478 research outputs found
High performance computing for a 3-D optical diffraction tomographic application in fluid velocimetry
Optical Diffraction Tomography has been recently introduced in fluid velocimetry to provide three dimensional information of seeding particle locations. In general, image reconstruction methods at visible wavelengths have to account for diffraction. Linear approximation has been used for three-dimensional image reconstruction, but a non-linear and iterative reconstruction method is required when multiple scattering is not negligible. Non-linear methods require the solution of the Helmholtz equation, computationally highly demanding due to the size of the problem. The present work shows the results of a non-linear method customized for spherical particle location using GPU computing and a made-to-measure storing format
Comparative study of real-time pcr (Taqman probe and sybr green), serological techniques (elisa, ifa and dat) and clinical signs evaluation, for the diagnosis of canine leishmaniasis in experimentally infected dogs
Canine leishmaniasis (CanL) diagnosis is not fully resolved. Currently, two specific methodologies are in continuous development, the detection of the parasite DNA or RNA in target organs and the detection of specific antibodies against Leishmania sp. For a correct diagnosis, it has been shown that the joint use of this type of test is necessary. In this work, a Sybr Green and a TaqMan Probe based on real time PCRs (qPCR) was performed for the detection of Leishmania sp. in order to correlate the results with clinicopathological and serological evaluations (IFA, ELISA and DAT) to propose an optimal biological sample to be used to detect the parasite in both early and late stages of the infection. A total of four samples were processed: conjunctival swabs, popliteal lymph node aspirates, bone marrow aspirates, and peripheral blood from experimentally infected dogs belonging to a larger study. Our results indicated that a single non-invasive sample (conjunctival swab) and the application of both types of qPCR would be reliable for determining Leishmania infection as well as the disease stage in dogs, thus avoiding bone marrow, lymph node aspirate or blood samples collection. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/)
Paleopatología en la necrópolis mudéjar de El Raval (Crevillent, Alicante)
X Congreso Nacional de Paleopatología. Univesidad Autónoma de Madrid, septiembre de 200
Software público, libre, abierto, gratuito, privativo y comercial para la innovación y mejora de la calidad en la docencia, investigación, gestión y asistencia
The public free software (now renamed as open software) is the basis of the open source software (OSS) project. This initiative promotes the use of open standards and platform-independent accessibility. Many OSS products are free or low cost, which allows their deployment even in the absence of large economic resources (developing countries, schools, etc.). Besides, their source code can be modified, adapted and optimized by anyone, since it is public. Nevertheless, the OSS may also have drawbacks. Thus, its development may not be as orderly and hierarchical as the privative software is, and may not have an appropriate funding. This may jeopardize the ease of use and coherence of the final product, increasing the transition, training and technical support costs. Besides, it must be taken into account that there is also commercial open software, as well as free privative software. In any case, the excellence of the software may be independent of such variables. Thus, the best strategy is the coexistence and free competition of all kinds of software. This will allow a quality improvement and an innovation enhancement, which will benefit the education, research, management and assistance at the university in particular and at the whole society in general.El software público libre es el fundamento del movimiento de software de fuente abierta (OSS). Éste puede facilitar el uso de estándares abiertos, con accesibilidad independiente de plataforma informática. El bajo coste o gratuidad de muchos productos OSS permite su implantación cuando los recursos económicos son escasos (países en desarrollo, escuelas, etc.). Además, su