339 research outputs found

    Low Energy Properties of the Kondo chain in the RKKY regime

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    We study the Kondo chain in the regime of high spin concentration where the low energy physics is dominated by the Ruderman-Kittel-Kasuya-Yosida (RKKY) interaction. As has been recently shown (A. M. Tsvelik and O. M. Yevtushenko, Phys. Rev. Lett 115, 216402 (2015)), this model has two phases with drastically different transport properties depending on the anisotropy of the exchange interaction. In particular, the helical symmetry of the fermions is spontaneously broken when the anisotropy is of the easy plane type (EP). This leads to a parametrical suppression of the localization effects. In the present paper we substantially extend the previous theory, in particular, by analyzing a competition of forward- and backward- scattering, including into the theory short range electron interactions and calculating spin correlation functions. We discuss applicability of our theory and possible experiments which could support the theoretical findings.Comment: 24 pages, 8 figures, 5 appendice

    The tailings dam failure of 5 November 2015 in SE Brazil and its preceding seismic sequence

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    The collapse of a mine tailings dam and subsequent flood in SE Brazil on 5 November 2015 was preceded by a small-magnitude seismic sequence. In this report, we explore the spatiotemporal associations between the seismic events and the accident and discuss their possible connection. We also analyze the signals generated by the turbulent mudflow, as recorded by the Brazilian Seismographic Network (RSBR). In light of our observations, we propose as possible contributing factor for the dam collapse either ground shaking and/or soil liquefaction triggered by the earthquakes. The possibility of such a small-magnitude earthquake contributing to the collapse of a tailings dam raises important concerns regarding safety and related legislation of dams in Brazil and the world. ©2016. American Geophysical Union.H.A.D. and M.A. acknowledge support from Sao Paulo Research Foundation FAPESP grant 2014/09455-3 and CNPq grant 30.6547/2013-9.Peer reviewe

    ‘O sibling, where art thou?’ – a review of avian sibling recognition with respect to the mammalian literature

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    Avian literature on sibling recognition is rare compared to that developed by mammalian researchers. We compare avian and mammalian research on sibling recognition to identify why avian work is rare, how approaches differ and what avian and mammalian researchers can learn from each other. Three factors: (1) biological differences between birds and mammals, (2) conceptual biases and (3) practical constraints, appear to influence our current understanding. Avian research focuses on colonial species because sibling recognition is considered adaptive where ‘mixing potential’ of dependent young is high; research on a wider range of species, breeding systems and ecological conditions is now needed. Studies of acoustic recognition cues dominate avian literature; other types of cues (e.g. visual, olfactory) deserve further attention. The effect of gender on avian sibling recognition has yet to be investigated; mammalian work shows that gender can have important influences. Most importantly, many researchers assume that birds recognise siblings through ‘direct familiarisation’ (commonly known as associative learning or familiarity); future experiments should also incorporate tests for ‘indirect familiarisation’ (commonly known as phenotype matching). If direct familiarisation proves crucial, avian research should investigate how periods of separation influence sibling discrimination. Mammalian researchers typically interpret sibling recognition in broad functional terms (nepotism, optimal outbreeding); some avian researchers more successfully identify specific and testable adaptive explanations, with greater relevance to natural contexts. We end by reporting exciting discoveries from recent studies of avian sibling recognition that inspire further interest in this topic

    Sulfide melts and long-term low seismic wavespeeds in lithospheric and asthenospheric mantle

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    Some studies of lithospheric and asthenospheric seismic structure, report mantle velocities as low as ∼4% below the reference models used. While these low wavespeeds may be attributed to thermal effects in tectonically young or actively volcanic regions, in older, tectonically stable regions low velocity anomalies apparently persist even past the decay time of any thermal perturbation, rendering such a mechanism implausible. Low volume melts can also reduce wavespeeds, but their buoyancy should drain them upward away from source regions, preventing significant accumulation if they are able to segregate. Sulfide, ubiquitous as inclusions in lithospheric mantle xenoliths, forms dense, non-segregating melts at temperatures and volatile fugacities characteristic of even old lithospheric mantle. We show that 1–5 volume percent sulfide melts can act to permanently create reductions up to 5.5% in seismic wavespeeds in areas of the lithosphere and the asthenosphere disturbed by prior melting events that carry and concentrate sulfide

    RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2α

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    Hypoxia-inducible factors (HIFs) are critical transcription factors that mediate cell survival during reduced oxygen conditions (hypoxia). At regular oxygen conditions (normoxia), HIF-1α and HIF-2α are continuously synthesized in cells and degraded via the ubiquitin–proteasome pathway. During hypoxia, these proteins are stabilized and translocate to the nucleus to activate transcription of target genes that enable cell survival at reduced oxygen levels. HIF proteins are tightly regulated via post-translational modifications including phosphorylation, acetylation, prolyl-hydroxylation and ubiquitination. Here we show for the first time that exogenous and endogenous HIF-2α are also regulated via the ubiquitin-like modifier small ubiquitin-like modifiers (SUMO). Using mutational analysis, we found that K394, which is situated in the sumoylation consensus site LKEE, is the major SUMO acceptor site in HIF-2α. Functionally, sumoylation reduced the transcriptional activity of HIF-2α. Similar to HIF-1α, HIF-2α is regulated by the SUMO protease SENP1. The proteasome inhibitor MG132 strongly stabilized SUMO-2-conjugated HIF-2α during hypoxia but did not affect the total level of HIF-2α. The ubiquitin E3 ligases von Hippel–Lindau and RNF4 control the levels of sumoylated HIF-2α, indicating that sumoylated HIF-2α is degraded via SUMO-targeted ubiquitin ligases

    Biological effects of rinsing morsellised bone grafts before and after impaction

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    Rinsing bone grafts before or both before and after impaction might have different effects on the incorporation of the graft. Rinsing again after impaction might negatively influence bone induction if growth factors released by impaction are washed away. We studied if transforming growth factor-βs (TGF-βs) and bone morphogenetic proteins (BMPs) are released from the mineralised matrix by impaction and if these released growth factors induce osteogenic differentiation in human mesenchymal stem cells (hMSCs). Rinsed morsellised bone allografts were impacted in a cylinder and the escaping fluid was collected. The fluid was analysed for the presence of TGF-βs and BMPs, and the osteoinductive capacity was tested on hMSCs. Abundant TGF-β was present in the fluid. No BMPs could be detected. Osteogenic differentiation of hMSCs was inhibited by the fluid. Results from our study leave us only able to speculate whether rinsing grafts again after impaction has a beneficial effect on the incorporation process or not

    Faunistic Composition, Ecological Properties and Zoogeographical Composition of the Family Elateridae (Coleoptera) of the Central Anatolian Region of Turkey

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    The focus of this study was to understand the faunistic composition, ecological properties and zoogeographical composition of Elateridae (Coleoptera) of the Central Anatolian region. 72 species belonging to seven subfamilies and 25 genera were identified. The major part of the Elateridae fauna of the Central Anatolian region is formed by the subfamilies Elaterinae and Cardiophorinae. The genus Cardiophorus was the most species-rich genus. The species composition of the Elateridae fauna of the Central Anatolian region is partially consistent with known Elateridae fauna of Turkey. The Central Anatolian region shares most species with the European part of the Western Palaearctic as does the Elateridae fauna of Turkey. Detailed localities of nine species are given for the first time for Turkey, with emphasis on the Central Anatolian region

    Effects of stimulus duration on audio-visual synchrony perception

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    The integration of visual and auditory inputs in the human brain occurs only if the components are perceived in temporal proximity, that is, when the intermodal time difference falls within the so-called subjective synchrony range. We used the midpoint of this range to estimate the point of subjective simultaneity (PSS). We measured the PSS for audio-visual (AV) stimuli in a synchrony judgment task, in which subjects had to judge a given AV stimulus using three response categories (audio first, synchronous, video first). The relevant stimulus manipulation was the duration of the auditory and visual components. Results for unimodal auditory and visual stimuli have shown that the perceived onset shifts to relatively later positions with increasing stimulus duration. These unimodal shifts should be reflected in changing PSS values, when AV stimuli with different durations of the auditory and visual components are used. The results for 17 subjects showed indeed a significant shift of the PSS for different duration combinations of the stimulus components. Because the shifts were approximately equal for duration changes in either of the components, no net shift of the PSS was observed as long as the durations of the two components were equal. This result indicates the need to appropriately account for unimodal timing effects when quantifying intermodal synchrony perceptio
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