General secondary vocational education as motivation factor of self-education and occupational mobility in Uzbekisan Republic

Author’s consider General Secondary vocational education as motivating factor of self-education, professional mobility and lifelong learningРассматривается всеобщее среднеспециальное профессиональное образование как мотивирующий фактор самообразования, профессиональной мобильности и непрерывного приобретения знани

Primary lymphangiectasia of the gastrointestinal tract

Intestinal lymphangiectasia is a very rare pathology, characterized by the presence of enlarged lymphatic vessels in all layers of the intestinal wall and in the mesentery. As a result, "lymphatic lakes" are formed, through which lymph exudates into the lumen of the intestine. The main manifestation is hypoproteinemic edema. Diagnosis of the disease is based on laboratory-instrumental methods of investigation, including by determining in the stool α-1 antitrypsin as a screening test. Treatment includes: a diet rich in calcium, trace elements, be sure to use medicinal foods enriched with medium chain triglycerides, substitution and symptomatic therapy

The new functional products inclusion in the complex rehabilitation and preventive programs in athletes with musculoskeletal disorders

The review presents an urgent problem of modern sports medicine — the development and inclusion of new nutritive and metabolic food products in the treatment of athletes with injuries and diseases of the musculoskeletal system. The analysis of the main etiological factors of the musculoskeletal disorders in athletes is presented. The study of the anatomical, histological and functional features of the bone-cartilaginous structures in athletes made it possible to establish the priority macro- and micronutrients, which should be the basis in modern specialized and functional food products. Brief composition characteristics of the new canned food “Enmit-beef” and dry protein concentrate “Ostov” (for the drink preparation) are presented. The preliminary results of the use of these functional meat-based products indicate their effectiveness in rehabilitation and treatment of athletes with musculoskeletal disorders

КРИПТОСПОРИДИОЗ ПРИ ИММУНОДЕФИЦИТЕ У НОВОРОЖДЕННЫХ ТЕЛЯТ

The epizootic situation at cryptosporidiosis in the newborn calves are studied. The calves at the age of 15 days in Dagestan are infected by Cryptosporidium spp. at 45,3 %. Direct dependence of calves infection of kolostral immunity is shown. The calves infection raised with fall of level of immunoglobulines in blood serum.Изучена эпизоотическая ситуация по криптоспоридиозу телят. Инвазированность телят до 15-дневного возраста в Республике Дагестан достигала 45,3 %. Показана прямая зависимость инвазированности телят от колострального иммунитета. С понижением уровня иммуноглобулинов в сыворотке крови инвазированность телят повышалась

HI study of the environment around ESO 243-49, the host galaxy of an intermediate mass black hole

The lenticular galaxy ESO 243-49 hosts the ultraluminous X-ray source HLX-1, the best candidate intermediate mass black hole (IMBH) currently known. The environments of IMBHs remain unknown, however the proposed candidates include the nuclei of dwarf galaxies or globular clusters. Evidence at optical wavelengths points at HLX-1 being the remnant of an accreted dwarf galaxy. Here we report the Australia Telescope Compact Array radio observations of HI emission in and around ESO 243-49 searching for signatures of a recent merger event. No HI line emission is detected in ESO 243-49 with a 5$\sigma$ upper limit on the HI gas mass of a few $10^8 M_{\odot}$. A likely reason for this non-detection is the cluster environment depleting ESO 243-49's HI gas reservoir. The upper limit is consistent with an interpretation of HLX-1 as a dwarf satellite of ESO 243-49, however more sensitive observations are required for a detection. We detect ~$5 \times 10^8 M_{\odot}$ of HI gas in the peculiar spiral galaxy AM 0108-462, located at a projected distance of ~170 kpc from ESO 243-49. This amount of HI gas is ~10 times less than in spiral galaxies with similar optical and near-infrared properties in the field, strengthening the conclusion that the cluster environment indeed depletes the HI gas reservoir of these two galaxies. Here we also report observations of AM 0108-462 in several optical and near-infrared bands using the Magellan 6.5 m telescopes, and archival X-ray and ultraviolet observations with XMM-Newton and Swift. These data combined with the HI line data suggest it is likely that AM 0108-462 is experiencing a merger event.Comment: 12 pages, 9 figures, accepted for publication in MNRA