código se puede modificar, adaptar y mejorar por cualquiera, ya que es público. No obstante, el OSS también puede presentar inconvenientes. Así, su desarrollo puede no ser tan ordenado y jerárquico como el del software privativo y puede no tener una financiación apropiada. De este modo, puede verse comprometida la facilidad de uso y coherencia del producto final. Ello puede incrementar los costes de transición, entrenamiento y soporte técnico. Por otra parte, conviene recordar que existe software libre comercial y software privativo gratuito. En cualquier caso, la excelencia del software puede ser independiente de dichas variables. Por tanto, la mejor estrategia es la coexistencia y libre competencia de todo tipo de software. Así se puede conseguir una mejora de calidad y una potenciación de la innovación, que beneficie a la docencia, investigación, gestión y asistencia universitarias en particular, así como a la sociedad en general
Particulate air pollution and health effects for cardiovascular and respiratory causes over an industrial neighborhood; Linking epidemiological time series studies and the power of a health perception survey
Talcahuano and Hualpén counties are one of the most highly industrial-polluted coastal zones in Chile, overhanging the iron foundry industry, coal burning power plants, chemical industry, and petroleum refinery, etc. The relationship between air pollution from PM2.5 measured at the Libertad monitoring station and health effects as the daily number of deaths and hospital admissions, for specific cardiovascular and respiratory diseases were studied. The results were compared with a health perception survey applied to the local population during spring 2008. Significant statistical associations were found between daily mortality and morbidity in Talcahuano-Hualpén area for cardiovascular and respiratory diseases and daily PM2.5 concentration, coinciding with the health perception of the inhabitants from these counties. The results suggest that point sources may be responsible for increased mortality in that industrial area. This has an important implication in relation with the size and chemical composition of the particles, but also for monitoring and control strategies. This is an abstract of a paper presented at the 103rd AWMA Annual Conference and Exhibition (Alberta, Canada 6/22-25/2010)
Aids in Spain: Incidence by autonomous communities, transmission rules and sex (1981-1998)
Fundamentos: Analizar la velocidad de aparición de SIDA y su evolución a lo largo de los años en España, por
Comunidades Autónomas, enfermedades indicativas referidas y por vía de transmisión y sexo.
Método: Estudio epidemiológico, longitudinal, descriptivo, de morbilidad por SIDA en España durante el periodo
1981-1998. Se calcula la tasa de incidencia como indicador sanitario.
Resultados: Desde la aparición de SIDA en España en 1981 la tasa de incidencia ha ido aumentando hasta alcanzar
en 1994, valores de 183.6 casos por millón de habitantes. Las vías de transmisión más importantes son: adictos
a drogas vía parenteral (59%), transmisión heterosexual (21%) y transmisión homosexual (12%).
Conclusiones: La incidencia está disminuyendo en los últimos años, fundamentalmente debida a los avances en la
terapia antirretroviral. Esta disminución se observa en todas las vías de transmisión. El mayor número de casos
en hombres (79%) que en mujeres, se debe, sobretodo por la transmisión en relaciones homosexuales y al uso de
drogas por vía parenteral mayoritario en varones. No obstante, el porcentaje de mujeres está aumentando, debido
a que a partir de 1994 la segunda vía de transmisión pasa a ser las relaciones heterosexuales en lugar de las
homosexuales.Background: To analyse incidence of AIDS in Spain, by Autonomous Communities, transmission rules and sex.
Methods: Epidemiological study, descriptive, of morbidity by AIDS in Spain from 1981 to 1998. We calculate incidence
rate like indicator sanitary of morbidity by AIDS.
Results: Since AIDS appeared in Spain in 1981, incidence rate of AIDS in Spain has been increasing until 1994, value
183.6 cases per million of habitants. The rules of transmission more important are: parenteral in addicted to drugs
(59%), heterosexual (21%) and homosexual (12%).
