919 research outputs found

    MRI and clinical resolution of a suspected intracranial toxoplasma granuloma with medical treatment in a domestic short hair cat

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    A two-year-old cat was presented with a left paradoxical vestibular syndrome. MRI of the brain revealed an extra-axial homogenously contrast enhancing mass in the region of the left caudal cerebellar peduncle. Toxoplasma serology was consistent with active infection and the lesion was suspected to be a toxoplasma granuloma. Following eight weeks of tapering oral prednisolone and 11 weeks of oral clindamycin treatment, repeat MRI revealed resolution of the lesion. Eighteen months after initial diagnosis, the cat remained neurologically normal. Differential diagnoses for a solitary, extra-axial, contrast enhancing mass lesion in the feline brain should include toxoplasma granuloma, which can undergo MRI and clinical resolution with medical treatment

    Self-rated health among Greenlandic Inuit and Norwegian Sami adolescents: associated risk and protective correlates

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    Objectives. Self-rated health (SRH) and associated risk and protective correlates were investigated among two indigenous adolescent populations, Greenlandic Inuit and Norwegian Sami. Design. Cross-sectional data were collected from ‘‘Well-being among Youth in Greenland’’ (WBYG) and ‘‘The Norwegian Arctic Adolescent Health Study’’ (NAAHS), conducted during 2003 2005 and comprising 10th and 11th graders, 378 Inuit and 350 Sami. Methods. SRH was assessed by one single item, using a 4-point and 5-point scale for NAAHS and WBYG, respectively. Logistic regressions were performed separately for each indigenous group using a dichotomous measure with ‘‘very good’’ (NAAHS) and ‘‘very good/good’’ (WBYG) as reference categories. We simultaneously controlled for various socio-demographics, risk correlates (drinking, smoking, violence and suicidal behaviour) and protective correlates (physical activity, well-being in school, number of close friends and adolescent parent relationship). Results. A majority of both Inuit (62%) and Sami (89%) youth reported ‘‘good’’ or ‘‘very good’’ SRH. The proportion of ‘‘poor/fair/not so good’’ SRH was three times higher among Inuit than Sami (38% vs. 11%, p50.001). Significantly more Inuit females than males reported ‘‘poor/fair’’SRH(44% vs. 29%, p50.05),while no gender differences occurred among Sami (12% vs. 9%, p50.08). In both indigenous groups, suicidal thoughts (risk) and physical activity (protective) were associated with poor and good SRH, respectively. Conclusions. In accordance with other studies of indigenous adolescents, suicidal thoughts were strongly associated with poorer SRH among Sami and Inuit. The Inuit Sami differences in SRH could partly be due to higher ‘‘risk’’ and lower ‘‘protective’’ correlates among Inuit than Sami. The positive impact of physical activity on SRH needs to be targeted in future intervention programs

    Mass balance of the Greenland ice sheet (2003-2008) from ICESat data:The impact of interpolation, sampling and firn density

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    ICESat has provided surface elevation measurements of the ice sheets since the launch in January 2003, resulting in a unique dataset for monitoring the changes of the cryosphere. Here, we present a novel method for determining the mass balance of the Greenland ice sheet, derived from ICESat altimetry data. <br><br> Three different methods for deriving elevation changes from the ICESat altimetry dataset are used. This multi-method approach provides a method to assess the complexity of deriving elevation changes from this dataset. <br><br> The altimetry alone can not provide an estimate of the mass balance of the Greenland ice sheet. Firn dynamics and surface densities are important factors that contribute to the mass change derived from remote-sensing altimetry. The volume change derived from ICESat data is corrected for changes in firn compaction over the observation period, vertical bedrock movement and an intercampaign elevation bias in the ICESat data. Subsequently, the corrected volume change is converted into mass change by the application of a simple surface density model, in which some of the ice dynamics are accounted for. The firn compaction and density models are driven by the HIRHAM5 regional climate model, forced by the ERA-Interim re-analysis product, at the lateral boundaries. <br><br> We find annual mass loss estimates of the Greenland ice sheet in the range of 191 ± 23 Gt yr<sup>−1</sup> to 240 ± 28 Gt yr<sup>−1</sup> for the period October 2003 to March 2008. These results are in good agreement with several other studies of the Greenland ice sheet mass balance, based on different remote-sensing techniques
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