154 research outputs found
Синтез духовно-релігійного і національного в ідентифікації українського церковно-історичного процесу
Thermal Conductivity of Thermally-Isolating Polymeric and Composite Structural Support Materials Between 0.3 and 4 K
We present measurements of the low-temperature thermal conductivity of a
number of polymeric and composite materials from 0.3 to 4 K. The materials
measured are Vespel SP-1, Vespel SP-22, unfilled PEEK, 30% carbon fiber-filled
PEEK, 30% glass-filled PEEK, carbon fiber Graphlite composite rod, Torlon 4301,
G-10/FR-4 fiberglass, pultruded fiberglass composite, Macor ceramic, and
graphite rod. These materials have moderate to high elastic moduli making them
useful for thermally-isolating structural supports.Comment: Accepted for publication in the journal Cryogenic
Synchronous communication in PLM environments using annotated CAD models
The connection of resources, data, and knowledge through communication technology plays a vital role in current collaborative design methodologies and Product Lifecycle Management (PLM) systems, as these elements act as channels for information and meaning. Despite significant advances in the area of PLM, most communication tools are used as separate services that are disconnected from existing development environments. Consequently, during a communication session, the specific elements being discussed are usually not linked to the context of the discussion, which may result in important information getting lost or becoming difficult to access. In this paper, we present a method to add synchronous communication functionality to a PLM system based on annotated information embedded in the CAD model. This approach provides users a communication channel that is built directly into the CAD interface and is valuable when individuals need to be contacted regarding the annotated aspects of a CAD model. We present the architecture of a new system and its integration with existing PLM systems, and describe the implementation details of an annotation-based video conferencing module for a commercial CAD application.This work was supported by the Spanish Ministry of Economy and Competitiveness and the FEDER Funds, through the ANNOTA project (Ref. TIN2013-46036-C3-1-R).Camba, JD.; Contero, M.; Salvador Herranz, GM.; Plumed, R. (2016). Synchronous communication in PLM environments using annotated CAD models. Journal of Systems Science and Systems Engineering. 25(2):142-158. https://doi.org/10.1007/s11518-016-5305-5S142158252Abrahamson, S., Wallace, D., Senin, N. & Sferro, P. (2000). Integrated design in a service marketplace. Computer-Aided Design, 32(2):97–107.Ahmed, S. (2005). Encouraging reuse of design knowledge: a method to index knowledge. Design Studies, 26:565–592.Alavi, M. & Tiwana, A (2002). Knowledge integration in virtual teams: the potential role of KMS. Journal of the American Society for Information Science and Technology, 53:1029–1037.Ameri, F. & Dutta, D. (2005). Product lifecycle management: closing the knowledge loops. Computer-Aided Design and Applications, 2(5):577–590.Anderson, A.H., Smallwood, L., MacDonald, R., Mullin, J., Fleming, A. & O'Malley, C. (2000). Video data and video links in mediated communication: what do users value? International Journal of Human-Computer Studies, 52(1):165–187.Arias, E., Eden, H., Fischer, G., Gorman, A. & Scharff, E. (2000). Transcending the individual human mind–creating shared understanding through collaborative design. ACM Transactions on Computer-Human Interaction (TOCHI) 7(1): 84–113.Barley, W.C., Leonardi, P.M., & Bailey, D.E. (2012). Engineering objects for collaboration: strategies of ambiguity and clarity at knowledge boundaries. Human Communication Research, 38:280–308.Boujut, J.F. & Dugdale, J. (2006). Design of a 3D annotation tool for supporting evaluation activities in engineering design. Cooperative Systems Design, COOP 6:1–8.Camba, J., Contero, M., Johnson, M. & Company, P. (2014). Extended 3D annotations as a new mechanism to explicitly communicate geometric design intent and increase CAD model reusability. Computer-Aided Design, 57:61–73.Camba, J., Contero, M. & Salvador-Herranz, G. (2014). Speak with the annotator: promoting interaction in a knowledge-based CAD environment built on the extended annotation concept. Proceedings of the 2014 IEEE 18th International Conference on Computer Supported Cooperative Work in Design (CSCWD), 196–201.Chudoba, K.M., Wynn, E., Lu, M. & Watson-Manheim, M.B. (2005). How virtual are we? Measuring virtuality and understanding its impact in a global organization. Information Systems Journal, 15(4):279–306.Danesi, F., Gardan, N. & Gardan, Y. (2006). Collaborative Design: from Concept to Application. Geometric Modeling and Imaging—New Trends, 90–96.Durstewitz, M., Kiefner, B., Kueke, R., Putkonen, H., Repo, P. & Tuikka, T. (2002). Virtual