800 research outputs found
Quasi-periodic attractors, Borel summability and the Bryuno condition for strongly dissipative systems
We consider a class of ordinary differential equations describing
one-dimensional analytic systems with a quasi-periodic forcing term and in the
presence of damping. In the limit of large damping, under some generic
non-degeneracy condition on the force, there are quasi-periodic solutions which
have the same frequency vector as the forcing term. We prove that such
solutions are Borel summable at the origin when the frequency vector is either
any one-dimensional number or a two-dimensional vector such that the ratio of
its components is an irrational number of constant type. In the first case the
proof given simplifies that provided in a previous work of ours. We also show
that in any dimension , for the existence of a quasi-periodic solution with
the same frequency vector as the forcing term, the standard Diophantine
condition can be weakened into the Bryuno condition. In all cases, under a
suitable positivity condition, the quasi-periodic solution is proved to
describe a local attractor.Comment: 10 page
Explicit expressions for meromorphic solution of autonomous nonlinear ordinary differential equations
Meromorphic solutions of autonomous nonlinear ordinary differential equations
are studied. An algorithm for constructing meromorphic solutions in explicit
form is presented. General expressions for meromorphic solutions (including
rational, periodic, elliptic) are found for a wide class of autonomous
nonlinear ordinary differential equations
On a Watson-like Uniqueness Theorem and Gevrey Expansions
We present a maximal class of analytic functions, elements of which are in
one-to-one correspondence with their asymptotic expansions. In recent decades
it has been realized (B. Malgrange, J. Ecalle, J.-P. Ramis, Y. Sibuya et al.),
that the formal power series solutions of a wide range of systems of ordinary
(even non-linear) analytic differential equations are in fact the Gevrey
expansions for the regular solutions. Watson's uniqueness theorem belongs to
the foundations of this new theory. This paper contains a discussion of an
extension of Watson's uniqueness theorem for classes of functions which admit a
Gevrey expansion in angular regions of the complex plane with opening less than
or equal to (\frac \pi k,) where (k) is the order of the Gevrey expansion. We
present conditions which ensure uniqueness and which suggest an extension of
Watson's representation theorem. These results may be applied for solutions of
certain classes of differential equations to obtain the best accuracy estimate
for the deviation of a solution from a finite sum of the corresponding Gevrey
expansion.Comment: 18 pages, 4 figure
Fast projectile stopping power of quantal multi-component strongly coupled plasmas
The Bethe-Larkin formula for the fast projectile stopping power is extended
to multi-component plasmas. The results are to contribute to the correct
interpretation of the experimental data, which could permit to test the
existing and future models of thermodynamic, static, and dynamic
characteristics of strongly coupled Coulomb systems.Comment: 4 pages, to appear in PR
Haplotype analysis in Icelandic and Finnish BRCA2 999del5 breast cancer families
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldThe 999del5 mutation is the single, strong BRCA2 founder mutation in Iceland and the most common BRCA1/2 founder mutation in Finland. To evaluate the origin and time since spreading of the 999del5 mutation in Iceland and in Finland, we constructed haplotypes with polymorphic markers within and flanking the BRCA2 gene in a set of 18 Icelandic and 10 Finnish 999del5 breast cancer families. All Icelandic families analysed shared a common core haplotype of about 1.7 cM. The common ancestors for the Icelandic families studied were estimated to trace back to 340-1000 years, not excluding the possibility that the mutation was brought to Iceland during the settlement of the country. Analysis of the Finnish families revealed two distinct haplotypes. A rare one, found in three families in the old settlement region in southwestern Finland, shared a four-marker (0.5 cM) core haplotype with the Icelandic 999del5 haplotype. A distinct approximately 6 cM haplotype was shared by seven 999del5 Finnish families estimated to have a common ancestry 140-300 years ago. These families cluster in two geographical regions in Finland, in the very same area as those with the rare haplotype and also in the most eastern, late settlement region of Finland. The results may indicate a common ancient origin for the 999del5 mutation in Iceland and in Finland, but distinct mutational events cannot be ruled out. The surprising finding of the same mutation in two completely different haplotypes in a sparsely populated area in Finland may suggest gene conversion
Pseudo-Hermitian Representation of Quantum Mechanics
A diagonalizable non-Hermitian Hamiltonian having a real spectrum may be used
to define a unitary quantum system, if one modifies the inner product of the
Hilbert space properly. We give a comprehensive and essentially self-contained
review of the basic ideas and techniques responsible for the recent
developments in this subject. We provide a critical assessment of the role of
the geometry of the Hilbert space in conventional quantum mechanics to reveal
the basic physical principle motivating our study. We then offer a survey of
the necessary mathematical tools and elaborate on a number of relevant issues
of fundamental importance. In particular, we discuss the role of the antilinear
symmetries such as PT, the true meaning and significance of the charge
operators C and the CPT-inner products, the nature of the physical observables,
the equivalent description of such models using ordinary Hermitian quantum
mechanics, the pertaining duality between local-non-Hermitian versus
nonlocal-Hermitian descriptions of their dynamics, the corresponding classical
systems, the pseudo-Hermitian canonical quantization scheme, various methods of
calculating the (pseudo-) metric operators, subtleties of dealing with
time-dependent quasi-Hermitian Hamiltonians and the path-integral formulation
of the theory, and the structure of the state space and its ramifications for
the quantum Brachistochrone problem. We also explore some concrete physical
applications of the abstract concepts and tools that have been developed in the
course of this investigation. These include applications in nuclear physics,
condensed matter physics, relativistic quantum mechanics and quantum field
theory, quantum cosmology, electromagnetic wave propagation, open quantum
systems, magnetohydrodynamics, quantum chaos, and biophysics.Comment: 76 pages, 2 figures, 243 references, published as Int. J. Geom. Meth.
