224 research outputs found
Managing global expansion of media products and brands: A case study of FHM
By focusing on the case study of For Him Magazine (FHM)—a magazine that currently sells in 30 editions across 5 continents—this article explores the economics and main managerial challenges associated with global expansion of media products. The success of FHM demonstrates that, to calculate the full returns available from the brand image created by a magazine title, publishers will take into account not only opportunities for domestic and international exploitation of the magazine, but also the potential to extend the brand across additional media platforms and additional complementary product markets. This study focuses on how global expansion of FHM has been managed
In vitro formation of Ca-oxalates and the mineral glushinskite by fungal interaction with carbonate substrates and seawater
This study investigates the in vitro formation of Ca-oxalates and glushinskite through fungal interaction with carbonate substrates and seawater as a process of biologically induced metal recycling and neo-mineral formation. The study also emphasizes the role of the substrates as metal donors. In the first experiment, thin sections prepared from dolomitic rock samples of Terwagne Formation (Carboniferous, Viséan, northern France) served as substrates. The thin sections placed in Petri dishes were exposed to fungi grown from naturally existing airborne spores. In the second experiment, fungal growth and mineral formation was monitored using only standard seawater (SSW) as a substrate. Fungal growth media consisted of a high protein/carbohydrates and sugar diet with demineralized water for irrigation. Fungal growth process reached completion under uncontrolled laboratory conditions. The newly formed minerals and textural changes caused by fungal attack on the carbonate substrates were investigated using light and scanning electron microscopy (SEM-EDX), x-ray diffraction (XRD) and Raman spectroscopy. The fungal interaction and attack on the dolomitic and seawater substrates resulted in the formation of Ca-oxalates (weddellite CaC2O4·2(H2O), whewellite (CaC2O4·(H2O)) and glushinskite MgC2O4·2(H2O) associated with the destruction of the original hard substrates and their replacement by the new minerals. Both of Ca and Mg were mobilized from the experimental substrates by fungi. This metal mobilization involved a recycling of substrate metals into newly formed minerals. The biochemical and diagenetic results of the interaction strongly marked the attacked substrates with a biological fingerprint. Such fingerprints are biomarkers of primitive life. The formation of glushinskite is of specific importance that is related, besides its importance as a biomineral bearing a recycled Mg, to the possibility of its transformation through diagenetic pathway into an Mg carbonate. This work is the first report on the in vitro formation of the mineral glushinskite through fungal interaction with carbonate and seawater substrates. Besides recording the detailed Raman signature of various crystal habits of Mg- and Ca-oxalates, the Raman spectroscopy proved two new crystal habits for glushinskite. The results of this work document the role of microorganisms as metal recyclers in biomineralization, neo-mineral formation, sediment diagenesis, bioweathering and in the production of mineral and diagenetic biomarkers. They also reveal the capacity of living fungi to interact with liquid substrates and precipitate new minerals
Framing the barriers to construction industry transformation
Purpose (limit 100 words) ‘Transforming construction’ is a wide-ranging strategic term, under which sit numerous initiatives. It is the latest, in a long line of strategies and reports introduced to with the intention of industry improvement. Arguably, many of these fail to achieve their aim. The barriers preventing the adoption of transforming construction initiatives are therefore limiting the potential benefits of the strategy. The aim of this research is to formally identify and understand how these barriers are framed and how these frames can be changed so that the barriers can be overcome, and the wider strategy benefits realised. Design/methodology/approach (limit 100 words) A literature review is undertaken to identify ‘transforming construction’ initiatives. Fifteen semi-structured interviews are then undertaken with construction professionals and analysed via narrative analysis to identify and understand perceived barriers to these initiatives. Framing is utilised as a theoretical lens to categorise these barriers and understand how ‘shifts’ in the frames held can be achieved and the barriers overcome. Findings (limit 100 words) Barriers to transforming construction initiatives are identified as wicked problems. This allows a new perspective on such initiatives to be gained. The results also reveal how construction professionals frame such barriers, viewing themselves as bystanders with initiatives and practices ‘bigger’ than themselves and their roles. How these frames can be ‘shifted’ from bystander to active participant is identified. Such a shift can serve as a blueprint for industry professionals so that the initiatives identified can be successfully implemented thereby increasing the success of the transforming construction strategy. Originality/value (limit 100 words) This paper addresses a gap in current research around the perceptions held by construction professionals of the initiatives that sit under the transforming construction strategy. Addressing this gap allows the diagnosis of barriers that have previously served to prevent initiatives gaining traction. The findings contribute to both the existing literature and current industry practice by highlighting how the barriers are framed, and how such frames can be ‘shifted’ to support the realisation of long promised strategy benefits
Scrub typhus ecology: a systematic review of Orientia in vectors and hosts
Abstract
