Supernova PTF12glz: a possible shock breakout driven through an aspherical wind

We present visible-light and ultraviolet (UV) observations of the supernova PTF12glz. The SN was discovered and monitored in near-UV and R bands as part of a joint GALEX and Palomar Transient Factory campaign. It is among the most energetic Type IIn supernovae observed to date (~10^51erg). If the radiated energy mainly came from the thermalization of the shock kinetic energy, we show that PTF12glz was surrounded by ~1 solar mass of circumstellar material (CSM) prior to its explosive death. PTF12glz shows a puzzling peculiarity: at early times, while the freely expanding ejecta are presumably masked by the optically thick CSM, the radius of the blackbody that best fits the observations grows at ~8000km/s. Such a velocity is characteristic of fast moving ejecta rather than optically thick CSM. This phase of radial expansion takes place before any spectroscopic signature of expanding ejecta appears in the spectrum and while both the spectroscopic data and the bolometric luminosity seem to indicate that the CSM is optically thick. We propose a geometrical solution to this puzzle, involving an aspherical structure of the CSM around PTF12glz. By modeling radiative diffusion through a slab of CSM, we show that an aspherical geometry of the CSM can result in a growing effective radius. This simple model also allows us to recover the decreasing blackbody temperature of PTF12glz. SLAB-Diffusion, the code we wrote to model the radiative diffusion of photons through a slab of CSM and evaluate the observed radius and temperature, is made available on-line.Comment: Sumbitted to ApJ. Comments are welcom

Kondo effect in coupled quantum dots: a Non-crossing approximation study

The out-of-equilibrium transport properties of a double quantum dot system in the Kondo regime are studied theoretically by means of a two-impurity Anderson Hamiltonian with inter-impurity hopping. The Hamiltonian, formulated in slave-boson language, is solved by means of a generalization of the non-crossing approximation (NCA) to the present problem. We provide benchmark calculations of the predictions of the NCA for the linear and nonlinear transport properties of coupled quantum dots in the Kondo regime. We give a series of predictions that can be observed experimentally in linear and nonlinear transport measurements through coupled quantum dots. Importantly, it is demonstrated that measurements of the differential conductance ${\cal G}=dI/dV$, for the appropriate values of voltages and inter-dot tunneling couplings, can give a direct observation of the coherent superposition between the many-body Kondo states of each dot. This coherence can be also detected in the linear transport through the system: the curve linear conductance vs temperature is non-monotonic, with a maximum at a temperature $T^*$ characterizing quantum coherence between both Kondo states.Comment: 20 pages, 17 figure

Supernova PTF 12glz: A Possible Shock Breakout Driven through an Aspherical Wind

We present visible-light and ultraviolet (UV) observations of the supernova PTF 12glz. The SN was discovered and monitored in the near-UV and R bands as part of a joint GALEX and Palomar Transient Factory campaign. It is among the most energetic SNe IIn observed to date (≈10^(51) erg). If the radiated energy mainly came from the thermalization of the shock kinetic energy, we show that PTF 12glz was surrounded by ~1 M⊙ of circumstellar material (CSM) prior to its explosive death. PTF 12glz shows a puzzling peculiarity: at early times, while the freely expanding ejecta are presumably masked by the optically thick CSM, the radius of the blackbody that best fits the observations grows at ≈7000 km s^(−1). Such a velocity is characteristic of fast moving ejecta rather than optically thick CSM. This phase of radial expansion takes place before any spectroscopic signature of expanding ejecta appears in the spectrum and while both the spectroscopic data and the bolometric luminosity seem to indicate that the CSM is optically thick. We propose a geometrical solution to this puzzle, involving an aspherical structure of the CSM around PTF 12glz. By modeling radiative diffusion through a slab of CSM, we show that an aspherical geometry of the CSM can result in a growing effective radius. This simple model also allows us to recover the decreasing blackbody temperature of PTF 12glz. SLAB-Diffusion, the code we wrote to model the radiative diffusion of photons through a slab of CSM and evaluate the observed radius and temperature, is made available online

A Data-Driven Strategy for Identifying Individuals Resistant to SARS-CoV-2 Virus under In-Household Exposure