collaboration environment for aircraft design. Proceedings of the IEEE 6th International Conference on Information Visualisation, 502–507.Fisher, D., Brush, A.J., Gleave, E. & Smith, M.A. (2006). Revisiting Whittaker and Sidner’s email overload ten years later. Proceedings of the 2006 20th Anniversary Conference on Computer Supported Cooperative Work. ACM, BanffFonseca, M.J., Henriques, E., Silva, N., Cardoso, T. & Jorge, J.A. (2006). A collaborative CAD conference tool to support mobile engineering. Rapid Product Development (RPD’06), Marinha Grande, Portugal.Frechette, S.P. (2011). Model based enterprise for manufacturing. Proceedings of the 44th CIRP International Conference on Manufacturing Systems.Fu, W.X., Bian, J. & Xu, Y.M. (2013). A video conferencing system for collaborative engineering design. Applied Mechanics and Materials, 344:246–252.Fuh, J.Y.H. & Li, W.D. (2005). Advances in collaborative CAD: the-state-of-the art. Computer-Aided Design, 37:571–581.Fussell, S.R., Kraut, R.E. & Siegel, J. (2000). Coordination of communication: effects of shared visual context on collaborative work. Proceedings of the 2000 ACM Conference on Computer Supported Cooperative Work, 21–30.Gajewska, H., Kistler, J., Manasse, M.S. & Redell, D. (1994). Argo: a system for distributed collaboration. Proceedings of the ACM Second International Conference on Multimedia, San Francisco, CA, USA. 433–440.Gantz, J., Reinsel, D., Chute, C., Schlichting, W., Mcarthur, J., Minton, S., Xheneti, I., Toncheva, A. & Manfrediz, A. (2007). The expanding digital universe: a forecast of worldwide information growth through 2010. IDC, Massachusetts.Gowan, Jr. J.A. & Downs, J.M. (1994). Video conferencing human-machine interface: a field study. Information and Management, 27(6):341–356.Gupta, A., Mattarelli, E., Seshasai, S. & Broschak, J. (2009). Use of collaborative technologies and knowledge sharing in co-located and distributed teams: towards the 24-h knowledge factory. The Journal of Strategic Information Systems, 18:147–161.Hickson, I. (2009). The Web Socket Protocol IETF, Standards Track.Hong, J., Toye, G. & Leifer, L.J. (1996). Engineering design notebook for sharing and reuse. Computers in Industry, 29:27–35.Isaacs, E.A. & Tang, J.C. (1994). What video can and cannot do for collaboration: a case study. Multimedia Systems, 2(2):63–73.Karsenty, L. (1999). Cooperative work and shared visual context: an empirical study of comprehension problems in side-by-side and remote help dialogues. Human Computer Interaction, 14(3): 283–315.Lahti, H., Seitamaa-Hakkarainen, P. & Hakkarainen, K. (2004). Collaboration patterns in computer supported collaborative designing. Design Studies, 25:351–371.Leenders, R.T.A., Van Engelen, J.M. & Kratzer, J. (2003). Virtuality, communication, and new product team creativity: a social network perspective. Journal of Engineering and Technology Management, 20(1):69–92.Levitt, R.E., Jin, Y. & Dym, C.L. (1991). Knowledge-based support for management of concurrent, multidisciplinary design. Artificial Intelligence for Engineering, Design, Analysis and Manufacturing, 5(2):77–95.Li, C., McMahon, C. & Newnes, L. (2009). Annotation in product lifecycle management: a review of approaches. Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, DETC2009. Vol. 2. New York: ASME, 797–806.Li, W.D., Lu, W.F., Fuh, J.Y. & Wong, Y.S. (2005). Collaborative computer-aided design-research and development status. Computer-Aided Design, 37(9):931–940.Londono, F., Cleetus, K.J., Nichols, D.M., Iyer, S., Karandikar, H.M., Reddy, S.M., Potnis, S.M., Massey, B., Reddy, A. & Ganti, V. (1992). Coordinating a virtual team. CERC-TR-RN-92-005, Concurrent Engineering Research Centre, West Virginia University, West Virginia.Lubell, J., Chen, K., Horst, J., Frechette, S., & Huang, P. (2012). Model based enterprise/technical data package summit report. NIST Technical Note, 1753.May, A. & Carter, C. (2001). A case study of virtual team working in the European automotive industry. International Journal of Industrial Ergonomics, 27(3):171–186.Olson, J.S., Olson, G.M. & Meader, D.K. (1995). What mix of video and audio is useful for small groups doing remote real-time design work? Proceedings of the SIGCHI Conference on Human Factors in Computing Systems. ACM Press, Addison-Wesley Publishing Co.Ping-Hung, H., Mishra, C.S. & Gobeli, D.H. (2003). The return on R&D versus capital expenditures in pharmaceutical and chemical industries. IEEE Transactions on Engineering Management, 50:141–150.Sharma, A. (2005). Collaborative product innovation: integrating elements of CPI via PLM framework. Computer-Aided Design, 37(13):1425–1434.Shum, S.J.B., Selvin, A.M., Sierhuis, M., Conklin, J., Haley, C.B. & Nuseibeh, B. (2006). Hypermedia support for argumentation-based rationale: 15 Years on from Gibis and Qoc. Rationale Management in Software Engineering, 111–132.Siltanen, P. & Valli, S. (2013). Web-based 3D Mediated Communication in Manufacturing Industry. Concurrent Engineering Approaches for Sustainable Product Development in a Multidisciplinary Environment, 1181–1192. Springer London.Stark, J. (2011). Product Lifecycle Management. 