Scrub typhus, caused by Orientia tsutsugamushi, is an important and neglected vector-borne zoonotic disease with an expanding known distribution. The ecology of the disease is complex and poorly understood, impairing discussion of public health interventions. To highlight what we know and the themes of our ignorance, we conducted a systematic review of all studies investigating the pathogen in vectors and non-human hosts. A total of 276 articles in 7 languages were included, with 793 study sites across 30 countries. There was no time restriction for article inclusion, with the oldest published in 1924. Seventy-six potential vector species and 234 vertebrate host species were tested, accounting for over one million trombiculid mites (‘chiggers’) and 83,000 vertebrates. The proportion of O. tsutsugamushi positivity was recorded for different categories of laboratory test and host species. Vector and host collection sites were geocoded and mapped. Ecological data associated with these sites were summarised. A further 145 articles encompassing general themes of scrub typhus ecology were reviewed. These topics range from the life-cycle to transmission, habitats, seasonality and human risks. Important gaps in our understanding are highlighted together with possible tools to begin to unravel these. Many of the data reported are highly variable and inconsistent and minimum data reporting standards are proposed. With more recent reports of human Orientia sp. infection in the Middle East and South America and enormous advances in research technology over recent decades, this comprehensive review provides a detailed summary of work investigating this pathogen in vectors and non-human hosts and updates current understanding of the complex ecology of scrub typhus. A better understanding of scrub typhus ecology has important relevance to ongoing research into improving diagnostics, developing vaccines and identifying useful public health interventions to reduce the burden of the disease.</jats:p
Adaptive isogeometric analysis for phase‐field modeling of anisotropic brittle fracture
The surface energy a phase‐field approach to brittle fracture in anisotropic materials is also anisotropic and gives rise to second‐order gradients in the phase field entering the energy functional. This necessitates C 1 continuity of the basis functions which are used to interpolate the phase field. The basis functions which are employed in isogeometric analysis (IGA), such as nonuniform rational B‐splines and T‐splines naturally possess a higher order continuity and are therefore ideally suited for phase‐field models which are equipped with an anisotropic surface energy. Moreover, the high accuracy of spline discretizations, also relative to their computational demand, significantly reduces the fineness of the required discretization. This holds a fortiori if adaptivity is included. Herein, we present two adaptive refinement schemes in IGA, namely, adaptive local refinement and adaptive hierarchical refinement, for phase‐field simulations of anisotropic brittle fracture. The refinement is carried out using a subdivision operator and exploits the Bézier extraction operator. Illustrative examples are included, which show that the method can simulate highly complex crack patterns such as zigzag crack propagation. An excellent agreement is obtained between the solutions from global refinement and adaptive refinement, with a reasonable reduction of the computational effort when using adaptivity
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI 2 SD above the median). Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining https://researchonline.ljmu.ac.uk/images/research_banner_face_lab_290.jpgunderweight or thinness. Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesity
Factors affecting bedside handover reporting by nurses at a tertiary hospital in Kenya
Objectives: This study aimed at finding out a) nurses' knowledge of bedside handover report, b) attitudes of nurses towards bedside handover report, and c) perceived barriers towards bedside handover report at KCTRH (Kapsabet County Teaching and Referral Hospital).
Methodology: A descriptive cross-sectional design was used among 44 nurses working in the in-patient department at KCTRH. A self-administered structured questionnaire was used to collect data among eligible participants.
Participants: The target population constituted nurses working at the KCTRH in-patient departments. There were a total number of around 50 in-patient nurses.
Results: A total of (n=42) nurses participated in the study. A significant number (n=42) recognized that a handover report is essential in providing nursing care, (n=33) noted that a handover report should contain information of the client's history and presenting diagnosis. On the other hand, (n=19) noted that a breach of client privacy would hinder its implementation.
Conclusion: Nurses recognize the critical role of bedside handover in the quest for achieving quality care at the bedside. There is also much willingness among the nurses to participate in the implementation of the bedside handover report at KCTRH
Gap acceptance and Driver behavior at intersections in Minna, North Central Nigeria
The headways, spacing distributions and gap acceptance were measured from two main intersections in Minna, Central Nigeria/The average critical gap and spacing for stadium junction are 2.39 seconds and 11.08m respectively, and that of Mustapha hospital junction are 2.28 seconds and 9.56m respectively. The gap size at the intersections ranges between 1 and 57 seconds. Drivers accept gaps ranging from 2.89 to 3.72 seconds with an average of 3.2 seconds at Mustapha hospital junction and the average time of movement is 2.06 seconds. Similarly, drivers accept gaps ranging from 3.60 seconds and 4.5 seconds with an average of 4.05 seconds at Stadium Junction, and the average time of movement is 2.69 seconds. Comparing these values with the respective critical gaps from the Highway Capacity Manual shows that only values from stadium junction get close. This shows that the delays at the intersections are due mostly to driver impatience and intolerance which at times lead to accidents at the intersections. Hence, it can be concluded that traffic accidents at the intersections are due mostly to driver judgment rather than gap availability
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