Use of artificial neural networks on the prediction of zootechnical indexes on gestation and farrowing stages of swines

Objetivou-se com este trabalho avaliar a precisão das redes neurais artificiais (RNA) na estimativa das redes neurais artificiais (RNA) na predição de índices zootécnicos, com base em variáveis térmicas e fisiológicas de porcas gestantes. A pesquisa foi realizada entre janeiro e abril de 2005 em uma propriedade de produção industrial de suínos, no setor de gestação, com 27 matrizes primíparas, alojadas em baias individuais e posteriormente na maternidade em baias de parição, onde foram quantificados os índices de produção dos leitões provenientes do estudo. Para tanto, foi implementada uma RNA backpropagation, com uma camada de entrada, uma oculta e uma camada de saída com funções de transferência tangente sigmoidal. A temperatura do ar e a frequência respiratória foram consideradas variáveis de entrada e o peso ao nascimento dos leitões e número de leitões mumificados, como variáveis de saída. A rede treinada apresentou ótimo poder de generalização, o que possibilitou a predição das variáveis-respostas. A caracterização do ambiente da gestação e maternidade foi adequada se comparada aos dados reais, com poucas tendências de sub ou superestimação de alguns valores. A utilização desse sistema especialista para a previsão dos índices zootécnicos é viável, pois o sistema tem bom desempenho para esta aplicação.The objective of this work was to evaluate the precision of Artificial Neural Networks (ANNs) to estimate zootechnical indexes, based on thermal and physiological variables of pregnant sows. This study was carried out from January to April 2005, in a swine industrial production farm in the gestation section with 27 primiparous gilts, allocated in individual pens and after on farrowing pens where it was quantified animal production indexes of piglets from the study. Therefore, an ANN backpropagation was implemented, with one input layer, one hidden layer, and one output layer with tangent sigmoidal transference functions. Air temperature and respiratory frequency were considered as input variables and weight of piglet at birth and the number of mummified piglets as output variables. The trained ANN presented a great generalization power, which enabled the prediction of the answer-variables. Characterization of the environment of gestation and maternity was appropriated if compared to the real data, with few under or overestimated tendencies of some values. The use of this specialist system to predict zootechnical indexes is viable because the system shows a good performance for this use

Alternative sanitizers to paraformaldehyde for incubation of fertile eggs

The aim of this study was to evaluate an ethanolic extract of propolis and clove essential oil as a substitute for paraformaldehyde for the sanitation of fertile eggs. In total, 1,800 hatching eggs (from 40-week-old CPK [Pesadão Vermelho] breeder hens) were randomly distributed among the treatments (grain alcohol, clove essential oil, ethanolic extract of propolis, and paraformaldehyde). Spraying was the application method for all treatments except for paraformaldehyde, for which fumigation was used. The experimental design was a randomized block design with 4 treatments. Analysis of the incubation parameters was based on 6 replications per treatment. The egg weight loss was lower in the eggs treated with ethanolic extract of propolis (8.59 ± 3.34%) than in the eggs treated with grain alcohol (13.40 ± 2.87%), clove essential oil (12.96 ± 3.33%), and paraformaldehyde (13.05 ± 3.24%). The hatchability of the fertile eggs (51.39 ± 5.81%) and the hatchability of the set eggs (44.74 ± 6.79%) were negatively affected by the application of ethanolic extract of propolis. Late mortality of eggs treated was higher than early mortality in the grain alcohol (12.14 ± 4.72%; 2.86 ± 3.30%), clove essential oil (4.60 ± 5.95%; 3.03 ± 3.50%), and ethanolic extract of propolis (36.63 ± 6.60%, 11.98 ± 4.30%) treatments. The eggs treated with clove essential oil (67.90 ± 1.87%), paraformaldehyde (67.80 ± 1.85%), or grain alcohol (67.50 ± 1.92%) presented chick yields as expected. However, due to the high yield of eggs treated with ethanolic extract of propolis (69.25 ± 1.68%), its application at the concentration used in the present research is not recommended. Clove essential oil, when sprayed on fertile eggs as a sanitizing agent, did not differ from paraformaldehyde in relation to hatchery performance parameters

Effects of different egg turning frequencies on incubation efficiency parameters

This study aimed to evaluate the effects of different egg turning frequencies on incubation efficiency parameters. Nine hundred sixty brown fertile eggs, with an average weight of 52.20 ± 0.85 g, from 38-week-old CJD (Carijó Pesadão) breeder hens were randomly distributed among 4 treatments before incubation. Each treatment corresponded to a turning frequency, being 24 (control), 12, 6, or 3 times per day, at an angle of 45°, until day 18 of incubation. The experimental design was a randomized complete block design with 4 treatments. Analysis of the incubation parameters was based on 6 replications per treatment. The eggs that were turned 12, 6, and 3 times per day exhibited a decrease in hatchability of the fertile eggs of 6.61, 15.51, and 19.70%, respectively, when compared with the control group (91.84 ± 2.73%). With a decrease in turning frequency, there was a gradual increase in early (2.84 ± 1.89 to 14.31 ± 1.82%) and late (3.57 ± 1.39 to 8.05 ± 1.24%) mortality rates. An egg turning frequency of 24 times per day during incubation provided high hatchability rates. In contrast, the turning frequencies of 12, 6, and 3 times per day showed significant losses in hatchability

