The Story of the Puerto Rican-Chicano Committee

The concept or idea for The Puerto Rican-Chicano Committee (PRCC) came from UB student Alberto O. Cappas, who also was the original founder of PODER, at the time known as the Puerto Rican Organization for Dignity, Elevation, and Responsibility

Cultura da cidadão: Arquitetura, cidade e crianças. Experiências em San Jose, Costa Rica

Tener ciudades humanizadas con calidad de vida para todos depende, definitivamente de proponer un cambio en los niños y jóvenes desde el inicio a través de los procesos educativos, utilizando nuevas formas de aprender de una manera lúdica y participativa. Este artículo presenta talleres realizados en San José, Costa Rica: en escuela pública, escuela privada y espacio público. Actividades que permiten identificar los aportes de esta población en las soluciones sostenibles de las ciudades con base en lo compartido y aprendido en los talleres. Se concluye que los conocimientos adquiridos se asimilaron, generando opinión, sentido crítico y creativo al respectoTo have humanized cities with quality of life for all depends on the change of children and young people through educational processes, using new ways to learn in a playful and participative way. This article presents workshops held in San José, Costa Rica: in public school, private school and public space. Activities that allow the identification of the contributions of this population in the sustainable solutions of the cities based on the shared and learned in the workshops. In conclusion, the acquired knowledge was assimilated and it generated opinion, critical and creative sense in this respectTer cidades humanizados com qualidade de vida para todos passa pela proposta de uma alteração, desde cedo, dos processos educacionais nas crianças e nos jovens, utilizando novas formas de aprendizagem divertidas e participativas. Este artigo apresenta workshops realizados em San Jose, Costa Rica: nas escolas públicas, escolas particulares e em espaço público. Atividades que permitem identificar as contribuições da população das cidades com base na partilha e a aprendizagem nas oficinas. Conclui-se que o conhecimento adquirido foi assimilado, criando opiniões e pensamento crítico e criativo nesse âmbit

Corporate Entrepreneurship: Building a Knowledge-Based View of the Firm

Increasing globalisation and dynamism in the economy has made it necessary for established companies to regenerate themselves and renew their ability to compete. This is the goal of Corporate Entrepreneurship (CE) activities, which involve extending the firm’s domain of competence and corresponding opportunity set, through internally generated new resource combinations. The purpose of this study is to contribute to the understanding of the way the process of CE is developed within the organizations. In order to achieve this, a model relating key components of the CE process (opportunity, initiative and capability) to five phases of knowledge creation taken from Nonaka & Takeuchi is proponed.organizational knowledge creation; corporate entrepreneurship; knowledge-base view; innovation; development of capabilities

Human metapneumovirus: Mechanisms and molecular targets used by the virus to avoid the immune system

Indexación: Scopus.This work was supported by Comisión Nacional de Investigación Científica y Tecnolígica (CONICYT) N◦21151028 and FONDECYT (N◦1070352 and N◦1170964) and the Millennium Institute on Immunology and Immunotherapy (P09/016-F).Human metapneumovirus (hMPV) is a respiratory virus, first reported the year 2001. Since then, it has been described as one of the main etiological agents that causes acute lower respiratory tract infections (ALRTIs), which is characterized by symptoms such as bronchiolitis, wheezing and coughing. Susceptible population to hMPV-infection includes newborn, children, elderly and immunocompromised individuals. This viral agent is a negative-sense, single-stranded RNA enveloped virus, that belongs to the Pneumoviridae family and Metapneumovirus genus. Early reports-previous to 2001-state several cases of respiratory illness without clear identification of the responsible pathogen, which could be related to hMPV. Despite the similarities of hMPV with several other viruses, such as the human respiratory syncytial virus or influenza virus, mechanisms used by hMPV to avoid the host immune system are still unclear. In fact, evidence indicates that hMPV induces a poor innate immune response, thereby affecting the adaptive immunity. Among these mechanisms, is the promotion of an anergic state in T cells, instead of an effective polarization or activation, which could be induced by low levels of cytokine secretion. Further, the evidences support the notion that hMPV interferes with several pattern recognition receptors (PRRs) and cell signaling pathways triggered by interferon-associated genes. However, these mechanisms reported in hMPV are not like the ones reported for hRSV, as the latter has two non-structural proteins that are able to inhibit these pathways. Several reports suggest that viral glycoproteins, such as G and SH, could play immune-modulator roles during infection. In this work, we discuss the state of the art regarding the mechanisms that underlie the poor immunity elicited by hMPV. Importantly, these mechanisms will be compared with those elicited by other common respiratory viruses. © 2018 Frontiers Media S.A. All rights reserved.https://www.frontiersin.org/articles/10.3389/fimmu.2018.02466/ful

