Carcinoma of the Eye.

October 25, 1948, a 10-year-old white stock-horse was admitted to Stange Memorial Clinic. Prior to its entry the horse had been treated for a carcinoma by surgical removal of the left lower eye lid

Cervical Deformity Patients Have Baseline Swallowing Dysfunction but Surgery Does Not Increase Dysphagia at 3 Months: Results From a Prospective Cohort Study.

Study designProspective cohort study.ObjectivesMost studies of dysphagia in the cervical spine have focused on a degenerative patient population; the rate of dysphagia following surgery for cervical deformity (CD) is unknown. This study aims to investigate if surgery for cervical deformity results in postoperative dysphagia.MethodsPatients with CD undergoing surgery from 2013 to 2015 were prospectively enrolled to evaluate dysphagia. Demographic, operative, and radiographic variables were analyzed. The Quality of Life in Swallowing Disorders (SWAL-QoL) was used to measure dysphagia. Paired t test, independent t tests, and bivariate Pearson correlations were performed.ResultsA total of 88 CD patients, aged 61.52 ± 10.52 years, were enrolled. All patients (100%) had 3-month SWAL-QoL for analysis. The baseline preoperative SWAL-QoL was 78.35. This is roughly the same level of dysphagia as an anterior cervical discectomy patient that is 3 weeks removed from surgery. Increasing body mass index (BMI) was correlated with decreased SWAL-QoL score (r = -0.30, P = .001). Age, gender, smoking, and Charlson Comorbidity Index (CCI) showed no significant correlations with preoperative SWAL-QoL. Patients with prior cervical surgery had a lower preoperative SWAL-QoL (P = .04). While 11 patients had acute postoperative dysphagia, CD surgery did not result in lower SWAL-QoL at 3 months (77.26 vs 78.35, P = .53). Surgical variables, including estimated blood loss (EBL), anterior or posterior fusion levels, steroid use, preoperative traction, staged surgery, surgical approach, anterior corpectomy, posterior osteotomy, and UIV (upper instrumented vertebrae) location, showed no impact on postoperative SWAL-QoL. Correction of cervical kyphosis was not correlated to 3-month SWAL-QoL scores or the change in SWAL-QoL scores.ConclusionsWhile patients undergoing surgery for cervical deformity had swallowing dysfunction at baseline, we did not observe a significant decline in SWAL-QoL scores at 3 months. Patients with prior cervical surgery and higher BMI had a lower baseline SWAL-QoL. There were no surgical or radiographic variables correlated to a change in SWAL-QOL score

Latent print comparison and examiner conclusions: A field analysis of case processing in one crime laboratory

Scholarship on the latent print comparison process has expanded in recent years, responsive to the call for rigorous research by scholarly groups (e.g., National Academy of Sciences, 2009; President’s Council of Advisors on Science and Technology, 2016). Important to the task of ultimately improving accuracy, consistency, and efficiency in the field is understanding different workflows and case outcomes. The current study describes the casework completed by a latent print unit in a large laboratory during one calendar year (2018), including a unique workflow that involves Preliminary AFIS Associations reported out as investigative leads. Approximately 45% of all examined prints were deemed to be of sufficient quality to enter into AFIS, and 22% of AFIS entries resulted in potential identifications. But examiner conclusions and AFIS outcomes (across three AFIS databases) varied according to case details, print source, and AFIS database. Moreover, examiners differed in case processing, sufficiency determinations, and AFIS conclusions. Results are discussed with respect to implications for future research (e.g., comparing these data to case processing data for other laboratories) and ultimately improving the practice of latent print examination

The posterior use of BMP-2 in cervical deformity surgery does not result in increased early complications: A prospective multicenter study

Study designProspective cohort study.ObjectivesTo describe the rate of short-term complications following the posterior use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in cervical deformity (CD) surgery.MethodsCD patients from 2013 to 2015 were enrolled in a prospective, multicenter database. Patients were divided into those receiving rhBMP-2 (BMP) and no rhBMP-2 (NOBMP). The relationship between BMP use, demographic variables surgical variables, radiographic parameters and complications was evaluated.ResultsA total of 100 patients (47 BMP, 53 NOBMP) were included. Follow-up time averaged 7.6 months (range 3-12 months). An average of 13.6mg of BMP was used per person with 1.49 mg per level. Compared with the NOBMP group, patients in the BMP group were older (P = .03). BMP was more commonly used in patients that and had longer prior fusions (6.0 vs 2.5, P < .01). There were no differences between groups with regards to a history of surgery, Charlson Comorbidity Index, estimated blood loss, operation time, fusion levels, and surgical approach. The maintenance of radiographic parameters at 6-month follow-up was similar. There were no differences in terms of total complication incidence, total complications per person, major complications per person or any specific complication. Linear regression and Pearson correlation analysis did not reveal any strong r2 values (r2 = 0.09, 0.08, 0.06) between the use of BMP and complications (major or operative).ConclusionsBMP use was not directly associated with an increased incidence of early complications in this prospective cohort of operative adult CD patients. Its use was associated with increased number of levels instrumented and fused

