Multi-vortex dynamics in junctions of charge density waves

Ground state reconstruction by creation of topological defects in junctions of CDWs is a convenient playground for modern efforts of field-effect transformations in strongly correlated materials with spontaneous symmetry breakings. Being transient, this effect contributes also to another new science of pump-induced phase transitions. We present a dynamical model for behavior of the CDW in restricted geometries of junctions under an applied voltage or a passing current. The model takes into account multiple interacting fields: the amplitude and the phase of the CDW complex order parameter, distributions of the electric field, the density and the current of various normal carriers. A particular challenge was to monitor the local conservation of the condensed and the normal charge densities. That was done easily invoking the chiral invariance and the associated anomaly, but prize is an unconventional Ginsburg-Landau type theory which is not analytic with respect to the order parameter. The numerical modeling poses unusual difficulties but still can demonstrate that vortices are nucleated at the junction boundary when the voltage across, or the current through, exceed a threshold.Comment: To be published in proceedings of the conference SUPERSTRIPES-2014, A. Bianconi ed., J. Supercond. Nov. Mag., (2015

A Tonks Giradeau Gas in the Presence of a Local Potential

The physics of a Tonks-Giradeau Gas in the presence of a local potential is studied. In order to evaluate the single particle density matrix (SPDM) of the many-body ground state, the Wiger-Jordan transformation is used. The eigenvector with the largest eigenvalue of the SPDM corresponds to the "Bose-Einstein Condensate"(BEC) State. We find that the "BEC" state density at the positon of the local potential decreases, as expected, in the case of a repulsive potential. For an attractive potential, it decreases or increases depending on the strength of the potential. The superfluidity of this system is investigated both numerically and perturbatively. An experimental method for detecting the effect of an impurity in a Tonks-Giradueau gas is discussed.Comment: 14 pages, 5 figure

Cracking the membrane lipid code.

Why has nature acquired such a huge lipid repertoire? Although it would be theoretically possible to make a lipid bilayer fulfilling barrier functions with only one glycerophospholipid, there are diverse and numerous different lipid species. Lipids are heterogeneously distributed across the evolutionary tree with lipidomes evolving in parallel to organismal complexity. Moreover, lipids are different between organs and tissues and even within the same cell, different organelles have characteristic lipid signatures. At the molecular level, membranes are asymmetric and laterally heterogeneous. This lipid asymmetry at different scales indicates that these molecules may play very specific molecular functions in biology. Some of these roles have been recently uncovered: lipids have been shown to be essential in processes such as hypoxia and ferroptosis or in protein sorting and trafficking but many of them remain still unknown. In this review we will discuss the importance of understanding lipid diversity in biology across scales and we will share a toolbox with some of the emerging technologies that are helping us to uncover new lipid molecular functions in cell biology and, step by step, crack the membrane lipid code

New constraints on the formation and settling of dust in the atmospheres of young M and L dwarfs

We obtained medium-resolution near-infrared spectra of seven young M9.5-L3 dwarfs classified in the optical. We aim to confirm the low surface gravity of the objects in the NIR. We also test whether atmospheric models correctly represent the formation and the settling of dust clouds in the atmosphere of young late-M and L dwarfs. We used ISAAC at VLT to obtain the spectra of the targets. We compared them to those of mature and young BD, and young late-type companions to nearby stars with known ages, in order to identify and study gravity-sensitive features. We computed spectral indices weakly sensitive to the surface gravity to derive near-infrared spectral types. Finally, we found the best fit between each spectrum and synthetic spectra from the BT-Settl 2010 and 2013 models. Using the best fit, we derived the atmospheric parameters of the objects and identify which spectral characteristics the models do not reproduce. We confirmed that our objects are young BD and we found NIR spectral types in agreement with the ones determined at optical wavelengths. The spectrum of the L2-gamma dwarf 2MASSJ2322-6151 reproduces well the spectrum of the planetary mass companion 1RXS J1609-2105b. BT-Settl models fit the spectra and the 1-5 $\mu$m SED of the L0-L3 dwarfs for temperatures between 1600-2000 K. But the models fail to reproduce the shape of the H band, and the NIR slope of some of our targets. This fact, and the best fit solutions found with super-solar metallicity are indicative of a lack of dust, in particular at high altitude, in the cloud models. The modeling of the vertical mixing and of the grain growth will be revised in the next version of the BT-Settl models. These revisions may suppress the remaining non-reproducibilities.Comment: Accepted in A&A, February 6, 201

