Segurança do paciente e a pandemia da COVID-19: uma reflexão de enfermagem

O tema segurança do paciente está inserido em um contexto transversal, que deve ser abordado e praticado pelos profissionais de saúde, em sua vasta rede de atuação. Com a chegada da pandemia ocasionada pelo novo coronavírus, então chamado de Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)  o qual provoca a doença COVID-19 (Corona Virus Disease), questionamentos sobre as medidas de contingenciamento e o uso de equipamentos de proteção individual (EPI) emergiram e inquietaram docentes e discentes de graduação e da Residência de Enfermagem com ênfase em Cardiologia nos diferentes cenários de atuação. A pandemia causada pelo novo coronavírus se tornou um grave e emergencial problema de saúde pública no mundo (LIPSITCH; SWERDLOW; FINELLI, 2020; ROTHAN; BYRAREDDY, 2020). Os impactos à saúde e demais dimensões da vida das pessoas ainda são subestimados; porém, as consequências já são devastadoras e preocupantes no curso do tempo

In silico studies on leishmanicide activity of limonoids and fatty acids from Carapa guianensis Aubl

The oil of Carapa guianensis showed leishmanicidal activity, with its activity being related to limonoids, but fatty acids are the major constituents of this oil. The present study evaluated the physicochemical, pharmacokinetic, and toxicity profiles of limonoids and fatty acids already identified in the species. Based on these results, 2 limonoids (methyl angosinlate, 6-OH-methyl angosinlate) and 2 fatty acids (arachidic acid; myristic acid) were selected for the prediction of possible targets and molecular docking. Included in this study were: Gedunin, 6α-acetoxygedunin, Methyl angosenlato, 7-deacetoxy-7-oxogedunin, Andirobin, 6-hydroxy-angolensate methyl, 17β-hydroxyazadiradione, 1,2-dihydro-3β-hydroxy-7-deacetoxy-7-oxogedunin, xyllocensin k, 11beta-Hydroxygedunin, 6α,11-11β-diacetoxygedunin, Oleic Acid, Palmitic Acid, Stearic Acid, Arachidic Acid, Myristic Acid, Palmitoleic Acid, Linoleic Acid, Linolenic Acid, and Beenic Acid. Regarding physicochemical aspects, fatty acids violated LogP, and only limonoid 11 violated Lipinski’s rule. A common pharmacokinetic aspect was that all molecules were well absorbed in the intestine and inhibited CYP. All compounds showed toxicity in some model, with fatty acids being mutagenic and carcinogenic, and limonoids not being mutagenic and carcinogenic at least for rats. In in vivo models, fatty acids were less toxic. Molecular dockings were performed on COX-2 steroids (15 and 16) and hypoxia-inducible factor 1 alpha for limonoids (3,6), with this target being essential for the intracellular development of leishmania. Limonoids 3 and 6 appear to be promising as leishmanicidal agents, and fatty acids are promising as wound healers

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Análise de agrotóxicos em água usando extração líquido-líquido com partição em baixa temperatura por cromatografia líquida de alta eficiência

This study optimized and validated the liquid-liquid extraction technique with partition at low temperature (LLE-PLT) for identification and quantification of four pesticides (chlorpyrifos, λ-cyhalothrin, permethrin, bifenthrin) in water samples. Analyses were performed by HPLC-UV. The technique was efficient for pesticide recovery with extraction exceeding 86%. Chromatographic response was linear for the four compounds in the 10-45 µg L-1 range, with correlation coefficients greater than 0.99. Limits of detection and quantitation were less than 3.5 µg L-1 and equal to 10 µg L-1, respectively. The proposed method was applied to 29 water samples from the Jaíba Project in northern Minas Gerais

Aptidão física em adolescentes praticantes de Futebol

Physical fitness of youth that practice footballThis study aimed to identify the level of physical fitness of football practitioners, aged between 8 to 12 years, from the city of Jaraguá GO. The sample consisted of 94 football students, divided into sub 11, sub 13 and sub 15 categories. For statistical analysis, the PROESP BR test protocol was used to verify the normality of the data. A significance level of P = 0.005 was adopted using SPSS20.0 software. The results achieved were lower than expected, since in the variables BMI, weight, flexibility and cardiorespiratory capacity, the sub 11, sub 13 and sub 15 categories were found at the same levels and, in the variables of agility, speed, resistance and limb strength Lower and higher, all categories match. With the results obtained, it was possible to conclude that the categories are in the same level of physical fitness, noting that the levels of physical fitness of football practitioners are below the recommended average for good health in all categories.Este estudo teve como objetivo identificar o nível de aptidão física dos praticantes de futebol, entre 8 a 12 anos, da cidade de Jaraguá GO. A amostra foi constituída de 94 atletas praticantes de futebol divididos em categorias sub 11, sub 13 e sub 15. Para análise estatística, foi utilizado, para verificar a normalidade dos dados, o protocolo de teste da PROESP BR. Adotou-se um nível de significância de P= 0,005 por meio do software SPSS20.0. Os resultados alcançados foram abaixo do esperado, pois nas variáveis de IMC, peso, flexibilidade e capacidade cardiorrespiratória as categorias sub 11, sub 13 e sub 15 se encontram, nos mesmos níveis e, nas variáveis de agilidade, velocidade, resistência e força de membros inferiores e superiores, todas as categorias se igualam.  Com os resultados obtidos, pôde se concluir que as categorias estão no mesmo nível de aptidão física, notando-se que os níveis de aptidão física dos praticantes de futebol estão abaixo da média do recomendável para uma boa saúde em todas as categorias.

2nd Meeting for Accessibility and Inclusion in Art and Heritage : book proceedings

Obra publicada por ocasião do Segundo Encontro de Acessibilidade e Inclusão na Arte e no Património, decorrido nos dias 24 e 25 de junho de 2022 Resumo2ª edição do encontro Acessibilidade e Inclusão na Arte e no Património é uma iniciativa da Faculdade de Belas-Artes da Universidade de Lisboa e do Museu da Farmácia. Tem como objetivo ser um espaço de discussão e troca de ideias, reunindo trabalhos associados à acessibilidade à arte e ao património cultural. Divulgando estratégias que visam melhorar o acesso e a inclusão dos diversos públicos, nomeadamente de públicos com deficiência, ao património. Este livro de atas reúne nove artigos. São abordados temas associados à teoria e legislação sobre acessibilidade e inclusão no património; avaliação da acessibilidade nos museus; experiências multissensoriais em museus e monumentos e ainda o desenvolvimento de produtos que promovam acessibilidade em museus. O Encontro contou com a participação de investigadores e profissionais da área provenientes de várias instituições nacionais e internacionaisinfo:eu-repo/semantics/publishedVersio

Seminário de Dissertação (2024)

Página da disciplina de Seminário de Dissertação (MPPP, UFPE, 2022) Lista de participantes == https://docs.google.com/spreadsheets/d/1mrULe1y04yPxHUBaF50jhaM1OY8QYJ3zva4N4yvm198/edit#gid=