1,595 research outputs found
Enhanced non-quark-antiquark and non-glueball Nc behavior of light scalar mesons
We show that the latest and very precise dispersive data analyses require a
large and very unnat- ural fine-tuning of the 1/Nc expansion at Nc = 3 if the
f_0(600) and K(800) light scalar mesons are to be considered predominantly
quark-antiquark states, which is not needed for light vector mesons. For this,
we use scattering observables whose 1/Nc corrections are suppressed further
than one power of 1/Nc for quark-antiquark or glueball states, thus enhancing
contributions of other nature. This is achieved without using unitarized ChPT,
but if it is used we can also show that it is not just that the coefficients of
the 1/Nc expansion are unnatural, but that the expansion itself does not even
follow the expected 1/Nc scaling of a glueball or a quark-antiquark meson.Comment: Discussion disfavoring a glueball interpretation added. Version
published in Phys. Rev.
Continuum variational and diffusion quantum Monte Carlo calculations
This topical review describes the methodology of continuum variational and
diffusion quantum Monte Carlo calculations. These stochastic methods are based
on many-body wave functions and are capable of achieving very high accuracy.
The algorithms are intrinsically parallel and well-suited to petascale
computers, and the computational cost scales as a polynomial of the number of
particles. A guide to the systems and topics which have been investigated using
these methods is given. The bulk of the article is devoted to an overview of
the basic quantum Monte Carlo methods, the forms and optimisation of wave
functions, performing calculations within periodic boundary conditions, using
pseudopotentials, excited-state calculations, sources of calculational
inaccuracy, and calculating energy differences and forces
Quantum Monte Carlo study of a positron in an electron gas
Quantum Monte Carlo calculations of the relaxation energy, pair-correlation function, and annihilating-pair momentum density are presented for a positron immersed in a homogeneous electron gas. We find smaller relaxation energies and contact pair-correlation functions in the important low-density regime than predicted by earlier studies. Our annihilating-pair momentum densities have almost zero weight above the Fermi momentum due to the cancellation of electron-electron and electron-positron correlation effects
On Bloom type estimates for iterated commutators of fractional integrals
In this paper we provide quantitative Bloom type estimates for iterated commutators of fractional integrals improving and extending results from [15]. We give new proofs for those inequalities relying upon a new sparse domination that we provide as well in this paper and also in techniques de- veloped in the recent paper [22]. We extend as well the necessity established in [15] to iterated commutators providing a new proof. As a consequence of the preceding results we recover the one weight estimates in [7, 1] and es- tablish the sharpness in the iterated case. Our result provides as well a new characterization of the BMO space
Estudio in vitro de la actividad citotóxica de resinas dentales tipo BIS-GMA
Las resinas composites se emplean desde hace varias décadas en distintas aplicaciones
estomatológicas, volviéndose indispensables para lograr una alta calidad en los servicios modernos.
Uno de los monómeros acrílicos más utilizados en estos materiales poliméricos de recubrimiento
es el 2-bis-[p-(2-hidroxi-3-metacriloxipropoxi) fenil] propano, conocido comúnmente como Bis-
GMA. El conocimiento de las interacciones de estos materiales con el sistema biológico es de vital
importancia debido al uso tan difundido de los mismos en la práctica clínica. El comportamiento de
una célula viva en contacto con un material extraño es un problema esencial en las aplicaciones
biomédicas de polímeros sintéticos. Los ensayos in vitro son sistemas muy útiles para la evaluación
de los efectos biológicos de los biomateriales.
En el laboratorio de Inmunofarmacología del INOR se llevó a cabo la evaluación de la
toxicidad de dos resinas dentales tipo Bis-GMA producidas por el Centro de Biomateriales de la
Universidad de La Habana: el Obtudent Fotocurado (FC), resina fotopolimerizable para restauraciones
dentales y el Cubridem Autocurado (AC), sellante dental para fosas y fisuras. Este estudio
forma parte de las evaluaciones preclínicas biológicas de biomateriales y equipos médicos
implantables que se lleva a cabo en Cuba a través de la Red Funcional de Implantología del
Ministerio de Salud Pública. Se aplicó el método de citotoxicidad in vitro descrito por Stanley para
la evaluación toxicológica de materiales dentales. Ambos composites resultaron citotóxicos para
la línea de fibroblastos L929, lo que se corresponde con lo descrito en la literatura para este tipo
de material. Su citotoxicidad se encontró en el rango de la de los análogos comerciales evaluados.Peer Reviewe
Systemic Design for Food Self-Sufficiency in Urban Areas
This article adopts a systemic approach to address the problem of the operationalization of relationships between actors conducive to food self-sufficiency in urban areas. Through the use of Social Network Analysis (SNA), the literature on urban agriculture was analyzed, detecting eight key trends and topic areas. This information was used to design a generic recursive organizational structure with the identification of the key roles and functions for management and governance in the multi-level and multi-stakeholder relationships of a sustainable urban self-sufficient food production system, inspired by the principles of complexity management and organizational cybernetics. Methodologically, this is the first application that combines the exploratory capability of SNA and the recursive structure of the Viable System Model (VSM) to propose applicable organizational structures in any urban area, suggesting a new route for the study and application of systemic thinking in the development of urban agriculture schemes. However, due to the conceptual nature of this work, this study opens a discussion on how we can rethink interactions to seek continuous adaptation in food self-sufficiency, provide tools that foster inclusion, and adapt to every context to support the relevant actors and academics in urban agriculture.</jats:p
Framework for constructing generic Jastrow correlation factors
We have developed a flexible framework for constructing Jastrow factors which
allows for the introduction of terms involving arbitrary numbers of particles.