The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus

Indexación: Web of Science; Scopus.Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply modifications in dendritic cytoskeleton. Rho GTPases are regulators of actin dynamics through their effector Rho kinase. We have reported that chronic stress promotes depressive-like behaviors in rats along with dendritic spine loss in apical dendrites of hippocampal pyramidal neurons, changes associated with Rho kinase activation. The present study proposes that the Rho kinase inhibitor Fasudil may prevent the stress-induced behavior and dendritic spine loss. Methods: Adult male Sprague-Dawley rats were injected with saline or Fasudil (i.p., 10 mg/kg) starting 4 days prior to and maintained during the restraint stress procedure (2.5 h/d for 14 days). Nonstressed control animals were injected with saline or Fasudil for 18 days. At 24 hours after treatment, forced swimming test, Golgi-staining, and immuno-western blot were performed. Results: Fasudil prevented stress-induced immobility observed in the forced swimming test. On the other hand, Fasudiltreated control animals showed behavioral patterns similar to those of saline-treated controls. Furthermore, we observed that stress induced an increase in the phosphorylation of MYPT1 in the hippocampus, an exclusive target of Rho kinase. This change was accompanied by dendritic spine loss of apical dendrites of pyramidal hippocampal neurons. Interestingly, increased pMYPT1 levels and spine loss were both prevented by Fasudil administration. Conclusion: Our findings suggest that Fasudil may prevent the development of abnormal behavior and spine loss induced by chronic stress by blocking Rho kinase activity.https://academic.oup.com/ijnp/article/20/4/336/263217

Damage Evolution in Quasi-Brittle Materials: Experimental Analysis by AE and Numerical Simulation

This work investigates the extension of a total-collapse prediction method to include local failures in quasi-brittle materials as they undergo damage processes. The analysis is experimentally conducted with acoustic emission data from a basalt specimen under a prescribed displacement loading test. The proposed failure index is compared with the well-established b-value to evaluate its usefulness; the simulation results are also used to further investigations. In particular, the simulations show that the parameter calculation can be carried out by indirectly estimating the elastic energy released within the system throughout the damage process, which cannot be measured directly. It is concluded that the proposed method is valid, consistently outperforming the b-value as a failure precursor throughout the experimental studies

Biological activities specified by antibiotic resistance plasmids

Bacteria can display resistance to a wide spectrum of noxious agents and environmental conditions, and these properties are often mediated by genes located on extrachromosomal DNA elements called plasmids. Replication, vertical and horizontal transmission and evolution of these elements are discussed, and examples of the genes responsible for the resistance phenotypes are given. Selective forces that drive the evolution of new combinations of bacterial properties of particular importance in clinical situations are analyse

Biological activities specified by antibiotic resistance plasmids

Bacteria can display resistance to a wide spectrum of noxious agents and environmental conditions, and these properties are often mediated by genes located on extrachromosomal DNA elements called plasmids. Replication, vertical and horizontal transmission and evolution of these elements are discussed, and examples of the genes responsible for the resistance phenotypes are given. Selective forces that drive the evolution of new combinations of bacterial properties of particular importance in clinical situations are analyse

The HARPS search for southern extra-solar planets XXXV. Planetary systems and stellar activity of the M dwarfs GJ 3293, GJ 3341, and GJ 3543

Context. Planetary companions of a fixed mass induce larger amplitude reflex motions around lower-mass stars, which helps make M dwarfs excellent targets for extra-solar planet searches. State of the art velocimeters with $\sim$1m/s stability can detect very low-mass planets out to the habitable zone of these stars. Low-mass, small, planets are abundant around M dwarfs, and most known potentially habitable planets orbit one of these cool stars. Aims. Our M-dwarf radial velocity monitoring with HARPS on the ESO 3.6m telescope at La Silla observatory makes a major contribution to this sample. Methods. We present here dense radial velocity (RV) time series for three M dwarfs observed over $\sim5$ years: GJ 3293 (0.42M$_\odot$), GJ 3341 (0.47M$_\odot$), and GJ 3543 (0.45M$_\odot$). We extract those RVs through minimum $\chi^2$ matching of each spectrum against a high S/N ratio stack of all observed spectra for the same star. We then vet potential orbital signals against several stellar activity indicators, to disentangle the Keplerian variations induced by planets from the spurious signals which result from rotational modulation of stellar surface inhomogeneities and from activity cycles. Results. Two Neptune-mass planets - $msin(i)=1.4\pm0.1$ and $1.3\pm0.1M_{nept}$ - orbit GJ 3293 with periods $P=30.60\pm0.02$ d and $P=123.98\pm0.38$ d, possibly together with a super-Earth - $msin(i)\sim7.9\pm1.4M_\oplus$ - with period $P=48.14\pm0.12\;d$. A super-Earth - $msin(i)\sim6.1M_\oplus$ - orbits GJ 3341 with $P=14.207\pm0.007\;d$. The RV variations of GJ 3543, on the other hand, reflect its stellar activity rather than planetary signals.Comment: Accepted for publication in A&A, 19 pages, 12 figures, 7 table