Characterizing groundwater flow and heat transport in fractured rock using Fiber-Optic Distributed Temperature Sensing

International audienceWe show how fully distributed space-time measurements with Fiber-Optic Distributed Temperature Sensing (FO-DTS) can be used to investigate groundwater flow and heat transport in fractured media. Heat injection experiments are combined with temperature measurements along fiber-optic cables installed in boreholes. Thermal dilution tests are shown to enable detection of cross-flowing fractures and quantification of the cross flow rate. A cross borehole thermal tracer test is then analyzed to identify fracture zones that are in hydraulic connection between boreholes and to estimate spatially distributed temperature breakthrough in each fracture zone. This provides a significant improvement compared to classical tracer tests, for which concentration data are usually integrated over the whole abstraction borehole. However, despite providing some complementary results, we find that the main contributive fracture for heat transport is different to that for a solute tracer

Onset Transition to Cold Nuclear Matter from Lattice QCD with Heavy Quarks

Lattice QCD at finite density suffers from a severe sign problem, which has so far prohibited simulations of the cold and dense regime. Here we study the onset of nuclear matter employing a three-dimensional effective theory derived by combined strong coupling and hopping expansions, which is valid for heavy but dynamical quarks and has a mild sign problem only. Its numerical evaluations agree between a standard Metropolis and complex Langevin algorithm, where the latter is free of the sign problem. Our continuum extrapolated data clearly show a first order phase transition building up at $\mu_B \approx m_B$ as the temperature approaches zero. An excellent description of the data is achieved by an analytic solution in the strong coupling limit.Comment: Four pages, three figures; uses REVTeX-4. Version accepted by PRL. Title changed upon request by the Editor

Onset Transition to Cold Nuclear Matter from Lattice QCD with Heavy Quarks

Lattice QCD at finite density suffers from a severe sign problem, which has so far prohibited simulations of the cold and dense regime. Here we study the onset of nuclear matter employing a three-dimensional effective theory derived by combined strong coupling and hopping expansions, which is valid for heavy but dynamical quarks and has a mild sign problem only. Its numerical evaluations agree between a standard Metropolis and complex Langevin algorithm, where the latter is free of the sign problem. Our continuum extrapolated data approach a first order phase transition at µB ≈ mB as the temperature approaches zero. An excellent description of the data is achieved by an analytic solution in the strong coupling limit. PACS numbers: 05.70. Fh,11.15Ha,12.38.Gc Keywords: QCD phase diagram, lattice gauge theory, sign problem QCD at zero temperature is expected to exhibit the so-called silver blaze property: when a chemical potential for baryon number µ B is switched on in the grand canonical partition function, initially all observables should be completely independent of µ B . This changes abruptly once the chemical potential exceeds a critical value µ Bc , for which the baryon number jumps from zero to a finite value and a transition to a condensed state of nuclear matter takes place. The reason for this behavior is the mass gap in the fermionic spectrum, where the nucleon mass m B represents the lowest baryonic energy that can be populated once µ B ≈ m B . While this picture is easy to see in terms of energy levels of nucleons in a Hamiltonian language, it is elusive in the fundamental formulation of QCD thermodynamics in terms of a path integral. There, chemical potential enters through the Dirac operators of the quark fields, and hence all Dirac eigenvalues are shifted for any value of µ B . The silver blaze property thus requires some exact cancellations for µ B < m B . An analytic derivation of the silver blaze property from the path integral exists only for the related case of finite isospin chemical potential where Bose-Einstein condensation of pions sets in at µ I = m π /2. A numerical demonstration of the effect by means of lattice QCD has so far been impossible due to the so-called sign problem. For finite baryon chemical potential the action becomes complex, prohibiting its use in a Boltzmann factor for Monte Carlo approaches with importance sampling. Several approximate methods have been devised to circumvent this problem. These are valid in the regime µ < ∼ T , where they give consistent results (for a recent review see In this work we show that cold and dense lattice QCD is accessible within a 3d effective theory of Polyakov loops, which has been derived from the full lattice theory with Wilson fermions by means of strong coupling and hopping parameter expansions The lattice QCD partition function with Wilson gauge action S g [U ] and f = 1, . . . , N f quark flavours with Wilson fermion matrix Q(κ f , µ f ) can be written a