Serum and peritoneal fluid levels of ischemia modified albumin in moderate/severe endometriosis

Background: Recently, the role of oxidative stress in progression of endometriosis has been reported. Ischemia-modified albumin (IMA) is a marker of protein oxidation and very limited number of studies has evaluated the role of IMA in endometriosis. This study was designed to evaluate the serum and peritoneal fluid IMA levels in moderate/severe endometriosis as a marker for oxidative stress.Methods: This study was designed as a prospective controlled clinical trial. The study group consisted of 35 cases who underwent laparoscopy and with a diagnosis of moderate/severe endometriosis. The control group (n=35) was cases without endometriosis that underwent laparoscopy for tubal sterilization. The serum and peritoneal fluid IMA levels were measured spectrophotometrically by colorimetric method with complex of albumin non-binding cobalt and dithioerthreitol.Results: Although the median serum IMA levels in study and control groups were similar (p=0.553), the levels of peritoneal fluid IMA were significantly higher in study group (p=0.044). In endometriosis cases with dysmenorrhea peritoneal fluid IMA levels were much higher than cases without dysmenorrhea (p=0.018).Conclusions: The increased levels of IMA in peritoneal fluid of endometriosis support the possible role of oxidative stress in endometriosis. With this study, peritoneal fluid IMA levels are initially documented in endometriosis cases

Dynamic crack arrest analysis by ordinary state-based peridynamics

Dynamic fracture analysis for the crack arrest phenomenon is performed by ordinary state-based peridynamics formulation and discretization employing transition bond concept. Double cantilever beam specimen is chosen for our numerical evidence purpose. The analysis consists of two main phases namely, generation and application (prediction) phases. In the generation phase, the dynamic stress intensity factors of propagating and arrested cracks are estimated by the present formulation for given crack path histories, and good agreement is achieved. As for the application phase, dynamic stress intensity factors well as total crack lengths after crack arrests are in good agræment with the experiments. Moreover, the influence of transition bond concept on the crack arrest behavior is investigated and it is found that the transition bond is very efficient in the simulation of the crack arrest problem such that premature arrests of cracks are observed without transition bond cases

Mechanical analyses of flat sheet water treatment membranes

In this work, we address the mechanical response of the flat sheet polymeric water treatment membranes under the assumed operational loading conditions. Firstly, we perform quasi-static analyses of the membranes under normal pressure loads, which is the condition that resembles the actual loading for flat sheet membranes in the submerged membrane bioreactors. Then, the long-term deformation of the membranes is studied under the assumed filtration durations for the same loading conditions by utilizing the viscoelastic material models. The quasi-static and viscoelastic membrane simulations are performed by a commercial finite element code ANSYS. Finally, the mechanical fatigue life predictions are carried out based on the stress distributions from the quasi-static analyses and the long-term effects from the viscoelastic analyses

Fatigue crack prediction in ceramic material and its porous media by using peridynamics

Peridynamics is a nonlocal reformulation of the classical continuum mechanics using integro-differential equations. Since the integro-differential equations used in peridynamics are valid in both continuous and discontinuous models, the theory is suitable for predicting progressive damages. In this study, fatigue crack growth in a ceramic material and its porous media is predicted by using the peridynamic model for fatigue cracking. First, the fatigue crack propagation in compact specimen of a non-porous ceramic material is considered. The predicted fatigue crack growth rate is compared with experimental results. Next, the fatigue crack growths in ceramic material with different porosity levels are investigated. The fatigue crack growth rate of porous materials is compared with the non-porous material to analyse the effects of porosity on fatigue crack growth. A linear relation between the relative change of fatigue crack growth rate, stress intensity factor range and porosity level is obtained by using linear regression analysis

Modelling of Eulerian incompressible fluid flows by using peridynamic differential operator

This study presents a novel method for modelling of Eulerian incompressible fluid flow by using peridynamic differential operator. The peridynamic differential operator is used to calculate partial derivatives in the Navier-Stokes equations. The pressure Poisson equation is used to obtain the pressure field whereas the velocity field is obtained by solving momentum equations. The numerical procedure to solve Navier-Stokes equations in peridynamics for the incompressible fluid is also provided. The capability of the proposed peridynamic incompressible fluid model is demonstrated by considering problems of two-dimensional cavitation, a flow inside an open channel, and a flow over a cylinder. Moreover, to demonstrate the capabilities of the proposed model, the problems of two-dimensional cavitation and a flow over a cylinder are investigated for different Reynolds numbers. The vortex shedding is also captured for the problem of a flow over a cylinder at Reynolds number of 푅푒 = 100. For verification purposes, the peridynamic results are compared with the results obtained by ANSYS Fluent, a commercial fluid dynamics software

Discutindo a educação ambiental no cotidiano escolar: desenvolvimento de projetos na escola formação inicial e continuada de professores

A presente pesquisa buscou discutir como a Educação Ambiental (EA) vem sendo trabalhada, no Ensino Fundamental e como os docentes desta escola compreendem e vem inserindo a EA no cotidiano escolar., em uma escola estadual do município de Tangará da Serra/MT, Brasil. Para tanto, realizou-se entrevistas com os professores que fazem parte de um projeto interdisciplinar de EA na escola pesquisada. Verificou-se que o projeto da escola não vem conseguindo alcançar os objetivos propostos por: desconhecimento do mesmo, pelos professores; formação deficiente dos professores, não entendimento da EA como processo de ensino-aprendizagem, falta de recursos didáticos, planejamento inadequado das atividades. A partir dessa constatação, procurou-se debater a impossibilidade de tratar do tema fora do trabalho interdisciplinar, bem como, e principalmente, a importância de um estudo mais aprofundado de EA, vinculando teoria e prática, tanto na formação docente, como em projetos escolares, a fim de fugir do tradicional vínculo “EA e ecologia, lixo e horta”.Facultad de Humanidades y Ciencias de la Educació

A Comparison of Problem Behavior Profiles in Turkish

Comparación de perfiles de conducta problemática en niños turcos con TDAH y niños sin TDAH Selda Ozdemir Special Education Department, Gazi University, Ankara Resultados: El análisis de los resultados del CBCL refleja que los niños turcos con DA/DH se situaban en los rangos clínicos en comparación con los niños sin DA/DH. Los padres de los niños con los trastornos señalaron tasas altas de comportamiento agresivo, problemas de atención y problemas con el cumplimiento de normas. Discusión y Conclusiones: En general, los resultados apuntan similitudes en las características de los niños con TDAH. En este sentido, los niños turcos con TDAH presentan niveles clínicos en cuanto a problemas de conducta en comparación con los otros niños que no tienen este trastorno. Los resultados se discuten bajo el marco de la literatura disponible y se proporcionan recomendaciones para una práctica adecuada

Peer Functioning in Children with AD/HD: A Review of Current Understanding and Intervention Options

oai:ojs.cie.asu.edu:article/16Research has consistently documented children with attention deficit/hyperactivity disorder (AD/HD) have significant problems in peer relations and strongly rejected by their typically developing peers. There is a growing recognition that traditional interventions, such as social skills trainings are no longer sufficient to address the staggering social needs of children with AD/HD. This paper introduces new directions in interventions for children with AD/HD and advocates that multi-component interventions can be highly beneficial to ameliorate the social problems of children with the disorder. Studies examining the peer relations in children with AD/HD are reviewed and available interventions are explored. In addition, problems with the application of various interventions are discussed and suggested practices are presented