345 research outputs found

    Deep-water macroalgae from the Canary Islands: new records and biogeographical relationships

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    Due to the geographical location and paleobiogeography of the Canary Islands, the seaweed flora contains macroalgae with different distributional patterns. In this contribution, the biogeographical relations of several new records of deep-water macroalgae recently collected around the Canarian archipelago are discussed. These are Bryopsidella neglecta (Berthotd) Rietema,Discosporangium mesarthrocarpum (Meneghini) Hauck, Hincksia onslowensis (Amsler et Kapraun)P.C. Silva, Syringoderma floridana Henry, Peyssonnelia harveyana J. Agardh, Cryptonemia seminervis(C. Agardh) J. Agardh, Botryodadia wynnei Ballantine, Gloiocladia blomquistii (Searles) R. E.Norris, PIahchrysis peltata (W. R. Taylor) P. Huv4 et H. Huv4, Leptofauchea brasiliensis Joly, and Sarcodiotheca divaricata W. R. Taylor. These new records, especially those in the Florideophyceae,support the strong affinity of the Canary Islands seaweed flora with the warm-temperate Mediterranean-Atlantic region. Some species are recorded for the first time from the east coast of the Atlantic Ocean, enhancing the biogeographic relations of the Canarian marine flora with that of the western Atlantic regions

    Social Pain and the Brain: Controversies, Questions, and Where to Go from Here

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    Emerging evidence has shown that social pain--the painful feelings that follow from social rejection, exclusion, or loss--relies on some of the same neural regions that process physical pain, highlighting a possible physical-social pain overlap. However, the hypothesis that physical pain and social pain rely on shared neural systems has been contested. This review begins by summarizing research supporting the physical-social pain overlap. Next, three criticisms of this overlap model are presented and addressed by synthesizing available research. These criticisms include the suggestions that (a) neural responses to social pain are indicative of conflict detection processes, rather than distress; (b) all negative affective processes, rather than social pain specifically, activate these pain-related neural regions; and (c) neural responses to social (and physical) pain reflect the processing of salience, rather than hurt. Implications of these findings for understanding social and physical pain are discussed, and key next steps are suggested

    Eco-engineered rock pools: a concrete solution to biodiversity loss and urban sprawl in the marine environment

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    journal_title: Environmental Research Letters article_type: lett article_title: Eco-engineered rock pools: a concrete solution to biodiversity loss and urban sprawl in the marine environment copyright_information: © 2016 IOP Publishing Ltd license_information: cc-by Original content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. date_received: 2016-05-12 date_accepted: 2016-08-10 date_epub: 2016-09-1

    “Working the System”—British American Tobacco's Influence on the European Union Treaty and Its Implications for Policy: An Analysis of Internal Tobacco Industry Documents

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    Katherine Smith and colleagues investigate the ways in which British American Tobacco influenced the European Union Treaty so that new EU policies advance the interests of major corporations, including those that produce products damaging to health

    Structural Basis for GTP-Dependent Dimerization of Hydrogenase Maturation Factor HypB

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    Maturation of [NiFe]-hydrogenase requires the insertion of iron, cyanide and carbon monoxide, followed by nickel, to the catalytic core of the enzyme. Hydrogenase maturation factor HypB is a metal-binding GTPase that is essential for the nickel delivery to the hydrogenase. Here we report the crystal structure of Archeoglobus fulgidus HypB (AfHypB) in apo-form. We showed that AfHypB recognizes guanine nucleotide using Asp-194 on the G5 loop despite having a non-canonical NKxA G4-motif. Structural comparison with the GTPγS-bound Methanocaldococcus jannaschii HypB identifies conformational changes in the switch I region, which bring an invariant Asp-72 to form an intermolecular salt-bridge with another invariant residue Lys-148 upon GTP binding. Substitution of K148A abolished GTP-dependent dimerization of AfHypB, but had no significant effect on the guanine nucleotide binding and on the intrinsic GTPase activity. In vivo complementation study in Escherichia coli showed that the invariant lysine residue is required for in vivo maturation of hydrogenase. Taken together, our results suggest that GTP-dependent dimerization of HypB is essential for hydrogenase maturation. It is likely that a nickel ion is loaded to an extra metal binding site at the dimeric interface of GTP-bound HypB and transferred to the hydrogenase upon GTP hydrolysis

    The Chemistry of Griseofulvin

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