Anti-inflammatory and analgesic activity of different fractions of Boswellia serrata

The study was designed to investigate the anti-inflammatory and analgesic effect of different fractions of Boswellia serrata. The effect of different fractions of Boswellia serrata were studied using carrageenan induced paw edema, acetic acid induced writhing response, formalin induced pain, hot plate and tail flick method for studying anti-inflammatory and analgesic activity, respectively. The different fractions of B. serrata, essential oil (10 ml/kg), gum (100 mg/kg, resin (100 mg/kg) oleo-resin (100 mg/kg) and oleo-gum-resin (100 mg/kg) significantly reduces carrageenan induced inflammation in rats and shows analgesic activity, as determined by acetic acid induced writhing response, formalin induced pain, hot plate and tail flick method. The different fractions of B. serrata showed prompt anti-inflammatory and analgesic activity due to the inhibition of 5-lipoxygenase enzyme.Keywords: Analgesic; Boswellia serrata; Inflammation; 5- lipoxygenase; Burseraceae

Intrinsic Ferromagnetic Behavior in Fe-doped Cu2O Octahedra due to Cation Vacancy Defects

Cu2O octahedra doped with Fe ions were prepared by simple room temperature synthesis. They were found to exhibit paramagnetism at room temperature and ferromagnetic behavior at 77 K. The room temperature Mössbauer spectra indicate that iron is present only in the form of paramagnetic Fe2+ ions. The magnetic moments were observed to be increasing with increase of Fe ions in the materials, therefore suggesting that ferromagnetic behavior might have originated from defects created due to the dopant ions and not from the metal ion itself. The photoluminescence and EPR spectra fully supported the existence of the defects in the lattice

Ab Initio study of the structural, electronic, magnetic, and hyperfine properties of GaxFe4 xN (0.00 e x e 1.00) nitrides

The dependence with Ga content (x) of structural, magnetic, and hyperfine properties of GaxFe4–xN compounds has been studied using the full-potential linearized augmented planewave method based on density functional theory. A nonlinear increase of the lattice parameter with x was observed, ascribed to the different metallic radii of Fe and Ga atoms and a magneto-volumetric effect. The magnetic moment per formula unit (Mfu) decreases linearly with x, where the Mfu of GaFe3N is almost half for the corresponding value of γ′-Fe4N, mainly due to the decreasing of magnetic moment of the FeII (3c Wyckoff position) atoms with the number of Ga next nearest neighbors (nnn). The hyperfine parameters of the FeI (1a Wyckoff position) do not change with x, whereas the hyperfine field (Bhf), isomer shift (δ), and quadrupole shift (ε) of the FeII atoms depend linearly with nnn Ga atoms. Furthermore, by use of fixed spin moment calculation to obtain the curve Mfu vs total energy, it was possible to determine that the ground state of GaFe3N belongs to a ferrimagnetic configuration with a lattice parameter similar to the experimental value.Fil: Gil Rebaza, Arles Victor. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Desimoni, Judith. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Kurian, Sajith. Indian Institute of Technology; IndiaFil: Bhattacharyya, Sayan. Indian Institute of Science Education and Research; IndiaFil: Gajbhiye,Namdeo S.. Indian Institute of Technology; India. Indian Institute of Science Education and Research; IndiaFil: Peltzer y Blanca, Eitel Leopoldo. Universidad Nacional de la Plata. Facultad de Ingenieria. Departamento de Electrotecnia. Grupo de Est.s/materiales y Disposit.electronicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin