCUSIÓN SALARIAL EN EL COOPERATIVISMO

El concepto de salario surgió y se desarrolló para dar cuenta de una relación de trabajo ajena a la identidad del sector cooperativo. Si bien es comprensible que el legislador pretenda extender la tutela de ciertos derechos laborales al conjunto de los trabajadores, debiera comprenderse mejor la racionalidad y lógica del cooperativismo con el fin de evitarcategorías económicas y jurídicas pertinentes para las empresas basadas en el capital pero inadecuadas para el caso de las empresas basadas en el trabajo

Self-consistent treatment of thermal effects in neutron-star post-mergers: observational implications for third-generation gravitational-wave detectors

We assess the impact of accurate, self-consistent modelling of thermal effects in neutron-star merger remnants in the context of third-generation gravitational-wave detectors. This is done through the usage, in Bayesian model selection experiments, of numerical-relativity simulations of binary neutron star (BNS) mergers modelled through: a) nuclear, finite-temperature (or ``tabulated'') equations of state (EoSs), and b) their simplifed piecewise (or ``hybrid'') representation. These cover four different EoSs, namely SLy4, DD2, HShen and LS220. Our analyses make direct use of the Newman-Penrose scalar $\psi_4$ outputted by numerical simulations. Considering a detector network formed by three Cosmic Explorers, we show that differences in the gravitational-wave emission predicted by the two models are detectable with a natural logarithmic Bayes Factor $\log{\cal{B}}\geq 5$ at average distances of $d_L \simeq 50$Mpc, reaching $d_L \simeq 100$Mpc for source inclinations $\iota \leq 0.8$, regardless of the EoS. This impact is most pronounced for the HShen EoS. For low inclinations, only the DD2 EoS prevents the detectability of such modelling differences at $d_L \simeq 150$Mpc. Our results suggest that the usage a self-consistent treatment of thermal effects is crucial for third-generation gravitational wave detectors.Comment: 9 pages, 3 Figure

Assessing the accuracy of GEDI data from canopy height and aboveground biomass estimates in Mediterranean forests

Global Ecosystem Dynamics Investigation (GEDI) satellite mission is expanding the spatial bounds and temporal resolution of large-scale mapping applications. Integrating the recent GEDI data into Airborne Laser Scanning (ALS)-derived estimations represents a global opportunity to update and extend forest models based on area based approaches (ABA) considering temporal and spatial dynamics. This study evaluates the effect of combining ALS-based aboveground biomass (AGB) estimates with GEDI-derived models by using temporally coincident datasets. A gradient of forest ecosystems, distributed through 21,766 km2 in the province of Badajoz (Spain), with different species and structural complexity, was used to: (i) assess the accuracy of GEDI canopy height in five Mediterranean Ecosystems and (ii) develop GEDI-based AGB models when using ALS-derived AGB estimates at GEDI footprint level. In terms of Pearson’s correlation (r) and rRMSE, the agreement between ALS and GEDI statistics on canopy height was stronger in the denser and homogeneous coniferous forest of P. pinaster and P. pinea than in sparse Quercus-dominated forests. The GEDIderived AGB models using relative height and vertical canopy metrics yielded a model efficiency (Mef) ranging from 0.31 to 0.46, with a RMSE ranging from 14.13 to 32.16 Mg/ha and rRMSE from 38.17 to 84.74%, at GEDI footprint level by forest type. The impact of forest structure confirmed previous studies achievements, since GEDI data showed higher uncertainty in highly multilayered forests. In general, GEDI-derived models (GEDI-like Level4A) underestimated AGB over lower and higher ALS-derived AGB intervals. The proposed models could also be used to monitor biomass stocks at large-scale by using GEDI footprint level in Mediterranean areas, especially in remote and hard-to-reach areas for forest inventory. The findings from this study serve to provide an initial evaluation of GEDI data for estimating AGB in Mediterranean forestinfo:eu-repo/semantics/publishedVersio

Assessing the Accuracy of GEDI Data for Canopy Height and Aboveground Biomass Estimates in Mediterranean Forests

