343 research outputs found

    Investigation into Travel Modes for Transit Oriented Development: Employees' Travel Survey of Kelvin Grove Urban Village

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    Travel surveys were conducted for collecting data related to visitors travel to Kelvin Grove Urban Village (KGUV). KGUV has employees of retail shopping centre, employees of educational land use, school and university students and shoppers as visitors of this area. As a part of data collection process a travel surveys was undertaken for employees and students of KGUV. This document contains the questionnaire form used to collect the data related to employee travel. Similar questions were asked to the students of KGUV. The instructions given for filling out the survey were not included in the actual questionnaire form as internet based surveys were undertaken. This form was used for personal interviews and Computer Assisted Personal Interview (CAPI) surveys undertaken for employees of the retail shopping centre

    Hepatoprotective Effect of Cassia Fistula Linn.

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    A number of herbal preparations are used throughout the world for the management of the hepatic disorders. However, many of them have not been investigated for their described effects. Cassia fistula Linn. is one such drug used in the treatment of hepatitis in folk medicine. Therefore, an attempt was made to investigate the hepatoprotective effect of leaves and bark of Cassia fistula against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. Sixty albino Wistar rats were divided into six equal groups of 10. Four groups received extracts leaves/bark of Cassia fistula and intraperitoneal (i.p.) CCl4 (0.2 ml/100 g) either before or after administration of extracts. Two groups were controls, one treated with CCl4 and one with normal saline. Liver damage was assessed by plasma concentration of bilirubin and enzyme activities of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase. Treatment with aqueous extract of leaves and bark significantly reduced CCl4 -induced elevation in plasma enzyme and bilirubin concentration in rats. This study demonstrated that CCl4 -induced liver damage in rats can be ameliorated by treatment of extracts from leaves and bark

    Impacts of leaf extract of Catharanthus roseus (L.) on seed mycoflora of soybean

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    Present research communication deals with study impact of Catharanthus roseus (L.) leaf extract on seed borne fungi of soybean seeds.&nbsp

    Evaluation of leaf extract of Lantana camara aginast seed mycoflora - biopesticides approach

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    The Seed treatment with pant extract of Lantana camara does not have any adverse effect on the germinated of seeds even after the treatment for 30 minutes. The seed were treated with aqneous extract, alcoholic extract, and ethyl acetate extract of Lantana camara leavers for 5 minutes, 15 minutes and 30 minutes. It is evident that the treatment of ethyl acetate extract for 30 minutes inhibited the growth of dominant fungi like curvularia lunata A.flavus, A.niger and fusarium moniliforme. So the ethylacetate extract of leaves of Lantana camara can be utilised for the biological control of seeds borne fungi of soybean. So the seed treatment of plant extract will not cause any problem of pollution and the chemical of plant extracts are easily degraded in the soil, So the plant extract of Lantana camara can be used as biopesticide.&nbsp

    Control of fungi associated with green gram seeds by using Trichoderma species

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    In the recent years, the biological control has received a worldwide attention and is being integrated effectively with other pesticides. Moreover, in the context of environmental pollution the use of biological agents is considered quite safe. Three Trichoderma species viz. T. viride, T. harzionum and Trichoderma sp. (Local) were evaluated against Aspergillus niger, A. flavus, Alternaria tenuis, Fusarium oxysporium, Penicillium citrinum, Drechslera longirostrata and Fusarium solani. All the Trichoderma species were effective against above pathogens but Trichoderma (Local) proved to be superior for inhibition of the above pathogen as compared to other Trichoderma species

    �Synchronous Modulation In An Inverter Fed Motor Drive For Recovering Energy From Matching Long Cable ��

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    In this paper, we understood the significance of bit rate investigation of the approaching bundle. We additionally comprehended that if the bit rate is not dissected, then there is wastefulness in system execution. This examination study will demonstrate a decent base for further research in the territory of bit rate investigation of bundle landings. In this paper we had broke down the throughput, parcel delay, bundle conveyance proportion, jitter, vitality devoured and the examination as for no. of bundles sent is performed. Thusly we can accomplish the objective of enhancing bit rate bundle investigation coming about system proficiency. The most recent adaptation of system test system will be most useful in development of system and follow document in it is additionally helpful. In future, the framework could be created on the equipment and the execution assessment could be checked continuously. The deferral is an imperative parameter if there should arise an occurrence of ongoing activity. The postponement ought to be diminished or else it prompts unsafe circumstance on the off chance that hard continuous frameworks. Thus, it would be an awesome future work to build up the framework on the equipment and checking of execution assessment progressively

