The electrochemical and spectroscopic characterization of 1,4 and 1,8-aminoanthraquinone derivatives

The acid base properties of 1,4 and 1,8-anthraquinone derivatives were determined in methanol and acetonitrile by pH-spectroscopic measurements. The examined compounds was also characterized by electrochemically using cyclic voltammetry in DMSO solutions

Influence of substituent on spectroscopic and acid-base properties of anthraquinone derivatives

A series of 1,4-disubstituted aminoanthraquinones has been prepared from 1,4 ditosyloksyanthraquinone. The potentiometric and UV-spectrophotometric method have been used to study the acid-base properties of obtained compounds. The absorption spectra revealed the presence of vibroelectronic band in visible region for compounds containing two tertiary nitrogen groups. It indicates the separation of vibronic states in the molecule. Determined pKa values in acetonitrile used as a solvent indicate the influence of substitution of amino group on basicity of the anthraquinone moiety

Characteristics of multiwalled carbon nanotubes-rhenium nanocomposites with varied rhenium mass fractions

The purpose of the article is to discuss the process of oxidation of carbon nanotubes subsequently subjected to the process of decoration with rhenium nanoparticles. The influence of functionalization in an oxidizing medium is presented and the results of investigations using Raman spectroscopy and infrared spectroscopy are discussed. Multiwalled carbon nanotubes rhenium-type nanocomposites with the weight percentage of 10%, 20% and 30% of rhenium are also presented in the article. The structural components of such nanocomposites are carbon nanotubes decorated with rhenium nanoparticles. Microscopic examinations under transmission electron microscope and scanning transmission electron microscope using the bright and dark field confirm that nanocomposites containing about 20% of rhenium have the most homogenous structure

Methyl 7-meth­oxy-9-oxo-9H-xanthene-2-carboxyl­ate

The crystal structure of the title compound, C16H12O5, is stabilized by C—H⋯O hydrogen bonds and C=O⋯π inter­actions; π–π inter­actions are also present. With respective average deviations from planarity of 0.003 (2) and 0.002 (1) Å, the xanthone and ester fragments are oriented at an angle of 2.8 (2)° with respect to each other. The mean planes of the xanthone skeleton lie either parallel to each other or are inclined at an angle of 85.5 (2)° in the crystal structure

1-Dimethyl­amino-9,10-anthraquinone

In the crystal structure of the title compound, C16H13NO2, adjacent mol­ecules are linked through C—H⋯π and π–π [centroid–centroid distances = 3.844 (2) Å] contacts. The anthracene ring system and dimethyl­amino group are oriented at a dihedral angle of 38.4 (1)°. In the crystal, the mean planes of adjacent anthracene units are inclined at angles of 59.3 (1), 75.7 (1) and 76.0 (1)°

A rapid-response ultrasensitive biosensor for influenza virus detection using antibody modified boron-doped diamond

According to the World Health Organization (WHO), almost 2 billion people each year are infected worldwide with flu-like pathogens including influenza. This is a contagious disease caused by viruses belonging to the family Orthomyxoviridae. Employee absenteeism caused by flu infection costs hundreds of millions of dollars every year. To successfully treat influenza virus infections, detection of the virus during the initial development phase of the infection is critical, when tens to hundreds of virus-associated molecules are present in the patient’s pharynx. In this study, we describe a novel universal diamond biosensor, which enables the specific detection of the virus at ultralow concentrations, even before any clinical symptoms arise. A diamond electrode is surface-functionalized with polyclonal anti-M1 antibodies, which then serve to identify the universal biomarker for the influenza virus, M1 protein. The absorption of the M1 protein onto anti-M1 sites of the electrode change its electrochemical impedance spectra. We achieved a limit of detection of 1 fg/ml in saliva buffer for the M1 biomarker, which corresponds to 5–10 viruses per sample in 5 minutes. Furthermore, the universality of the assay was confirmed by analyzing different strains of influenza A virus

Ankieta na temat reformy ordynacji wyborczej do sejmu i senatu

Digitalizacja i deponowanie archiwalnych zeszytów RPEiS sfinansowane przez MNiSW w ramach realizacji umowy nr 541/P-DUN/201

A rapid-response ultrasensitive biosensor for influenza virus detection using antibody modified boron-doped diamond

According to the World Health Organization (WHO), almost 2 billion people each year are infected worldwide with flu-like pathogens including influenza. This is a contagious disease caused by viruses belonging to the family Orthomyxoviridae. Employee absenteeism caused by flu infection costs hundreds of millions of dollars every year. To successfully treat influenza virus infections, detection of the virus during the initial development phase of the infection is critical, when tens to hundreds of virus-associated molecules are present in the patient’s pharynx. In this study, we describe a novel universal diamond biosensor, which enables the specific detection of the virus at ultralow concentrations, even before any clinical symptoms arise. A diamond electrode is surface-functionalized with polyclonal anti-M1 antibodies, which then serve to identify the universal biomarker for the influenza virus, M1 protein. The absorption of the M1 protein onto anti-M1 sites of the electrode change its electrochemical impedance spectra. We achieved a limit of detection of 1 fg/ml in saliva buffer for the M1 biomarker, which corresponds to 5–10 viruses per sample in 5 minutes. Furthermore, the universality of the assay was confirmed by analyzing different strains of influenza A virus