Response of Growing Pigs to Diet Physical Form and Allzyme® SSF Supplementation in a Palm Kernel Meal-Based Diet

. The increasing cost of conventional feeds calls for the unconventional ones. The effect of Allzyme®SSF and diet physical form on performance, haematological and serum biochemical indices of growing pigs fed with palm kernel meal-based diet was determined. Twenty four growing pigs comprising of twelve male and twelve female weighing 8.95±1.01Kg were assigned into four dietary treatment groups involving dry mash diet, wet mash diet, dry mash diet+ Allzyme®SSF and wet mash diet+ Allzyme®SSF in a completely randomized design. After feeding experiment for six weeks, haematological and serum biochemical parameters were determined. Growth performance was observed on a weekly basis for six consecutive weeks. The results showed that the diet physical form and Allzyme®SSF supplementation in a palm kernel meal-based diet did not significantly affect the haematological and serum biochemical parameters; however weight gain and feed conversion ratio were significantly influenced by the diet physical form and Allzyme®SSF supplementation, thus making dry mash diet + Allzyme®SSF the best dietary treatment. The experiment showed that the diet physical form and Allzyme®SSF supplementation in a palm kernel meal-based diet did not have any negative effect on the growing pigs and growth performance was not hindered; therefore palm kernel meal-based diet in wet or dry mash form with or without Allzyme® SSF supplementation could be fed to growing pigs

Inequitable childhood immunization uptake in Nigeria: a multilevel analysis of individual and contextual determinants

Background: Immunization coverage in many parts of Nigeria is far from optimal, and far from equitable. Nigeria accounts for half of the deaths from Measles in Africa, the highest prevalence of circulating wild poliovirus in the world, and the country is among the ten countries in the world with vaccine coverage below 50 percent. Studies focusing on community-level determinants therefore have serious policy implications Methods: Multilevel multivariable regression analysis was used on a nationally-representative sample of women aged 15-49 years from the 2003 Nigeria Demographic and Health Survey. Multilevel regression analysis was performed with children (level 1) nested within mothers (level 2), who were in turn nested within communities (level 3). Results: Results show that the pattern of full immunization clusters within families and communities, and that socio-economic characteristics are important in explaining the differentials in full immunization among the children in the study. At the individual level, ethnicity, mothers' occupation, and mothers' household wealth were characteristics of the mothers associated with full immunization of the children. At the community level, the proportion of mothers that had hospital delivery was a determinant of full immunization status. Conclusion: Significant community-level variation remaining after having controlled for child- and mother-level characteristics is indicative of a need for further research on community-levels factors, which would enable extensive tailoring of community-level interventions aimed at improving full immunization and other child health outcomes

Preparation and use of plant medicines for farmers' health in Southwest Nigeria: socio-cultural, magico-religious and economic aspects

Agrarian rural dwellers in Nigeria produce about 95% of locally grown food commodities. The low accessibility to and affordability of orthodox medicine by rural dwellers and their need to keep healthy to be economically productive, have led to their dependence on traditional medicine. This paper posits an increasing acceptance of traditional medicine country-wide and advanced reasons for this trend. The fact that traditional medicine practitioners' concept of disease is on a wider plane vis-à-vis orthodox medicine practitioners' has culminated in some socio-cultural and magico-religious practices observed in preparation and use of plant medicines for farmers' health management. Possible scientific reasons were advanced for some of these practices to show the nexus between traditional medicine and orthodox medicine. The paper concludes that the psychological aspect of traditional medicine are reflected in its socio-cultural and magico-religious practices and suggests that government should fund research into traditional medicine to identify components of it that can be integrated into the national health system

Acceptability of community-based adherence clubs among health facility staff in South Africa: a qualitative study

Ndumiso Tshuma,1,2 Ofentse Mosikare,1,2 Jessica A Yun,1 Olufunke A Alaba,3 Meera S Maheedhariah,4 Keith Muloongo,1,2 Peter S Nyasulu2,5,61Community AIDS Response, Johannesburg, South Africa; 2School of Health Sciences, Monash University South Africa, Johannesburg, South Africa; 3School of Public Health and Family Medicine, University of Cape Town, South Africa; 4Department of Human Behaviour, College of South Nevada and University of California, Los Angeles, CA, USA; 5School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; 6Department of Global Health, Division of Epidemiology and Biostatistics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South AfricaBackground: Patient retention in care for HIV/AIDS is a critical challenge for antiretroviral treatment programs. Community-based adherence programs (CBAPs) as compared to health care facility-based adherence programs have been considered as one of the options to provide treatment maintenance support for groups of patients on antiretroviral therapy. Such an approach provides a way of enhancing self-management of the patient’s condition. In addition, CBAPs have been implemented to support antiretroviral treatment expansion in resource-limited settings. CBAPs involve 30 patients that are allocated to a group and meet at either a facility or a community venue for less than an hour every 2 or 3 months depending on the supply of medication. Our study aimed to establish perceived challenges in moving adherence clubs from health facilities to communities.Methods: A qualitative study was conducted in 39 clinics in Mpumalanga and Gauteng Provinces in South Africa between December 2015 and January 2016. Purposive sampling methods was used to identify nurses, club managers, data capturers, pharmacists and pharmacy assistants who had been involved in facility-based treatment adherence clubs. Key-informant interviews were conducted. Also, semi-structured interviews were used and thematic content analysis was done.Results: A total of 53 health care workers, 12 (22.6%) males and 41 (77.4%) females, participated in the study. Most of them 49 (92.5%) indicated that participating in community adherence clubs were a good idea. Reduction in waiting time at the health facilities, in defaulter rate, improvement in adherence to treatment as well as reduction in stigma were some of the perceived benefits. However, security of medication, storage conditions and transportation of the prepacked medication to the distribution sites were the areas of concern.Conclusion: Health care workers were agreeable to idea of the moving adherence clubs from health facilities to communities. Although some challenges were identified, these could be addressed by the key stakeholders. However, government and nongovernmental organizations need to exercise caution when transitioning to community-based adherence clubs.Keywords: adherence clubs, antiretroviral therapy, HIV, health facility, chronic clubs, cohorts, patient retentio

