157 research outputs found
Les couples homosexuels et l'enregistrement de leur union: rapprochement avec les couples hétérosexuels et recherche comparative internationale.
FDR De bescherming van fundamentele rechten in een integrerend Europa ou
Background Light in Potential Sites for the ANTARES Undersea Neutrino Telescope
The ANTARES collaboration has performed a series of {\em in situ}
measurements to study the background light for a planned undersea neutrino
telescope. Such background can be caused by K decays or by biological
activity. We report on measurements at two sites in the Mediterranean Sea at
depths of 2400~m and 2700~m, respectively. Three photomultiplier tubes were
used to measure single counting rates and coincidence rates for pairs of tubes
at various distances. The background rate is seen to consist of three
components: a constant rate due to K decays, a continuum rate that
varies on a time scale of several hours simultaneously over distances up to at
least 40~m, and random bursts a few seconds long that are only correlated in
time over distances of the order of a meter. A trigger requiring coincidences
between nearby photomultiplier tubes should reduce the trigger rate for a
neutrino telescope to a manageable level with only a small loss in efficiency.Comment: 18 pages, 8 figures, accepted for publication in Astroparticle
Physic
Landowning, Status and Population Growth
This paper considers the effects of the landowning and land reforms on economic and demographic growth by a family-optimization model with endogenous fertility and status-seeking. A land reform provides the peasant with strong incentives to limit their family size and to improve the productivity of the land. Even though the income effect due to the land reform tends to raise fertility, a strong enough status-effect outweighs it, thus generating a decrease in population growth. The European demographic history provides supporting anecdotal evidence for this theoretical result
Novel Pathway of Adipogenesis through Cross-Talk between Adipose Tissue Macrophages, Adipose Stem Cells and Adipocytes: Evidence of Cell Plasticity
INTRODUCTION: Previous studies highlight a complex relationship between lineage and phenotype for adipose tissue macrophages (ATMs), adipose stem cells (ASCs), and adipocytes, suggesting a high degree of plasticity of these cells. In the present study, using a novel co-culture system, we further characterized the interaction between ATMs, ASCs and adipocytes. RESEARCH DESIGN AND METHODS: Human adipocytes and the stromal vascular fraction containing ATMs and ASCs were isolated from human adipose tissue and co-cultured for 24 hours. FACS was used to characterize ATMs and ASCs before and after co-culture. Preadipocytes generated after co-culture were characterized by immunostaining for DLK (preadipocytes), CD14 and CD68 (ATMs), CD34 (ASCs), and Nile Red staining for lipid drops. qRT-PCR was used to quantify adipogenic markers such as C/EBPα and PPARγ. A novel fluorescent nanobead lineage tracing method was utilized before co-culture where fluorescent nanobeads were internalized by CD68 (+) ATMs. RESULTS: Co-culture of adipocytes with ATMs and ASCs increased the formation of new preadipocytes, thereby increasing lipid accumulation and C/EBPα and PPARγ gene expression. Preadipocytes originating after co-culture were positive for markers of preadipocytes, ATMs and ASCs. Moreover, fluorescent nanobeads were internalized by ATMs before co-culture and the new preadipocytes formed after co-culture also contained fluorescent nanobeads, suggesting that new preadipocytes originated in part from ATMs. The formation of CD34(+)/CD68(+)/DLK (+) cell spheres supported the interaction of ATMs, ASCs and preadipocytes. CONCLUSIONS: Cross-talk between adipocytes, ATMs and ASCs promotes preadipocyte formation. The regulation of this novel adipogenic pathway involves differentiation of ATMs to preadipocytes. The presence of CD34(+)/CD68(+)/DLK(+) cells grouped in spheres suggest that paracrine interactions between these cell types plays an important role in the generation and proliferation of new preadipocytes. This phenomenon may reflect the in vivo plasticity of adipose tissue in which ATMs play an additional role during inflammation and other disease states. Understanding this novel pathway could influence adipogenesis, leading to new treatments for obesity, inflammation, and type 2 diabetes
Sedimentation and Fouling of Optical Surfaces at the ANTARES Site
ANTARES is a project leading towards the construction and deployment of a
neutrino telescope in the deep Mediterranean Sea. The telescope will use an
array of photomultiplier tubes to detect the Cherenkov light emitted by muons
resulting from the interaction with matter of high energy neutrinos. In the
vicinity of the deployment site the ANTARES collaboration has performed a
series of in-situ measurements to study the change in light transmission
through glass surfaces during immersions of several months. The average loss of
light transmission is estimated to be only ~2% at the equator of a glass sphere
one year after deployment. It decreases with increasing zenith angle, and tends
to saturate with time. The transmission loss, therefore, is expected to remain
small for the several year lifetime of the ANTARES detector whose optical
modules are oriented downwards. The measurements were complemented by the
analysis of the ^{210}Pb activity profile in sediment cores and the study of
biofouling on glass plates. Despite a significant sedimentation rate at the
site, in the 0.02 - 0.05 cm.yr^{-1} range, the sediments adhere loosely to the
glass surfaces and can be washed off by water currents. Further, fouling by
deposits of light-absorbing particulates is only significant for surfaces
facing upwards.Comment: 18 pages, 14 figures (pdf), submitted to Astroparticle Physic
Analyzing Childlessness
Childlessness has been on the rise in many European societies. In Germany, the UK, Austria, the Netherlands, and Switzerland, childlessness has increased starting with the 1950s cohorts. In these countries, about 20 % of the women born around 1965 will remain childless. In southern Europe and the former state-socialist countries of Central and Eastern Europe, the rise in levels of childlessness is a more recent phenomenon. Yet among younger cohorts in these countries, childlessness has reached levels of 15 % or higher. In this introductory chapter, we summarize the long-term trends in childlessness and discuss the differences between European countries in the prevalence of childlessness. We also outline the structure and the logic of this volume
The ANTARES Optical Module
The ANTARES collaboration is building a deep sea neutrino telescope in the
Mediterranean Sea. This detector will cover a sensitive area of typically 0.1
km-squared and will be equipped with about 1000 optical modules. Each of these
optical modules consists of a large area photomultiplier and its associated
electronics housed in a pressure resistant glass sphere. The design of the
ANTARES optical module, which is a key element of the detector, has been
finalized following extensive R & D studies and is reviewed here in detail.Comment: 26 pages, 15 figures, to be published in NI
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