Modeling and researching the process of plasmachemical recycling of oil wastes based on polychlorinated biphenyls

Theses represents results on thermodynamic simulation of plasmachemical recycling of dielectric oil wastes in air plasma in form of water-organic compositions having optimal composition, lower calorific value minimum 8,4 MJ/kg and adiabatic combustion temperature minimum 1200 °С

PICA Performance by Traumatically Brain Injured and Left Hemisphere CVA Patients

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Appraisal and Diagnosis of Neurogenic Communication Disorders in Remote Settings

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Expression determinants of mammalian argonaute proteins in mediating gene silencing

RNA interference occurs by two main processes: mRNA site-specific cleavage and non-cleavage-based mRNA degradation or translational repression. Site-specific cleavage is carried out by argonaute-2 (Ago2), while all four mammalian argonaute proteins (Ago1–Ago4) can carry out non-cleavage-mediated inhibition, suggesting that Ago1, Ago3 and Ago4 may have similar but potentially redundant functions. It has been observed that in mammalian tissues, expression of Ago3 and Ago4 is dramatically lower compared with Ago1; however, an optimization of the Ago3 and Ago4 coding sequences to include only the most common codon at each amino acid position was able to augment the expression of Ago3 and Ago4 to levels comparable to that of Ago1 and Ago2. Thus, we examined whether particular sequence features exist in the coding region of Ago3 and Ago4 that may prevent a high level of expression. Swapping specific sub-regions of wild-type and optimized Ago sequence identified the portion of the coding region (nucleotides 1–1163 for Ago-3 and 1–1494 for Ago-4) that is most influential for expression. This finding has implications for the evolutionary conservation of Ago proteins in the mammalian lineage and the biological role that potentially redundant Ago proteins may have

Practice Guidelines for Teledermatology

Previous American Telemedicine Association (ATA) Teledermatology Practice Guidelines were issued in 2007. This updated version reflects new knowledge in the field, new technologies, and the need to incorporate teledermatology practice in a variety of settings, including hospitals, urgent care centers, Federally Qualified Health Centers, school-based clinics, public health facilities, and patient homes.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140294/1/tmj.2016.0137.pd

Flexible quasi-three-dimensional terahertz electric metamaterials,

Abstract: We fabricate quasi-three-dimensional terahertz electric metamaterials by stacking multiple single-layer planar metamaterials fabricated on thin, flexible polyimide substrates. Terahertz time-domain spectroscopy is used to characterize their transmission properties, with which we obtain the frequency dependent complex effective dielectric functions. Increasing the number of layers reduces the resonant transmission minimum, while the extracted effective dielectric functions are independent on the number of layers. The results reveal that the real portions of the dielectric functions only show positive values, however, decreasing the thickness of the polyimide substrates, and thereby the spacing between the adjacent split-ring resonator layers, enables negative electric response

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could indicate the presence of the potentially lethal mendelian long-QT syndrome (LQTS). Using a genome-wide association and replication study in up to 100,000 individuals, we identified 35 common variant loci associated with QT interval that collectively explain ∼8-10% of QT-interval variation and highlight the importance of calcium regulation in myocardial repolarization. Rare variant analysis of 6 new QT interval-associated loci in 298 unrelated probands with LQTS identified coding variants not found in controls but of uncertain causality and therefore requiring validation. Several newly identified loci encode proteins that physically interact with other recognized repolarization proteins. Our integration of common variant association, expression and orthogonal protein-protein interaction screens provides new insights into cardiac electrophysiology and identifies new candidate genes for ventricular arrhythmias, LQTS and SCD