545 research outputs found

    Measuring Cerebral and Cerebellar Glutathione in Children Using 1H MEGA-PRESS MRS

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    HST observations of the cometary blue compact dwarf galaxy UGC 4483: a relatively young galaxy?

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    We present V and I photometry of the resolved stars in the cometary blue compact dwarf galaxy UGC 4483 using Hubble Space Telescope Wide Field Planetary Camera 2 (WFPC2) images. The resulting I vs. (V-I) color-magnitude diagram (CMD) reaches limiting magnitudes V = 27.5 mag and I = 26.5 mag for photometric errors less than 0.2 mag. It reveals not only a young stellar population of blue main-sequence stars and blue and red supergiants, but also an older evolved population of red giant and asymptotic giant branch stars. The measured magnitude I = 23.65 +/- 0.10 mag of the red giant branch tip results in a distance modulus (m-M) = 27.63 +/- 0.12, corresponding to a distance of 3.4 +/- 0.2 Mpc. The youngest stars are associated with the bright H II region at the northern tip of the galaxy. The population of older stars is found throughout the low-surface-brightness body of the galaxy and is considerably more spread out than the young stellar population, suggesting stellar diffusion. The most striking characteristics of the CMD of UGC 4483 are the very blue colors of the red giant stars and the high luminosity of the asymptotic giant branch stars. Both of these characteristics are consistent with either: 1) a very low metallicity ([Fe/H] = -2.4 like the most metal-deficient globular clusters) and an old age of 10 Gyr, or 2) a higher metallicity ([Fe/H] = -1.4 as derived from the ionized gas emission lines) and a relatively young age of the oldest stellar population in UGC 4483, not exceeding ~ 2 Gyr. Thus our data do not exclude the possibility that UGC 4483 is a relatively young galaxy having formed its first stars only ~ 2 Gyr ago.Comment: 37 pages, 15 PS figures, to appear in Ap

    The blue compact dwarf galaxy I Zw 18: a comparative study of its low-surface-brightness component

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    (abridged): Using HST and ground-based optical and NIR imaging data, we investigate whether the blue compact dwarf (BCD) galaxy I Zw 18 possesses an extended low-surface-brightness (LSB) old stellar population underlying its star-forming (SF) regions. We show that the exponential intensity decrease observed in the filamentary LSB envelope of the BCD out to 18 arcsec (1.3 kpc at a distance of 15 Mpc) is not due to an evolved stellar disc, but rather due to extended ionized gas emission. Broad-band images reveal, after subtraction of nebular line emission, a compact stellar LSB component extending slightly beyond the SF regions. This stellar host, being blue over a radius range of 5 exponential scale lengths and showing little colour contrast to the SF component, differs strikingly from the red LSB host of standard BCDs. This fact, in connection with the blue colors of component I Zw 18 C, suggests that most of the stellar mass in I Zw 18 has formed within the last 0.5 Gyr. Furthermore, we show that the exponential intensity fall-off in the filamentary ionized envelope of I Zw 18 is not particular to this system but a common property of the ionized halo of many SF dwarf galaxies on galactocentric distances of several kpc. In the absence of an appreciable underlying stellar background, extended ionized gas emission dominates in the periphery of I Zw 18, mimicking an exponential stellar disc on optical surface brightness profiles.Comment: 24 pages, 16 figures; accepted for publication in Astronomy & Astrophysics; higher resolution images available at http://alpha.uni-sw.gwdg.de/~papade/IZw18

    Pulmonary tuberculosis in the central prison of Douala, Cameroon

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    Objective: To determine the prevalence of and factors associated with pulmonary tuberculosis (PTB) in an urban prison in sub-Saharan Africa.Design: A cross-sectional survey. Setting: The Central Prison of Douala, Cameroon. Results: Two thousand four hundred and seventy four (87.4%) out of 2830 inmates underwent screening. Twenty seven (1.1%) of the inmates were under treatment for smear-positive PTB on commencement of the survey while 60 (2.4%) were diagnosed with smear and/or culture-positive PTB during the active case finding, resulting in a point prevalence of PTB of 3.5%. HIV seroprevalence in inmates without clinical signs of PTB was 111/1067 (10.4%) while it amounted to 6/24 (25%) in PTB patients. In multiple stepwise regression analysis, a low BMl, a prison stay of ≤12 months, and a history of previous incarceration were positively associated with PTB. Conclusion: The study results confirm the high prevalence rates of PTB in prison populations and underscore the need for urgent preventive measures. East African Medical Journal Vol. 83(1) 2006: 25-3

    The stellar host in blue compact dwarf galaxies: the need for a two-dimensional fit

