A Unified Approach to the Estimation of Demand for Improved Seed in Developing Agriculture

This paper proposes a new approach for estimating the demand for seed within a developing country context where only improved seeds are sold but adoption rates for improved varieties low. A farmer views an improved seed firstly as a derived input embodying production attributes and secondly, as a technology embodying consumption characteristics. He therefore jointly decides on its adoption and the quantity of seed required to plant a predetermined area. Drawing on the theory of demand for consumption goods characteristics and production input attributes, this paper specified and estimated non-separable household demand and consumption models using data collected from 300 farm households in Zambia during the 2003/04 crop season. The estimated results suggest that adoption rate, distance to market, level of household grain self-sufficiency, seed hand-outs and household wealth are significant in determining farmers' seed purchase decisions. Appropriate intervention strategies for increased over-all improved seed demand are recommended. It is concluded that apart from contributing to the literature on modelling farm level seed demand, the model provides a holistic approach for the joint estimation of determinants of improved variety adoption and seed demand relevant for better targeting to increase the impacts of maize breeding research in developing countries.agricultural household model, consumer goods characteristics, production inputs, technology attributes, non-separability, censored equations, Zambia, Crop Production/Industries, C21, D1, O3, Q12, Q16,

Maintain the Consistency of Auditing Cloud

In day to day life cloud is most essential part. Now cloud storage are use for business purpose the cloud is popular due to their huge amount of advantages the cloud is portable we can able to access the cloud anywhere globally. A cloud service provider maintains much duplication and each piece of data are globally distributed on servers. The main problem of cloud is to handle duplication of data which is too costly to achieve powerful consistency on world wide .In this paper we present a novel consistency service model which contain a large amount of data cloud and multiple audit clouds In The Consistency Service model . a data cloud is maintain by Cloud service Provider (CSP) and the number of user constitute group and that group of user can constitute an audit cloud Which can check whether the data cloud provides the valid level of consistency or not we suggest the 2 level auditing architecture, two level auditing architecture requires a loosely synchronize clock in the audit cloud. Then, design algorithms to quantify the commonality of violations metrics, and the staleness of the value of a read metrics. Finally, a Analytical Auditing Strategy (AAS) to shows as many violations as possible. Thus system performed using a combination of simulations and real cloud deployments to validate Analytical Auditing Strategy (AAS). DOI: 10.17762/ijritcc2321-8169.15012

SYNERGISTIC PROTECTIVE ROLE OF CAFFEINE AND L-ASCORBIC ACID ON LEAD INDUCED PROTEIN CONTENT ALTERATIONS IN VARIOUS TISSUES OF LEMELLIDENS CORRIANUS (LEA)

<p>The present communication deals with individual and synergistic effectiveness of caffeine and L-ascorbic acid in lead induced toxicity in an experimental model, freshwater bivalve, Lamellidens corrianus.The effect on bivalve was studied under nine groups. From each treated and recovery groups, some bivalves were removed and protein contents in selected tissues of bivalves were estimated. The protein level was significantly decreased on exposure to lead while the decrease in presence of caffeine + ascorbic acid was less when exposed simultaneously than when exposed individually. During recovery protein contents recovered and the rate of recovery was faster in caffeine + ascorbic acid exposed bivalves as compared to those recovered individually and in normal water. The probable role of the caffeine (1,3,7- Trimethylexanthine) and L-ascorbic acid is discussed in the paper.</p

Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery

There is an unmet need to develop strategies that allow site-specific delivery of short interfering RNA (siRNA) without any associated toxicity. To address this challenge, we have developed a novel siRNA delivery platform using chemically modified pluronic F108 as an amphiphilic polymer with a releasable bioactive disulfide functionality. The micelles exhibited thermoresponsive properties and showed a hydrodynamic size of similar to 291 nm in DLS and similar to 200-250 nm in SEM at 37 degrees C. The grafting of free disulfide pyridyl groups enhanced the transfection efficiency and was successfully demonstrated in human colon carcinoma (HCT116; 88%) and glioma cell lines (U87; 90%), non-cancerous human dermal fibroblast (HDF; 90%) cells as well as in mouse embryonic stem (mES; 54%) cells. To demonstrate the versatility of our modular nanocarrier design, we conjugated the MDGI receptor targeting COOP peptide on the particle surface that allowed the targeted delivery of the cargo molecules to human patent-derived primary BT-13 gliospheres. Transfection experiments with this design resulted in similar to 65% silencing of STAT3 mRNA in BT-13 gliospheres, while only similar to 20% of gene silencing was observed in the absence of the peptide. We believe that our delivery method solves current problems related to the targeted delivery of RNAi drugs for potential in vivo applications.Peer reviewe

Non-enzymatic glycation of proteins: A cause for complications in diabetes

337-344Diabetes mellitus is one of the most common non-communicable diseases, and is the fifth leading cause of death in most of the developed countries. It can affect nearly every organ and system in the body and may result in blindness, end stage renal disease, lower extremity amputation and increase risk of stroke, ischaemic heart diseases and peripheral vascular disease. Hyperglycemia in diabetes causes non-enzymatic glycation of free amino groups of proteins (of lysine residues) and leads to their structural and functional changes, resulting in complications of the diabetes. Glycation of proteins starts with formation of Shiff’s base, followed by intermolecular rearrangement and conversion into Amadori products. When large amounts of Amadori products are formed, they undergo cross linkage to form a heterogeneous group of protein-bound moieties, termed as advanced glycated end products (AGEs). Rate of these reactions are quite slow and only proteins with large amounts of lysine residues undergo glycation with significant amounts of AGEs. The formation of AGEs is a irreversible process, causing structural and functional changes in protein leading to various complications in diabetes like nephropathy, retinopathy, neuropathy and angiopathy. The present review discusses about role of glycation in various complications of diabetes

A Unified Approach to the Estimation of Demand for Improved Seed in Developing Agriculture

This paper proposes a new approach for estimating the demand for seed within a developing country context where only improved seeds are sold but adoption rates for improved varieties low. A farmer views an improved seed firstly as a derived input embodying production attributes and secondly, as a technology embodying consumption characteristics. He therefore jointly decides on its adoption and the quantity of seed required to plant a predetermined area. Drawing on the theory of demand for consumption goods characteristics and production input attributes, this paper specified and estimated non-separable household demand and consumption models using data collected from 300 farm households in Zambia during the 2003/04 crop season. The estimated results suggest that adoption rate, distance to market, level of household grain self-sufficiency, seed hand-outs and household wealth are significant in determining farmers' seed purchase decisions. Appropriate intervention strategies for increased over-all improved seed demand are recommended. It is concluded that apart from contributing to the literature on modelling farm level seed demand, the model provides a holistic approach for the joint estimation of determinants of improved variety adoption and seed demand relevant for better targeting to increase the impacts of maize breeding research in developing countries