Characterization of GPS time series at the Neapolitan volcanic area by statistical analysis

The GPS time series recorded at the Neapolitan volcanic area reveals a very peculiar behavior. When a clear deformation is observed, the amplitude distribution evolves from a super‐Gaussian to a broader distribution. This behavior can be characterized by evaluating the kurtosis. Spurious periodic components were evidenced by independent component analysis and then removed by filtering the original signal. The time series for all stations was modeled with a fifth‐order polynomial fit, which represents the deformation history at that place. Indeed, when this polynomial is subtracted from the time series, the distributions again become super‐Gaussian. A simulation of the deformation time evolution was performed by superposing a Laplacian noise and a synthetic deformation history. The kurtosis of the obtained signals decreases as the superposition increases, enlightening the insurgence of the deformation. The presented approach represents a contribution aimed at adding further information to the studies about the deformation at the Neapolitan volcanic area by revealing geologically relevant data

Plasma S-adenosylmethionine, DNMT polymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore

10.1186/1471-2407-13-389BMC Cancer13-BCMA

ANALISI DELLE COMPONENTI INDIPENDETI (ICA) NELLO STUDIO DELLE DEFORMAZIONI DEL SUOLO IN AREE VULCANICHE

Independent component analysis (ICA) is a recent and well-known technique used to separate mixtures of signals. This technique has been applied to the ground deformation time-series recorded at the permanent GPS network of the Osservatorio Vesuviano-INGV in order to characterize the deformation background level in the Neapolitan volcanic area. The analysis revealed the presence of five independent periodic signals common at all the GPS stations; some of them are interpreted as effects of earth tides. The residual signal at each station represent the local ground deformation. Unfortunately the ICA cannot provide the absolute amplitude of the components, indeed we are not able to obtain a residual amplitude at each station. Then we used a stationarity analysis in order to investigate the eventual presence of local transient deformations. The ICA technique combined with the stationarity analysis has shown to be a very interesting tool for individuating ground deformation trends and could be very useful in volcanic areas monitoring

Outbreak of sars-cov-2 lineage 20i/501y.V1 in a nursing home underlines the crucial role of vaccination in both residents and staff

Elderly residents in nursing homes are at very high risk of life-threatening COVID-19-related outcomes. In this report, an epidemiological and serological investigation of a SARS-CoV-2 outbreak in an Italian nursing home is described. Among the residents, all but one (19/20) were regularly vaccinated against SARS-CoV-2. In mid-February 2021, a non-vaccinated staff member of the nursing home was diagnosed with the SARS-CoV-2 infection. Following the outbreak investigation, a total of 70% (14/20) of residents aged 77–100 years were found positive. The phylogenetic analysis showed that the outbreak was caused by the SARS-CoV-2 variant of concern 202012/01 (the so-called “UK variant”). However, all but one positive subjects (13/14) were fully asymptomatic. The only symptomatic patient was a vaccinated 86-year-old female with a highly compromised health background and deceased approximately two weeks later. The subsequent serological investigation showed that the deceased patient was the only vaccinated subject that did not develop the anti-spike protein antibody response, therefore being likely a vaccine non-responder. Although the available mRNA SARS-CoV-2 vaccine was not able to prevent several asymptomatic infections, it was able to avert most symptomatic disease cases caused by the SARS-CoV-2 variant of concern 202012/01 in nursing home residents

Generalized Arcsine Law and Stable Law in an Infinite Measure Dynamical System

Limit theorems for the time average of some observation functions in an infinite measure dynamical system are studied. It is known that intermittent phenomena, such as the Rayleigh-Benard convection and Belousov-Zhabotinsky reaction, are described by infinite measure dynamical systems.We show that the time average of the observation function which is not the $L^1(m)$ function, whose average with respect to the invariant measure $m$ is finite, converges to the generalized arcsine distribution. This result leads to the novel view that the correlation function is intrinsically random and does not decay. Moreover, it is also numerically shown that the time average of the observation function converges to the stable distribution when the observation function has the infinite mean.Comment: 8 pages, 8 figure

Fascitis necrotizante, cuando el tiempo vale oro

La Fascitis Necrotizante es una infección de partes blandas que puede provocar una rápida destrucción del tejido afectado con necrosis y sepsis grave, potencialmente mortal. Los factores predisponentes son diabetes, neoplasias, alcoholismo, enfermedad hepática y renal crónica, entre otras. Es una urgencia médica que requiere un tratamiento quirúrgico precoz, y terapia antibiótica endovenosa de amplio espectro con el fin de disminuir la tasa de mortalidad. Presentamos el caso de un paciente con antecedente de linfoma T hepático que presentó fascitis necrotizante en el miembro inferior izquierdo secundario a Bacillus Cereus

positive predictive value for malignancy on surgical excision of breast lesions of uncertain malignant potential b3 diagnosed by stereotactic vacuum assisted needle core biopsy vancb a large multi institutional study in italy

Abstract Percutaneous core biopsy (CB) has been introduced to increase the ability of accurately diagnosing breast malignancies without the need of resorting to surgery. Compared to conventional automated 14 gauge needle core biopsy (NCB), vacuum-assisted needle core biopsy (VANCB) allows obtaining larger specimens and has recognized advantages particularly when the radiological pattern is represented by microcalcifications. Regardless of technical improvements, a small percentage of percutaneous CBs performed to detect breast lesions are still classified, according to European and UK guidelines, in the borderline B3 category, including a group of heterogeneous lesions with uncertain malignant potential. We aimed to assess the prevalence and positive predictive values (PPV) on surgical excision (SE) of B3 category (overall and by sub-categories) in a large series of non-palpable breast lesions assessed through VANCB, also comparison with published data on CB. Overall, 26,165 consecutive stereotactic VANCB were identified in 22 Italian centres: 3107 (11.9%) were classified as B3, of which 1644 (54.2%) proceeded to SE to establish a definitive histological diagnosis of breast pathology. Due to a high proportion of microcalcifications as main radiological pattern, the overall PPV was 21.2% (range 10.6%–27.3% for different B3 subtypes), somewhat lower than the average value (24.5%) from published studies (range 9.9%–35.1%). Our study, to date the largest series of B3 with definitive histological assessment on SE, suggests that B3 lesions should be referred for SE even if VANCB is more accurate than NCB in the diagnostic process of non-palpable, sonographically invisible breast lesions