310 research outputs found

    AÇÕES PREVENTIVAS CONTRA O USO DE ÁLCOOL E DROGAS: RELATO DE EXPERIÊNCIA

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    Este estudo se trata de um relato de experiência de alunos bolsistas de um projeto de extensão do Departamento de Saúde da Universidade Estadual do Sudoeste da Bahia (UESB), que executa ações de prevenção contra o uso de álcool e drogas. O trabalho justifica-se pelo aumento do número de usuários de drogas, o que repercute negativamente no contexto social do município de Jequié, na Bahia. As ações são desenvolvidas por meio de palestras, reuniões, oficinas com grupos escolares e religiosos, feiras de saúde e grupos de comunidades, a fim de diminuir as estatísticas sobre os usuários de drogas nessa cidade. Essas atividades mostram a importância de prevenir o primeiro contato com substâncias tóxicas, no intuito de favorecer a qualidade de vida e a saúde mental da população, com métodos mais saudáveis. Com essas atividades de extensão, foi possível perceber a importância do esclarecimento sobre as consequências negativas do uso de álcool e substâncias ilícitas no organismo do indivíduo e no contexto intrafamiliar e social

    AÇÕES PREVENTIVAS CONTRA O USO DE ÁLCOOL E DROGAS: RELATO DE EXPERIÊNCIA

    Get PDF
    Este estudo se trata de um relato de experiência de alunos bolsistas de um projeto de extensão do Departamento de Saúde da Universidade Estadual do Sudoeste da Bahia (UESB), que executa ações de prevenção contra o uso de álcool e drogas. O trabalho justifica-se pelo aumento do número de usuários de drogas, o que repercute negativamente no contexto social do município de Jequié, na Bahia. As ações são desenvolvidas por meio de palestras, reuniões, oficinas com grupos escolares e religiosos, feiras de saúde e grupos de comunidades, a fim de diminuir as estatísticas sobre os usuários de drogas nessa cidade. Essas atividades mostram a importância de prevenir o primeiro contato com substâncias tóxicas, no intuito de favorecer a qualidade de vida e a saúde mental da população, com métodos mais saudáveis. Com essas atividades de extensão, foi possível perceber a importância do esclarecimento sobre as consequências negativas do uso de álcool e substâncias ilícitas no organismo do indivíduo e no contexto intrafamiliar e social

    Improving physical activity behaviors, physical fitness, cardiometabolic and mental health in adolescents - ActTeens program : a protocol for a randomized controlled trial

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    This trial aims to investigate the effects of the ActTeens physical activity program, on adolescents' physical activity level, health-related fitness, cardiometabolic and mental health. The trial will aim to recruit ∼140 adolescents (aged 13-14 years). Participants will be randomized into either intervention or control groups. The intervention will be guided by social cognitive theory and self-determination theory and implemented over one school term (24- weeks). The ActTeens Program will include: (1) structured physical activity sessions delivered within physical education, including movement-based games and dynamic stretching warm-ups; resistance training skill development; high-intensity training workouts; and cooldowns; (2) self-monitoring plus goal setting for physical activity by pedometer-smart wearable; and (3) healthy lifestyle guidance (social support) by WhatsApp® messages about healthy eating and regular physical activity for the intervention and parents groups. Study outcomes will be assessed at baseline, 24-weeks from baseline, and 12-months from baseline. Physical activity (accelerometer) is the primary outcome. Secondary outcomes include muscular and cardiorespiratory fitness, cardiometabolic profile, and mental health. A process evaluation will be conducted (i.e., recruitment, retention, attendance, and program satisfaction). This project will have the potential to address many questions and debates regarding the implementation of physical activity interventions in low-and- middle-income countries

    Leaf heteroblasty in Passiflora edulis as revealed by metabolic profiling and expression analyses of the microRNAs miR156 and miR172

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    Juvenile-to-adult phase transition is marked by changes in leaf morphology, mostly due to the temporal development of the shoot apical meristem, a phenomenon known as heteroblasty. Sugars and microRNA-controlled modules are components of the heteroblastic process in Arabidopsis thaliana leaves. However, our understanding about their roles during phase-changing in other species, such as Passiflora edulis, remains limited. Unlike Arabidopsis, P. edulis (a semi-woody perennial climbing vine) undergoes remarkable changes in leaf morphology throughout juvenile-to-adult transition. Nonetheless, the underlying molecular mechanisms are unknown.Here we evaluated the molecular mechanisms underlying the heteroblastic process by analysing the temporal expression of microRNAs and targets in leaves as well as the leaf metabolome during P. edulis development.Metabolic profiling revealed a unique composition of metabolites associated with leaf heteroblasty. Increasing levels of glucose and α-trehalose were observed during juvenile-to-adult phase transition. Accumulation of microRNA156 (miR156) correlated with juvenile leaf traits, whilst miR172 transcript accumulation was associated with leaf adult traits. Importantly, glucose may mediate adult leaf characteristics during de novo shoot organogenesis by modulating miR156-targeted PeSPL9 expression levels at early stages of shoot development.Altogether, our results suggest that specific sugars may act as co-regulators, along with two microRNAs, leading to leaf morphological modifications throughout juvenile-to-adult phase transition in P. edulis
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