41 research outputs found

    Assessing the role of EO in biodiversity monitoring: options for integrating in-situ observations with EO within the context of the EBONE concept

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    The European Biodiversity Observation Network (EBONE) is a European contribution on terrestrial monitoring to GEO BON, the Group on Earth Observations Biodiversity Observation Network. EBONE’s aims are to develop a system of biodiversity observation at regional, national and European levels by assessing existing approaches in terms of their validity and applicability starting in Europe, then expanding to regions in Africa. The objective of EBONE is to deliver: 1. A sound scientific basis for the production of statistical estimates of stock and change of key indicators; 2. The development of a system for estimating past changes and forecasting and testing policy options and management strategies for threatened ecosystems and species; 3. A proposal for a cost-effective biodiversity monitoring system. There is a consensus that Earth Observation (EO) has a role to play in monitoring biodiversity. With its capacity to observe detailed spatial patterns and variability across large areas at regular intervals, our instinct suggests that EO could deliver the type of spatial and temporal coverage that is beyond reach with in-situ efforts. Furthermore, when considering the emerging networks of in-situ observations, the prospect of enhancing the quality of the information whilst reducing cost through integration is compelling. This report gives a realistic assessment of the role of EO in biodiversity monitoring and the options for integrating in-situ observations with EO within the context of the EBONE concept (cfr. EBONE-ID1.4). The assessment is mainly based on a set of targeted pilot studies. Building on this assessment, the report then presents a series of recommendations on the best options for using EO in an effective, consistent and sustainable biodiversity monitoring scheme. The issues that we faced were many: 1. Integration can be interpreted in different ways. One possible interpretation is: the combined use of independent data sets to deliver a different but improved data set; another is: the use of one data set to complement another dataset. 2. The targeted improvement will vary with stakeholder group: some will seek for more efficiency, others for more reliable estimates (accuracy and/or precision); others for more detail in space and/or time or more of everything. 3. Integration requires a link between the datasets (EO and in-situ). The strength of the link between reflected electromagnetic radiation and the habitats and their biodiversity observed in-situ is function of many variables, for example: the spatial scale of the observations; timing of the observations; the adopted nomenclature for classification; the complexity of the landscape in terms of composition, spatial structure and the physical environment; the habitat and land cover types under consideration. 4. The type of the EO data available varies (function of e.g. budget, size and location of region, cloudiness, national and/or international investment in airborne campaigns or space technology) which determines its capability to deliver the required output. EO and in-situ could be combined in different ways, depending on the type of integration we wanted to achieve and the targeted improvement. We aimed for an improvement in accuracy (i.e. the reduction in error of our indicator estimate calculated for an environmental zone). Furthermore, EO would also provide the spatial patterns for correlated in-situ data. EBONE in its initial development, focused on three main indicators covering: (i) the extent and change of habitats of European interest in the context of a general habitat assessment; (ii) abundance and distribution of selected species (birds, butterflies and plants); and (iii) fragmentation of natural and semi-natural areas. For habitat extent, we decided that it did not matter how in-situ was integrated with EO as long as we could demonstrate that acceptable accuracies could be achieved and the precision could consistently be improved. The nomenclature used to map habitats in-situ was the General Habitat Classification. We considered the following options where the EO and in-situ play different roles: using in-situ samples to re-calibrate a habitat map independently derived from EO; improving the accuracy of in-situ sampled habitat statistics, by post-stratification with correlated EO data; and using in-situ samples to train the classification of EO data into habitat types where the EO data delivers full coverage or a larger number of samples. For some of the above cases we also considered the impact that the sampling strategy employed to deliver the samples would have on the accuracy and precision achieved. Restricted access to European wide species data prevented work on the indicator ‘abundance and distribution of species’. With respect to the indicator ‘fragmentation’, we investigated ways of delivering EO derived measures of habitat patterns that are meaningful to sampled in-situ observations