Clove essential oil in the sanitation of fertile eggs

The aim of this study was to evaluate the efficacy of sanitizing fertile eggs with clove essential oil as an alternative to paraformaldehyde; effects on the reduction in eggshell microbial count, incubation yield, and neonatal chick quality were measured. A total of 1,460 brown fertile eggs with a mean weight of 58.64 ± 0.49 g (from 37-wk-old CPK [Pesadão Vermelho] breeder hens) were collected under aseptic conditions and randomly distributed into 4 treatments (nonsanitized and sanitized with grain alcohol, clove essential oil, and paraformaldehyde) before incubation. The count of total aerobic mesophilic bacteria was significantly lower after spraying with clove essential oil (2.30 ± 0.24 log10 CFU/mL) than on nonsanitized eggs (3.49 ± 0.34 log10 CFU/mL) or on eggs sprayed with grain alcohol (3.09 ± 0.14 log10 CFU/mL) but did not differ significantly from the count in the paraformaldehyde group (2.23 ± 0.29 log10 CFU/mL). The hatchability of fertile eggs differed significantly between the studied treatments. The mean values for the eggs treated with clove essential oil (84.69 ± 1.65%) and paraformaldehyde (81.87 ± 3.92%) were statistically similar but were higher than the negative control (74.03 ± 3.58%) and grain alcohol (73.59 ± 2.87%) values. In the Pasgar© score assessment, it was determined that the clove essential oil (9.21 ± 0.89%) had a superior effect on the physical quality of the chicks compared with the effects of the other treatments. Clove essential oil is effective and safe for eggs intended for incubation. Its use as an alternative to paraformaldehyde in the sanitation of fertile eggs is strongly recommended

Spraying hatching eggs with clove essential oil does not compromise the quality of embryos and one-day-old chicks or broiler performance

The objective of this study was to evaluate whether sanitizing hatching eggs with clove essential oil in the preincubation phase affects broiler performance and influences the hatch window and quality of embryos and one-day-old chicks. Hatching eggs (n = 1280; mean weight = 58.64 ± 0.49 g) from a batch of 37-week-old broiler breeder hens of the CPK (Pesadão Vermelho) lineage were randomly distributed into four treatments in the preincubation phase. The treatments consisted of three different sanitization procedures (spraying with grain alcohol, spraying with clove essential oil, and fumigation with paraformaldehyde) and a control treatment (nonsanitized). The lengths of the embryos and one-day-old chicks (one of the parameters used to assess bird quality) were not significantly different among the treatments, with means of 15.30 ± 1.41 and 18.37 ± 0.76 mm, respectively. Body weight, body weight gain, feed consumption, and feed conversion rate in different rearing periods did not differ significantly among the treatments. However, there was a significant difference in the percentage of survivability during the initial period (1 to 28 days) among the treatments. In conclusion, clove essential oil treatment did not negatively affect the quality of embryos and one-day-old chicks or the performance of broilers

DIGESTIBILIDADE DE UMA DIETA CASEIRA E DOIS ALIMENTOS COMERCIAIS, ECONÔMICO E SUPER-PRÊMIO, PARA CÃES

They were compared the coefficients of apparent digestibility (CAD) and the fecal qualityof dogs fed a home-made diet and two dog foods, standard and super-premium. Six adultdogs were distributed in a double latin square desing (3 x 3), with three treatments andthree periods, in a total of six replications per treatment. Tukey’s test was used to comparethe means. The home-made diet presented the highest CAD, not differing only of the CADof acid ether extract of the super-premium food. The standard food was the lowestdigestive, producting more feces. Fecal dry matter of dogs fed home-made diet was lowerthan in the standard and super-premium foods, which did not differ among then. Fecalscore presented low variability among treatments, remaining in the considered ideal range.Home-made diet can be an alternative in the feeding of dogs.Foram comparados os coeficientes de digestibilidade aparente (CDA) e a qualidade dasfezes de cães alimentados com uma dieta caseira e dois alimentos comerciais, econômicoe super-prêmio. Seis cães adultos foram distribuídos em delineamento quadrado latinoduplo (3 x 3), com três tratamentos e três períodos, totalizando seis repetições portratamento. As médias foram comparadas pelo teste Tukey. A dieta caseira apresentou osmaiores CDA, não diferindo apenas do CDA do extrato etéreo ácido do alimento superprêmio.O alimento econômico foi o menos digestível, gerando o maior resíduo fecal. Oteor de matéria seca das fezes dos cães alimentados com a dieta caseira foi menor emrelação aos cães recebendo os alimentos econômico e super-prêmio, os quais nãodiferiram entre si. O escore fecal variou pouco entre os tratamentos, mantendo-se dentrodo considerado ideal. A dieta caseira pode ser uma alternativa na alimentação de cães

A glossary for biometeorology

Here we present, for the first time, a glossary of biometeorological terms. The glossary aims to address the need for a reliable source of biometeorological definitions, thereby facilitating communication and mutual understanding in this rapidly expanding field. A total of 171 terms are defined, with reference to 234 citations. It is anticipated that the glossary will be revisited in coming years, updating terms and adding new terms, as appropriate. The glossary is intended to provide a useful resource to the biometeorology community, and to this end, readers are encouraged to contact the lead author to suggest additional terms for inclusion in later versions of the glossary as a result of new and emerging developments in the field

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity.

Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant

Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial

Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure <= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.Hospital do Coracao (HCor) as part of the Program 'Hospitais de Excelencia a Servico do SUS (PROADI-SUS)'Brazilian Ministry of Healt