Adult Attachment, Conflict Resolution Style and Relationship Quality among Spanish Young-adult Couples

The evidence of the interrelationships between adult attachment, conflict resolution style and relationship quality in couple relationships shows some inconsistencies and it is mostly based on English-speaking adult samples, as well as on individuals’ rather than on both couple members’ reports. Therefore, the aim was to examine the associations between adult attachment, conflict resolution style and relationship quality from a dyadic approach. A sample of 405 heterosexual young couples completed online the brief version of the Experiences in Close Relationships-Revised Questionnaire, the respondent version of the Conflict Resolution Styles Inventory, and a 4-item measure of relationship quality. Avoidance attachment showed a stronger negative correlation than anxiety with relationship quality. Withdrawal and conflict engagement styles were more highly correlated with avoidance and anxiety, respectively. At a dyadic level, relationship quality was negatively predicted by actor avoidance attachment and positively predicted by partner relationship quality. No actor or partner effects of conflict resolution style on relationship quality were observed. Overall, partners with higher attachment anxiety and avoidance reported more dysfunctional conflict resolution styles and less satisfaction with the relationship

Water Stress Enhances the Progression of Branch Dieback and Almond Decline under Field Conditions

Branch dieback and tree decline have been described as a common complex disease worldwide in woody crops, with Botryosphaeriaceae and Diaporthaceae being considered the most frequent fungi associated with the disease symptoms. Their behaviour is still uncertain, since they are considered endophytes becoming pathogenic in weakened hosts when stress conditions, such as water deficiency occur. Therefore, the main goal of this study was to determine if water stress enhances general decline on weakened almond trees subjected to different irrigation treatments under natural field conditions. In parallel, the occurrence of fungal species associated with almond decline was also determined in relation to disease progression by fungal isolation, and morphological and molecular based-methods. The symptoms of branch dieback and general decline were observed over time, mainly in the experimental plots subjected to high water deficiency. Botryosphaeriaceae were the most consistently isolated fungi, and Botryosphaeria dothidea was the most frequent. Collophorina hispanica was the second most frequent species and Diaporthe and Cytospora species were isolated in a low frequency. Most of them were recovered from both asymptomatic and symptomatic trees, with their consistency of isolation increasing with the disease severity. This work reveals the need to elucidate the role of biotic and abiotic factors which increase the rate of infection of fungal trunk pathogens, in order to generate important knowledge on their life cycle

Turismo fronterizo: conceptualización y consideraciones en torno a su desarrollo

El turismo se configura como uno de los principales sectores económicos a nivel mundial, generando importantes beneficios para los destinos. El objetivo de este artículo es realizar una revisión de la literatura científica sobre el turismo fronterizo, con la finalidad de conocer cuáles son sus características, fortalezas y debilidades de su desarrollo, para establecer, posteriormente, futuras líneas de investigación. En este contexto, se da respuesta a la necesidad que existe en los diferentes campos científicos de realizar una periódica revisión de la literatura existente y, por este motivo, son diversas las investigaciones en turismo que realizan revisiones de la literatura para conocer la situación sobre un tema turístico determinado. Las fuentes de recolección de datos han sido secundarías, todas ellas provenientes de trabajos científicos publicados en revistas.Tourism is configured as one of the main economic sectors worldwide, generating significant benefits for destinations. The aim of this article is to review the scientific literature on the border tourism, in order to know what their characteristics, strengths and weaknesses of their development, to establish subsequently future research. In this context, it responds to the need that exists in the various scientific fields for periodic review of existing literature and, for this reason, they are diverse investigations tourism conducting literature reviews to know the situation on a certain tourist theme. The sources of data collection have been secondary, all from scientific papers published in journals

Transcervical carotid stenting with internal carotid artery flow reversal: Feasibility and preliminary results

