Pharmacotherapy exacerbations of chronic inflammatory conditions of female genital sphere using to Gepon and Longidaza

Research objective was establishment of changes of the metabolic status at an aggravation chronic salpingoophoritis and detection of efficiency of use in "Gepon's" complex pharmacotherapy and "Longidaza's" various medicinal form

Integration of the problem of medical ecology on the level of the highly urbanized region

The urgency of the analyzed issue is due to the study of the basic issues of medical ecology: the dynamics of demographic indicators, the correlation of somatic and reproductive public health, depending on the influence of physical factors of the urban environment on public health on the basis of medical and geographic mapping. The article aims at the analysis of the environmentally determined disorder of the urbanized territory. The leading approach to the study of the issue of medical ecology is a medical and geographical mapping, which allows identifying the most affordable and common areas of multi-component medical and environmental maps. While analyzing the impact of various aspects of the environment on human health, the priority is given to risk factors that directly lead to the emergence of diseases. The contents of the article may be useful to justify the choice of the rational approach to public health as a redistribution mechanism to reallocate the space of ecological niches. © 2016 Rozenberg et al

THE DEVELOPMENT OF LOGICAL THINKING IN JUNIOR STUDENTS THROUGH PROJECT-BASED LEARNING

El artículo da una nueva mirada al método de desarrollo del pensamiento lógico en alumnos de tercer año basado en la correlación entre el modelo original y el que hace posible, a diferencia de los métodos tradicionales, desarrollar el pensamiento del habla, las estructuras intelectuales y las operaciones lógicas de los alumnos de manera más efectiva. . Con la ayuda de los enfoques epistemológico, de actividad sistémica y de entorno, se determina una estrategia para desarrollar el pensamiento lógico de los alumnos a través del aprendizaje basado en proyectos que se basa en la correlación entre el modelo original y el original. Asegura el desarrollo efectivo de a) la actividad intelectual de los escolares b) el pensamiento c) la memoria lógica. El estudio demuestra la efectividad de la tecnología presentada, lo que implica 1) sumergirse en el proyecto, así como especificar sus metas y objetivos; 2) organizar y planificar las actividades de los alumnos; 3) resolver las etapas principales del proyecto; 4) llevar a cabo el proyecto y su presentación; 5) evaluar los resultados. Con base en los datos de la investigación, se destacaron los siguientes criterios: análisis, síntesis, comparación, clasificación, generalización y algunos otros criterios que permitieron determinar tres niveles del desarrollo del fenómeno en cuestión. Nuestro método proporciona una mejora significativa de los resultados de la investigación y garantiza la formación de actividades de investigación, informativas, regulatorias y analíticas de aprendizaje universal (ULA). La evaluación de la efectividad y validez del método propuesto se corrobora mediante cálculos para el criterio de Fisher (criterio φ *). Los resultados comparativos de la investigación antes y después del experimento a alto nivel son 3.564. Los valores empíricos obtenidos de φ * están en el área de significancia. H0 se rechaza (el eje de significancia = 1.64–2.31). Por lo tanto, el método en cuestión tiene un grave impacto en el desarrollo del pensamiento lógico a través del aprendizaje basado en proyectos de alumnos menores.O artigo analisa o método de desenvolver o raciocínio lógico em alunos juniores com base na correlação entre o original e o modelo e possibilita, diferentemente dos métodos tradicionais, desenvolver o raciocínio, estruturas intelectuais e operações lógicas dos alunos de maneira mais eficaz. Com o auxílio das abordagens epistemológicas, de atividade sistêmica e do meio, é determinada uma estratégia para o desenvolvimento do pensamento lógico dos alunos por meio da aprendizagem baseada em projetos, baseada na correlação entre o original e o modelo. Garante o desenvolvimento efetivo de a) atividade intelectual das crianças em idade escolar b) pensamento c) memória lógica. O estudo comprova a eficácia da tecnologia apresentada, que implica 1) imersão no projeto, além de especificar suas metas e objetivos; 2) organização e planejamento das atividades dos alunos; 3) elaboração das principais etapas do projeto; 4) realização do projeto e sua apresentação; 5) avaliando os resultados. Com base nos dados da pesquisa, foram destacados os seguintes critérios: análise, síntese, comparação, classificação, generalização e outros critérios que permitiram determinar três níveis de desenvolvimento do fenômeno em questão. Nosso método fornece uma melhoria significativa dos resultados da pesquisa e garante a formação de atividades de aprendizagem universais (ULAs) informativas, regulatórias e analíticas. A avaliação da eficácia e validade do método proposto é corroborada por cálculos para o critério de Fisher (critério φ *). Os resultados comparativos da pesquisa antes e após o experimento em alto nível são 3.564. Os valores empíricos obtidos de φ * estão na área de significância. H0 é rejeitado (o eixo de significância = 1.64-2.31). Assim, o método em questão tem um sério impacto no desenvolvimento do pensamento lógico através da aprendizagem baseada em projetos de alunos juniores.The article takes a new look at the method of developing logical thinking in junior students based on the correlation between the original and the model and making it possible, unlike traditional methods, to develop students’ speech thinking, intellectual structures, and logical operations more effectively. With the aid of the epistemological, systemic-activity, and milieu approaches, a strategy for developing students’ logical thinking through project-based learning that is premised on the correlation between the original and the model is determined. It ensures the effective development of a) schoolchildren’s intellectual activity b) thinking c) logical memory. The study proves the effectiveness of the presented technology, that implies 1) immersing in the project as well as specifying its goals and objectives; 2) organizing and planning students’ activities; 3) working out the main stages of the project; 4) carrying out the project and its presentation; 5) evaluating the results. Based on the research data, the following criteria were singled out analysis, synthesis, comparison, classification, generalization, and some other criteria, which allowed determining three levels of the development of the phenomenon in question. Our method provides for a significant improvement of the results of the research and ensures the formation of research, informational, regulatory, and analytical universal learning activities (ULAs). The assessment of the effectiveness and validity of the proposed method are corroborated by calculations for the Fisher’s criterion (φ*-criterion). The comparative results of the research before and after the experiment at the high level are 3.564. The obtained empirical values of φ * are in the area of significance. H0 is rejected (the significance axis = 1.64–2.31). Thus, the method in question has a serious impact on the development of logical thinking through project-based learning of junior students

