Domestic violence in the Ancient Egypt

Los relatos mitológicos, los textos literarios, los documentos legales y algunos estudios paleopatológicos demuestran que la violencia doméstica fue una constante de la vida en el Egipto antiguo. A pesar de que gozaba de igualdad legal con respecto al hombre y de que en los textos literarios siempre aparece como la generadora de la violencia doméstica, en realidad fue la mujer quien la sufrió con mayor asiduidad, como nos muestra la documentación existente.Mythological narratives, literary texts, legal documents, forensic testimonies and some paleopathological studies prove that gender violence was a constant in ancient Egyptian daily life. However, despite the fact that Egyptian women had legal equality with men and despite evidence in literary texts, where women always appears as the instigators of domestic gender violence, Egyptian women suffered that violence with more regularity than men, as proved by documentary evidence

¿Qué factores del modelo de negocio hacen a las PYMEs más rentable?

[ENG] The aim of this article is to detect the business model factors that increase firm performance. To carry out this research, a survey was conducted among the CEOs of seventy companies in the Region of Murcia, Spain, belonging to different sectors of economic activity. The empirical evidence obtained indicates that the characteristics of a company's business model affect its performance and future viability. In this sense, the article confirms that the business model factors that contribute to improving the future viability of a firm are mainly innovation, professionalization of the economic-financial area, investment in employees, and strengthening of the commercial area. Therefore, firms that wish to improve their long-term performance should especially strengthen these characteristics of the business model. [SPA] El objetivo de este artículo es detectar los factores del modelo de negocio que incrementan el rendimiento de las empresas. Para llevar a cabo esta investigación, se realizó una encuesta entre los directores generales de setenta empresas de la Región de Murcia, España, pertenecientes a diferentes sectores de actividad económica. La evidencia empírica obtenida indica que las características del modelo de negocio de una empresa afectan a su rendimiento y viabilidad futura. En este sentido, el artículo confirma que los factores del modelo de negocio que contribuyen a mejorar la viabilidad futura de una empresa son principalmente la innovación, la profesionalización del área económico-financiera, la inversión en empleados y la potenciación del área comercial. Por lo tanto, las empresas que deseen mejorar sus resultados a largo plazo deberían reforzar especialmente estas características del modelo de negocio.I would like to thank all the entrepreneurs in the Region of Murcia who have participated in this work, by contributing with their energy and knowledge

SISTEMA WEB DE APOYO A LA DOCENCIA, AL APRENDIZAJE Y A LA GESTIÓN DE DATOS ACADÉMICOS DE ASIGNATURAS UNIVERSITARIAS

 RESUMEN En este artículo se propone un modelo jerárquico de roles de usuario para el diseño de sistemas Web que permite un diseño estructurado de la interfaz de usuario, una mejor adaptabilidad al perfil del usuario y la simplificación de la especificación de tareas del sistema. Dicho modelo ha sido aplicado al desarrollo de un sistema Web, denominado Tutor, que da soporte a la docencia, al aprendizaje y a la gestión de datos académicos (de alumnos, profesores, titulaciones, etc.) relacionados con asignaturas de la Universidad de Granada. El equipo de desarrollo ha estado formado por profesores, estudiantes y técnicos de los servicios de informática y redes de comunicaciones de dicha universidad, por lo que desde el principio se ha tenido presente la finalidad pedagógica de cada utilidad a la hora de incluirla en el sistema. El sistema implementado ofrece una serie de servicios electrónicos, siendo algunos de ellos de acceso libre, mientras que otros son de acceso restringido sólo a usuarios registrados en el sistema (cuando se requiere proteger la privacidad de los datos). La principal finalidad de nuestro sistema consiste en lograr algunos de los objetivos establecidos en el contexto del Espacio Europeo de Educación Superior, que fija y unifica los criterios de calidad que deben cumplir los estudios superiores en los estados miembros.  PALABRAS CLAVESSistema Web de Apoyo a la DocenciaSistema Web de Soporte al AprendizajeTecnologías de la Información y la Comunicación (TIC)Aplicadas a la EducaciónInnovación Docente  ABSTRACT In this paper, we propose a hierarchical model of user roles to be applied in the development of Web-based applications. The model facilitates a structured design of user interfaces, a better adaptability to user profiles and the simplification of the specification of system tasks. This model has been applied to the development of a Web-based system, called Tutor, that provides support for teaching and learning some subjects taught at the University of Granada, and for the management of academic data (of students, teachers, degrees, etc.) related with these subjects. The development team is made up of teachers, students and technicians of computer science and communication network services belonging to this university. For that reason, we have always had in mind the pedagogic purpose of each utility included in the system. The implemented system offers a series of electronic services, some of them are free access, while others are restricted access only to users registered in the system (when data privacy protection is required). The main aim of our system is to achieve some of the objectives established in the context of the European Space of Higher Education, which sets and unifies quality criteria that the higher studies within its member states must satisfy.  KEYWORDSWeb-Based Teaching-Support SystemWeb-Based Learning-Support SystemInformation and Communication Technologies Appliedto EducationTeaching Innovation