The mediating role of self-efficacy in the relationship between premotivational cognitions and engagement in multiple health behaviors: a theory-based cross-sectional study among township residents in South Africa

Ndumiso Tshuma,1,2 Keith Muloongo,1,2 Emile S Nkwei,3 Olufunke A Alaba,4 Maheedhariah S Meera,5,6 Maboe G Mokgobi,2 Peter S Nyasulu2,7 1Community AIDS Response, Norwood, Johannesburg, 2School of Health Sciences, Monash South Africa, Johannesburg, 3Osmoz Consulting, Johannesburg, 4School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa; 5Department of Human Behaviour, College of Southern Nevada, Henderson, NV, 6University of California, Los Angeles, Los Angeles, CA, USA; 7School of Public Health, University of the Witwatersrand, Johannesburg, South Africa Background: Noncommunicable diseases (NCDs) are one of the major global health challenges in developed countries and are rapidly increasing globally. Perception of self-efficacy is important for complex activities and long-term changes in health behavior. This study aimed to determine whether self-efficacy mediates the effect of individual beliefs (perceived severity, susceptibility, benefits and barriers) among informal settlement residents’ health behavior in relation to the prevention and management of NCDs. Methods: A cross-sectional survey was conducted using a closed-ended questionnaire among informal settlement residents in Diepsloot, Johannesburg. The proposed model was tested using structural equation modeling (AMOS software). Results: A total of 2,277 participants were interviewed during this survey, consisting of 1,236 (54.3%) females, with the majority of them aged between 20 and 29 years. All constructs in the questionnaire had a good reliability with a Cronbach’s alpha of >0.7. Perceived benefits and perceived barriers were the strongest predictors of self-efficacy, with the highest beta values of 0.14 and 0.15, respectively. Once associated with perceived self-efficacy, the direct effect of perceived susceptibility and perceived benefits on health behavior was statistically nonsignificant (P=0.0894 and P=0.2839, respectively). Perceived benefits and perceived susceptibility were totally mediated by self-efficacy. The indirect effects of perceived severity and perceived barriers (through self-efficacy) on health behavior were significant. Thus, perceived severity and perceived barriers were partially mediated by self-efficacy. Conclusion: Perceived susceptibility and perceived benefits did not affect health behavior unless associated with self-efficacy. In contrast, individual perception of the seriousness of NCDs and perceived barriers might still have a direct influence on health behavior even if the person does not feel able to prevent NCDs. However, this influence would be more significant when perceived severity and perceived barriers of NCDs are associated with self-efficacy. Keywords: perceptions, Diepsloot township, health belief model, noncommunicable diseases, perceived susceptibility, perceived barrier

The path towards herd immunity: Predicting COVID-19 vaccination uptake through results from a stated choice study across six continents

Despite unprecedented progress in developing COVID-19 vaccines, global vaccination levels needed to reach herd immunity remain a distant target, while new variants keep emerging. Obtaining near universal vaccine uptake relies on understanding and addressing vaccine resistance. Simple questions about vaccine acceptance however ignore that the vaccines being offered vary across countries and even population subgroups, and differ in terms of efficacy and side effects. By using advanced discrete choice models estimated on stated choice data collected in 18 countries/territories across six continents, we show a substantial influence of vaccine characteristics. Uptake increases if more efficacious vaccines (95% vs 60%) are offered (mean across study areas = 3.9%, range of 0.6%–8.1%) or if vaccines offer at least 12 months of protection (mean across study areas = 2.4%, range of 0.2%–5.8%), while an increase in severe side effects (from 0.001% to 0.01%) leads to reduced uptake (mean = −1.3%, range of −0.2% to −3.9%). Additionally, a large share of individuals (mean = 55.2%, range of 28%–75.8%) would delay vaccination by 3 months to obtain a more efficacious (95% vs 60%) vaccine, where this increases further if the low efficacy vaccine has a higher risk (0.01% instead of 0.001%) of severe side effects (mean = 65.9%, range of 41.4%–86.5%). Our work highlights that careful consideration of which vaccines to offer can be beneficial. In support of this, we provide an interactive tool to predict uptake in a country as a function of the vaccines being deployed, and also depending on the levels of infectiousness and severity of circulating variants of COVID-19