Bilateral adrenalectomy for asynchronous metastases of a malignant melanoma

Indexación: Web of Science; Scielo.Clinical case: We report a 70 years old male with a history of an ear lobe melanoma with was excised seven years ago, who had a bronchial relapse and required a right pneumonectomy. During a follow up abdominal CAT scan, a 9 cm tumor in the left adrenal gland was detected. The patient was operated, performing a left adrenalectomy and nephrectomy. The pathologic study confirmed the presence of a fusocellular melanoma. One year later, a right adrenal mass was detected and excised. The pathological study of the piece again confirmed a metastasis of a malignant melanoma. The patient died due to progression of the disease, 10 years after the adrenalectomy. Key words: Adrenal metastases, laparoscopic adrenalectomy, melanoma.Objetivo: Presentar un caso de metástasis suprarrenal bilateral asincrónica de Melanoma cutáneo tratado con adrenalectomía laparoscópica bilateral. Caso clínico: Paciente de 70 años con antecedente de melanoma del pabellón auricular extirpado 7 años antes de su consulta urológica. Posteriormente, presenta una recidiva bronquial tratada con quimioterapia, radioterapia y neumonectomía derecha. En sus exámenes de seguimiento una Tomografía computada muestra el hallazgo incidental de una lesión tumoral de 9 cm en la glándula suprarrenal izquierda. Se realizó nefrectomía y adrenalectomía izquierda laparoscópica en bloque sin incidencias. El análisis histopatológico confirmó el hallazgo de una metástasis de melanoma fuso-celular. Un año después el paciente presenta un nuevo hallazgo incidental de un tumor de 3 cm en la glándula suprarrenal derecha, la cual fue tratada con adrenalectomía laparoscópica, y cuyo análisis histopatológico demostró metástasis de melanoma maligno. El paciente fallece por progresión de su enfermedad 10 años después de su cirugía suprarrenal. Conclusiones: En los pacientes con metástasis suprarrenal de melanoma, la adrenalectomía incrementa la supervivencia cáncer especifica en relación a los pacientes tratados sin cirugía. El abordaje laparoscópico constituye una alternativa terapéutica con menor morbilidad que la cirugía abierta en cirujanos con experiencia laparoscópica. Palabras clave: Metástasis suprarrenal, adrenalectomía laparoscópica, melanoma.http://ref.scielo.org/mymgk

Coincidence measurement of residues and light particles in the reaction 56Fe+p at 1 GeV per nucleon with SPALADIN

The spallation of $^{56}$Fe in collisions with hydrogen at 1 A GeV has been studied in inverse kinematics with the large-aperture setup SPALADIN at GSI. Coincidences of residues with low-center-of-mass kinetic energy light particles and fragments have been measured allowing the decomposition of the total reaction cross-section into the different possible de-excitation channels. Detailed information on the evolution of these de-excitation channels with excitation energy has also been obtained. The comparison of the data with predictions of several de-excitation models coupled to the INCL4 intra-nuclear cascade model shows that only GEMINI can reasonably account for the bulk of collected results, indicating that in a light system with no compression and little angular momentum, multifragmentation might not be necessary to explain the data.Comment: 4 pages, 5 figures, revised version accepted in Phys. Rev. Let

What does a change in the quark condensate say about restoration of chiral symmetry in matter?

The contribution of nucleons to the quark condensate in nuclear matter includes a piece of first order in $m_\pi$, arising from the contribution of low-momentum virtual pions to the $\pi N$ sigma commutator. Chiral symmetry requires that no term of this order appears in the $NN$ interaction. The mass of a nucleon in matter thus cannot depend in any simple way on the quark condensate alone. More generally, pieces of the quark condensate that arise from low-momentum pions should not be associated with partial restoration of chiral symmetry.Comment: 9 pages (RevTeX). Definition of effective mass changed; numerical value of leading nonanalytic term corrected, along with various misprint