    High-resolution study of 0+ and 2+ excitations in 168Er with the (p,t) reaction

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    Excited states in the deformed nucleus 168Er have been studied with high-energy resolution, in the (p, t ) reaction, with the Munich Q3D spectrograph. A number of 25 excited 0+ states (four tentative) and 63 2+ states have been assigned up to 4.0 MeV excitation energy. This unusually rich characterization of the 0+ and 2+ states in a deformed nucleus, close to a complete level scheme, offers a unique opportunity to check, in detail, models of nuclear structure that incorporate many excitation modes. A comparison of the experimental data is made with two such models: the quasiparticle-phonon model (QPM), and the projected shell model (PSM). The PSM wave functions appear to contain fewer correlations than those of the QPM and than required by the data

    Lymphovascular and perineural invasion as selection criteria for adjuvant therapy in intrahepatic cholangiocarcinoma: a multi-institution analysis

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    AbstractObjectivesCriteria for the selection of patients for adjuvant chemotherapy in intrahepatic cholangiocarcinoma (IHCC) are lacking. Some authors advocate treating patients with lymph node (LN) involvement; however, nodal assessment is often inadequate or not performed. This study aimed to identify surrogate criteria based on characteristics of the primary tumour.MethodsA total of 58 patients who underwent resection for IHCC between January 2000 and January 2010 at any of three institutions were identified. Primary outcome was overall survival (OS).ResultsMedian OS was 23.0months. Median tumour size was 6.5cm and the median number of lesions was one. Overall, 16% of patients had positive margins, 38% had perineural invasion (PNI), 40% had lymphovascular invasion (LVI) and 22% had LN involvement. A median of two LNs were removed and a median of zero were positive. Lymph nodes were not sampled in 34% of patients. Lymphovascular and perineural invasion were associated with reduced OS [9.6months vs. 32.7months (P= 0.020) and 10.7months vs. 32.7months (P= 0.008), respectively]. Lymph node involvement indicated a trend towards reduced OS (10.7months vs. 30.0months; P= 0.063). The presence of either LVI or PNI in node-negative patients was associated with a reduction in OS similar to that in node-positive patients (12.1months vs. 10.7months; P= 0.541). After accounting for adverse tumour factors, only LVI and PNI remained associated with decreased OS on multivariate analysis (hazard ratio4.07, 95% confidence interval 1.60–10.40; P= 0.003).ConclusionsLymphovascular and perineural invasion are separately associated with a reduction in OS similar to that in patients with LN-positive disease. As nodal dissection is often not performed and the number of nodes retrieved is frequently inadequate, these tumour-specific factors should be considered as criteria for selection for adjuvant chemotherapy

    Isospin symmetry in B(E2) values: Coulomb excitation study of Mg-21

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    The TzT_z~=~−32-\frac{3}{2} nucleus 21{}^{21}Mg has been studied by Coulomb excitation on 196{}^{196}Pt and 110{}^{110}Pd targets. A 205.6(1)-keV γ\gamma-ray transition resulting from the Coulomb excitation of the 52+\frac{5}{2}^+ ground state to the first excited 12+\frac{1}{2}^+ state in 21{}^{21}Mg was observed for the first time. Coulomb excitation cross-section measurements with both targets and a measurement of the half-life of the 12+\frac{1}{2}^+ state yield an adopted value of B(E2;52+→12+)B(E2;\frac{5}{2}^+\rightarrow\frac{1}{2}^+)~=~13.3(4)~W.u. A new excited state at 1672(1)~keV with tentative 92+\frac{9}{2}^+ assignment was also identified in 21{}^{21}Mg. This work demonstrates large difference of the B(E2;52+→12+)B(E2;\frac{5}{2}^+\rightarrow\frac{1}{2}^+) values between TT~=~32\frac{3}{2}, AA~=~21 mirror nuclei. The difference is investigated in the shell-model framework employing both isospin conserving and breaking USD interactions and using modern \textsl{ab initio} nuclear structure calculations, which have recently become applicable in the sdsd shell.Comment: 8 pages, 6 figures, submitted to Phys. Rev. C, Rapid Communicatio

