DHLP 1&2: Giraph based distributed label propagation algorithms on heterogeneous drug-related networks

Background and Objective: Heterogeneous complex networks are large graphs consisting of different types of nodes and edges. The knowledge extraction from these networks is complicated. Moreover, the scale of these networks is steadily increasing. Thus, scalable methods are required. Methods: In this paper, two distributed label propagation algorithms for heterogeneous networks, namely DHLP-1 and DHLP-2 have been introduced. Biological networks are one type of the heterogeneous complex networks. As a case study, we have measured the efficiency of our proposed DHLP-1 and DHLP-2 algorithms on a biological network consisting of drugs, diseases, and targets. The subject we have studied in this network is drug repositioning but our algorithms can be used as general methods for heterogeneous networks other than the biological network. Results: We compared the proposed algorithms with similar non-distributed versions of them namely MINProp and Heter-LP. The experiments revealed the good performance of the algorithms in terms of running time and accuracy.Comment: Source code available for Apache Giraph on Hadoo

The Paradigm Examples of Polar Concept in Shakespeareas Hamlet

The present article tries to make a fresh analysis of Shakespeare s touchstone Hamlet taking into consideration the term polar concept argument Polar concept is a postmodern hermeneutical form of reading and analyzing texts which sprung from the mind of the British philosopher and critic Gilbert Ryle Polar concept as a reading strategy is a kind of argument that affirms the understanding of one concept from the mere understanding of its polar opposite English literature is replete with write-ups that tackle readers in a dilemmatic situation and this has always caused the dualistic concepts to come to the fore however in a polar concept strategy understanding occurs because the existence of one concept paves the way for its contrary and consequently leads to a dialectical monism The polar concept as a literary term has played a very crucial role in Shakespeare s Hamlet therefore this study is an attempt to highlight the polarity of different concepts in this tragedy The author believes that by drawing a paradigm of polar concepts throughout Hamlet or any other text readers would be able to enjoy different levels of meanings without being petered out by the dexterity of literary devices andtrope

Negrophobia and Anti-Negritude in Morrison’s The Bluest Eye

Morrison’s The Bluest Eye (1970) stands as an outstanding novel of character regarding the destroying effects of Negrophobia among the black on themselves. Pecola Breedlove’s agony over blue eyes arises from an undeveloped Negritude, and the discord within the black society towards Negrophobia, and a strong fear of her own race. Pecola’s non-reconciliation with her black identity, inflamed by domestic violence and the black societal indifference, craves for blue eyes, the paradigm of whiteness and white beauty. Consequently, she develops an anti-black neurosis because of a feeling of nonexistence both within her community and the white society, although she remains entangled within the interstitial space of blackness and whiteness as in a purgatory of suffering. Her final madness is the culmination of a black human being who is unable to neither accept and defend her Negritude, nor able to transcend to a seemingly higher, but fake, state of being

Foregrounding Achebe’s Things Fall Apart: A Postcolonial Study

Chinua Achebe (1930- ) took to the writing of novels and short stories in order to instill socio-cultural and historical awareness among his readers which had a subtle under-pattern of great validity in changing the life condition and outlook of men and women with a modicum of consciousness and sensibility. He was very much concerned about the fate of a society moving inexorably toward thoroughgoing denigration and the self abasement, which accompanied it. It is in this context that Achebe cautioned his native readers to note that the restricted colonial livelihood was not enough. He held that urgent need was some form of Negritude among the colonized Africa. With this perspective in mind, in this article the treatment of Achebe’s Things Fall Apart, as a literary preserver of the African social-cultural and historical values, is undertaken to be examined.  This article also argues that through this novel Achebe extrapolates the pride in the cultural and religious aspects of the African postcolonial heritage.Key words: Africa; Achebe; Negritude; Identity; Colonizer

Eliot’s Journey of the Magi: the Metaphoric Arabesque of Human Soul in Quest of Reality

