Landslide mapping and monitoring by using radar and optical remote sensing: examples from the EC-FP7 project SAFER

This paper focuses on the Landslide Thematic services of the EU-funded FP7-SPACE project SAFER (Services and Applications For Emergency Response) for inventory mapping, monitoring and rapid mapping by using Earth Observation (EO). We exploited satellite Interferometric Synthetic Aperture Radar (InSAR) and Object-Based Image Analysis (OBIA), and discuss example applications in South Tyrol and Abruzzo (Italy), Lower Austria (Austria), Lubietova (Slovakia) and the Kaohsiung County (Taiwan). These case studies showcase the significance of radar and optical EO data, InSAR and OBIA methods for landslide mapping and monitoring in different geological environments and during all phases of emergency management: mitigation, preparedness, crisis and recovery

Bronchial Thermoplasty Global Registry (BTGR) : 2-year results

Funding This study was sponsored by Boston Scientific Corporation, Marlborough, MA, USA.Objectives Bronchial thermoplasty (BT) is a device-based treatment for subjects ≥18 years with severe asthma not well controlled with inhaled corticosteroids and long-acting beta-agonists. The Bronchial Thermoplasty Global Registry (BTGR) collected real-world data on subjects undergoing this procedure. Design The BTGR is an all-comer, prospective, open-label, multicentre study enrolling adult subjects indicated for and treated with BT. Setting Eighteen centres in Spain, Italy, Germany, the UK, the Netherlands, the Czech Republic, South Africa and Australia Participants One hundred fifty-seven subjects aged 18 years and older who were scheduled to undergo BT treatment for asthma. Subjects diagnosed with other medical conditions which, in the investigator's opinion, made them inappropriate for BT treatment were excluded. Primary and secondary outcome measures Baseline characteristics collected included demographics, Asthma Quality of Life Questionnaire (AQLQ), Asthma Control Test (ACT), medication usage, forced expiratory volume in one second and forced vital capacity, medical history, comorbidities and 12-month baseline recall data (severe exacerbations (SE) and healthcare utilisation). SE incidence and healthcare utilisation were summarised at 1 and 2 years post-BT. Results Subjects' baseline characteristics were representative of persons with severe asthma. A comparison of the proportion of subjects experiencing events during the 12 months prior to BT to the 2-year follow-up showed a reduction in SE (90.3% vs 56.1%, p<0.0001), emergency room visits (53.8% vs 25.5%, p<0.0001) and hospitalisations (42.9% vs 23.5 %, p=0.0019). Reductions in asthma maintenance medication dosage were also observed. AQLQ and ACT scores improved from 3.26 and 11.18 at baseline to 4.39 and 15.54 at 2 years, respectively (p<0.0001 for both AQLQ and ACT). Conclusions The BTGR demonstrates sustained improvement in clinical outcomes and reduction in asthma medication usage 2 years after BT in a real-world population. This is consistent with results from other BT randomised controlled trials and registries and further supports improvement in asthma control after BT. Trial registration number NCT02104856

Guidelines on the diagnosis, treatment and management of visceral and renal arteries aneurysms: a joint assessment by the Italian Societies of Vascular and Endovascular Surgery (SICVE) and Medical and Interventional Radiology (SIRM)

: The objective of these Guidelines is to provide recommendations for the classification, indication, treatment and management of patients suffering from aneurysmal pathology of the visceral and renal arteries. The methodology applied was the GRADE-SIGN version, and followed the instructions of the AGREE quality of reporting checklist. Clinical questions, structured according to the PICO (Population, Intervention, Comparator, Outcome) model, were formulated, and systematic literature reviews were carried out according to them. Selected articles were evaluated through specific methodological checklists. Considered Judgments were compiled for each clinical question in which the characteristics of the body of available evidence were evaluated in order to establish recommendations. Overall, 79 clinical practice recommendations were proposed. Indications for treatment and therapeutic options were discussed for each arterial district, as well as follow-up and medical management, in both candidate patients for conservative therapy and patients who underwent treatment. The recommendations provided by these guidelines simplify and improve decision-making processes and diagnostic-therapeutic pathways of patients with visceral and renal arteries aneurysms. Their widespread use is recommended

Semi-Automatic Identification and Pre-Screening of Geological–Geotechnical Deformational Processes Using Persistent Scatterer Interferometry Datasets

This work describes a new procedure aimed to semi-automatically identify clusters of active persistent scatterers and preliminarily associate them with different potential types of deformational processes over wide areas. This procedure consists of three main modules: (i) ADAfinder, aimed at the detection of Active Deformation Areas (ADA) using Persistent Scatterer Interferometry (PSI) data; (ii) LOS2HV, focused on the decomposition of Line Of Sight (LOS) displacements from ascending and descending PSI datasets into vertical and east-west components; iii) ADAclassifier, that semi-automatically categorizes each ADA into potential deformational processes using the outputs derived from (i) and (ii), as well as ancillary external information. The proposed procedure enables infrastructures management authorities to identify, classify, monitor and categorize the most critical deformations measured by PSI techniques in order to provide the capacity for implementing prevention and mitigation actions over wide areas against geological threats. Zeri, Campiglia Marittima–Suvereto and Abbadia San Salvatore (Tuscany, central Italy) are used as case studies for illustrating the developed methodology. Three PSI datasets derived from the Sentinel-1 constellation have been used, jointly with the geological map of Italy (scale 1:50,000), the updated Italian landslide and land subsidence maps (scale 1:25,000), a 25 m grid Digital Elevation Model, and a cadastral vector map (scale 1:5000). The application to these cases of the proposed workflow demonstrates its capability to quickly process wide areas in very short times and a high compatibility with Geographical Information System (GIS) environments for data visualization and representation. The derived products are of key interest for infrastructures and land management as well as decision-making at a regional scale.This research was funded by the Shift2Rail Joint Undertaking under the European Union’s Horizon 2020 research and innovation program, with grant agreement No 777630, project MOMIT, “Multiscale Observation and Monitoring of railway Infrastructure Threats” and the Spanish Ministry of Economy, Industry and Competitiveness (MINECO), the State Agency of Research (AEI), and the European Funds for Regional Development (FEDER) under project TEC2017-85244-C2-1-P

Longitudinal Study of the Respiratory Function in Preterm Born Children: Comparison Between Subjects with and without Bronchopulmonary Dysplasia

Abstract The long-term changes of the respiratory function in patients with broncho-pulmonary dysplasia (BPD) are still largely unknown. Aim: To study longitudinally the lung function of patients with BPD approaching the adulthood, compared with preterm born subjects without BPD (non-BPD). Methods: 23 preterm born subjects with a gestational age of 23 ± 3 weeks and birth weight of 1296 ± 543 gr were studied and divided in two groups, one with BPD (n = 13) and one without BDP (n = 10) according to the Shennan definition and then reclassified following the definition NICHHD (n = 16 BPD and n = 7 non-BPD). Pulmonary function testing was performed at age of 9.2 ± 2.2 yr (T1) and 15.2 ± 2.3 yr (T2). The two groups were compared both at T1 and T2 and changes from T1 and T2 were assessed in both groups. Results: The functional parameters of the non-BPD subjects were in the normal range at T1, except FEF25-75% that, however, showed a tendency towards the normality at T2. The BPD patients had mild airflow obstruction, mainly localized in the small airways, with marked air trapping at T1. A significant improvement of lung volumes and maximal expiratory flows was observed at T2. Conclusions: The presence of BPD was associated with an obstructive ventilatory defect at age 9, substantially involving the peripheral airways that still persisted at age 15, although with a lesser degree of severity