Conclusions: Incidence has decreasing in the last years, because the new treatment of retroviral drugs. Men are most
important infection (79%) than women; this is due to transmission homosexual and addicted to parenteral drugs that
were more important in men. Since 1994 the second transmission rule is heterosexual transmission which is higher
than homosexual
La innovación del modelo de negocio bancario: el reto de la banca digital
La aparición de la Nueva Economía y de las FinTech ha supuesto un cambio de operativa en el sector bancario. Esto, junto al impacto de la crisis financiera internacional de 2008, justifica el interés por reflexionar sobre el reto tecnológico al que se enfrenta para lograr adaptarse a los cambios del entorno, generando nuevas ventajas competitivas basadas en innovación. El objetivo de la comunicación es analizar la evolución del sector, junto a la necesidad de implantar el nuevo enfoque de innovación del modelo de negocio, proponiendo una "cadena de valor innovadora" basada en las perspectivas de la RSC y de la "economía colaborativa"2017-1
Educación y cooperación para el desarrollo mediante estándares universales de accesibilidad
II FORO «IBEROAMÉRICA EN LA ESCENA ECONÓMICA INTERNACIONAL: INVERSIONES Y EDUCACIÓN PARA EL DESARROLLO». UNIVERSIDAD REY JUAN CARLOS, MADRID (ESPAÑA), 14 DE DICIEMBRE DE 200
Tuning Proton Conductivity in Alkali Metal Phosphonocarboxylates by Cation Size-Induced and Water-Facilitated Proton Transfer Pathways
The structural and functional chemistry of a family of alkali-metal ions with racemic R,S-hydroxyphosphonoacetate (M-HPAA; M = Li, Na, K, Cs) are reported. Crystal structures were determined by X-ray data (Li+, powder diffraction following an ab initio methodology; Na+, K+, Cs+, single crystal). A gradual increase in dimensionality directly proportional to the alkali ionic radius was observed. [Li3(OOCCH(OH)PO3)-(H2O)4]·H2O (Li-HPAA) shows a 1D framework built up by Li-ligand “slabs” with Li+ in three different coordination environments (4-, 5-, and 6-coordinated). Na-HPAA, Na2(OOCCH(OH)PO3H)(H2O)4, exhibits a pillared layered “house of cards” structure, while K-HPAA, K2(OOCCH(OH)PO3H)(H2O)2, and Cs-HPAA, Cs(HOOCCH(OH)-PO3H), typically present intricate 3D frameworks. Strong hydrogen-bonded networks are created even if no water is present, as is the case in Cs-HPAA. As a result, all compounds show proton conductivity in the range 3.5 × 10−5 S cm−1 (Cs-HPAA) to 5.6 × 10−3 S cm−1 (Na-HPAA) at 98% RH and T = 24 °C. Differences in proton conduction mechanisms, Grothuss (Na+ and Cs+) or vehicular (Li+ and K+), are attributed to the different roles played by water molecules and/or proton transfer pathways between phosphonate and carboxylate groups of the ligand HPAA. Upon slow crystallization, partial enrichment in the S enantiomer of the ligand is observed for Na-HPAA, while the Cs-HPAA is a chiral compound containing only the S enantiomer.Proyectos nacionales MAT2010-15175 y MAT2013-41836-
Accesibilidad a Internet: requisitos para la calidad en la docencia e investigación
A good Internet platform for teaching and research must be accessible, independently of the computer platform used, language and other peculiarities (personal or external). This work analyzes the current limitations of Internet access, as well as the potentialities that would represent an access being truly independent of the computer platform, discapacities, availability and speed of access, language and legislation. Thus, the benefits for a more accesible network for lecturing and investigation, overcoming the geographic location or possible discapacity, would be immediate and would have a broad impact spectrum. A more accesible Internet would enhace not only the dissemination of the information, approaching us to the 'global village', but also others aspects like university principles and values that sould be considered: an improvement of the equality of opportunities and the access to the culture and the education, that are the basis of the progress and the individual and collective liberties.Una buena plataforma de docencia e investigación en la red debe ser accesible, independientemente del entorno informático, idioma y condicionantes( personales o externos). Es este trabajo se analizan, por una parte, las limitaciones actuales que se presentan en el acceso a Internet, y por otra las potencialidades que tendría un acceso un acceso independiente de las plataforma informáticas, discapacidades, disponibilidad y velocidad de acceso, idioma y legislación. Así, los beneficios para la docencia y la investigación de una red más accesible, por encima de la localización geográfica o posible discapacidad, serán inmediatos y redundaría en otros campos. Una Internet más accesible abriría una nueva vía no sólo para la difusión de la información, acercándonos a la 'aldea global', sino también para otros aspectos de lo que entenderemos como principios y valores universitarios y que deben ser considerados: una mejora en la igualdad de oportunidades y en el acceso a la cultura y la formación, que son las bases del progreso y de las libertades tanto individuales como colectivas
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