    Single-neutron orbits near Ni-78: Spectroscopy of the N=49 isotope Zn-79

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    5 pags., 6 figs.Single-neutron states in the , isotope 79Zn have been populated using the 78Zn(d, p)79Zn transfer reaction at REX-ISOLDE, CERN. The experimental setup allowed the combined detection of protons ejected in the reaction, and of γ rays emitted by 79Zn. The analysis reveals that the lowest excited states populated in the reaction lie at approximately 1 MeV of excitation, and involve neutron orbits above the shell gap. From the analysis of γ-ray data and of proton angular distributions, characteristic of the amount of angular momentum transferred, a configuration was assigned to a state at 983 keV. Comparison with large-scale-shell-model calculations supports a robust neutron shell-closure for 78Ni. These data constitute an important step towards the understanding of the magicity of 78Ni and of the structure of nuclei in the region.This work was supported by the European Commission through the Marie Curie Actions Contracts Nos. PIEFGA-2011-30096 (R.O.) and PIEFGA-2008-219175 (J.P.), by the Spanish Ministerio de Ciencia e Innovación under contracts FPA2009-13377-C02 and FPA2011-29854-C04, by the Spanish MEC Consolider – Ingenio 2010, Project No. CDS2007-00042 (CPAN), by FWO-Vlaanderen (Belgium), by GOA/2010/010 (BOF KU Leuven), by the Interuniversity Attraction Poles Programme initiated by the Belgian Science Policy Office (BriX network P7/12), by the European Union Seventh Framework Programme through ENSAR, contract no. RII3-CT-2010-262010, and by the German BMBF under contracts 05P09PKCI5, 05P12PKFNE, 05P12RDCIA and 06DA9036I. R.O., R.C., J.F.W.L., V.L. and J.F.S. also acknowledge support from STFC, Grant Nos. PP/F000944/1, ST/F007590/1, and ST/J000183/2

    Polyamine Sharing between Tubulin Dimers Favours Microtubule Nucleation and Elongation via Facilitated Diffusion

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    We suggest for the first time that the action of multivalent cations on microtubule dynamics can result from facilitated diffusion of GTP-tubulin to the microtubule ends. Facilitated diffusion can promote microtubule assembly, because, upon encountering a growing nucleus or the microtubule wall, random GTP-tubulin sliding on their surfaces will increase the probability of association to the target sites (nucleation sites or MT ends). This is an original explanation for understanding the apparent discrepancy between the high rate of microtubule elongation and the low rate of tubulin association at the microtubule ends in the viscous cytoplasm. The mechanism of facilitated diffusion requires an attraction force between two tubulins, which can result from the sharing of multivalent counterions. Natural polyamines (putrescine, spermidine, and spermine) are present in all living cells and are potent agents to trigger tubulin self-attraction. By using an analytical model, we analyze the implication of facilitated diffusion mediated by polyamines on nucleation and elongation of microtubules. In vitro experiments using pure tubulin indicate that the promotion of microtubule assembly by polyamines is typical of facilitated diffusion. The results presented here show that polyamines can be of particular importance for the regulation of the microtubule network in vivo and provide the basis for further investigations into the effects of facilitated diffusion on cytoskeleton dynamics

    Sites’ Description. BIO SOS Biodiversity Multisource Monitoring System: from Space TO Species (BIO SOS) Deliverable D2.2, pp126 http://www.biosos.wur.nl/UK/Deliverables/

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    Eleven test sites in Europe (mainly in the Mediterranean) were selected for testing and ground verification of the methods to be developed in BIO_SOS. All sites are important areas for the conservation of biodiversity. Their landscape structure is analysed as well as the pressures and threats of each site, recognizing habitat loss and fragmentation to be of seminal importance. The analysis concludes with the identification of key biodiversity indicators that need to be monitored, and the definition of the spatial and temporal resolution of this monitoring
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