[EN], Global Ecosystem Dynamics Investigation (GEDI) satellite mission is expanding the spatial bounds and temporal resolution of large-scale mapping applications. Integrating the recent GEDI data into Airborne Laser Scanning (ALS)-derived estimations represents a global opportunity to update and extend forest models based on area based approaches (ABA) considering temporal and spatial dynamics. This study evaluates the effect of combining ALS-based aboveground biomass (AGB) estimates with GEDI-derived models by using temporally coincident datasets. A gradient of forest ecosystems, distributed through 21,766 km2 in the province of Badajoz (Spain), with different species and structural complexity, was used to: (i) assess the accuracy of GEDI canopy height in five Mediterranean Ecosystems and (ii) develop GEDI-based AGB models when using ALS-derived AGB estimates at GEDI footprint level. In terms of Pearson’s correlation (r) and rRMSE, the agreement between ALS and GEDI statistics on canopy height was stronger in the denser and homogeneous coniferous forest of P. pinaster and P. pinea than in sparse Quercus-dominated forests. The GEDI-derived AGB models using relative height and vertical canopy metrics yielded a model efficiency (Mef) ranging from 0.31 to 0.46, with a RMSE ranging from 14.13 to 32.16 Mg/ha and rRMSE from 38.17 to 84.74%, at GEDI footprint level by forest type. The impact of forest structure confirmed previous studies achievements, since GEDI data showed higher uncertainty in highly multilayered forests. In general, GEDI-derived models (GEDI-like Level4A) underestimated AGB over lower and higher ALS-derived AGB intervals. The proposed models could also be used to monitor biomass stocks at large-scale by using GEDI footprint level in Mediterranean areas, especially in remote and hard-to-reach areas for forest inventory. The findings from this study serve to provide an initial evaluation of GEDI data for estimating AGB in Mediterranean forestSIExtremadura Forest ServiceFundação para a Ciência e a Tecnologia I.P. (FCT), Portuga

Clinical trial evaluating the effectiveness of biocompound IMMUNEPOTENT CRP in the third-molar extraction

ABSTRACT A controlled, parallel, randomized and comparative trial was carried out to evaluate the antiinflammatory efficacy of IMMUNEPOTENT CRP versus ibuprofen in patients after third-molar surgery over seven days. The anti-inflammatory efficacy of IMMUNEPOTENT CRP was evaluated using the method of Amin and Laskin, and the analysis of cytokine production (IL-2, IL-4, IL-6, IL-10, TNF-a, INF-g) in saliva was done by flow cytometry. The swelling process after surgery was significant (p < 0.05) and the treatments with IMMUNEPOTENT CRP or ibuprofen controlled this process properly; no difference between the groups was found (p < 0.05). Both treatments were shown to modulate the cytokine production. These results demonstrate the anti-inflammatory activity of the natural compound IMMUNEPOTENT CRP and suggest it could be used in clinical dental practice

Improving zebrafish embryo xenotransplantation conditions by increasing incubation temperature and establishing a proliferation index with ZFtool

Background Zebrafish (Danio rerio) is a model organism that has emerged as a tool for cancer research, cancer being the second most common cause of death after cardiovascular disease for humans in the developed world. Zebrafish is a useful model for xenotransplantation of human cancer cells and toxicity studies of different chemotherapeutic compounds in vivo. Compared to the murine model, the zebrafish model is faster, can be screened using high-throughput methods and has a lower maintenance cost, making it possible and affordable to create personalized therapies. While several methods for cell proliferation determination based on image acquisition and quantification have been developed, some drawbacks still remain. In the xenotransplantation technique, quantification of cellular proliferation in vivo is critical to standardize the process for future preclinical applications of the model. Methods This study improved the conditions of the xenotransplantation technique – quantification of cellular proliferation in vivo was performed through image processing with our ZFtool software and optimization of temperature in order to standardize the process for a future preclinical applications. ZFtool was developed to establish a base threshold that eliminates embryo auto-fluorescence and measures the area of marked cells (GFP) and the intensity of those cells to define a ‘proliferation index’. Results The analysis of tumor cell proliferation at different temperatures (34 °C and 36 °C) in comparison to in vitro cell proliferation provides of a better proliferation rate, achieved as expected at 36°, a maintenance temperature not demonstrated up to now. The mortality of the embryos remained between 5% and 15%. 5- Fluorouracil was tested for 2 days, dissolved in the incubation medium, in order to quantify the reduction of the tumor mass injected. In almost all of the embryos incubated at 36 °C and incubated with 5-Fluorouracil, there was a significant tumor cell reduction compared with the control group. This was not the case at 34 °C. Conclusions Our results demonstrate that the proliferation of the injected cells is better at 36 °C and that this temperature is the most suitable for testing chemotherapeutic drugs like the 5-FluorouracilThis research was funded by the Fondo de Investigación Sanitaria (Instituto Carlos III) - FIS project (PI13/01388). The funding body had no role in the design of the study and collection, analysis, and interpretation of data and in writing of this manuscriptS