    Mycoflora associated with Pigeon pea and Chickpea

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    Pigeonpea (Cajanu. cajan.) and Chick Pea (Cicer arietinum) are major pulse crops grown in India. The seed mycoflora was screened by using agar plate method. seeds of varieties of these pulse crops was used in the study and results were obtained from untreated and treated seeds. The untreated seeds were found to be associated with highest percent incidence of mycoflora. In case of untreated seeds the percent incidence of Aspergillus flavus (30%) was the highest followed by     A. niger (25%), Penicillium notatum (20 %), Cladosporium herbarum (18%), where as all other fungi were within the range of (3 to 15%)

    Studies on Routine Urine Analysis of Urinary Tract Infection

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    The data obtained form routine urine analysis Viz physical examination, chemical examination and microscopic examination revealed that, in case of physical examination of urine sample is yellow to milky colour was observed while in case of appearance it was turbid to hazy where as putrefied odor was observed in all sample n=10. The data obtained form chemical examination indicates presence of albumin in all sample. Bile salt is present only one sample. The data obtained form microscopic examination revealed that pus cell count increases in all samples suffering from Urinary tract infection (uti)

    Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death

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    GABARAP belongs to an evolutionary highly conserved gene family that has a fundamental role in autophagy. There is ample evidence for a crosstalk between autophagy and apoptosis as well as the immune response. However, the molecular details for these interactions are not fully characterized. Here, we report that the ablation of murine GABARAP, a member of the Atg8/LC3 family that is central to autophagosome formation, suppresses the incidence of tumor formation mediated by the carcinogen DMBA and results in an enhancement of the immune response through increased secretion of IL-1β, IL-6, IL-2 and IFN-γ from stimulated macrophages and lymphocytes. In contrast, TGF-β1 was significantly reduced in the serum of these knockout mice. Further, DMBA treatment of these GABARAP knockout mice reduced the cellularity of the spleen and the growth of mammary glands through the induction of apoptosis. Gene expression profiling of mammary glands revealed significantly elevated levels of Xaf1, an apoptotic inducer and tumor-suppressor gene, in knockout mice. Furthermore, DMBA treatment triggered the upregulation of pro-apoptotic (Bid, Apaf1, Bax), cell death (Tnfrsf10b, Ripk1) and cell cycle inhibitor (Cdkn1a, Cdkn2c) genes in the mammary glands. Finally, tumor growth of B16 melanoma cells after subcutaneous inoculation was inhibited in GABARAP-deficient mice. Together, these data provide strong evidence for the involvement of GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response

    Lung Adenocarcinoma Cell Sensitivity to Chemotherapies: A Spotlight on Lipid Droplets and SREBF1 Gene

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    To explore the relationship between cancer cell SREBF1 expression, lipid droplets (LDs) formation, and the sensitivity to chemotherapies, we cultured lung adenocarcinoma cells H1299 (with LD) and H1563 (without LD) in a serum-free basal medium (BM) or neutrophil degranulation products containing medium (NDM), and tested cell responses to cisplatin and etoposide. By using the DESeq2 Bioconductor package, we detected 674 differentially expressed genes (DEGs) associated with NDM/BM differences between two cell lines, many of these genes were associated with the regulation of sterol and cholesterol biosynthesis processes. Specifically, SREBF1 markedly declined in both cell lines cultured in NDM or when treated with chemotherapeutics. Despite the latter, H1563 exhibited LD formation and resistance to etoposide, but not to cisplatin. Although H1299 cells preserved LDs, these cells were similarly sensitive to both drugs. In a cohort of 292 patients with non-small-cell lung cancer, a lower SREBF1 expression in tumors than in adjacent nontumor tissue correlated with overall better survival, specifically in patients with adenocarcinoma at stage I. Our findings imply that a direct correlation between SREBF1 and LD accumulation can be lost due to the changes in cancer cell environment and/or chemotherapy. The role of LDs in lung cancer development and response to therapies remains to be examined in more detail.The study was supported by German Center for Lung Research, grants number 82DZL002B1 (Janciauskiene) and 82DZL00402 (Schneider).S
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