942 research outputs found
An Underwater Archeological Survey and Assessment of Cultural Resources of the Chicago Bridge and Iron Company\u27s Victoria Bluff Facility, Beaufort County, South Carolina
https://scholarcommons.sc.edu/archanth_books/1095/thumbnail.jp
Literature Search for the Corps of Engineers\u27 Murrell\u27s Inlet Navigation Project
https://scholarcommons.sc.edu/archanth_books/1098/thumbnail.jp
An Interdisciplinary Undergraduate Degree Program in Electronic Commerce
This paper describes an innovative curriculum for an interdisciplinary undergraduate degree program in electronic commerce. Faculty from the disciplines of computer information systems, computer science, operations management, marketing and graphic design collaborated in devising a curriculum that focuses on the business of electronic commerce while providing a solid base of information technology skills. The program includes an integrated junior year experience that gives students business and technical skills in a team-taught environment. During the senior year, students concentrate on technology infrastructure, business processes, or market analysis and development. This paper not only presents a blueprint for an undergraduate curriculum, but also provides a model for faculty cooperation across academic disciplines
Critical single-domain/multidomain grain sizes in noninteracting and interacting elongated magnetite particles: Implications for magnetosomes
Avibactam Pharmacokinetic/Pharmacodynamic Targets
ABSTRACT
Avibactam is a novel non-β-lactam β-lactamase inhibitor that has been approved in the United States and Europe for use in combination with ceftazidime. Combinations of avibactam with aztreonam or ceftaroline fosamil have also been clinically evaluated. Until recently, there has been very little precedence of which pharmacokinetic/pharmacodynamic (PK/PD) indices and magnitudes are appropriate to use for β-lactamase inhibitors in population PK modeling for analyzing potential doses and susceptibility breakpoints. For avibactam, several preclinical studies using different
in vitro
and
in vivo
models have been conducted to identify the PK/PD index of avibactam and the magnitude of exposure necessary for effect in combination with ceftazidime, aztreonam, or ceftaroline fosamil. The PD driver of avibactam critical for restoring the activity of all three partner β-lactams was found to be time dependent rather than concentration dependent and was defined as the time that the concentration of avibactam exceeded a critical concentration threshold (%
f
T>C
T
). The magnitude of the C
T
and the time that this threshold needed to be exceeded to elicit particular PD endpoints varied depending on the model and the partner β-lactam. This review describes the preclinical studies used to determine the avibactam PK/PD target in combination with its β-lactam partners.
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Dressed Bose-Einstein Condensates in High-Q Cavities
We propose and analyze a way in which effective multicomponent condensates
can be created inside high-Q multimode cavities. In contrast to the situation
involving several atomic species or levels, the coupling between the various
components of the dressed condensates is linear. We predict analytically and
numerically confirm the onset of instabilities in the quasiparticle excitation
spectrum.Comment: plain tex, 20 pages, 4 figure
Commentary: Can ordinary people detect deception after all?
No one likes to call someone a liar. But the authors of the tipping point account (ten Brinke, Vohs, & Carney, 2016) claim that it is evolutionary prudent to spot lies that can harm us in order to determine who to trust. As such, they propose the reputational costs of confronting a liar might be overcome by detecting lies unconsciously. When confronted with information that creates a threat response, the unconscious can use the threat response to detect deceptive cues and to unconsciously infer deception, all the while keeping this information out of the conscious mind. The account suggests this is beneficial because conscious awareness of the deception “could impel the perceiver to confront the liar” (p. 580).
The account is controversial insofar as it claims that people can detect deception, in contrast to past work showing otherwise (47% detection rate of lies, and 61% of truths, resulting from bias to judge statements as true: Bond & DePaulo, 2006), and also makes novel claims about an unconscious ability. Although it is welcoming to see new theoretical approaches to lie detection, the account (a) makes claims that do not match the data and conclusions presented in the studies cited to build its case, (b) offers no testable definition of unconscious processes, and (c) contains internal contradictions
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