The present study is a new attempt to make a religious analysis of Eliot’s touchstone called Journey of the Magi. Thomas Stearns Eliot wrote Journey of the Magi during the Modernist Free Verse era which began in the 1920s and continues on to this day as a part of the Post-Modernist movement. Poems composed during the time period are best known for their originality that makes the critics to brood on them repeatedly. Apart from Eliot’s literary and critical vocations, his Journey of the Magi is of great significance; though the poem, on the surface, portrays the journey of the Magi to find the baby Jesus, the potential Messiah who will bring about redemption to the world, it serves as a metaphoric arabesque for the difficult experiences one has to face in the course of a human soul’s bid to take the religious ascent and crystallize its integration and travel in a spiritual pursuit of faith. This is how Eliot got deeply committed to religion in terms of poetic sensibility though, his critics labeled him as a heterogeneous innovator of postmodern literary form and language. With this hypothesis in mind, in this article the treatment of religious arabesque of the modern man in ascending spirituality and search for reality in the Eliot’s Journey of the Magi is undertaken to be examined.Key words: Religiosity; Quest; Reality; Magi; Soul; JourneyRésumé La présente étude est une nouvelle tentative afin de faire une analyse religieuses de pierre de touche d'Eliot appelé Journey of the Magi. Thomas Stearns Eliot a écrit Voyage des Mages à l'époque Free Verse moderniste qui a commencé dans les années 1920 et continue à ce jour comme une partie du mouvement post-moderniste. Les Poèmes composés pendant la période de temps sont surtout connus pour leur originalité qui fait la critique à ruminer sur eux à plusieurs reprises. En dehors de vocations littéraires et critiques d'Eliot, son voyage des Rois Mages est de grande importance, bien que le poème, à la surface, dépeint le voyage des Rois Mages à trouver l'enfant Jésus, le Messie potentiel qui va apporter la rédemption au monde, il sert une arabesque métaphorique pour les expériences difficiles qu'on a à faire face au cours de la candidature de l'âme humaine de prendre l'ascension religieuse et cristallisent son intégration et de voyage dans une recherche spirituelle de la foi. Voilà comment Eliot s'est profondément attaché à la religion en termes de sensibilité poétique cependant, ses détracteurs lui étiqueté comme un innovateur hétérogène de la forme littéraire postmoderne et la langue. Avec cette hypothèse à l'esprit, dans cet article le traitement de l'arabesque, religieuse de l'homme moderne dans l'ordre croissant de spiritualité et de recherche pour la réalité dans le voyage du Eliot des Mages est entrepris pour être examinés.Mots clés: Religiosité; Quête; Réalité; Mages; Ame; Voyag

Manifestation of Shklovsky’s Defamiliarization and Derredian Différance in the Poetry of Keats and Sipihri

It seems that there is a demonstration of Shklovsky’s defamiliarization in some of Keats’s and Sipihri’s poems; in them they tried to avoid the traditional logics and conventional ways of looking at the world in order to make difference in the locus of their observations. Amazingly, the function of these differences or contrasts can transparently be equated and aligned to what Derrida asserted as différance or to differ and defer. However, these dualistic ways of looking at the world, pave the way for new artistic perceptions which are not revealed promptly, instead, challenge and penetrate the reader’s mind to discover them. Considering such a perspective in mind, this article is to foreground the manifestation of these terms in some of the poems by Keats and Sipihri which does not seem to have received a significant attention by the researchers. The authors of this paper believe that the essence or the motifs in most of the artistic works of these two poets respond to a dualistic notion which is – or might be – an ongoing process in literary criticism.Key words: Keats; Sipihri; Différance;Defamilirization; Contrast; Dualis

Bacterial Heat Shock Protein Activity

Bacteria are exposed to different types of stress in their growth conditions. They have developed appropriate responses, modulated by the re-modeling of protein complexes and by phosphorylation dependent signal transduction systems, to adapt and to survive in a variety range of nature. Proteins are essential components for biologic activity in the eukaryotic and prokaryotic cell. Heat Shock Proteins (HSP) have been identified from various organisms and have critical role in cell hemostasis. Chaperone can sense environment and have different potential role in the organism evolution

THE DIFFÉRENED IN PAUL AUSTER’S CITY OF GLASS: A LYOTARDIAN APPROACH

Postulating on Quinn and the Stillmans’ state of dissipation at theend of Auster’s City of Glass, one can align it with what Lyotard dubs as astate of différend. Lyotard defines différend as a state of clash between twoparties over the distribution of justice which is conventionally made through metanarratives.Since the concept of justice, in Lyotard’s view, has always been in such a waythat there is always justice to one party and injustice to the other one,Lyotard holds that there can be no true justice. Hence Lyotard claims that the appropriatestate of justice in such a condition is the différend, a state of the sublime,of simultaneous pleasure and pain, in which there is no resolution for eitherparty and the clash is always on the run. Extrapolating on this issue, thispaper argues that Quinn and the Stillmans are left in such a state at the endof Auster’s City of Glass, and it is in accordance with the inability oflanguage to signify or to convey meaning effectively as presented by Auster.Quinn develops madness, a consequence of his pain over his identity crisis,while merging as a “Private eye” in the urban world of his pleasure; StillmanSr, suffering the corrupt state of language, finds pleasure and relief in committingsuicide; and Virginia and Peter just vanish, their pleasure or pain being unrepresented,since there is no medium of articulation for their rights. The findings pointto the incommensurability of justice among and specific to these characters alongwith the inability of language to convey any meaning which highlights the stateof the différend that Auster presents. The case remains open as neither party achievesan appropriate justice. Their final disappearance hints to their unpresentablepresences or final painful pleasures