This report describes the development of a data-driven approach for identifying individuals who tested negative to a SARS-CoV-2 infection, despite their residence with individuals who had confirmed infections. Household studies have demonstrated efficiency in evaluating exposure to SARS-CoV-2. Leveraging earlier studies based on the household unit, our analysis utilized close contacts in order to trace chains of infection and to subsequently categorize TEFLONs, an acronym for Timely Exposed to Family members Leaving One Not infected. We used over one million anonymized electronic medical records, retrieved from Maccabi Healthcare Services’ centralized computerized database from March 2020 to March 2022. The analysis yielded 252 TEFLONs, who were probably at very high risk of infection and yet, demonstrated clinical resistance. The exposure extent in each household positively correlated with household size, reflecting the in-house rolling transmission event. Our approach can be easily implemented in other clinical fields and should spur further research of clinical resistance to various infections

Domain Analysis of the Chloroplast Polynucleotide Phosphorylase Reveals Discrete Functions in RNA Degradation, Polyadenylation, and Sequence Homology with Exosome Proteins

The molecular mechanism of mRNA degradation in the chloroplast consists of sequential events, including endonucleolytic cleavage, the addition of poly(A)-rich sequences to the endonucleolytic cleavage products, and exonucleolytic degradation. In spinach chloroplasts, the latter two steps of polyadenylation and exonucleolytic degradation are performed by the same phosphorolytic and processive enzyme, polynucleotide phosphorylase (PNPase). An analysis of its amino acid sequence shows that the protein is composed of two core domains related to RNase PH, two RNA binding domains (KH and S1), and an α-helical domain. The amino acid sequence and domain structure is largely conserved between bacteria and organelles. To define the molecular mechanism that controls the two opposite activities of this protein in the chloroplast, the ribonuclease, polymerase, and RNA binding properties of each domain were analyzed. The first core domain, which was predicted to be inactive in the bacterial enzymes, was active in RNA degradation but not in polymerization. Surprisingly, the second core domain was found to be active in degrading polyadenylated RNA only, suggesting that nonpolyadenylated molecules can be degraded only if tails are added, apparently by the same protein. The poly(A) high-binding-affinity site was localized to the S1 domain. The complete spinach chloroplast PNPase, as well as versions containing the core domains, complemented the cold sensitivity of an Escherichia coli PNPase-less mutant. Phylogenetic analyses of the two core domains showed that the two domains separated very early, resulting in the evolution of the bacterial and organelle PNPases and the exosome proteins found in eukaryotes and some archaea

Alopecia, Neurological Defects, and Endocrinopathy Syndrome Caused by Decreased Expression of RBM28, a Nucleolar Protein Associated with Ribosome Biogenesis

Single-gene disorders offer unique opportunities to shed light upon fundamental physiological processes in humans. We investigated an autosomal-recessive phenotype characterized by alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome). By using homozygosity mapping and candidate-gene analysis, we identified a loss-of-function mutation in RBM28, encoding a nucleolar protein. RBM28 yeast ortholog, Nop4p, was previously found to regulate ribosome biogenesis. Accordingly, electron microscopy revealed marked ribosome depletion and structural abnormalities of the rough endoplasmic reticulum in patient cells, ascribing ANE syndrome to the restricted group of inherited disorders associated with ribosomal dysfunction

Portaria 078/CSE/2017 - Designa servidores para comporem Comissão Eleitoral

We present visible-light and ultraviolet (UV) observations of the supernova PTF12glz. The SN was discovered and monitored in near-UV and R bands as part of a joint GALEX and Palomar Transient Factory campaign. It is among the most energetic Type IIn supernovae observed to date (~10^51erg). If the radiated energy mainly came from the thermalization of the shock kinetic energy, we show that PTF12glz was surrounded by ~1 solar mass of circumstellar material (CSM) prior to its explosive death. PTF12glz shows a puzzling peculiarity: at early times, while the freely expanding ejecta are presumably masked by the optically thick CSM, the radius of the blackbody that best fits the observations grows at ~8000km/s. Such a velocity is characteristic of fast moving ejecta rather than optically thick CSM. This phase of radial expansion takes place before any spectroscopic signature of expanding ejecta appears in the spectrum and while both the spectroscopic data and the bolometric luminosity seem to indicate that the CSM is optically thick. We propose a geometrical solution to this puzzle, involving an aspherical structure of the CSM around PTF12glz. By modeling radiative diffusion through a slab of CSM, we show that an aspherical geometry of the CSM can result in a growing effective radius. This simple model also allows us to recover the decreasing blackbody temperature of PTF12glz. SLAB-Diffusion, the code we wrote to model the radiative diffusion of photons through a slab of CSM and evaluate the observed radius and temperature, is made available on-line