SISTEMA WEB DE APOYO A LA DOCENCIA, AL APRENDIZAJE Y A LA GESTIÓN DE DATOS ACADÉMICOS DE ASIGNATURAS UNIVERSITARIAS

 RESUMEN En este artículo se propone un modelo jerárquico de roles de usuario para el diseño de sistemas Web que permite un diseño estructurado de la interfaz de usuario, una mejor adaptabilidad al perfil del usuario y la simplificación de la especificación de tareas del sistema. Dicho modelo ha sido aplicado al desarrollo de un sistema Web, denominado Tutor, que da soporte a la docencia, al aprendizaje y a la gestión de datos académicos (de alumnos, profesores, titulaciones, etc.) relacionados con asignaturas de la Universidad de Granada. El equipo de desarrollo ha estado formado por profesores, estudiantes y técnicos de los servicios de informática y redes de comunicaciones de dicha universidad, por lo que desde el principio se ha tenido presente la finalidad pedagógica de cada utilidad a la hora de incluirla en el sistema. El sistema implementado ofrece una serie de servicios electrónicos, siendo algunos de ellos de acceso libre, mientras que otros son de acceso restringido sólo a usuarios registrados en el sistema (cuando se requiere proteger la privacidad de los datos). La principal finalidad de nuestro sistema consiste en lograr algunos de los objetivos establecidos en el contexto del Espacio Europeo de Educación Superior, que fija y unifica los criterios de calidad que deben cumplir los estudios superiores en los estados miembros.  PALABRAS CLAVESSistema Web de Apoyo a la DocenciaSistema Web de Soporte al AprendizajeTecnologías de la Información y la Comunicación (TIC)Aplicadas a la EducaciónInnovación Docente  ABSTRACT In this paper, we propose a hierarchical model of user roles to be applied in the development of Web-based applications. The model facilitates a structured design of user interfaces, a better adaptability to user profiles and the simplification of the specification of system tasks. This model has been applied to the development of a Web-based system, called Tutor, that provides support for teaching and learning some subjects taught at the University of Granada, and for the management of academic data (of students, teachers, degrees, etc.) related with these subjects. The development team is made up of teachers, students and technicians of computer science and communication network services belonging to this university. For that reason, we have always had in mind the pedagogic purpose of each utility included in the system. The implemented system offers a series of electronic services, some of them are free access, while others are restricted access only to users registered in the system (when data privacy protection is required). The main aim of our system is to achieve some of the objectives established in the context of the European Space of Higher Education, which sets and unifies quality criteria that the higher studies within its member states must satisfy.  KEYWORDSWeb-Based Teaching-Support SystemWeb-Based Learning-Support SystemInformation and Communication Technologies Appliedto EducationTeaching Innovation

Vitamin D levels in the pre- and post-COVID-19 pandemic periods in pediatric patients with chronic kidney disease