Mod. Phys. 7, 1191-1306 (2010
Multipoint Schur algorithm and orthogonal rational functions: convergence properties, I
Classical Schur analysis is intimately connected to the theory of orthogonal
polynomials on the circle [Simon, 2005]. We investigate here the connection
between multipoint Schur analysis and orthogonal rational functions.
Specifically, we study the convergence of the Wall rational functions via the
development of a rational analogue to the Szeg\H o theory, in the case where
the interpolation points may accumulate on the unit circle. This leads us to
generalize results from [Khrushchev,2001], [Bultheel et al., 1999], and yields
asymptotics of a novel type.Comment: a preliminary version, 39 pages; some changes in the Introduction,
Section 5 (Szeg\H o type asymptotics) is extende
The stability for the Cauchy problem for elliptic equations
We discuss the ill-posed Cauchy problem for elliptic equations, which is
pervasive in inverse boundary value problems modeled by elliptic equations. We
provide essentially optimal stability results, in wide generality and under
substantially minimal assumptions. As a general scheme in our arguments, we
show that all such stability results can be derived by the use of a single
building brick, the three-spheres inequality.Comment: 57 pages, review articl
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers
Peer reviewedPublisher PD
Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA)
Background: In this study we aimed to evaluate the role of a SNP in intron 1 of the ERCC4 gene (rs744154), previously reported to be associated with a reduced risk of breast cancer in the general population, as a breast cancer risk modifier in BRCA1 and BRCA2 mutation carriers. Methods: We have genotyped rs744154 in 9408 BRCA1 and 5632 BRCA2 mutation carriers from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) and assessed its association with breast cancer risk using a retrospective weighted cohort approach. Results: We found no evidence of association with breast cancer risk for BRCA1 (per-allele HR: 0.98, 95% CI: 0.93–1.04, P=0.5) or BRCA2 (per-allele HR: 0.97, 95% CI: 0.89–1.06, P=0.5) mutation carriers. Conclusion: This SNP is not a significant modifier of breast cancer risk for mutation carriers, though weak associations cannot be ruled out. A Osorio1, R L Milne2, G Pita3, P Peterlongo4,5, T Heikkinen6, J Simard7, G Chenevix-Trench8, A B Spurdle8, J Beesley8, X Chen8, S Healey8, KConFab9, S L Neuhausen10, Y C Ding10, F J Couch11,12, X Wang11, N Lindor13, S Manoukian4, M Barile14, A Viel15, L Tizzoni5,16, C I Szabo17, L Foretova18, M Zikan19, K Claes20, M H Greene21, P Mai21, G Rennert22, F Lejbkowicz22, O Barnett-Griness22, I L Andrulis23,24, H Ozcelik24, N Weerasooriya23, OCGN23, A-M Gerdes25, M Thomassen25, D G Cruger26, M A Caligo27, E Friedman28,29, B Kaufman28,29, Y Laitman28, S Cohen28, T Kontorovich28, R Gershoni-Baruch30, E Dagan31,32, H Jernström33, M S Askmalm34, B Arver35, B Malmer36, SWE-BRCA37, S M Domchek38, K L Nathanson38, J Brunet39, T Ramón y Cajal40, D Yannoukakos41, U Hamann42, HEBON37, F B L Hogervorst43, S Verhoef43, EB Gómez García44,45, J T Wijnen46,47, A van den Ouweland48, EMBRACE37, D F Easton49, S Peock49, M Cook49, C T Oliver49, D Frost49, C Luccarini50, D G Evans51, F Lalloo51, R Eeles52, G Pichert53, J Cook54, S Hodgson55, P J Morrison56, F Douglas57, A K Godwin58, GEMO59,60,61, O M Sinilnikova59,60, L Barjhoux59,60, D Stoppa-Lyonnet61, V Moncoutier61, S Giraud59, C Cassini62,63, L Olivier-Faivre62,63, F Révillion64, J-P Peyrat64, D Muller65, J-P Fricker65, H T Lynch66, E M John67, S Buys68, M Daly69, J L Hopper70, M B Terry71, A Miron72, Y Yassin72, D Goldgar73, Breast Cancer Family Registry37, C F Singer74, D Gschwantler-Kaulich74, G Pfeiler74, A-C Spiess74, Thomas v O Hansen75, O T Johannsson76, T Kirchhoff77, K Offit77, K Kosarin77, M Piedmonte78, G C Rodriguez79, K Wakeley80, J F Boggess81, J Basil82, P E Schwartz83, S V Blank84, A E Toland85, M Montagna86, C Casella87, E N Imyanitov88, A Allavena89, R K Schmutzler90, B Versmold90, C Engel91, A Meindl92, N Ditsch93, N Arnold94, D Niederacher95, H Deißler96, B Fiebig97, R Varon-Mateeva98, D Schaefer99, U G Froster100, T Caldes101, M de la Hoya101, L McGuffog49, A C Antoniou49, H Nevanlinna6, P Radice4,5 and J Benítez1,3 on behalf of CIMB
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