2,878 research outputs found
CISTO TRAUMÁTICO DA MANDÍBULA- RELATO DE CASO CLÍNICO
O cisto ósseo traumático é uma lesão não neoplásica que representa aproximadamente 1% de todos os cistos maxilares, acometendo as regiões de corpo e sínfise de mandíbula com maior freqüência. Sua etiologia é desconhecida, mas acredita-se que o trauma local seja fator relacionado ao seu desenvolvimento. Não há predileção por sexo e afeta mais jovens abaixo de 25 anos. O diagnóstico pode ser por radiografias de rotina que apresentam lesão radiolúcida, uniradicular, de crescimento lento, tamanho variável e limites definidos. O tratamento é cirúrgico com curetagem e punção
Stereology shows that damaged liver recovers after protein refeeding
Objective: The aim of the present study was to investigate the putative effects of a low-protein diet on the three-dimensional structure of hepatocytes and determine whether this scenario could be reversed by restoring the adequate levels of protein to the diet. Methods: Using design-based stereology, the total number and volume of hepatocytes were estimated in the liver of mice in healthy and altered (by protein malnutrition) conditions and after protein renutrition. Results: This study demonstrated a 65% decrease in the liver volume (3302 mm3 for the control for undernourished versus 1141 mm3 for the undernourished group) accompanied by a 46% reduction in the hepatocyte volume (8223 μm3 for the control for undernourished versus 4475 μm3 for the undernourished group) and a 90% increase in the total number of binucleate hepatocytes (1 549 393 for the control for undernourished versus 2 941 353 for the undernourished group). Reinstating a normoproteinic diet (12% casein) proved to be effective in restoring the size of hepatocytes, leading to an 85% increase in the total number of uninucleate hepatocytes (15 988 560 for the undernourished versus 29 600 520 for the renourished group), and partially reversed the liver atrophy. Conclusions: Awareness of these data will add to a better morphologic understanding of malnutrition-induced hepatopathies and will help clinicians improve the diagnosis and treatment of this condition in humans and in veterinary practice
The Effect of a Linear Tuning between the Antigenic Stimulations of CD4(+) T Cells and CD4(+) Tregs
We study the equilibria of an Ordinary Differencial Equation (ODE) system where CD4+ effector or helper T cells and Regulatory T cells (Tregs) are present. T cells trigger an immune response in the presence of their specific antigen. Regulatory T cells (Tregs) play a role in limiting auto-immune diseases due to their immune-suppressive ability. Here, we present explicit exact formulas that give the relationship between the concentration of T cells, the concentration of Tregs, and the antigenic stimulation of T cells, when the system is at equilibria, stable or unstable. We found a parameter region of bistability, limited by two thresholds of antigenic stimulation of T cells (hysteresis). Moreover, there are values of the slope parameter of the tuning for which an isola-center bifurcation appears, and, for some other values, there is a transcritical bifurcation. We also present time evolutions of the ODE system
Serosurvey of selected avian pathogens in brazilian commercial Rheas (Rhea americana) and Ostriches (Struthio camelus)
Ratite farming of has expanded worldwide. Due to the intensive farming methods used by ratite producers, preventive medicine practices should be established. In this context, the surveillance and control of some avian pathogens are essential for the success of the ratite industry; however, little is known on the health status of ratites in Brazil. Therefore, the prevalence of antibodies against Newcastle Disease virus, Chlamydophila psittaci, Mycoplasma gallisepticum, Mycoplasma synoviae, and Salmonella Pullorum were evaluated in 100 serum samples collected from commercial ostriches and in 80 serum samples from commercial rheas reared in Brazil. All sampled animals were clinically healthy. The results showed that all ostriches and rheas were serologically negative to Newcastle disease virus, Chlamydophila psittaci, Mycoplasma gallisepticum, and Mycoplasma synoviae. Positive antibody responses against Salmonella Pullorum antigen were not detected in ostrich sera, but were detected in two rhea serum samples. These results can be considered as a warning as to the presence of Salmonella spp. in ratite farms. Therefore, the implementation of good health management and surveillance programs in ratite farms may contribute to improve not only animal production, but also public health conditions.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvi-mento Científico e Tecnológico (CNPq
An iterative algorithm for parametrization of shortest length shift registers over finite rings
The construction of shortest feedback shift registers for a finite sequence
S_1,...,S_N is considered over the finite ring Z_{p^r}. A novel algorithm is
presented that yields a parametrization of all shortest feedback shift
registers for the sequence of numbers S_1,...,S_N, thus solving an open problem
in the literature. The algorithm iteratively processes each number, starting
with S_1, and constructs at each step a particular type of minimal Gr\"obner
basis. The construction involves a simple update rule at each step which leads
to computational efficiency. It is shown that the algorithm simultaneously
computes a similar parametrization for the reciprocal sequence S_N,...,S_1.Comment: Submitte
R&D DYNAMICS
We study a Cournot duopoly model using Ferreira-Oliveira-Pinto's R&D investment function. We find the multiple perfect Nash equilibria and we analyse the economical relevant quantities like output levels, prices, consumer surplus, profits and welfare
Stellar Coronal and Wind Models: Impact on Exoplanets
Surface magnetism is believed to be the main driver of coronal heating and
stellar wind acceleration. Coronae are believed to be formed by plasma confined
in closed magnetic coronal loops of the stars, with winds mainly originating in
open magnetic field line regions. In this Chapter, we review some basic
properties of stellar coronae and winds and present some existing models. In
the last part of this Chapter, we discuss the effects of coronal winds on
exoplanets.Comment: Chapter published in the "Handbook of Exoplanets", Editors in Chief:
Juan Antonio Belmonte and Hans Deeg, Section Editor: Nuccio Lanza. Springer
Reference Work
Studies on the interaction of the carbohydrate binding module 3 from the Clostridium thermocellum CipA scaffolding protein with cellulose and paper fibres
The adsorption of a carbohydrate binding module (CBM3) from the Clostridium thermocellum scaffolding protein (CipA) to cellulose was analysed in this work. The effect of CBM-PEG on the drainability of E. globulus and P. sylvestris pulps and on the physical properties of the respective papersheets was also studied. The CBM binding to cellulose is often described as “irreversible”, but this classification does not fully characterize this interaction. Indeed, the results obtained demonstrate that, although the adsorption on cellulose is rather stable, CBM inter-fibre mobility may be observed. The results also showed that the CBM-PEG conjugate improves the drainability of E. globulus and P. sylvestris pulps without affecting the physical properties of the papersheets.This research was supported by Fundacao para a Ciencia e a Tecnologia under grant POCTI/BIO/45356/2002
Dynamic clamp with StdpC software
Dynamic clamp is a powerful method that allows the introduction of artificial electrical components into target cells to simulate ionic conductances and synaptic inputs. This method is based on a fast cycle of measuring the membrane potential of a cell, calculating the current of a desired simulated component using an appropriate model and injecting this current into the cell. Here we present a dynamic clamp protocol using free, fully integrated, open-source software (StdpC, for spike timing-dependent plasticity clamp). Use of this protocol does not require specialist hardware, costly commercial software, experience in real-time operating systems or a strong programming background. The software enables the configuration and operation of a wide range of complex and fully automated dynamic clamp experiments through an intuitive and powerful interface with a minimal initial lead time of a few hours. After initial configuration, experimental results can be generated within minutes of establishing cell recording
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