Refractive properties of human adipose tissue at hyperthermic temperatures

The refractive index (RI) of human adipose tissu

Problems of single-industry towns: world experience and Russian practice

The process of industrialisation in Russia was accompanied by the creation of many cities, the economy of which is associated with a certain industry. At the same time, the city is completely dependent on one or more of the same type of enterprises. Such an enterprise is called a city-forming one, since it employs 30 % of all working people in the city, and their families make up half of the urban population. The dependence of the city on the enterprise that is one of the main problems, since the state of the enterprise directly affects the economy of the entire city. The activity of the enterprise determines the unemployment rate in the city, the size of the city budget and the state of engineering networks. In the case of a crisis and the shutdown of the enterprise, the economy of a single-industry city will face huge problems. The purpose of the study was to identify the problems of the Russian single-industry towns, and review foreign methods of leveling them. The object of the study were the Russian single-industry towns defined by the Russian Government Decree No. 1398-r dated on 29.07.2014 (revised on 21.01.2020) “On Approval of the List of Monoprofile Municipal Entities of the Russian Federation (Mono-Cities)”. The main research method was comparative analysis. The main problems of single-industry towns in Russia have been formulated: infrastructure provision and monoprofile economy. A comparative analysis of domestic and foreign experience in solving these problems is carried out and the directions of modernisation of Russian single-industry towns are proposed. Issues of legal support for the implementation of the proposed recommendations require further elaboration

Oxidative Modification of the Proteins of Breast and Cow Milk

One of the important modern characteristics of the nutritional and biological value of milk and dairy products is the antioxidant properties. The high stability and sensitivity of the determination of carbonyl derivatives of proteins, as well as the informative value of the action of antioxidants, allow using them as the markers of oxidative damage. The purpose of this paper was to compare the level of carbonyl derivatives of proteins in breast and cow milk. The determination of the oxidative modification of proteins was based on the reaction of carbonyl derivatives of amino acid residues with 2, 4-dinitrophenylhydrazine. The content of the products was determined during spontaneous and metal-catalyzed oxidative modification of the proteins. During the determination of the spontaneously formed carbonyl derivatives of the proteins, their significantly higher content in cow milk compared to breast milk was established. This increase ranged from 46% to 83% at different wavelengths. Thus, the determination of carbonyl derivatives of amino acid residues of the proteins made it possible to reveal significant differences in the antioxidant properties of breast and cow milk, manifested in a lower level of carbonyl derivatives in breast milk. The lower level of carbonyl derivatives in the composition of breast milk proteins is likely associated with the increased activity of the antioxidant system of breast milk or the increased rate of removal of damaged proteins upon activation of milk proteases. Keywords: carbonyl derivatives, oxidative modification, proteins, human milk, breast milk, metal-catalyze

L-NAME-induced preeclampsia: correction of functional disorders of the hemostasis system with resveratrol and nicorandil

Preeclampsia is a formidable disease of the second half of pregnancy, leading to severe complications, including disability and even death. Many authors have recognized the correlation between the severity of preeclampsia and the degree of disturbances in the hemostasis system. In this regard, the objective of this study was to assess inhibition of platelet aggregation and the possibility of its correction with resverаtrol and nicorand