A High Throughput Lab-On-A-Chip System for Label Free Quantification of Breast Cancer Cells under Continuous Flow

This paper presents an LOC system combining microfluidic DEP channel with a CMOS image sensor for label and lens free detection and real-time counting of MCF-7 cells under continuous flow. Trapped and then released MCF-7 cells are accurately detected and counted under flow with a CMOS image sensor integrated underneath the DEP channel, for the first time in the literature. CMOS image sensor can capture 391 frames per second (fps) that allows detection of the released cells flowing through the channel with a flow rate up to 130 mu l/min (0.468 m/s). Therefore, the proposed system is able to detect the cells under high flow where conventional techniques for cell quantification such as fluorescent tagging become unusable. Detected cells are automatically counted with a computer program and the counting accuracy of the whole system is 95%. (C) 2016 The Authors. Published by Elsevier Ltd

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Theoretical determination of maximum biodiesel blend ratios according to kinematic viscosity values

European Biotechnology Conference -- MAY 05-07, 2016 -- LATVIAWOS: 000380240300146

Dynamic resistance nonuniformity compensation circuit for uncooled microbolometer detector arrays

This paper presents a new approach for compensating resistance nonuniformity of uncooled microbolometers by adjusting the bias currents of both detector and reference pixels. Contrary to conventional nonuniformity compensation circuits, this approach eliminates the need for digital-to-analog converters (DACs), which usually occupy a large area, dissipate high power, and require complicated external circuitry with high frequency data transfer to the microbolometer chip. The proposed circuit uses a feedback structure that dynamically changes the bias currents of the reference and detector pixels and does not need complicated external circuitry. A special feature of the circuit is that it provides continuous compensation for the detector and reference resistances due to temperature changes over time. The circuit is implemented in a 0.6 mu m 5V CMOS process and occupies an area of only 160 mu m x 630 mu m. Test results of the prototype circuit show that the circuit reduces the offset current due to resistance nonuniformity about 2.35% of its uncompensated value, i.e., an improvement of about 42.5 times is achieved, independent of the nonuniformity amount. The circuit achieves this compensation in 12 mu sec. Considering its simplicity and low cost, this approach is suitable for large array commercial infrared imaging systems

Preparation of fuels by cracking of different plastics and their blends with diesel fuel

European Biotechnology Congress -- MAY 16-18, 2013 -- Comenius Univ, Bratislava, SLOVAKIAWOS: 000323298100083…European Biotechnol Themat Network Assoc (EBTNA), Comenius Univ, Fac Nat Sc

Enlarging Characteristics of Four Nickel-Titanium Rotary Instrument Systems under Standardized Conditions of Operator-related Variables

NRC publication: Ye

Investigation the fuel properties of apricot kernel biodiesel and diesel-biodiesel fuel blends

European Biotechnology Congress -- APR 26-28, 2018 -- Athens, GREECEWOS: 000454825900091

Effect of bioethanol blending with gasoline on emissions characteristics with spark plug alteration for SI engine

European Biotechnology Congress -- APR 26-28, 2018 -- Athens, GREECEWOS: 000454825900293