La prescripción adquisitiva de dominio en el sistema jurídico peruano: una revisión sistemática de la literatura científica del 2015-2019

A través de este trabajo de investigación se busca analizar de manera analítica la institución de la prescripción adquisitiva de dominio en el Perú, las dificultades a nivel jurídico que afronta el poseedor que busca afianzar su derecho cumpliendo los requisitos establecidos por el art. 950 del Código Civil, por ello planteamos la pregunta de investigación: ¿Protege al usucapiente el sistema jurídico peruano en el proceso de la prescripción adquisitiva de dominio? El objetivo de la investigación es identificar los aportes jurídicos de diversos países y autores, para lo cual se examinaron fuentes de información como Google Académico, Vez y Metabuscador, en un intervalo de tiempo del 2015 a 2019, en idioma español obteniendo 18 publicaciones. Durante la selección se utilizó el método de análisis y síntesis, cuyos resultados fueron importantes para nuestra investigación, pese a las limitaciones en revistas jurídicas, cantidad de publicaciones

Erratum to: Methods for evaluating medical tests and biomarkers

[This corrects the article DOI: 10.1186/s41512-016-0001-y.]

Evidence synthesis to inform model-based cost-effectiveness evaluations of diagnostic tests: a methodological systematic review of health technology assessments

Background: Evaluations of diagnostic tests are challenging because of the indirect nature of their impact on patient outcomes. Model-based health economic evaluations of tests allow different types of evidence from various sources to be incorporated and enable cost-effectiveness estimates to be made beyond the duration of available study data. To parameterize a health-economic model fully, all the ways a test impacts on patient health must be quantified, including but not limited to diagnostic test accuracy. Methods: We assessed all UK NIHR HTA reports published May 2009-July 2015. Reports were included if they evaluated a diagnostic test, included a model-based health economic evaluation and included a systematic review and meta-analysis of test accuracy. From each eligible report we extracted information on the following topics: 1) what evidence aside from test accuracy was searched for and synthesised, 2) which methods were used to synthesise test accuracy evidence and how did the results inform the economic model, 3) how/whether threshold effects were explored, 4) how the potential dependency between multiple tests in a pathway was accounted for, and 5) for evaluations of tests targeted at the primary care setting, how evidence from differing healthcare settings was incorporated. Results: The bivariate or HSROC model was implemented in 20/22 reports that met all inclusion criteria. Test accuracy data for health economic modelling was obtained from meta-analyses completely in four reports, partially in fourteen reports and not at all in four reports. Only 2/7 reports that used a quantitative test gave clear threshold recommendations. All 22 reports explored the effect of uncertainty in accuracy parameters but most of those that used multiple tests did not allow for dependence between test results. 7/22 tests were potentially suitable for primary care but the majority found limited evidence on test accuracy in primary care settings. Conclusions: The uptake of appropriate meta-analysis methods for synthesising evidence on diagnostic test accuracy in UK NIHR HTAs has improved in recent years. Future research should focus on other evidence requirements for cost-effectiveness assessment, threshold effects for quantitative tests and the impact of multiple diagnostic tests

Erratum to: Methods for evaluating medical tests and biomarkers

[This corrects the article DOI: 10.1186/s41512-016-0001-y.]

Prevalencia del derecho usucapiente frente al tercero adquiriente de buena fe registral en Puente Piedra, 2021

La presente tesis tuvo como objetivo principal determinar cómo se interpreta, la prevalencia del derecho de usucapiente frente al tercero adquiriente de buena fe registral en Puente Piedra, 2021. El tipo de investigación fue tipo básica, de enfoque cualitativo, diseño no experimental y de nivel descriptivo. La recolección de información se obtuvo mediante la técnica de entrevista, encuesta y análisis documental. La población, utilizada para el desarrollo de los objetivos planteados consta de casaciones emitidas por el Poder Judicial, pobladores del Centro Poblado Zapallal y especialistas en materia civil. Los resultados obtenidos señalan que la prevalencia del derecho usucapiente se interpreta, a través del cumplimiento de los requisitos legales de la posesión, y el tercero de buena fe registral invoca su derecho en el registro formal y en la aplicación de la buena fe registral. Esta investigación concluye, que la prevalencia del derecho usucapiente se interpreta en base a la posesión continua, pacífica y publica, a pesar que el poseedor no cuente con una sentencia de prescripción adquisitiva de dominio o que se encuentre aún en proceso judicial y que la inaplicación de la buena fe del tercero registral se configura porque la buena fe no es de carácter absoluto

Erratum to: Methods for evaluating medical tests and biomarkers

The original MEMTAB Abstracts in Diagnostic and Prognostic Research contains the incorrect year on individual abstracts in the PDF [1].“Diagnostic and Prognostic Research 2016” under the correspondence line should therefore have been written as “Diagnostic and Prognostic Research 2017” as the journal did not launch until 2017

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population