GHIA (Grupo de Herramientas Interactivas Avanzadas)

Es este documento se resumen las principales líneas actuales de investigación del grupo GHIA en lo que a informática educativa se refiere, así como su contexto y proyectos de futuro.This document summarizes the main research areas of GHIA regarding computer based learning, as well as its context and future work.En el momento actual, agradecemos su apoyo a los proyectos ASIES (TIN2010-17344) y Go-Lite (TIN2011-24139), financiados por el Ministerio de Educación, y al proyecto e-Madrid (S2009/TIC-1650), financiado por la Comunidad Autónoma de Madrid

Soft balancing in the Americas : Latin American opposition to U.S. intervention, 1898–1936

In the aftermath of the 2003 U.S.-led invasion of Iraq, scholars of international relations debated how to best characterize the rising tide of global opposition. The concept of “soft balancing” emerged as an influential, though contested, explanation of a new phenomenon in a unipolar world: states seeking to constrain the ability of the United States to deploy military force by using multinational organizations, international law, and coalition building. Soft balancing can also be observed in regional unipolar systems. Multinational archival research reveals how Argentina, Mexico, and other Latin American countries responded to expanding U.S. power and military assertiveness in the early twentieth century through coordinated diplomatic maneuvering that provides a strong example of soft balancing. Examination of this earlier case makes an empirical contribution to the emerging soft-balancing literature and suggests that soft balancing need not lead to hard balancing or open conflict

Aproximación a la simulación de un sistema de telefonía móvil celular

En este artículo se describe un módulo de prácticas diseñado para los alumnos de primer curso de Ingeniería Técnica de Telecomunicación de la ULPGC en el que se simulan ciertos aspectos de un sistema de telefonía móvil celular (STMC). Los principales objetivos que se han perseguido son presentar a los alumnos la programación de computadores como una disciplina claramente relevante dentro del ámbito de las telecomunicaciones, y al mismo tiempo favorecer que los alumnos puedan ir descubriendo las conexiones que existen entre las distintas materias del plan de estudios desde los primeros cursos

Antitumor activity of colloidal silver on MCF-7 human breast cancer cells

<p>Abstract</p> <p>Background</p> <p>Colloidal silver has been used as an antimicrobial and disinfectant agent. However, there is scarce information on its antitumor potential. The aim of this study was to determine if colloidal silver had cytotoxic effects on MCF-7 breast cancer cells and its mechanism of cell death.</p> <p>Methods</p> <p>MCF-7 breast cancer cells were treated with colloidal silver (ranged from 1.75 to 17.5 ng/mL) for 5 h at 37°C and 5% CO₂atmosphere. Cell Viability was evaluated by trypan blue exclusion method and the mechanism of cell death through detection of mono-oligonucleosomes using an ELISA kit and TUNEL assay. The production of NO, LDH, and Gpx, SOD, CAT, and Total antioxidant activities were evaluated by colorimetric assays.</p> <p>Results</p> <p>Colloidal silver had dose-dependent cytotoxic effect in MCF-7 breast cancer cells through induction of apoptosis, shown an LD₅₀(3.5 ng/mL) and LD₁₀₀(14 ng/mL) (*P < 0.05), significantly decreased LDH (*P < 0.05) and significantly increased SOD (*P < 0.05) activities. However, the NO production, and Gpx, CAT, and Total antioxidant activities were not affected in MCF-7 breast cancer cells. PBMC were not altered by colloidal silver.</p> <p>Conclusions</p> <p>The present results showed that colloidal silver might be a potential alternative agent for human breast cancer therapy.</p