The use of various three- and four-body Jastrow terms in quantum Monte Carlo
calculations is investigated, including a four-body van der Waals-like term,
and anisotropic terms. We have tested these Jastrow factors on one- and
two-dimensional homogeneous electron gases, the Be, B, and O atoms, and the
BeH, HO, N, and H molecules. Our optimized Jastrow factors retrieve
more than 90% of the fixed-node diffusion Monte Carlo correlation energy in
variational Monte Carlo for each system studied.Comment: 17 pages, 4 figure
Detection and quantification of nitric oxide–derived oxidants in biological systems
The free radical nitric oxide (NO) exerts biological effects through the direct and reversible interaction with specific targets (e.g. soluble guanylate cyclase) or through the generation of secondary species, many of which can oxidize, nitrosate or nitrate biomolecules. The NO -derived reactive species are typically short-lived, and their preferential fates depend on kinetic and compartmentalization aspects. Their detection and quantification
are technically challenging. In general, the strategies employed are based either on the detection of relatively stable end products or on the use of synthetic probes, and they are not always selective for a particular species. In this study, we describe the biologically relevant characteristics of the reactive species formed downstream from NO , and we discuss the approaches currently available for the analysis of NO , nitrogen dioxide (NO2 ), dinitrogen trioxide (N2O3), nitroxyl (HNO), and peroxynitrite (ONOO /ONOOH), as well as peroxynitrite-derived
hydroxyl (HO) and carbonate anion (CO3) radicals. We also discuss the biological origins of and analytical tools for detecting nitrite (NO2), nitrate (NO3), nitrosyl–metal complexes, S-nitrosothiols, and 3-nitrotyrosine. Moreover, we highlight state– of–the–art methods, alert readers to caveats of widely used techniques, and encourage retirement of approaches that have been supplanted by more reliable and selective tools for detecting and measuring NO -derived oxidants. We emphasize that the use of appropriate analytical methods needs to be strongly grounded in a chemical and biochemical understanding of the species and mechanistic pathways involveAgencia Nacional de Investigación e Innovación FCE_1_2017_1_136043Comisión Sectorial de Investigación Científica (CSIC)Universidad de la República. Espacio Interdisciplinari
Calculating with light using a chip-scale all-optical abacus
This is the final version of the article. Available from Springer Nature via the DOI in this record.Machines that simultaneously process and store multistate data at one and the same location can provide a new class of fast, powerful and efficient general-purpose computers. We demonstrate the central element of an all-optical calculator, a photonic abacus, which provides multistate compute-and-store operation by integrating functional phase-change materials with nanophotonic chips. With picosecond optical pulses we perform the fundamental arithmetic operations of addition, subtraction, multiplication, and division, including a carryover into multiple cells. This basic processing unit is embedded into a scalable phase-change photonic network and addressed optically through a two-pulse random access scheme. Our framework provides first steps towards light-based non-von Neumann arithmetic.The authors acknowledge support by Deutsche Forschungsgemeinschaft (DFG) grants PE 1832/2-1 and EPSRC grant EP/J018783/1. M.S. acknowledges support from the Karlsruhe School of Optics and Photonics (KSOP) and the Stiftung der Deutschen Wirtschaft (sdw). C.R. is grateful to JEOL UK and the Clarendon Fund for funding his graduate studies. H.B. acknowledges support from the John Fell Fund and the EPSRC (EP/J00541X/2 and EP/J018694/1). The authors also acknowledge support from the DFG and the State of Baden-Württemberg through the DFG-Center for Functional Nanostructures (CFN). The authors thank S. Diewald for assistance with device fabrication
Comparación de citología mediante aspirado de aguja fina e histología en el diagnóstico de lipidosis hepática en bovinos de matadero
El objetivo de este estudio fue comparar resultados de citología e histología en la detección de acúmulo de lípido hepatocelular en bovinos. La lipidosis hepática en ganado lechero es una enfermedad de gran importancia clínica y económica. La citología de aspirado de aguja fina (AAF) ha sido descrita como una técnica capaz de identificar lipidosis hepática en bovinos, sin embargo se carece de estudios que evalúen la exactitud del método. Este estudio corresponde a un primer paso para probar nuestra hipótesis de que la citología de AAF es un método de una exactitud razonable, económico y practicable para diagnosticar lipidosis hepática en bovinos. Se obtuvo 73 muestras a partir de hígados de matadero inmediatamente post mortem. Utilizando una escala de 1 a 4 se determinó la severidad de la lesión tanto para el porcentaje de células afectadas como para el promedio de citoplasma afectado. Se utilizaron muestras pareadas que representaron un espectro de las lesiones. La correlación entre el grado de afección de hepatocitos y citoplasma entre citología e histología fue altamente significativa.
El puntaje dado para porcentaje de hepatocitos afectados fue diferente en ≤1 punto entre citología e histología en el 73% de los casos. Para el caso de porcentaje de citoplasma afectado esta diferencia de ≤1 punto entre ambas técnicas se presentó en el 95% de los casos. La prueba de concordancia de Kappa entre citología e histología fue adecuada. Estos hallazgos sugieren que la citología de aspirado de aguja fina puede ser un método aceptable para diagnosticar hígado graso en ganado bovino. Se requieren más estudios en animales vivos con sospecha clínica de lipidosis hepática
- …