Calculation of Nuclear Magnetic Shielding Constants in Two Simple Systems

The nuclear magnetic shielding constants of two simple systems are calculated explicitly. These systems are (1) a nucleus μ at a distance R from a hydrogenic atom of charge ζe in the presence of an external electric field, and (2) a nucleus μ of a hydrogenic atom of charge ζe in the presence of a point charge at R with the result expanded in inverse powers of R. These calculations should prove useful in understanding the long‐range contributions of functional groups and neighboring molecules to observed chemical shifts of molecules

Genome analysis of a highly virulent serotype 1 strain of streptococcus pneumoniae from West Africa

Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and bacteremia, estimated to cause 2 million deaths annually. The majority of pneumococcal mortality occurs in developing countries, with serotype 1 a leading cause in these areas. To begin to better understand the larger impact that serotype 1 strains have in developing countries, we characterized virulence and genetic content of PNI0373, a serotype 1 strain from a diseased patient in The Gambia. PNI0373 and another African serotype 1 strain showed high virulence in a mouse intraperitoneal challenge model, with 20% survival at a dose of 1 cfu. The PNI0373 genome sequence was similar in structure to other pneumococci, with the exception of a 100 kb inversion. PNI0373 showed only15 lineage specific CDS when compared to the pan-genome of pneumococcus. However analysis of non-core orthologs of pneumococcal genomes, showed serotype 1 strains to be closely related. Three regions were found to be serotype 1 associated and likely products of horizontal gene transfer. A detailed inventory of known virulence factors showed that some functions associated with colonization were absent, consistent with the observation that carriage of this highly virulent serotype is unusual. The African serotype 1 strains thus appear to be closely related to each other and different from other pneumococci despite similar genetic content

Derivation of the Zakharov equations

This paper continues the study of the validity of the Zakharov model describing Langmuir turbulence. We give an existence theorem for a class of singular quasilinear equations. This theorem is valid for well-prepared initial data. We apply this result to the Euler-Maxwell equations describing laser-plasma interactions, to obtain, in a high-frequency limit, an asymptotic estimate that describes solutions of the Euler-Maxwell equations in terms of WKB approximate solutions which leading terms are solutions of the Zakharov equations. Because of transparency properties of the Euler-Maxwell equations, this study is led in a supercritical (highly nonlinear) regime. In such a regime, resonances between plasma waves, electromagnetric waves and acoustic waves could create instabilities in small time. The key of this work is the control of these resonances. The proof involves the techniques of geometric optics of Joly, M\'etivier and Rauch, recent results of Lannes on norms of pseudodifferential operators, and a semiclassical, paradifferential calculus

Scattering for the Zakharov system in 3 dimensions

We prove global existence and scattering for small localized solutions of the Cauchy problem for the Zakharov system in 3 space dimensions. The wave component is shown to decay pointwise at the optimal rate of t^{-1}, whereas the Schr\"odinger component decays almost at a rate of t^{-7/6}.Comment: Minor changes and referee's comments include

Correlations derived from Modern Nucleon-Nucleon Potentials

Various modern nucleon-nucleon (NN) potentials yield a very accurate fit to the nucleon-nucleon scattering phase shifts. The differences between these interactions in describing properties of nuclear matter are investigated. Various contributions to the total energy are evaluated employing the Hellmann - Feynman theorem. Special attention is paid to the two-nucleon correlation functions derived from these interactions. Differences in the predictions of the various interactions can be traced back to the inclusion of non-local terms.Comment: 7 pages, 4 figures include

Identifying nonlinear wave interactions in plasmas using two-point measurements: a case study of Short Large Amplitude Magnetic Structures (SLAMS)

A framework is described for estimating Linear growth rates and spectral energy transfers in turbulent wave-fields using two-point measurements. This approach, which is based on Volterra series, is applied to dual satellite data gathered in the vicinity of the Earth's bow shock, where Short Large Amplitude Magnetic Structures (SLAMS) supposedly play a leading role. The analysis attests the dynamic evolution of the SLAMS and reveals an energy cascade toward high-frequency waves.Comment: 26 pages, 13 figure

Henri Temianka Correspondence; (lte)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/3156/thumbnail.jp

Henri Temianka Correspondence; (lte)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/3170/thumbnail.jp

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue

The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria. The CD4(+) T cell response to pneumococcus is increasingly recognised as an important mediator of immunity that protects against invasive disease, with data suggesting a critical role for Th17 cells in mucosal clearance. By assessing CD4 T cell proliferative responses we demonstrate age-related sequestration of Th1 and Th17 CD4(+) T cells reactive to pneumococcal protein antigens within mucosal lymphoid tissue. CD25(hi) T cell depletion and utilisation of pneumococcal specific MHCII tetramers revealed the presence of antigen specific Tregs that utilised CTLA-4 and PDL-1 surface molecules to suppress these responses. The balance between mucosal effector and regulatory CD4(+) T cell immunity is likely to be critical to pneumococcal commensalism and the prevention of unwanted pathology associated with carriage. However, if dysregulated, such responses may render the host more susceptible to invasive pneumococcal infection and adversely affect the successful implementation of both polysaccharide-conjugate and novel protein-based pneumococcal vaccines

Freely decaying weak turbulence for sea surface gravity waves

We study numerically the generation of power laws in the framework of weak turbulence theory for surface gravity waves in deep water. Starting from a random wave field, we let the system evolve numerically according to the nonlinear Euler equations for gravity waves in infinitely deep water. In agreement with the theory of Zakharov and Filonenko, we find the formation of a power spectrum characterized by a power law of the form of $|{\bf k}|^{-2.5}$.Comment: 4 pages, 3 figure