27 research outputs found
Boost operators in Coulomb-gauge QCD: the pion form factor and Fock expansions in phi radiative decays
In this article we rederive the Boost operators in Coulomb-Gauge Yang-Mills
theory employing the path-integral formalism and write down the complete
operators for QCD. We immediately apply them to note that what are usually
called the pion square, quartic... charge radii, defined from derivatives of
the pion form factor at zero squared momentum transfer, are completely blurred
out by relativistic and interaction corrections, so that it is not clear at all
how to interpret these quantities in terms of the pion charge distribution. The
form factor therefore measures matrix elements of powers of the QCD boost and
Moeller operators, weighted by the charge density in the target's rest frame.
In addition we remark that the decomposition of the eta' wavefunction in
quarkonium, gluonium, ... components attempted by the KLOE collaboration
combining data from phi radiative decays, requires corrections due to the
velocity of the final state meson recoiling against a photon. This will be
especially important if such decompositions are to be attempted with data from
J/psi decays.Comment: 14 pages, 4 figure
An estimate of the flavour singlet contributions to the hyperfine splitting in charmonium
We explore the splitting between flavour singlet and non-singlet mesons in
charmonium. This has implications for the hyperfine splitting in charmonium
D* Production in Deep Inelastic Scattering at HERA
This paper presents measurements of D^{*\pm} production in deep inelastic
scattering from collisions between 27.5 GeV positrons and 820 GeV protons. The
data have been taken with the ZEUS detector at HERA. The decay channel
(+ c.c.) has been used in the study. The
cross section for inclusive D^{*\pm} production with
and is 5.3 \pms 1.0 \pms 0.8 nb in the kinematic region
{ GeV and }. Differential cross
sections as functions of p_T(D^{*\pm}), and are
compared with next-to-leading order QCD calculations based on the photon-gluon
fusion production mechanism. After an extrapolation of the cross section to the
full kinematic region in p_T(D^{*\pm}) and (D^{*\pm}), the charm
contribution to the proton structure function is
determined for Bjorken between 2 10 and 5 10.Comment: 17 pages including 4 figure
Exclusive electroproduction of J/psi mesons at HERA
The exclusive electroproduction of J/psi mesons, ep->epJ/psi, has been
studied with the ZEUS detector at HERA for virtualities of the exchanged photon
in the ranges 0.15<Q^2<0.8 GeV^2 and 2<Q^2<100 GeV^2 using integrated
luminosities of 69 pb^-1 and 83 pb^-1, respectively.The photon-proton
centre-of-mass energy was in the range 30<W<220 GeV and the squared
four-momentum transfer at the proton vertex |t|<1.The cross sections and decay
angular distributions are presented as functions of Q^2, W and t. The effective
parameters of the Pomeron trajectory are in agreement with those found in J/psi
photoproduction. The spin-density matrix elements, calculated from the decay
angular distributions, are consistent with the hypothesis of s-channel helicity
conservation. The ratio of the longitudinal to transverse cross sections,
sigma_L/sigma_T, grows with Q^2, whilst no dependence on W or t is observed.
The results are in agreement with perturbative QCD calculations and exhibit a
strong sensitivity to the gluon distribution in the proton.Comment: 33 pages, 10 figures. Submitted to Nuclear Physics
Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.
Cell death plays a critical role in inflammatory responses. During pyroptosis, inflammatory caspases cleave Gasdermin D (GSDMD) to release an N-terminal fragment that generates plasma membrane pores that mediate cell lysis and IL-1 cytokine release. Terminal cell lysis and IL-1β release following caspase activation can be uncoupled in certain cell types or in response to particular stimuli, a state termed hyperactivation. However, the factors and mechanisms that regulate terminal cell lysis downstream of GSDMD cleavage remain poorly understood. In the course of studies to define regulation of pyroptosis during Yersinia infection, we identified a line of Card19-deficient mice (Card19lxcn) whose macrophages were protected from cell lysis and showed reduced apoptosis and pyroptosis, yet had wild-type levels of caspase activation, IL-1 secretion, and GSDMD cleavage. Unexpectedly, CARD19, a mitochondrial CARD-containing protein, was not directly responsible for this, as an independently-generated CRISPR/Cas9 Card19 knockout mouse line (Card19Null) showed no defect in macrophage cell lysis. Notably, Card19 is located on chromosome 13, immediately adjacent to Ninj1, which was recently found to regulate cell lysis downstream of GSDMD activation. RNA-seq and western blotting revealed that Card19lxcn BMDMs have significantly reduced NINJ1 expression, and reconstitution of Ninj1 in Card19lxcn immortalized BMDMs restored their ability to undergo cell lysis in response to caspase-dependent cell death stimuli. Card19lxcn mice exhibited increased susceptibility to Yersinia infection, whereas independently-generated Card19Null mice did not, demonstrating that cell lysis itself plays a key role in protection against bacterial infection, and that the increased infection susceptibility of Card19lxcn mice is attributable to loss of NINJ1. Our findings identify genetic targeting of Card19 being responsible for off-target effects on the adjacent gene Ninj1, disrupting the ability of macrophages to undergo plasma membrane rupture downstream of gasdermin cleavage and impacting host survival and bacterial control during Yersinia infection
Ocular, Neurologic and Systemic Findings of the Cases with Optic Nerve Hypoplasia
AIM: To describe the associated ocular, neurologic, and systemic findings in a population of children with optic nerve hypoplasia (ONH) and to evaluate the relationship between ocular signs and neurologic findings. METHOD: A retrospective chart review of 53 patients with the diagnosis of ONH seen between December 1998 and September 2012 was performed. All neurodevelopmental anomalies, neuroradiologic findings, endocrinologic and systemic findings were recorded. Poor vision was defined as the visual acuity poorer than logMAR 1.0 or inadequate central steady maintained fixation. RESULTS: Thirty (56.6%) of the 53 children with ONH were boys. Mean age at presentation was 56.2±46.8 months (range; 3 months to 18 years). Poor vision defined for the purpose of this study was found in 47.2% of 53 patients. Thirty-three (62.3%) children had nystagmus. Thirty-four (64.2%) children had strabismus. Thirteen (38.2%) of those with strabismus had esotropia, 20 (58.8%) had exotropia. The total number of the children with neurodevelopmental deficit was 22 (41.5%) in our study. CONCLUSION: The vision of young children with ONH should be monitored at least annually, and any refractive errors should be treated. Neuroimaging of the brain and endocrinologic evaluation is necessary in all cases with ONH