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    The structural properties of the low surface brightness stellar host in blue compact dwarf galaxies are often studied by fitting r^{1/n} models to the outer regions of their radial profiles. The limitations imposed by the presence of a large starburst emission overlapping the underlying component makes this kind of analysis a difficult task. We propose a two-dimensional fitting methodology in order to improve the extraction of the structural parameters of the LSB host. We discuss its advantages and weaknesses by using a set of simulated galaxies and compare the results for a sample of eight objects with those already obtained using a one-dimensional technique. We fit a PSF convolved Sersic model to synthetic galaxies, and to real galaxy images in the B, V, R filters. We restrict the fit to the stellar host by masking out the starburst region and take special care to minimize the sky-subtraction uncertainties. In order to test the robustness and flexibility of the method, we carry out a set of fits with synthetic galaxies. Furthermore consistency checks are performed to assess the reliability and accuracy of the derived structural parameters. The more accurate isolation of the starburst emission is the most important advantage and strength of the method. Thus, we fit the host galaxy in a range of surface brightness and in a portion of area larger than in previous published 1D fits with the same dataset. We obtain robust fits for all the sample galaxies, all of which, except one, show Sersic indices n very close to 1, with good agreement in the three bands. These findings suggest that the stellar hosts in BCDs have near-exponential profiles, a result that will help us to understand the mechanisms that form and shape BCD galaxies, and how they relate to the other dwarf galaxy classes.Comment: 22 pages, 15 figures (low resolution), accepted for publication in A&A. A higher resolution version of the figures can be provided upon reques

    Emission-Line Galaxies from the Hubble Space Telescope Probing Evolution and Reionization Spectroscopically (PEARS) Grism Survey. II: The Complete Sample

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    We present a full analysis of the Probing Evolution And Reionization Spectroscopically (PEARS) slitess grism spectroscopic data obtained with the Advanced Camera for Surveys on HST. PEARS covers fields within both the Great Observatories Origins Deep Survey (GOODS) North and South fields, making it ideal as a random survey of galaxies, as well as the availability of a wide variety of ancillary observations to support the spectroscopic results. Using the PEARS data we are able to identify star forming galaxies within the redshift volume 0< z<1.5. Star forming regions in the PEARS survey are pinpointed independently of the host galaxy. This method allows us to detect the presence of multiple emission line regions (ELRs) within a single galaxy. 1162 Ha, [OIII] and/or [OII] emission lines have been identified in the PEARS sample of ~906 galaxies down to a limiting flux of ~1e-18 erg/s/cm^2. The ELRs have also been compared to the properties of the host galaxy, including morphology, luminosity, and mass. From this analysis we find three key results: 1) The computed line luminosities show evidence of a flattening in the luminosity function with increasing redshift; 2) The star forming systems show evidence of disturbed morphologies, with star formation occurring predominantly within one effective (half-light) radius. However, the morphologies show no correlation with host stellar mass; and 3) The number density of star forming galaxies with M_* > 1e9} M_sun decreases by an order of magnitude at z<0.5 relative to the number at 0.5<z<0.9 in support of the argument for galaxy downsizing.Comment: Submitted. 48 pages. 19 figures. Accepted to Ap

    Interplay of ‘induced fit’ and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch

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    Riboswitches are highly structured elements in the 5′-untranslated regions (5′-UTRs) of messenger RNA that control gene expression by specifically binding to small metabolite molecules. They consist of an aptamer domain responsible for ligand binding and an expression platform. Ligand binding in the aptamer domain leads to conformational changes in the expression platform that result in transcription termination or abolish ribosome binding. The guanine riboswitch binds with high-specificity to guanine and hypoxanthine and is among the smallest riboswitches described so far. The X-ray-structure of its aptamer domain in complex with guanine/hypoxanthine reveals an intricate RNA-fold consisting of a three-helix junction stabilized by long-range base pairing interactions. We analyzed the conformational transitions of the aptamer domain induced by binding of hypoxanthine using high-resolution NMR-spectroscopy in solution. We found that the long-range base pairing interactions are already present in the free RNA and preorganize its global fold. The ligand binding core region is lacking hydrogen bonding interactions and therefore likely to be unstructured in the absence of ligand. Mg(2+)-ions are not essential for ligand binding and do not change the structure of the RNA-ligand complex but stabilize the structure at elevated temperatures. We identified a mutant RNA where the long-range base pairing interactions are disrupted in the free form of the RNA but form upon ligand binding in an Mg(2+)-dependent fashion. The tertiary interaction motif is stable outside the riboswitch context

    A HST study of the stellar populations in the cometary dwarf irregular galaxy NGC 2366

