Diagnosis of IgG4-related systemic disease by cytology of large pericardial effusion with fine needle aspiration

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研修医指導においてビデオ式McCoy型喉頭鏡が有用であった挿管困難の1症例

雑誌掲載版呼吸不全患者に対する研修医の気管挿管時の困難気道に際して、通常のMacintosh型でCormack 3度、BURP手技でも2bまでしか改善しない症例に遭遇した。ビデオ式McCoy型喉頭鏡を用いて、研修医が直視観察しながら指導者がモニター観察下にMcCoyのレバーを操作し、Cormack 1度の視野を得て挿管した。Macintosh型喉頭鏡での挿管を望む研修者の教育において、通常の手技を妨げずに、視野を共有しながら喉頭所見を改善する手技を付加できる本器具は指導上有用であると考えられた

Polyamine toxins from spiders and wasps

This chapter summarizes all of the naturally occurring polyamine toxins from spider and wasp sources. It discusses the basic problems of their isolation, structure elucidation, and synthesis. It also describes polyamine toxin analogs. Plausible structural variations of the original natural products are outlined and synthetic approaches to the respective artificial target molecules briefly explained. The venoms of spiders and wasps are complex composites of free amino acids, large proteinaceous toxin, and relatively small polyamine toxins. For a long time, the interest in such venoms primarily focused on the high molecular weight components, particularly those extracted from tropical spiders. With the development of improved analytical methodologies and because of the interesting neurotoxic activities of these compounds, the polyamine venom components of common “garden variety” spiders, as well as wasps have gained attention. Several laboratories have concentrated their research on the isolation, structure elucidation, synthesis, and pharmacology of such natural products, as well as the study of synthetic analogs

COMET P/2016 WM48 (Lemmon)

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