Synthesis, physicochemical and photophysical characterization of 4-(1-Pyrenyl)-Butyl-α-d-mannopyranoside

Indexación: Web of Science; Scopus; Scielo.Glycolipids are biomolecules composed of a lipid chain (lipophilic) and a monosaccharide or oligosaccharide as hydrophilic group. Their chemical structure and biological role make them undoubtedly good candidates for a large and continuously growing number of biotechnological applications. Mannose is a carbohydrate present on membrane glycolipids of a wide number of pathogenic microorganisms (bacteria, fungi, protozoa, and viruses) and specifically recognized by several lectins. We synthesized a mannose derivative linked through a short methylene chain to a pyrene moiety which behaves as a surfactant, able to aggregate, and retains the photophysical properties of pyrene: showing comparable absorption and emission spectra, having lower fluorescence quantum yield and the ability to form excimer, and finally the ability to produce O-2((1)Delta(g)) with high quantum yields. Thus, this novel molecule would open future applications for detection (fluorescence) or inactivation (singlet oxygen) of bacterial pathogens, viruses, tumor cells, or particular cells.http://ref.scielo.org/pcn4d

El valor de la demostración en la educación secundaria

A lo largo de la licenciatura de Matemáticas (que terminamos el curso pasado), el rigor ha sido la característica predominante: siempre se ha demostrado todo lo afirmado o utilizado. Este hecho hizo que no concibiéramos unas matemáticas sin demostraciones. Con este enfoque de las matemáticas iniciamos nuestro periodo de prácticas (correspondientes a la asignatura "Prácticas de la Enseñanza" de quinto curso) y nos enfrentamos por primera vez con la realidad educativa: no todo lo que se le explica a los alumnos debe ser objeto de demostración. Mediante esta comunicación pretendemos compartir nuestras reflexiones sobre el valor de la demostración en las matemáticas de la Enseñanza Secundaria

Análisis del cumplimiento tributarío, la gestión y control de las cuentas de gastos de una empresa que produce y comercializa fundas y zunchos para banano ubicada en el cantón Pascuales durante el ejercicio fiscal 2008

The main intention of this tesina is to verify that the company has fulfilled suitably the tributary obligations, having correctly provisionado the risks derived from possible fiscal contingencies. In order to fulfill the proposed objective one took place the planning, programming and application of the audit tests, the same ones that helped us to the Service to the revision of the tributary declarations presented/displayed by the company of Internal Rents and to be able to determine the consistency of this information. Soon we elaborated necessary the internal controls for each test of audit that we carried out, with the intention that the company can have a suitable tributary fulfillment

3D Printed Robotic Hand

Dexterous robotic hands are changing the way robots and humans interact and use common tools. Unfortunately, the complexity of the joints and actuations drive up the manufacturing cost. Some cutting edge and commercially available rapid prototyping machines now have the ability to print multiple materials and even combine these materials in the same job. A 3D model of a robotic hand was designed using Creo Parametric 2.0. Combining "hard" and "soft" materials, the model was printed on the Object Connex350 3D printer with the purpose of resembling as much as possible the human appearance and mobility of a real hand while needing no assembly. After printing the prototype, strings where installed as actuators to test mobility. Based on printing materials, the manufacturing cost of the hand was $167, significantly lower than other robotic hands without the actuators since they have more complex assembly processes