A Comparison of Photometric Redshift Techniques for Large Radio Surveys

Future radio surveys will generate catalogs of tens of millions of radio sources, for which redshift estimates will be essential to achieve many of the science goals. However, spectroscopic data will be available for only a small fraction of these sources, and in most cases even the optical and infrared photometry will be of limited quality. Furthermore, radio sources tend to be at higher redshift than most optical sources (most radio surveys have a median redshift greater than 1) and so a significant fraction of radio sources hosts differ from those for which most photometric redshift templates are designed. We therefore need to develop new techniques for estimating the redshifts of radio sources. As a starting point in this process, we evaluate a number of machine-learning techniques for estimating redshift, together with a conventional template-fitting technique. We pay special attention to how the performance is affected by the incompleteness of the training sample and by sparseness of the parameter space or by limited availability of ancillary multiwavelength data. As expected, we find that the quality of the photometric-redshift degrades as the quality of the photometry decreases, but that even with the limited quality of photometry available for all-sky-surveys, useful redshift information is available for the majority of sources, particularly at low redshift. We find that a template-fitting technique performs best in the presence of high-quality and almost complete multi-band photometry, especially if radio sources that are also X-ray emitting are treated separately, using specific templates and priors. When we reduced the quality of photometry to match that available for the EMU all-sky radio survey, the quality of the template-fitting degraded and became comparable to some of the machine-learning methods. Machine learning techniques currently perform better at low redshift than at high redshift, because of incompleteness of the currently available training data at high redshifts

Comparison of REMS, NEWS, qSOFA and SIRS criteria scales for sepsis prediction in patients with diagnosis “SARS-CoV-2, virus unidentified”: a retrospective observational study

Background. Despite ample research on the coronavirus infection sequence and therapy, the incidence of adverse outcomes remains very high. Sepsis stands among the major factors greatly complicating treatment and increasing the risk of death. A timely identification of highrisk sepsis patients is a cornerstone of effective sepsis prevention.Objectives. A comparative prognostic power assessment between the quick Sequential Organ Failure Assessment (qSOFA) scale, National Early Warning Score (NEWS), Initial Prehospital Rapid Emergency Medicine Score (REMS) and the Systemic Inflammatory Response Syndrome (SIRS) criteria for sepsis detection in anaesthetic intensive care patients with a diagnosis: SARS-CoV-2, virus unidentified.Methods. A retrospective observational study included 166 patients over 18-year age with unconfirmed infection (ICD-10 code U07.2). The qSOFA, NEWS, REMS and SIRS point estimates were obtained from each patient. The patients were retrospectively divided in two cohorts by sepsis presence (Sepsis-3 criteria) to determine the express scales power in evaluating the risk of sepsis (estimated as area under ROC curve, AUROC).Results. Data on 102 patients were included in the final analysis. Fifty-eight (57%) patients were terminal, and 55 (54%) developed sepsis. The estimates are as follows: NEWS — AUROC 0.848 [95% confidence interval (CI) 0.764–0.912], sensitivity 76.36% [95% CI 63.0–86.8], specificity 82.98% [95% CI 69.2–92.4], optimal cut-off threshold >5 points; qSOFA — AUROC 0.700 [95% CI 0.602–0.787], sensitivity 76.36% [95% CI 63.0–86.8], specificity 61.70% [95% CI 46.4–75.5], optimal cut-off threshold >0 points; REMS — AUROC 0.739 [95% CI 0.643–0.821], sensitivity 69.09% [95% CI 55.2–80.9], specificity 65.96% [95% CI 50.7–79.1], optimal cut-off threshold >5 points; SIRS criteria — AUROC 0.723 [95% CI 0.626–0.807], sensitivity 98.18% [95% CI 90.3–100.0], specificity 31.91% [95% CI 19.1–47.1], optimal cut-off threshold >0 points.Conclusion. The NEWS scale revealed a good prognostic power to estimate the risk of sepsis in patients with suspected COVID-19 disease. The qSOFA, REMS scales and SIRS criteria possess a good calibration capacity, albeit insufficient resolution, which limits their prognostic value

A comparison of photometric redshift techniques for large radio surveys

Future radio surveys will generate catalogs of tens of millions of radio sources, for which redshift estimates will be essential to achieve many of the science goals. However, spectroscopic data will be available for only a small fraction of these sources, and in most cases even the optical and infrared photometry will be of limited quality. Furthermore, radio sources tend to be at higher redshift than most optical sources (most radio surveys have a median redshift greater than 1) and so a significant fraction of radio sources hosts differ from those for which most photometric redshift templates are designed. We therefore need to develop new techniques for estimating the redshifts of radio sources. As a starting point in this process, we evaluate a number of machine-learning techniques for estimating redshift, together with a conventional template-fitting technique. We pay special attention to how the performance is affected by the incompleteness of the training sample and by sparseness of the parameter space or by limited availability of ancillary multiwavelength data. As expected, we find that the quality of the photometric-redshift degrades as the quality of the photometry decreases, but that even with the limited quality of photometry available for all-sky-surveys, useful redshift information is available for the majority of sources, particularly at low redshift. We find that a template-fitting technique performs best in the presence of high-quality and almost complete multi-band photometry, especially if radio sources that are also X-ray emitting are treated separately, using specific templates and priors. When we reduced the quality of photometry to match that available for the EMU all-sky radio survey, the quality of the template-fitting degraded and became comparable to some of the machine-learning methods. Machine learning techniques currently perform better at low redshift than at high redshift, because of incompleteness of the currently available training data at high redshifts