IntroductionVitamin D (VD) deficiency is common in children with chronic kidney disease (CKD) because of multiple factors. During the coronavirus disease 2019 (COVID-19) pandemic, it increased because of medicine shortage and no enough medical service for patients with non-COVID-19 diseases.ObjectiveTo analyze the effects of the COVID-19 pandemic-related lockdown on the serum levels and status of 25-hydroxyvitamin D3 (25-[OH]D) in children with CKD.Materials and methodsThis retrospective study included patients (6–18 years old) who were diagnosed with CKD stage 2–5 and routinely measured for serum VD levels between May 2019 and December 2022. Serum 25-(OH)D levels were measured before, during, and after the pandemic (2019, 2020–2021, and 2022, respectively). The daily dose of cholecalciferol supplementation and the readjustment (if required) were recorded.ResultsThis study included 171 patients (median age: 12 years). Before the pandemic, the median serum VD level was 25.0 ng/mL (19.3% VD deficiency). Then, VD supplementation was adjusted to 400–1,200 UI daily in 98.8% (n = 169) of patients. During the pandemic, the median VD level decreased to 22.5 ng/mL (43.3% VD deficiency). Hence, the supplementation was readjusted, and after the pandemic, the level was 28.7 ng/mL (18.7% VD deficiency), indicating a statistically significant increase in serum VD levels from the prepandemic period (p = 0.007).ConclusionDecreased serum VD levels and increased VD deficiency frequency were observed in patients with CKD during the COVID-19 but improved after readjustment of supplementation

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Anti-Spike antibodies 3 months after SARS-CoV-2 mRNA vaccine booster dose in patients on hemodialysis: the prospective SENCOVAC study

Background: Patients on hemodialysis are at high-risk for complications derived from coronavirus disease 2019 (COVID-19). The present analysis evaluated the impact of a booster vaccine dose and breakthrough severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on humoral immunity 3 months after the booster dose. Methods: This is a multicentric and prospective study assessing immunoglobulin G anti-Spike antibodies 6 and 9 months after initial SARS-CoV-2 vaccination in patients on hemodialysis that had also received a booster dose before the 6-month assessment (early booster) or between the 6- and 9-month assessments (late booster). The impact of breakthrough infections, type of vaccine, time from the booster and clinical variables were assessed. Results: A total of 711 patients [67% male, median age (range) 67 (20-89) years] were included. Of these, 545 (77%) received an early booster and the rest a late booster. At 6 months, 64 (9%) patients had negative anti-Spike antibody titers (3% of early booster and 29% of late booster patients, P =. 001). At 9 months, 91% of patients with 6-month negative response had seroconverted and there were no differences in residual prevalence of negative humoral response between early and late booster patients (0.9% vs 0.6%, P =. 693). During follow-up, 35 patients (5%) developed breakthrough SARS-CoV-2 infection. Antibody titers at 9 months were independently associated with mRNA-1273 booster (P =. 001), lower time from booster (P =. 043) and past breakthrough SARS-CoV-2 infection (P <. 001). Conclusions: In hemodialysis patients, higher titers of anti-Spike antibodies at 9 months were associated with mRNA-1273 booster, lower time from booster and past breakthrough SARS-CoV-2 infectionThe present project has been supported by Fresenius Medical Care, Diaverum, Vifor Pharma, Vircell, Fundación Renal Iñigo Álvarez de Toledo and ISCIII FEDER funds RICORS2040 (RD21/0005

Métodos y técnicas de monitoreo y predicción temprana en los escenarios de riesgos socionaturales

Esta obra concentra los métodos y las técnicas fundamentales para el seguimiento y monitoreo de las dinámicas de los escenarios de riesgos socionaturales (geológicos e hidrometeorológicos) y tiene como objetivo general orientar, apoyar y acompañar a los directivos y operativos de protección civil en aterrizar las acciones y políticas públicas enfocadas a la gestión del riesgo local de desastre