1,619 research outputs found

    Flow Equations for Non-BPS Extremal Black Holes

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    We exploit some common features of black hole and domain wall solutions of (super)gravity theories coupled to scalar fields and construct a class of stable extremal black holes that are non-BPS, but still can be described by first-order differential equations. These are driven by a "superpotential'', which replaces the central charge Z in the usual black hole potential. We provide a general procedure for finding this class and deriving the associated "superpotential''. We also identify some other cases which do not belong to this class, but show a similar behaviour.Comment: LaTeX, 21 pages, 2 figures. v2: reference added, JHEP versio

    Placenta percreta following first trimester miscarriage

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135586/1/ijgo140.pd

    Efeitos da suplementação de alto nível de cobre e de biotina na dieta de suínos de 8 a 20 kg

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    Two trials were carried out to investigate the need for supplemental biotin in the diet of weanling pigs when high dietary copper is used as growth promoter. Wheat - soybean meal based feeds, containing marginal levels of biotin (.10 ppm) were supplemented or not with .4 ppm biotin (BIO) and 250 ppm copper (COP). The diets were fed to 168 piglets weaned at 4 weeks of age with an average weight of 7.8 kg. The trials were conducted for 5 weeks. In trial 1 there was a BIO x COP interaction (P ; .05). The combination of supplemental BIO and COP did not result in further improvement in performance compared to the individual supplementation.Dois experimentos foram conduzidos para investigar a necessidade de suplementação de biotina na dieta de leitões recém desmamados quando o cobre é utilizado como promotor de crescimento. Rações com níveis marginais de biotina (0,10 ppm), formuladas à base de trigo e farelo de soja, foram suplementadas ou não com 0,4 ppm de biotina (BIO) e 250 ppm de cobre (COB) e fornecidas a 168 leitões desmamados com 4 semanas de idade e peso médio de 7,8 kg. Os experimentos tiveram duração de 5 semanas. No experimento 1 houve uma interação BIO x COB (P < 0,05) no ganho de peso dos leitões, com BIO promovendo uma melhora de 10% na ausência de COB, mas não na presença de COB; COB resultou em um aumento de 16% no ganho de peso na ausência de BIO, mas não em sua presença . Também houve uma melhora de 7% na conversão alimentar dos leitões que receberam COB (P; 0,05). A suplementação conjunta de COB e BIO não melhorou o desempenho dos animais, em relação a sua suplementação individual

    Efeitos da suplementação independente de sódio e cloro na dieta de suínos na fase inicial

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    This study was conducted to assess the effects of different dietary levels of sodium (Na) and chlorine (Cl) on performance and blood electrolyte concentration of starter pigs. The treatments consisted of diets based on corn and soybean meal containing 0.12 or 0.18% Na and 0.04; 0.12 or 0.20% Cl in a factorial arrangement. Six weaning pigs were housed in each of 12 pens in a complete randomized block design with 2 replicates per treatment. The average initial weight was 7.5 kg and the trial was conducted for 4 weeks. Sodium bicarbonate and ammonium chloride were the sources of Na and Cl, respectively. Plasma determinations of Na, Cl, Ca and P were performed at the end of the trial. Sodium did not affect performance of the piglets (P >;.10). The lower Cl level (.04% Cl) resulted in less weight gain and feed efficiency (P ; 0,10) dos animais. As dietas não suplementadas com Cl (0,04% Cl) resultaram em ganho de peso e conversão alimentar inferiores (P ; 0,10). O nível mais baixo de Cl resultou em menor concentração plasmática de Cl e P (P < 0,01), não afetando Ca e Na no plasma. As diferentes combinações de 0,12 ou 0,18% Na com 0,12 ou 0,20% Cl na dieta resultaram em desempenho adequado dos leitões

    An optimal finite element mesh for elastostatic structural analysis problems

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    This paper investigates the adaptive solution of a class of elastic structural analysis problems through re-positioning of the finite element nodal points (r-refinement) using an approach known as the moving finite element method. Initially this adaptive method is derived for the elasticity problems of interest and it is then proved that, under certain conditions, the algorithm can yield optimal piecewise linear solutions on optimal simplicial finite element meshes. The equations of linear elasticity are then used to illustrate both the method itself and the optimality result that is derived. Finally, a number of numerical calculations are made to provide verification of the theoretical results

    The Effectiveness of Maintenance Pharmacotherapies for Non-Small Cell Lung Cancer

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    Although current recommendations for the treatment of advanced non-small cell lung cancer (NSCLC) include a maximum of six cycles of platinum-based combination therapy as a first-line approach, most patients experience progression within 3–4 months. Therefore, a new treatment strategy, maintenance therapy, has been proposed, and several large randomized prospective controlled trials have shown benefits with maintenance therapy. Maintenance therapy can be classified as either continuation maintenance, which is defined as a prolongation of a part of the first-line chemotherapy or molecularly targeted agent until progression, or switch-maintenance, which is defined as the administration of a different cytotoxic chemotherapy or molecularly targeted agent immediately after induction therapy. In this article, recent results from large randomized phase III trials regarding maintenance therapy are reviewed in order to evaluate the role of maintenance therapy in NSCLC
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