1,106 research outputs found
Transverse crack modelling and validation in rotor systems including thermal effects
In this paper a model is described that allows to simulate the static behaviour of a transversal crack in a horizontal rotor, under the action of the weight and other possible static loads and the dynamical behaviour of the rotating cracked shaft. The crack “breaths”, i.e. the mechanism of opening and closing of the crack is ruled by the stress acting on the cracked section due to the external loads; in a rotor the stress are time depending with a period equal to the period of rotation, thus the crack “periodically breaths”. An original simplified model is described that allows cracks of different shape to be modelled and thermal stresses to be taken into account, since they may influence the opening and closing mechanism. The proposed method has been validated using two criteria. At first the crack “breathing” mechanism, simulated with the model has been compared with the results obtained by a non-linear 3D FEM calculation and a good agreement in the results has been observed. Then, the proposed model allows the development of the equivalent cracked beam. The results of this model are compared with those obtained by the above said 3D FEM. Also in this case, there is a good agreement in the results. 
Therefore the proposed crack model and equivalent beam model can be inserted in the finite beam element model used for the rotor dynamical behavior simulation: the obtained equations have time depending coefficients, but they can be integrated in the frequency domain by using the harmonic balance method. The model is suitable for finite beam elements with 6 degrees of freedom per node, in order to account also for torsion vibrations and coupling between torsion and flexural vibrations
Leaf Eh and pH: A Novel Indicator of Plant Stress. Spatial, Temporal and Genotypic Variability in Rice (Oryza sativa L.)
A wealth of knowledge has been published in the last decade on redox regulations in plants. However, these works remained largely at cellular and organelle levels. Simple indicators of oxidative stress at the plant level are still missing. We developed a method for direct measurement of leaf Eh and pH, which revealed spatial, temporal, and genotypic variations in rice. Eh (redox potential) and Eh@pH7 (redox potential corrected to pH 7) of the last fully expanded leaf decreased after sunrise. Leaf Eh was high in the youngest leaf and in the oldest leaves, and minimum for the last fully expanded leaf. Leaf pH decreased from youngest to oldest leaves. The same gradients in Eh-pH were measured for various varieties, hydric conditions, and cropping seasons. Rice varieties differed in Eh, pH, and/or Eh@pH7. Leaf Eh increases and leaf pH decreases with plant age. These patterns and dynamics in leaf Eh-pH are in accordance with the pattern and dynamics of disease infections. Leaf Eh-pH can bring new insight on redox processes at plant level and is proposed as a novel indicator of plant stress/health. It could be used by agronomists, breeders, and pathologists to accelerate the development of crop cultivation methods leading to agroecological crop protection
High-contrast 10-fs OPCPA-based Front-End for the Apollon-10PW laser (Orale)
International audienceWe present a high-contrast 10-fs Front-End for Ti:sapphire PW-lasers within the Apollon-10PW project. This injector uses OPCPA pumped at 100 Hz by Yb-based CPA chain. Combination of OPCPA and XPW permits a >10 12 contrast ratio
Modeling target bulk heating resulting from ultra-intense short pulse laser irradiation of solid density targets
Isochoric heating of solid-density matter up to a few tens of eV is of interest for investigating astrophysical or inertial fusion scenarios. Such ultra-fast heating can be achieved via the energy deposition of short-pulse laser generated electrons. Here, we report on experimental measurements of this process by means of time-and space-resolved optical interferometry. Our results are found in reasonable agreement with a simple numerical model of fast electron-induced heating. (C) 2013 AIP Publishing LLC.</p
Synthesis and characterization of core-shell structure silica-coated Fe29.5Ni70.5 nanoparticles
In view of potential applications of magnetic particles in biomedicine and
electromagnetic devices, we made use of the classical Stober method
base-catalysed hydrolysis and condensation of tetraethoxysilane (TEOS) to
encapsulate FeNi nanoparticles within a silica shell. An original stirring
system under high power ultrasounds made possible to disperse the otherwise
agglomerated particles. Sonication guaranteed particles to remain dispersed
during the Stober synthesis and also improved the efficiency of the method. The
coated particles are characterized by electron microscopy (TEM) and
spectroscopy (EDX) showing a core-shell structure with a uniform layer of
silica. Silica-coating does not affect the core magnetic properties. Indeed,
all samples are ferromagnetic at 77 K and room temperature and the Curie point
remains unchanged. Only the coercive force shows an unexpected non-monotonous
dependence on silica layer thickness.Comment: Regular paper submited to international peer-reveiwed journa
Clinical selection strategies to identify ischemic stroke patients with large anterior vessel occlusion: results from SITS-ISTR (Safe Implementation of Thrombolysis in Stroke International Stroke Thrombolysis Registry)
Background and Purpose—The National Institutes of Health Stroke Scale (NIHSS) correlates with presence of large anterior vessel occlusion (LAVO). However, the application of the full NIHSS in the prehospital setting to select patients eligible for treatment with thrombectomy is limited. Therefore, we aimed to evaluate the prognostic value of simple clinical selection strategies.