1–16. Springer London.Tavcar, J., Potocnik, U. & Duhovnik, J. (2013). PLM used as a backbone for concurrent engineering in supply chain. Concurrent Engineering Approaches for Sustainable Product Development in a Multi-Disciplinary Environment, 681–692.Tay, F.E.H. & Ming, C. (2001). A shared multi-media design environment for concurrent engineering over the internet. Concurrent Engineering, 9(1):55–63.Tay, F.E.H. & Roy, A. (2003). CyberCAD: a collaborative approach in 3D-CAD technology in a multimedia-supported environment. Computers in Industry, 52(2):127–145.Toussaint, J. & Cheng, K. (2002). Design agility and manufacturing responsiveness on the web. Integrated Manufacturing Systems, 13(5):328–339.Tsoi, K.N. & Rahman, S.M. (1996). Media-on-demand multimedia electronic mail: a tool for collaboration on the web. Proceedings of the 5th IEEE International Symposium on High Performance Distributed Computing.Upton, D.M. & Mcafee, A. (1999). The Real Virtual Factory. Harvard Business School Press, 69–89.Vila, C., Estruch, A., Siller, H.R., Abellán, J.V. & Romero, F. (2007). Workflow methodology for collaborative design and manufacturing. Cooperative Design, Visualization, and Engineering 42–49, Springer Berlin Heidelberg.Wasiak, J., Hicks, B., Newnes, L., Dong, A., & Burrow, L. (2010). Understanding engineering email: the development of a taxonomy for identifying and classifying engineering work. Research in Engineering Design, 21(1):43–64.Wasko, M.M. & Faraj, S. (2005). Why should I share? Examining social capital and knowledge contribution in electronic networks of practice. MIS Quarterly: Management Information Systems, 29:35–57.Yang, Q.Z., Zhang, Y., Miao, C.Y. & Shen, Z.Q. (2008). Semantic annotation of digital engineering resources for multidisciplinary design collaboration. ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, 617–624. American Society of Mechanical Engineers.You, C.F. & Chao, S.N. (2006). Multilayer architecture in collaborative environment. Concurrent Engineering Research and Applications, 14(4):273–281.Yuan, Y.C., Fulk, J., Monge, P.R. & Contractor, N. (2010). Expertise directory development, shared task interdependence, and strength of communication network ties as multilevel predictors of expertise exchange in transactive memory work groups. Communication Research, 37: 20–47
Enfermidades determinadas pelo princípio radiomimético de Pteridium aquilinum (Polypodiaceae)
Meta-analysis of type 2 Diabetes in African Americans Consortium
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studies (GWAS) in individuals of European ancestry. In order to investigate the genetic architecture of T2D in African Americans, the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium examined 17 GWAS on T2D comprising 8,284 cases and 15,543 controls in African Americans in stage 1 analysis. Single nucleotide polymorphisms (SNPs) association analysis was conducted in each study under the additive model after adjustment for age, sex, study site, and principal components. Meta-analysis of approximately 2.6 million genotyped and imputed SNPs in all studies was conducted using an inverse variance-weighted fixed effect model. Replications were performed to follow up 21 loci in up to 6,061 cases and 5,483 controls in African Americans, and 8,130 cases and 38,987 controls of European ancestry. We identified three known loci (TCF7L2, HMGA2 and KCNQ1) and two novel loci (HLA-B and INS-IGF2) at genome-wide significance (4.15 × 10(-94)<P<5 × 10(-8), odds ratio (OR) = 1.09 to 1.36). Fine-mapping revealed that 88 of 158 previously identified T2D or glucose homeostasis loci demonstrated nominal to highly significant association (2.2 × 10(-23) < locus-wide P<0.05). These novel and previously identified loci yielded a sibling relative risk of 1.19, explaining 17.5% of the phenotypic variance of T2D on the liability scale in African Americans. Overall, this study identified two novel susceptibility loci for T2D in African Americans. A substantial number of previously reported loci are transferable to African Americans after accounting for linkage disequilibrium, enabling fine mapping of causal variants in trans-ethnic meta-analysis studies.Peer reviewe
Recommended from our members
Track A Basic Science
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138319/1/jia218438.pd
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Reflux Esophagitis as a Possible Risk Factor in the Development of Pharyngolaryngeal Squamous Cell Carcinoma
Metabolizable Energy Values of Soybean Oil Meal and Meat Meal as Affected by Protein Level and Type
- …