708 research outputs found

    Inverse modeling of soil water content to estimate the hydraulic properties of a shallow soil and the associated weathered bedrock

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    International audienceSummary Modeling soil water flow requires the knowledge of numerous parameters associated to the water content and the soil hydraulic properties. Direct estimations of those parameters in laboratory require expensive equipment and the obtained parameters are generally not representative at the field scale because of the limitation of core sample size. Indirect methods such as inverse modeling are known to get efficient estimations and are easier to set up and process for large-scale studies. In this study, we investigated the capacity of an inverse modeling procedure to estimate the soil and the bedrock hydrodynamic properties only from in situ soil water content measurements at multiple depths under natural conditions. Multi-objective parameter optimization was performed using the HYDRUS-1D software and an external optimization procedure based on the NSGA-II algorithm. In a midslope shallow soil, water content was monitored at 3 depths, 20, 40, and 60cm during 12 intense rainfall events, whose amounts ranged between 50 and 250mm and duration between 1 and 5days. The vertical profile was considered as 2 layers of soils above a third layer representing the weathered schist rock. This deep layer acted as a deep boundary condition, which features the bedrock permeability and water storage. Each layer was described trough the 6 parameters of the Mualem\textendashvan Genuchten formulation. The calibrated parameters appeared to have very low uncertainty while allowing a good modelisation of the observed water content variations. The calibrated saturated water content was close to the laboratory porosity measurements while the saturated hydraulic conductivity showed that the soil was highly permeable, as measured in the field. The inverse modeling approach allowed an estimation of the hydraulic properties of the bedrock layer where no measurement was available. The bedrock layer was found to have a low saturated hydraulic conductivity (\textless5mmh-1), which means that the schist bedrock is poorly weathered and that saturated area can be generated above this depth, as it was observed. The simulated water contents were generally close to the measured water contents, but the model failed sometimes to reproduce the saturation of the soil in the deeper layers, probably because of sub-surface flux at the soil/bedrock interface. In these cases, further investigation will have to be made by using a 2D-model

    Blood histamine levels (BHL) in infants and children with respiratory and non-respiratory diseases.

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    BACKGROUND: Blood histamine levels are decreased after severe allergic reactions and in various chronic diseases. AIMS: To study blood histamine levels in infants and children with acute infectious and non-infectious, non-allergic, disease. METHODS: Blood histamine levels were investigated by a fluorometric method in infants and children admitted to hospital with bronchiolitis, non-wheezing bronchitis, acute infections of the urinary tract, skin and ear-nose-throat, gastroenteritis, or hyperthermia of unknown aetiology. Results of blood histamine levels and white blood cell counts were compared with those obtained for children recovering from benign non-infectious, non-allergic illnesses. RESULTS: As compared with control children, white blood cell numbers were significantly increased in children with acute infections of the urinary tract, skin and ear-nose-throat, and were significantly decreased in children with gastroenteritis. Blood histamine levels were significantly lower in children with gastroenteritis and hyperthermia than in children with other diseases and control children. It was not possible to correlate blood histamine levels and the number of blood basophils. CONCLUSIONS: BHL are significantly decreased in infants and children with acute gastroenteritis and hyperthermia of unknown aetiology. The mechanisms responsible for the decrease in blood histamine levels in children with gastroenteritis and hyperthermia are discussed

    Controlling the Frequency-Temperature Sensitivity of a Cryogenic Sapphire Maser Frequency Standard by Manipulating Fe3+ Spins in the Sapphire Lattice

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    To create a stable signal from a cryogenic sapphire maser frequency standard, the frequency-temperature dependence of the supporting Whispering Gallery mode must be annulled. We report the ability to control this dependence by manipulating the paramagnetic susceptibility of Fe3+ ions in the sapphire lattice. We show that the maser signal depends on other Whispering Gallery modes tuned to the pump signal near 31 GHz, and the annulment point can be controlled to exist between 5 to 10 K depending on the Fe3+ ion concentration and the frequency of the pump. This level of control has not been achieved previously, and will allow improvements in the stability of such devices.Comment: 17 pages, 10 figure

    Ultra-Low Noise Microwave Extraction from Fiber-Based Optical Frequency Comb

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    In this letter, we report on all-optical fiber approach to the generation of ultra-low noise microwave signals. We make use of two erbium fiber mode-locked lasers phase locked to a common ultra-stable laser source to generate an 11.55 GHz signal with an unprecedented relative phase noise of -111 dBc/Hz at 1 Hz from the carrier.The residual frequency instability of the microwave signals derived from the two optical frequency combs is below 2.3 10^(-16) at 1s and about 4 10^(-19) at 6.5 10^(4)s (in 5 Hz bandwidth, three days continuous operation).Comment: 12 pages, 3 figure