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    We present V and I photometry of the resolved stars in the cometary dwarf irregular galaxy NGC 2366, using Wide Field Planetary Camera 2 images obtained with the Hubble Space Telescope. The resulting color-magnitude diagram reaches down to I~26.0 mag. It reveals not only a young population of blue main-sequence stars (age <30 Myr) but also an intermediate-age population of blue and red supergiants (20 Myr<age<100 Myr), and an older evolved populations of asymptotic giant branch (AGB) stars (age >100 Myr) and red giant branch (RGB) stars (age >1 Gyr). The measured magnitude I=23.65+/-0.10 mag of the RGB tip results in a distance modulus m-M=27.67+/-0.10, which corresponds to a distance of 3.42+/-0.15 Mpc, in agreement with previous distance determinations. The youngest stars are associated with the bright complex of HII regions NGC 2363=Mrk 71 in the southwest extremity of the galaxy. As a consequence of the diffusion and relaxation processes of stellar ensembles, the older the stellar population is, the smoother and more extended is its spatial distribution. An underlying population of older stars is found throughout the body of NGC 2366. The most notable feature of this older population is the presence of numerous relatively bright AGB stars. The number ratio of AGB to RGB stars and the average absolute brightness of AGB stars in NGC 2366 are appreciably higher than in the BCD VII Zw 403, indicating a younger age of the AGB stars in NGC 2366. In addition to the present burst of age <100 Myr, there has been strong star formation activity in the past of NGC 2366, from ~100 Myr to <3 Gyr ago.Comment: 32 pages, 15 figures, accepted for publication in the Astrophysical Journa

    Spectroscopic and photometric studies of low-metallicity star-forming dwarf galaxies. I. SBS 1129+576

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    Spectroscopy and V,I CCD photometry of the dwarf irregular galaxy SBS 1129+576 are presented for the first time. The CCD images reveal a chain of compact H II regions within the elongated low-surface-brightness (LSB) component of the galaxy. Star formation takes place mainly in two high-surface-brightness H II regions. The mean (V-I) colour of the LSB component in the surface brightness interval between 23 and 26 mag/sq.arcsec is relatively blue ~0.56+/-0.03 mag, as compared to the (V-I)~0.9-1.0 for the majority of known dwarf irregular and blue compact dwarf (BCD) galaxies. Spectroscopy shows that the galaxy is among the most metal-deficient galaxies with an oxygen abundance 12+log(O/H)= 7.36+/-0.10 in the brightest H II region and 7.48+/-0.12 in the second brightest H II region, or 1/36 and 1/28 of the solar value, respectively. Hbeta and Halpha emission lines and Hdelta and Hgamma absorption lines are detected in a large part of the LSB component. We use two extinction-insensitive methods based on the equivalent widths of (1) emission and (2) absorption Balmer lines to put constraints on the age of the stellar populations in the galaxy. In addition, we use two extinction-dependent methods based on (3) the spectral energy distribution (SED) and (4) the (V-I) colour. The observed properties of the LSB component can be reproduced by a stellar population forming continuously since 10 Gyr ago, provided that the star formation rate has increased during the last 100 Myr by a factor of 6 to 50 and no extinction is present. However, the observational properties of the LSB component can be reproduced equally well by continuous star formation which started not earlier than 100 Myr ago and stopped at 5 Myr, if some extinction is assumed.(Abridged)Comment: 17 pages, 12 figures, Accepted for publication in A&

    The Persistence of Cool Galactic Winds in High Stellar Mass Galaxies Between z~1.4 and ~1

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    We present an analysis of the MgII 2796, 2803 and FeII 2586, 2600 absorption line profiles in coadded spectra of 468 galaxies at 0.7 < z < 1.5. The galaxy sample, drawn from the Team Keck Treasury Redshift Survey of the GOODS-N field, has a range in stellar mass (M_*) comparable to that of the sample at z~1.4 analyzed in a similar manner by Weiner et al. (2009; W09), but extends to lower redshifts and has specific star formation rates which are lower by ~0.6 dex. We identify outflows of cool gas from the Doppler shift of the MgII absorption lines and find that the equivalent width (EW) of absorption due to outflowing gas increases on average with M_* and star formation rate (SFR). We attribute the large EWs measured in spectra of the more massive, higher-SFR galaxies to optically thick absorbing clouds having large velocity widths. The outflows have hydrogen column densities N(H) > 10^19.3 cm^-2, and extend to velocities of ~500 km/s. While galaxies with SFR > 10 Msun/yr host strong outflows in both this and the W09 sample, we do not detect outflows in lower-SFR (i.e., log M_*/Msun < 10.5) galaxies at lower redshifts. Using a simple galaxy evolution model which assumes exponentially declining SFRs, we infer that strong outflows persist in galaxies with log M_*/Msun > 10.5 as they age between z=1.4 and z~1, presumably because of their high absolute SFRs. Finally, using high resolution HST/ACS imaging in tandem with our spectral analysis, we find evidence for a weak trend (at 1 sigma significance) of increasing outflow absorption strength with increasing galaxy SFR surface density.Comment: Submitted to ApJ. 25 pages, 19 figures, Figure 2 reduced in resolution. Uses emulateapj forma
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