Methods—Data from the Safe Implementation of Thrombolysis in Stroke International Stroke Thrombolysis Registry (January 2012–May 2014) were analyzed retrospectively. Patients with complete breakdown of NIHSS scores and documented vessel status were included. We assessed the association of prehospital stroke scales and NIHSS symptom profiles with LAVO (internal carotid artery, carotid-terminus or M1-segment of the middle cerebral artery).
Results—Among 3505 patients, 23.6% (n=827) had LAVO. Pathological finding on the NIHSS item best gaze was strongly associated with LAVO (adjusted odds ratio 4.5, 95% confidence interval 3.8–5.3). All 3 face–arm–speech–time test (FAST) items identified LAVO with high sensitivity. Addition of the item gaze to the original FAST score (G-FAST) or high scores on other simplified stroke scales increased specificity. The NIHSS symptom profiles representing total anterior syndromes showed a 10-fold increased likelihood for LAVO compared with a nonspecific clinical profile. If compared with an NIHSS threshold of ≥6, the prehospital stroke scales performed similarly or even better without losing sensitivity.
Conclusions—Simple modification of the face–arm–speech–time score or evaluating the NIHSS symptom profile may help to stratify patients’ risk of LAVO and to identify individuals who deserve rapid transfer to comprehensive stroke centers. Prospective validation in the prehospital setting is required
Focusing Dynamics of High-Energy Density, Laser-Driven Ion Beams
The dynamics of the focusing of laser-driven ion beams produced from concave solid targets was studied. Most of the ion beam energy is observed to converge at the center of the cylindrical targets with a spot diameter of 30 mu m, which can be very beneficial for applications requiring high beam energy densities. Also, unbalanced laser irradiation does not compromise the focusability of the beam. However, significant filamentation occurs during the focusing, potentially limiting the localization of the energy deposition region by these beams at focus. These effects could impact the applicability of such high-energy density beams for applications, e. g., in proton-driven fast ignition
Tracking tracer motion in a 4-D electrical resistivity tomography experiment
A new framework for automatically tracking subsurface tracers in electrical resistivity tomography (ERT) monitoring images is presented. Using computer vision and Bayesian inference techniques, in the form of a Kalman filter, the trajectory of a subsurface tracer is monitored by predicting and updating a state model representing its movements. Observations for the Kalman filter are gathered using the maximally stable volumes algorithm, which is used to dynamically threshold local regions of an ERT image sequence to detect the tracer at each time step. The application of the framework to the results of 2-D and 3-D tracer monitoring experiments show that the proposed method is effective for detecting and tracking tracer plumes in ERT images in the presence of noise, without intermediate manual intervention
Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth
Co-infections alter the host immune response but how the systemic and local processes at the site of infection interact is still unclear. The majority of studies on co-infections concentrate on one of the infecting species, an immune function or group of cells and often focus on the initial phase of the infection. Here, we used a combination of experiments and mathematical modelling to investigate the network of immune responses against single and co-infections with the respiratory bacterium Bordetella bronchiseptica and the gastrointestinal helminth Trichostrongylus retortaeformis. Our goal was to identify representative mediators and functions that could capture the essence of the host immune response as a whole, and to assess how their relative contribution dynamically changed over time and between single and co-infected individuals. Network-based discrete dynamic models of single infections were built using current knowledge of bacterial and helminth immunology; the two single infection models were combined into a co-infection model that was then verified by our empirical findings. Simulations showed that a T helper cell mediated antibody and neutrophil response led to phagocytosis and clearance of B. bronchiseptica from the lungs. This was consistent in single and co-infection with no significant delay induced by the helminth. In contrast, T. retortaeformis intensity decreased faster when co-infected with the bacterium. Simulations suggested that the robust recruitment of neutrophils in the co-infection, added to the activation of IgG and eosinophil driven reduction of larvae, which also played an important role in single infection, contributed to this fast clearance. Perturbation analysis of the models, through the knockout of individual nodes (immune cells), identified the cells critical to parasite persistence and clearance both in single and co-infections. Our integrated approach captured the within-host immuno-dynamics of bacteria-helminth infection and identified key components that can be crucial for explaining individual variability between single and co-infections in natural populations
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