    ITERATED QUASI-REVERSIBILITY METHOD APPLIED TO ELLIPTIC AND PARABOLIC DATA COMPLETION PROBLEMS

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    International audienceWe study the iterated quasi-reversibility method to regularize ill-posed elliptic and parabolic problems: data completion problems for Poisson's and heat equations. We define an abstract setting to treat both equations at once. We demonstrate the convergence of the regularized solution to the exact one, and propose a strategy to deal with noise on the data. We present numerical experiments for both problems: a two-dimensional corrosion detection problem and the one-dimensional heat equation with lateral data. In both cases, the method prove to be efficient even with highly corrupted data

    Genes but Not Genomes Reveal Bacterial Domestication of Lactococcus Lactis

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    BACKGROUND: The population structure and diversity of Lactococcus lactis subsp. lactis, a major industrial bacterium involved in milk fermentation, was determined at both gene and genome level. Seventy-six lactococcal isolates of various origins were studied by different genotyping methods and thirty-six strains displaying unique macrorestriction fingerprints were analyzed by a new multilocus sequence typing (MLST) scheme. This gene-based analysis was compared to genomic characteristics determined by pulsed-field gel electrophoresis (PFGE). METHODOLOGY/PRINCIPAL FINDINGS: The MLST analysis revealed that L. lactis subsp. lactis is essentially clonal with infrequent intra- and intergenic recombination; also, despite its taxonomical classification as a subspecies, it displays a genetic diversity as substantial as that within several other bacterial species. Genome-based analysis revealed a genome size variability of 20%, a value typical of bacteria inhabiting different ecological niches, and that suggests a large pan-genome for this subspecies. However, the genomic characteristics (macrorestriction pattern, genome or chromosome size, plasmid content) did not correlate to the MLST-based phylogeny, with strains from the same sequence type (ST) differing by up to 230 kb in genome size. CONCLUSION/SIGNIFICANCE: The gene-based phylogeny was not fully consistent with the traditional classification into dairy and non-dairy strains but supported a new classification based on ecological separation between "environmental" strains, the main contributors to the genetic diversity within the subspecies, and "domesticated" strains, subject to recent genetic bottlenecks. Comparison between gene- and genome-based analyses revealed little relationship between core and dispensable genome phylogenies, indicating that clonal diversification and phenotypic variability of the "domesticated" strains essentially arose through substantial genomic flux within the dispensable genome

    Bronchoalveolar lavage in infants with recurrent lower respiratory symptoms

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    Background: Few data are available about the inflammatory cytokine profile of bronchoalveolar lavage (BAL) from young children with frequent wheeze. The first aim was to investigate the BAL cellular and cytokine profiles in infants with recurrent lower respiratory symptoms in whom bronchoscopy was indicated for clinical symptom evaluation. The second aim was to relate the BAL results with the histological findings of the endobronchial carina biopsies. Methods: Thirty-nine infants (median age 0.9 years) underwent lung function testing by whole-body plethysmography prior to the bronchoscopy. The BAL differential cell counts and cytokine levels were quantified. These findings were compared with the histological findings of the endobronchial carina biopsies. Results: The differential cytology reflected mainly that described for healthy infants with lymphocyte counts at the upper range level. A positive association between BAL CD8+ lymphocytes and neutrophils and endobronchial reticular basement membrane was found. Detectable levels of pro-inflammatory cytokine proteins IL-1 beta, IL-17A, IL-18, IL-23, and IL-33 were found, whereas levels of Th2-type cytokine proteins were low. Frequent wheeze was the only clinical characteristic significantly related to detectable combined pro-inflammatory cytokine profile. Lung function did not correlate with any cytokine. Conclusions: A positive association between BAL CD8+ lymphocytes and neutrophils and endobronchial reticular basement thickness was found. Detectable production of pro-inflammatory cytokines associated positively with frequent wheeze.Peer reviewe

    Singular regional brightening events on Titan as seen by Cassini/VIMS

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    Titan, the largest satellite of Saturn, is the only satellite in the solar system with a dense atmosphere. The close and continuous observations of Titan by the Cassini spacecraft, in orbit around Saturn since July 2004, bring us evidences that Titan tropo-sphere and low stratosphere experience an exotic, but complete meteorological cycle similar to the Earth hy-drological cycle, with hydrocarbons evaporation, con-densation in clouds, and rainfall. Cassini monitoring campaigns also demonstrate that Titan’s cloud cover-age and climate vary with latitude. Titan’s tropics, with globally weak meteorological activity and widespread dune fields, seem to be slightly more arid than the poles, where extensive and numerous liquid reservoirs and sustained cloud activity were discovered. Only a few tropospheric clouds have been observed at Titan’s tropics during the southern summer [2-4]. As equinox was approaching (in August 2009), they oc-curred more frequently and appeared to grow in strength and size [5-7]
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