382 research outputs found
Social and professional contradictions as components of psychological safety of experts of public catering
In article problems of psychological safety of experts of public catering, a complex of contradictions, degree of expressiveness and completeness of manifestations of social and professional components of psychological safety are consideredВ статье рассматриваются проблемы психологической безопасности специалистов общественного питания, комплекс противоречий, степень выраженности и полнота проявлений социальных и профессиональных компонентов психологической безопасност
Scarring Effects on Tunneling in Chaotic Double-Well Potentials
The connection between scarring and tunneling in chaotic double-well
potentials is studied in detail through the distribution of level splittings.
The mean level splitting is found to have oscillations as a function of energy,
as expected if scarring plays a role in determining the size of the splittings,
and the spacing between peaks is observed to be periodic of period
{} in action. Moreover, the size of the oscillations is directly
correlated with the strength of scarring. These results are interpreted within
the theoretical framework of Creagh and Whelan. The semiclassical limit and
finite-{} effects are discussed, and connections are made with reaction
rates and resonance widths in metastable wells.Comment: 22 pages, including 11 figure
SOME ABSTRACT PROPERTIES OF SEMIGROUPS APPEARING IN SUPERCONFORMAL THEORIES
A new type of semigroups which appears while dealing with
superconformal symmetry in superstring theories is considered. The ideal series
having unusual abstract properties is constructed. Various idealisers are
introduced and studied. The ideal quasicharacter is defined. Green's relations
are found and their connection with the ideal quasicharacter is established.Comment: 11 page
Quantification of uncertainties in global grazing systems assessments
Livestock systems play a key role in global sustainability challenges like food security and climate change, yet, many unknowns and large uncertainties prevail. We present a systematic, spatially explicit assessment of uncertainties related to grazing intensity (GI), a key metric for assessing ecological impacts of grazing, by combining existing datasets on a) grazing feed intake, b) the spatial distribution of livestock, c) the extent of grazing land, and d) its net primary productivity (NPP). An analysis of the resulting 96 maps implies that on average 15% of the grazing land NPP is consumed by livestock. GI is low in most of worlds grazing lands but hotspots of very high GI prevail in 1% of the total grazing area. The agreement between GI maps is good on one fifth of the world's grazing area, while on the remainder it is low to very low. Largest uncertainties are found in global drylands and where grazing land bears trees (e.g., the Amazon basin or the Taiga belt). In some regions like India or Western Europe massive uncertainties even result in GI > 100% estimates. Our sensitivity analysis indicates that the input-data for NPP, animal distribution and grazing area contribute about equally to the total variability in GI maps, while grazing feed intake is a less critical variable. We argue that a general improvement in quality of the available global level datasets is a precondition for improving the understanding of the role of livestock systems in the context of global environmental change or food security
The potential utility of B cell-directed biologic therapy in autoimmune diseases
Increasing awareness of the importance of aberrant B cell regulation in autoimmunity has driven the clinical development of novel B cell-directed biologic therapies with the potential to treat a range of autoimmune disorders. The first of these drugs—rituximab, a chimeric monoclonal antibody against the B cell-specific surface marker CD20—was recently approved for treating rheumatoid arthritis in patients with an inadequate response to other biologic therapies. The aim of this review is to discuss the potential use of rituximab in the management of other autoimmune disorders. Results from early phase clinical trials indicate that rituximab may provide clinical benefit in systemic lupus erythematosus, Sjögren’s syndrome, vasculitis, and thrombocytopenic purpura. Numerous case reports and several small pilot studies have also been published reporting the use of rituximab in conditions such as myositis, antiphospholipid syndrome, Still’s disease, and multiple sclerosis. In general, the results from these preliminary studies encourage further testing of rituximab therapy in formalized clinical trials. Based on results published to date, it is concluded that rituximab, together with other B cell-directed therapies currently under clinical development, is likely to provide an important new treatment option for a number of these difficult-to-treat autoimmune disorders
Importance of non-CO2 emissions in carbon management
Background: GHG budgets highlight a need for urgency, yet analyses are often CO2-focused, with less attention paid to non-CO2. Results: In this paper, scenarios are used to explore non-CO2 drivers and barriers to their mitigation, drawing out implications for CO2 management. Results suggest that even optimistic technological and consumption-related developments lead to on-going increases in global N2O, largely to improve food security within a changing climate. This contrasts with existing analysis, where lower levels of N2O by 2050 are projected. Conclusions: As avoiding '2°C' limits the emissions budget, constraints on reducing non-CO2 add pressure to energy system decarbonization. Overlooking how a changing climate and rising consumption restricts efforts to curb non-CO2 will result in policies aiming to avoid 2°C falling short of the mark
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