Spallation Residues in the Reaction 56Fe + p at 0.3, 0.5, 0.75, 1.0 and 1.5 A GeV

The spallation residues produced in the bombardment of 56}Fe at 1.5, 1.0, 0.75, 0.5 and 0.3 A GeV on a liquid-hydrogen target have been measured using the reverse kinematics technique and the Fragment Separator at GSI (Darmstadt). This technique has permitted the full identification in charge and mass of all isotopes produced with cross-sections larger than 10^{-2} mb down to Z=8. Their individual production cross-sections and recoil velocities at the five energies are presented. Production cross-sections are compared to previously existing data and to empirical parametric formulas, often used in cosmic-ray astrophysics. The experimental data are also extensively compared to different combinations of intra-nuclear cascade and de-excitation models. It is shown that the yields of the lightest isotopes cannot be accounted for by standard evaporation models. The GEMINI model, which includes an asymmetric fission decay mode, gives an overall good agreement with the data. These experimental data can be directly used for the estimation of composition modifications and damages in materials containing iron in spallation sources. They are also useful for improving high precision cosmic-ray measurements.Comment: Submited to Phys. Rev. C (10/2006

Nontrivial eigenvalues of the Liouvillian of an open quantum system

We present methods of finding complex eigenvalues of the Liouvillian of an open quantum system. The goal is to find eigenvalues that cannot be predicted from the eigenvalues of the corresponding Hamiltonian. Our model is a T-type quantum dot with an infinitely long lead. We suggest the existence of the non-trivial eigenvalues of the Liouvillian in two ways: one way is to show that the original problem reduces to the problem of a two-particle Hamiltonian with a two-body interaction and the other way is to show that diagram expansion of the Green's function has correlation between the bra state and the ket state. We also introduce the integral equations equivalent to the original eigenvalue problem.Comment: 5 pages, 2 figures, proceeding

A renormalisation group approach to two-body scattering in the presence of long-range forces

We apply renormalisation-group methods to two-body scattering by a combination of known long-range and unknown short-range potentials. We impose a cut-off in the basis of distorted waves of the long-range potential and identify possible fixed points of the short-range potential as this cut-off is lowered to zero. The expansions around these fixed points define the power countings for the corresponding effective field theories. Expansions around nontrivial fixed points are shown to correspond to distorted-wave versions of the effective-range expansion. These methods are applied to scattering in the presence of Coulomb, Yukawa and repulsive inverse-square potentials.Comment: 22 pages (RevTeX), 4 figure

Results from a Prototype Proton-CT Head Scanner

We are exploring low-dose proton radiography and computed tomography (pCT) as techniques to improve the accuracy of proton treatment planning and to provide artifact-free images for verification and adaptive therapy at the time of treatment. Here we report on comprehensive beam test results with our prototype pCT head scanner. The detector system and data acquisition attain a sustained rate of more than a million protons individually measured per second, allowing a full CT scan to be completed in six minutes or less of beam time. In order to assess the performance of the scanner for proton radiography as well as computed tomography, we have performed numerous scans of phantoms at the Northwestern Medicine Chicago Proton Center including a custom phantom designed to assess the spatial resolution, a phantom to assess the measurement of relative stopping power, and a dosimetry phantom. Some images, performance, and dosimetry results from those phantom scans are presented together with a description of the instrument, the data acquisition system, and the calibration methods.Comment: Conference on the Application of Accelerators in Research and Industry, CAARI 2016, 30 October to 4 November 2016, Ft. Worth, TX, US

SMS-Builder: An adaptive software tool for building systematic mapping studies

A Systematic Mapping Study is an instrument frequently used to carry out a search process, identification, and classification of studies in different fields. Researchers in front of this type of process have a challenge while managing the data about these studies. This paper presents a software tool that has been created to help those who need to build a systematic mapping study. In addition, this work follows the evidence-based software engineering approach and extends it through a software tool by including different ways of adapting this process