ВЛИЯНИЕ ФУНКЦИОНАЛЬНОГО СОСТОЯНИЯ ПАЦИЕНТОВ ПОЖИЛОГО И СТАРЧЕСКОГО ВОЗРАСТА НА ЧАСТОТУ ИНТРАОПЕРАЦИОННЫХ КРИТИЧЕСКИХ ИНЦИДЕНТОВ

The correlation between the age and wakefulness level evaluated as per the value of constant potential and  frequency of critical incidence occurrence has been investigated in 160 patients who had planned surgery with combined anesthesia due to the colon tumor. The latter depended on the age, it was the lowest in the high level of wakefulness and it was high in the low level of wakefulness regardless of the age. У 160 пациентов, планово оперированных в условиях сочетанной анестезии по поводу опухолей толстой кишки, изучена связь возраста и уровня бодрствования, оценённого по величине постоянного потенциала, с частотой развития критических инцидентов. Последняя зависела от возраста, была наименьшей при высоком уровне бодрствования, а при низком уровне бодрствования оказалась высокой независимо от возраста

РАСПРОСТРАНЕНИЕ И ПРОФИЛАКТИКА ПИРОПЛАЗМИДОЗОВ КРУПНОГО РОГАТОГО СКОТА В РЕСПУБЛИКЕ ДАГЕСТАН

Objective of research: Determination of the efficiency of 5% concentration Diminazene aceturate at the dose of 0.25 mg/kg body in combination with polyethylene glycol solution applied against piroplasmidosis in cattle.Materials and methods: Trial of the new method of prolonged chemoprevention was carried out in one of the farms of Dagestan, which is unfavorable for piroplasmidosis. Aceturate contained in this drug rapidly inhibits DNA in cells of blood parasites, which leads to their death within several hours. Diminazene aceturate proved to be effective against piroplasmidosis, babesiosis, taleriosis, hemosporidosis of animals. The experiment was conducted on 30 head of cattle divided into 3 groups 10 head in each. Animals of two groups received the preparation and prolongator at the dose of 0,25 mg/kg in the 15% aqueous solutions of polyethylene glycols (PEG), and at the dose of 0,25 mg/kg in the 20% aqueous solutions; the third group served as a control (received the preparation without prolongator). Efficacy of the method was estimated by periodic examination of blood smears from experimental animals for plasmodia in erythrocytes and synchronous measurement of body temperature of animals.Results and discussion: It was found that the method of prolonged chemoprophylaxis applied against piroplasmidosis in animals (at the dose of 5 ml per 100 kg body weight, 6 times every 25 days) enables disease prevention during the whole disease season. Such method allows reducing the number of treatments from 24 to 12-13 times in a season. In addition, data on the distribution of hemosporidia infections among the cattle in the Republic of Dagestan were clarified.Цель исследования — изучение эффективности препарата ДАЦ (диминацена ацетурат) в сочетании с 20%-ным раствором полиэтиленгликоля при пироплазмидозах крупного рогатого скота.Материалы и методы. Для испытания нового метода пролонгированной химиопрофилактики был проведен производственный опыт в одном из хозяйств Дагестана, неблагополучном по пироплазмидозу.Входящий в состав препарата ДАЦ диминацена ацетурат быстро ингибирует ДНК клеток паразитов крови, что приводит к их гибели в течение нескольких часов. Препарат ДАЦ является эффективным средством для животных при заболевании пироплазмозом, бабезиозом, тейлериозом, гемоспоридиозом.Опыт проведен на 30 головах крупного рогатого скота, которых разделили на 3 группы по 10 голов в каждой. Животным двух групп вводили препарат и пролонгатор в дозах: 0,25 мг/кг в 15%-ном водном растворе ПЭГ и в дозе 0,25 мг/кг в 20%-ном водном растворе, третья группа служила контролем (препарат без пролонгатора).Эффективность метода определяли путем периодического исследования мазков периферической крови опытных животных на наличие плазмидий в эритроцитах, для мониторинга, синхронно с исследованиями, измеряли температуру тела животных.Результаты и обсуждение. Установлено, что применение метода пролонгированной химиопрофилактики пироплазмоза у крупного рогатого скота в объеме 5 мл на 100 кг массы тела через каждые 25 дней (шестикратно) позволяет предотвратить болезнь в течение всего сезона заболеваний. Такой метод обработки позволяет в последующем сократить количество обработок животных за сезон с 24 до 12-13 раз. Также были уточнены данные по распространению пироплазмидозов крупного рогатого скота в девяти районах Республики Дагестан