ObjectiveTransfemoral carotid artery stenting (CAS), with or without distal protection, is associated with risk for cerebral and peripheral embolism and access site complications. To establish cerebral protection before crossing the carotid lesion and to avert transfemoral access complications, the present study was undertaken to evaluate a transcervical approach for CAS with carotid flow reversal for cerebral protection.MethodsFifty patients underwent CAS through a transcervical approach. All patients with symptoms had greater than 60% internal carotid artery (ICA) stenosis, and all patients without symptoms had greater than 80% ICA stenosis. Twenty-one patients (42%) had symptomatic disease or ipsilateral stroke, and 8 patients (16%) had contralateral stroke. Four patients (8%) had recurrent stenosis, 7 patients (14%) had contralateral ICA occlusion, and 1 patient (2%) had undergone previous neck radiation. Twenty-seven procedures (54%) were performed with local anesthesia, and 23 (46%) with general anesthesia. Using a cervical cutdown, flow was reversed in the ICA by occluding the common carotid artery and establishing a carotid–jugular vein fistula. Pre-dilation was selective, and 8-mm to 10-mm self-expanding stents were deployed and post-dilated with 5-mm to 6-mm balloons in all cases.ResultsThe procedure was technically successful in all patients, without significant residual stenoses. No strokes or deaths occurred. There was 1 wound complication (2%). All patients were discharged within 2 days of surgery. Mean flow reversal time was 21.4 minutes (range, 9-50 minutes). Carotid flow reversal was not tolerated in 2 patients (4%). Early in the experience, carotid flow reversal was not possible in 1 patient, and there were 1 major and 3 minor common carotid artery dissections, which resolved after stent placement. One intraoperative transient ischemic attack (2%) occurred in 1 patient in whom carotid flow was not reversed, and 1 patient with a contralateral ICA occlusion had a contralateral transient ischemic attack. At 1 to 12 months of follow-up, all patients remained asymptomatic, and all but 1 stent remained patent.ConclusionTranscervical CAS with carotid flow reversal is feasible and safe. It can be done with the patient under local anesthesia, averts the complications of the transfemoral approach, and eliminates the increased complexity and cost of cerebral protection devices. Transcervical CAS is feasible when the transfemoral route is impossible or contraindicated, and may be the procedure of choice in a subset of patients in whom carotid stenting is indicated

Nuevo sistema de predicción de dificultad en la ventilación a través de dispositivos supraglóticos

The aim of this study was to propose and validate a new clinical score to predict difficult ventilation through a supraglottic airway device.The authors developed a scoring system that was prospectively validated in 5532 patients. They assigned point values to each of the identified four risk factors: male, age >45 yr., short thyromental distance, and limited neck movement, their sum composing the score. The score ranged between 0 and 7 points. A score 4 or greater is associated with an increased risk of difficult ventilation through a supraglottic airway device. Our conclusion is that the new score for prediction of difficult ventilation through a supraglottic airway device is easy to use and could help anesthetists plan for difficult airway management.El objetivo de este estudio fue proponer y validar un nuevo sistema de puntuación clínica para predecir la dificultad de ventilación a través de un dispositivo supraglótico (DSG). Los autores desarrollaron un score que se validó prospectivamente en 5532 pacientes. Se asignaron valores numéricos a cada uno de los 4 factores de riesgo que se identificaron: varón, mayor de 45 años, distancia tiromentoniana (DTM) corta y movilidad cervical limitada, y su suma compuso el score. El rango de dicho score va de 0 a 7 puntos. Un score de 4 o mayor se asocia a un riesgo incrementado de dificultad de ventilación a través de DSG. Nuestra conclusión es que el nuevo score para predicción de dificultad de ventilación a través de dispositivos supraglóticos es fácil de usar y podría ayudar en el plan de manejo de la VAD por los anestesiólogos.

Proteomic characterization of human coronary thrombus in patients with ST-segment elevation acute myocardial infarction

Acute myocardial infarction with ST-segment elevation (STEMI) initiates with intraluminal thrombosis and results in total occlusion of the coronary artery. To date, characterization of the coronary thrombus proteome in STEMI patients has not been yet accomplished. Therefore, we aimed to perform an in-depth proteomic characterization of the human coronary thrombus by means of three different approaches: 2-DE followed by mass spectrometry (MALDI MS/MS), 1-DE combined either with liquid chromatography coupled to mass spectrometry in a MALDI TOF/TOF (LC-MALDI-MS/MS), or in a LTQ-Orbitrap (LC-ESI-MS/MS). This approach allowed us to identify a total of 708 proteins in the thrombus. Expression in coronary thrombi (n=20) of 14 proteins was verified, and the expression of fibrin and 6 cell markers (platelets, monocytes, neutrophils, eosinophils, T-cells and B-cells) quantified by selected reaction monitoring (SRM). A positive correlation of 5 proteins (fermitin homolog 3, thrombospondin-1, myosin-9, beta parvin and ras-related protein Rap-1b) with CD41 was found, pointing out the potential activation of a focal adhesion pathway within thrombus platelets. DIDO1 protein was found to correlate negatively with thrombus fibrin, and was found up-regulated in the plasma of these STEMI patients, which may constitute a starting point for further analyses in the search for biomarkers of thrombosis. BIOLOGICAL SIGNIFICANCE: The proteomic characterization of the human coronary thrombus may contribute to a better understanding of the mechanisms involved in acute coronary syndrome, and thus pave the road for the identification of new therapeutic targets that may help addressing this and other thrombotic diseases. A novel methodology to characterize thrombus composition and expression of a sub-group of proteins is hereby described, which allowed linking protein expression with cellular and ECM matrix composition of the thrombus. Five proteins (fermitin homolog 3, thrombospondin-1, myosin-9, beta parvin and ras-related protein Rap-1b) co-express within the human coronary thrombus with CD41, pointing out the potential activation of a focal adhesion pathway within thrombus platelets during thrombus formation. Besides, the protein death-inducer obliterator 1, found to be expressed within the human coronary thrombus, has been proved to increase in the plasma of STEMI patients, which constitutes an important starting point for further analyses in the search for biomarkers of thrombosis.This work was supported by grants from the Instituto de Salud Carlos III (FIS PI070537, PI11/02239), Fondos Feder, Redes temáticas de Investigación Cooperativa en Salud (RD12/0042/ 0071, RD06/0014/1015), and Fundación para la Investigación Sanitaria de Castilla-La Mancha (FISCAM PI2008-08, PI2008-28, PI2008-52). These results are lined up with the Spanish initiative on the Human Proteome Project (SpHPP). The CNIC is supported by the Spanish Ministerio de Economia y Competitividad and the Fundacion Pro-CNIC. We would like to thank Dr. Gloria Alvarez-Llamas for her kind suggestions for the manuscript; Gemma Barroso from Proteomic Unit, Hospital Nacional de Paraplejicos, for her help and dedication to this work, as well as Veronica Moral and Ana Gallardo from the same Unit, and TamaraSastre andCarmenBermudez for their technical support.S

Association of 25-hydroxyvitamin D with Metabolic Syndrome in Patients with Psoriasis: A Case-control Study

Vitamin D deficiency is associated with higher cardiovascular risk and metabolic syndrome (MeS) criteria. The main objective of this study was to analyse the association of 25-hydroxyvitamin D (25-OHD) serum levels with MeS (National Cholesterol Education Program Adult Treatment Panel-III criteria) in 46 Spanish patients with psoriasis, but without arthritis and systemic treatment, and 46 control subjects, matched by sex and age. The patients with psoriasis showed significantly lower level of 25-OHD than controls (30.5 vs. 38.3 ng/ml; p =0.0001). Patients with MeS had significantly lower serum levels of 25-OHD than those without MeS (24.1 +/- 7.5 vs. 32.8 +/- 8.9,p =0.007), and a negative correlation was found between 25-OHD and waist circumference, diastolic blood pressure, fasting glucose, and triglyceridaemia. In the control group no significant correlation between 25-OHD and MeS was found. Although the sample was small, our results suggest a potential protective role for 25-OHD in the metabolic profile of patients with psoriasis without arthritis

El blog como metodología activa de enseñanza-aprendizaje y herramienta de adquisición de competencias en la asignatura psicología del desarrollo en edad infantil (0-6 años)

Memoria ID-328. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2013-2014